• Korean Journal of Pharmacognosy
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• v.39 no.4
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• pp.341-346
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• 2008

The effects of the ethanol extracts from Gynostemma pentaphyllum (GP extracts) on body weights, grip strengths, endurances and catecholamine levels after electric footshock (EF) stress in mice and rats were investigated. The animals were treated with GP extracts (50 mg/kg/day, p.o.) for 21 days before exposure to EF (duration and interval 10 sec for 3 min, 2 mA) once a day. The increases in body weights were delayed by 13.1% of the control levels by EF-induced stress in mice, which were recovered to 24.1% of the control levels in GP extract-treated groups. The grip strengths were significantly decreased by EF stress in mice and the EF-stressed groups treated with GP extracts increased grip strengths to 115.2% compared to control levels. The endurance times by forced swimming, which reduced significantly by EF stress, were also maintained similar to control levels by GP extracts in rats. In addition, the levels of norepinephrine and epinephrine in serum and brain, and dopamine in brain were significantly increased to 17.5-95.0% of the control levels after exposure of EF stress in mice. However, EF stressinduced increases in norepinephrine and epinephrine in serum were reduced to 17.1-17.3% of the control levels by treatments of GP extracts, and those in dopamine, norepinephrine and epinephrine in brain were also reduced to 5.0-19.5%. These results suggest that GP extracts showed the protective effects on EF stress-induced physiological functions and can be developed as the promising anti-stress agents.

• Journal of Community Nutrition
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• v.6 no.2
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• pp.103-109
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• 2004

Body antioxidant status is an important factor for the prevention of many chronic diseases in the elderly. This study was done to investigate antioxidant status and its relationship to immune response by measuring plasma cytokine (IL-2 and IL-6) levels in elderly women. Subjects were 76 elderly women aged over 60 years, visiting Jangwhi Social Welfare Center of Seongbook-Gu in Seoul. Subjects were divided into 3 groups according to age (< 65, 65 - 74, > 75). Dietary intakes were assessed by semi-quantitative food frequency questionnaires (SFFQ). Plasma vitamin C level was measured by 2,4-dinitrophenylhydrazine method and plasma levels of vitamin E, A and ${\beta}$-carotene were measured by HPLC. Plasma levels of IL-2 and IL-6 were determined with a solid phase sandwich enzyme linked-immuno-sorbent assay (ELISA) using commercial kits. The average intakes of antioxidant vitamins were 96.3mg (137.5% of RDA) for vitamin C and 523.3 ${\mu}$gRE (74.8% of RDA) for vitamin A in elderly women. All of the average plasma levels of antioxidant vitamins were within normal range. However the percentage of the elderly women with deficiency plus marginal values were 7.9% in vitamin C, 9.2% in vitamin A and 7.9% in vitamin E. Plasma levels of IL-2 and IL-6 were 27.1${\pm}$7.1pg/ml and 5.9${\pm}$5.3pg/ml in elderly women. Correlation data showed that plasma IL-2 level was negatively correlated with plasma vitamin C level. In addition, IL-6 level was also negatively correlated with plasma vitamin C, A and E levels, respectively. There was a significant positive correlation between erythrocyte thiobarbituric acid-reactive substance(TB-ARS) level and plasma IL-2 or IL-6 levels. In addition, erythrocyte TBARS level showed a significant positive correlation with plasma total antioxidant status (TAS) level and a significant negative correlation with plasma vitamin C level. Overall results might imply that the decreased levels of antioxidant vitamins result in an increase in oxidative stress and thereby increase cytokine production such as IL-2 and IL-6. However further research is required to elucidate these relationships.

