• 제목/요약/키워드: Level Shift

검색결과 892건 처리시간 0.029초

Effect of Estrogen on the Gestational Profiles in Gene Expression of Placental Lactogen I, II and Pit-i in the Rat Placenta (흰쥐 태반에서 Placental Lactogen I과 II 그리고 Pit-1의 유전자 발현에 미치는 에스트로겐의 영향)

  • 정진권;강성구;강해묵;이병주
    • The Korean Journal of Zoology
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    • 제39권1호
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    • pp.115-121
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    • 1996
  • To investigate gestational profiles in gene expression of placental lactogen I fpL4), PL-lI and Pit-1, RNA samples were extracted from the placentas of pregnant day 12 to 20 at 2 day intervals. Northern blots showed changes in gene expression of PL4, - 11 and Pit-i. Sizes of PL-l and -II mRNA were changed and amounts of PL-I, -H and Pit-1 mRNA increased during progress of gestation. To examine the effect of estrogen on the gene expression of PL-I, -Il and Pit-1, pregnant female rats were ovariectomized (OVX) and daily injected with estradiol (OVX + E). OVX markedly lowered the amount of PL4 and 41 mRNA, and shifted niRNA size from 1 kb to i 3 kb in PL-l mRNA and 0.6 kb to i kb in PL-ll mRNA, respectively. OVX had no effect on the mRNA size of Pit-1, but markedly attenuated Pit-1 mRNA level. Estrogen injection reversed the effect of OVX on the size-shift but not on the amount of PL4 and -Il mRNA. Replacement of E partially recovered OVX-induced inhibition of Pit-i mRNA level. Present results suggest that estrogen may play a pivotal role on the gene expression of PL-l and -Il such as alternative RNA splicing and/or polyadenylation, and Pit-1 may be involved in the gene expression of PL-l and 41 by estrogen.

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A Study on the Design of Green Mode Power Switch IC (그린 모드 파워 스위치 IC 설계에 관한 연구)

  • Lee, Woo-Ram;Son, Sang-Hee;Chung, Won-Sup
    • Journal of IKEEE
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    • 제14권2호
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    • pp.1-8
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    • 2010
  • In this paper, Green Mode Power IC is designed to reduce the standby power. The proposed and designed IC works for the Switch Mode Power Supply(SMPS) and has the function of PWM. To reduce the unnecessary electric power, burst mode and skip mode section are introduced and controlled by external power MOSFET to diminish the standby power. The proposed IC is designed and simulated by KEC 30V-High Voltage 0.5um CMOS Process. The structure of proposed IC is composed of voltage regulator circuit, voltage reference circuit, UVLO(Under Voltage Lock out) circuit, Ibias circuit, green circuit, PWM circuit, OSC circuit, protection circuit, control circuit, and level & driver circuit. Measuring the current consumption of each block from the simulation results, 1.2942 mA of the summing consumption current from each block is calculated and ot proved that it is within the our design target of 1.3 mA. The current consumption of the proposed IC in this paper is less than a half of conventional ICs, and power consumption is reduced to the extent of 1W in standby mode. From the above results, we know that efficiency of proposed IC is superior to the previous IC.

The use of Intravenous Albumin for the Prevention of Ovarian Hyperstimulation Syndrome in Patients at High Risk in in Vitro Fertilization (과배란유도에 의한 난소과자극증후군 발생 고위험군에 있어서 알부민 정맥투여요법의 효과에 관한 연구)