• Journal of the Korean Society of Clothing and Textiles
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• v.2 no.1
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• pp.157-166
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• 1978

The purpose of this study was; (1) to examine ready-to-wear dresses to find the characteristics of labels and construction which existed at three different price levels and (2) to make the gathered information available to consumers, designers, manufacturers and the people who are concerned with ready-to-wear garments. A check sheet was made listing a wide variety of features which could cause garments to be different. For the statistical analysis. 87 dresses were used out of 116 dresses examined. Observation was made at the stores in Myung Dong, Suh-Dae Moon and No Ryang Jin in Seoul from February 16, 1978 to March 3, 1978. The findings are; 1. The average prices of high, medium and low priced levels were ${\\}54,728$, ${\\}41,448$ and ${\\}7,225$. The average price discrepancy between high and medium priced levels was ${\\}13,000$ and ${\\}34,194$ between medium and low priced levels. 2. Most of the dresses examined had labels in all three priced levels. The most informative labels were found on medium priced dresses and then high. The low priced dresses had no information which would be of help to the consumer in regard to care, size and Jiber content. 3. Most of the dresses examined were cut on lengthwise grain. The stitching of medium and high priced levels were satisfactory. The chief way of fastening threads at the end of stitching was by backtracking. $28\%$ of the low priced levels was found unappropriate in stitching number because it was too large to the fabric. Many dresses in low priced levels were not pressed well. The average hem width of low priced dresses were less than 3cm, the high 3-4cm and the medium 4-5cm. Hemming was done mostly by hand in high and medium and by machine in low priced dresses. The medium priced dresses used more linings than low and high priced dresses.

• Journal of Animal Science and Technology
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• v.61 no.6
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• pp.305-312
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• 2019

This study was carried out to investigate the effects of dietary energy levels on growth performance, blood parameter, and intestinal morphology of Pekin ducks in low temperature. A total of 500, 21-d-old Pekin ducks (initial BW = 1,089 ± 5.21 g) were evenly assigned to five dietary treatments (2,950, 3,000, 3,050, 3,100, or 3,150 kcal AME/kg, calculated on an as-is basis) with four replicates (pens) for each treatment (25 ducks per pen). During the experiment, hens were provided with feed and water ad libitum. Overall, increasing dietary energy levels corresponded to an increase of final body weight and body weight gain (linear, p < 0.01). Feed intake decreased (linear, p < 0.01) and feed conversion ratio increased (linear, p < 0.01) with increasing levels of energy. There were no significant differences (p < 0.05) in the level of leukocytes between groups. However, heterophils decreased (quadratic, p < 0.05) and lymphocytes increased (linear, p < 0.01) as inclusion of dietary energy levels increased. The H/L ratio increased (linear, p < 0.01) with increasing dietary energy levels while serum corticosterone levels decreased at overall experimental periods. Triglycerides increased (linear and quadratic, p < 0.05) with increasing dietary energy levels. There were no significant changes in villus height or crypt depth of the jejunum at overall experimental. In conclusion, increasing concentrations of dietary energy levels up to 2,950-3,150 kcal/kg in diet. Additionally, 3,150 kcal/kg dietary energy had been revealed more beneficial and could be practiced as protective management for the Pekin ducks reared under low ambient temperature (8℃ to 10℃).

• Journal of Nutrition and Health
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• v.31 no.9
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• pp.1385-1393
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• 1998

The hypoglycemic effects of butanol(BuOH) fraction of Polygonatum odoratum with vitamin E in streptozotocin(STZ)-induced diabetic rats were investigated. Sprague-Dawley rats weighing 200-230g were devided into five groups, and four groups induced diabetes mellitus by the STZ injection(45mg/kg b.w.) into the tail vein : Normal, diabetic-control, and three diabetic experimental groups(p. odoratum group, P. od-vit. E group and Vit. E group). All groups were fed on a AIN-76 diet, and the experimental groups were orally administered with the BuOH fraction of Polygonatum odoratum(500mg/kg b.w.) and vitamin E(10mg/kg b.w.) for 14 days. The body weight, diet intake and organ weights were monitored. The plasma levels of glucose, insulin, cholesterol, triglyceride, HDL-cholesterol and aspartate and alanine aminotransferase activities were analyzed. The levels of glycogen in liver and muscle, cholesterol in liver were determined. The malondialdehyde(MDA) levels in liver, kidney and lung were assayed. The body weight loss was seen in P. odoratum group, P. od-vit. E group, Vit. E group and diabetic control group, while the loss in P. odoratum group was much less than that in the diabetic control group. The plasma glucose levels were significantly lowered in P. odoratum group compared to diabetic control group. The plasma insulin levels were noticeably higher in P. odoratum and Vit. E groups. The rats in P. odoratum and P. od-vit. E group showed higher liver glycogen levels than in the diabetic control group. The MDA levels in liver, kidney and lung were also significantly reduced in P. od-vit. E and Vit. E groups compared to the diabetic control group. The results suggest that the administration of BuOH fraction of Polygonatum odoratum along with vitamin E reduced blood glucose levels and peroxidative tissue damage in STZ-induced diabetic rats, showing the possibility of preventive and therapeutic use of the wild edible plant to the diabetes mellitus. (Korean J Nutrition 31(9) : 1385-1393, 1998)

• IMMUNE NETWORK
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• v.2 no.4
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• pp.223-226
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• 2002

Background: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the serum levels of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-2 receptor, IL-10, IL-$1{\beta}$, IL-1 receptor antagonist and monocyte chemoattractant protein-1 (MCP-1) were reported to be higher in lepromatous leprosy. TNF-${\alpha}$ is also known to be higher in ENL, which is reduced after thalidomide treatment. However the serum type 2 chemokine levels in lepromatous leprosy patients have not been reported. Methods: The serum levels of the type 2 chemokines such as thymus and activation-regulated chemokine (TARC), macrophage-derived chemokine (MDC) and eotaxin together with IL-12 and IL-10 in the sera from leprosy patients were detected using an enzyme-linked solvent assay (ELISA) method. Results: The Serum TARC, MDC, eotaxin, IL-10 and IL-12 levels in lepromatous leprosy patients were not significantly different from the normal control levels. The serum levels were not significantly different between the paucibacillary group and multibacillary group. The serum TARC or MDC levels in the ENL patients were more reduced after a treatment containing thalidomide. Conclusion: The type 2 chemokines are not related to the severity of lepromatous leprosy. The larger reducing effect of the TARC or MDC levels in ENL patients by a treatment containing thalidomide suggests the potential role of these chemokines in the development of ENL and the therapeutic mechanism of thalidomide.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.4
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• pp.326-333
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• 2014

Internet Services have security issues. To prepare proper security measures for these security issues, security level setting is positively necessary. Until now, we use a security level with CIA (Confidentiality, Integrity, and Availability) Security Levels. However, CIA Security Levels has problems with ambiguous measures for the middle level of security setting. Moreover, security level overlap occurs, in some cases, when user authentications are not done. Additionally, there exist some levels among CIA Security Levels which cannot be applied to Internet services. In this paper, new security level model, CIAA Security Levels with deletion of ambiguous middle level of security setting and addition of authentication to one of security level setting factors, is proposed. The CIAA Security Levels model can be applied to more concrete security measures than CIA Security Levels. The proposed Security Levels model is applicable to almost any on-line services and it can be applied to new online services.

• Journal of Environmental Health Sciences
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• v.29 no.2
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• pp.38-44
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• 2003

This study was performed to investigate the levels of fluoride (F), calcium (Ca), and magnesium (Mg) in water samples taken from five reservoirs or direct sources on a stream used for agricultural or domestic water in the Iksan and Wanjoo areas, Jeon-buk, Korea, and to find a possible link between Ca or Mg and fluoride in water sources in theses areas. The samples were collected by the recommendation methods of the World Health Organization and analyzed by the recommendations of the Japanese Standard Methods. Statistical analyses were performed by the analysis of variance and correlation analysis. The F levels in water samples wire 0.80~2.53 ppm. In four sampling sites the water fluoride levels exceeded 1 ppm. which if the recommended level for fluorosis/caries control. The Ca levels in water samples were 6.82~12.98 ppm, and the Mg levels were 0.30~1.97 ppm, which are lower compared with the natural levels of water sources previously reported by other investigators. This study showed a positive correlation between Ca and Mg (r= 0.8779. p<0.01) and a negative correlation between F and Ca (r=-0.6974, p<0.05) and also between F and Mg (r=-0.5581) in the water samples. However, the study did not find remarkable relationships in fluoride levels between sampling sites. These results support the fact that there were epidemics of dental fluorosis in this area. The lack of significant positive correlations in fluoride levels between sampling sites suggests that there may be some pathways for the transfer of the metal to the water through other environmental media besides the water course. Long-term epidemiological studies are needed on the relationship between high F together with low Ca and Mg levels in the water, and total human health in this community. There should alto be a long-term monitoring of the water quality in this area.

• Clinical and Experimental Pediatrics
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• v.60 no.2
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• pp.45-49
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• 2017

Purpose: Serum level of 25-hydroxyvitamin D (25-OHD) is considered as the most appropriate marker of vitamin D status. However, only a few studies have investigated the relationship between 25-OHD and parathyroid hormone (PTH) in children. To this end, this study was aimed at evaluating the lowest 25-OHD level that suppresses the production of parathyroid hormone in children. Methods: A retrospective record review was performed for children aged 0.2 to 18 years (n=193; 106 boys and 87 girls) who underwent simultaneous measurements of serum 25-OHD and PTH levels between January 2010 and June 2014. Results: The inflection point of serum 25-OHD level for maximal suppression of PTH was at 18.0 ng/mL (95% confidence interval, 14.3-21.7 ng/mL). The median PTH level of the children with 25-OHD levels of <18.0 ng/mL was higher than that of children with 25-OHD levels ${\geq}$ 18.0 ng/mL (P<0.0001). The median calcium level of children with 25-OHD levels<18.0 ng/mL was lower than that of children with 25-OHD levels${\geq}18.0ng/mL$ (P=0.0001). The frequency of hyperparathyroidism was higher in the children with 25-OHD levels<18.0 ng/mL than in the children with 25-OHD levels${\geq}18.0ng/mL$ (P<0.0001). Hypocalcemia was more prevalent in the children with 25-OHD levels<18.0 ng/mL than in the children with 25-OHD levels${\geq}18.0ng/mL$ (P<0.0001). Conclusion: These data suggest that a vitamin D level of 18.0 ng/mL could be the criterion for 25-OHD deficiency in children at the inflection point of the maximal suppression of PTH.

• Korean journal of food and cookery science
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• v.7 no.2
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• pp.51-74
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• 1991

It has been many changes in traditional Korean food habits according to the improvement of household income levels and the rise of standard of living. Therefore, the pattern of consumption in animal origin processed/convenient foods would have changed. This research aims to find the tendency of consumption in some animal origin processed/convenient foods compared with typical Korean traditional foods according to household income levels. Therefore, this survey was made on 698 children from 10 elementary schools located in Seoul. They were divided into 6 groups according to their household income levels. The data were analysed using Chi-square test and F-test in SPSS package program. From this research, the following results were obtained: 1. Their average monthly household income levels were between 500, 000~1, 500, 000 won(64.2%) and their family were of mostly 4~5 members. There were no significant differences in children's physical status among various income groups. As the household. income level increases, the food expenditure per month increases and Engel's coefficient decreases. 2. The animal origin processed/convenient foods that have no significant differences are ham, sausage, milk, yogurt, canned fish, and fish meal. The high-income groups preferred bacon, cheese, pork cutlet, and fried chicken, compared to those of low-income groups. The low-income groups preferred crab-flavored meal, compared to those of high-income groups. 3. In some Korean traditional foods, there were significant differences according to income levels. Those were Bulgogi, baked fish, fried meat, cooked fish and meat with soy-bean sauce. Fried fish and anchovy have no significant differences in food intake frequency according to household income levels. Chicken and egg saute are liked by children in every income groups. 4. Between the animal origin processed/convenient foods and the typical Korean nonprocessed traditional foods, children preferred the former regardless of income levels. In conclusion, animal origin processed/convenient food consumption patterns were not affected by household income levels.