  • Moon, Shin-Yong;Roh, Jae-Sook;Lee, Kyung-Soon;Suh, Chang-Suk;Kim, Seok-Hyun;Choi, Young-Min;Shin, Chang-Jae;Kim, Jung-Gu;Lee, Jin-Yong;Chang, Yoon-Seok
    • Clinical and Experimental Reproductive Medicine
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    • 제22권2호
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    • pp.171-181
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    • 1995
  • Ovarian hyperstimulation syndrome(OHSS) is one of the well-known complication of controlled ovarian hyperstimulation(COH). Though there have been numerous measures to prevent the occurrence of OHS, it has not been completely preventable until now. The fluid shift from the intravascular space to the third space is due to decreased oncotic pressure of the serum. The objective of this study was to evaluate if IV administration of 20% albumin in those patients with OHSS risk can make prevention of severe OHSS. We retrospectively analysed 70 patients undergoing IVF-ET who had serum peak estradiol($E_2$) level of >2,500 pg/ml and/or the number of oocytes retrieved over 20. The treatment group(n=39) received albumin while the control group(n=31) did not. After 40 grams of human albumin diluted in 1,000 ml of 0.9% sodium chloride solution, the treatment group received half of the fluid during oocyte retrieval, the remainder in the recovery suite. The results were as follows; There were significant differences in the levels of serum peak $E_2$ and number of oocytes retrieved between the two groups(p<0.05). However, there were no significant differences in the incidence of OHSS and pregnancy rate or multifetal pregnancy rate. In conclusion, administration of albumin to OHSS risk patients did not reduce the rate of OHSS in IVF-ET. However, if we consider the fact that there were differences in the level of peak serum $E_2$ and oocyte numbers, further prospective study may be needed.

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A Study on the Differences in Self-perceived Oral Health Levels in Workers at Seoul-Inchon Area (경인지역 근로자의 자기평가 구강건강수준 인식에 관한 연구)

  • Kim, Sook-Hyang;Hong, Min-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • 제12권12호
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    • pp.5692-5699
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    • 2011
  • This study aims to determine potential differences in self-perceived oral health levels between blue-collar and white-collar workers. It is based upon questionnaire survey data dating from Mar. 1 to 30, 2011. All the data collected from 200 blue-collar workers and 100 white-collar worker was analyzed using statistical tools like SPSS ver. 19.0. Self-perceived oral health levels were analysed across three sub-factors - physical, psycho-social, and psychological factors - which were confirmed through factor analysis. The psycho-social factor was statistically significant for age and shift work. Self-perceived oral health levels across the three factors were quantitatively correlated except for psychological factors in blue-collar workers. The study found that occupational group affects workers' self-perceived oral health level. The explanatory power of these 4 variables total 51% in blue-collar group. In case of white-collar group, it was found one variable total 30%. Since oral health levels differ between blue-collar and white-collar workers, oral health promotion projects should differentiate between the two groups, and workers with an interest in their tooth for the prevention, yet negligent act because it will keep your personal oral health care in the prevention-oriented oral health promotion.

Analysis of Positive Bias Temperature Instability Characteristic for Nano-scale NMOSFETs with La-incorporated High-k/metal Gate Stacks (La이 혼입된 고유전체/메탈 게이트가 적용된 나노 스케일 NMOSFET에서의 PBTI 신뢰성의 특성 분석)

  • Kwon, Hyuk-Min;Han, In-Shik;Park, Sang-Uk;Bok, Jung-Deuk;Jung, Yi-Jung;Kwak, Ho-Young;Kwon, Sung-Kyu;Jang, Jae-Hyung;Go, Sung-Yong;Lee, Weon-Mook;Lee, Hi-Deok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • 제24권3호
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    • pp.182-187
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    • 2011
  • In this paper, PBTI characteristics of NMOSFETs with La incorporated HfSiON and HfON are compared in detail. The charge trapping model shows that threshold voltage shift (${\Delta}V_{\mathrm{T}}$) of NMOSFETs with HfLaON is greater than that of HfLaSiON. PBTI lifetime of HfLaSiON is also greater than that of HfLaON by about 2~3 orders of magnitude. Therefore, high charge trapping rate of HfLaON can be explained by higher trap density than HfLaSiON. The different de-trapping behavior under recovery stress can be explained by the stable energy for U-trap model, which is related to trap energy level at zero electric field in high-k dielectric. The trap energy level of two devices at zero electric field, which is extracted using Frenkel-poole emission model, is 1,658 eV for HfLaSiON and 1,730 eV for HfLaON, respectively. Moreover, the optical phonon energy of HfLaON extracted from the thermally activated gate current is greater than that of HfLaSiON.

Analysis of the Threshold Voltage Instability of Bottom-Gated ZnO TFTs with Low-Frequency Noise Measurements (Low-Frequency Noise 측정을 통한 Bottom-Gated ZnO TFT의 문턱전압 불안정성 연구)

  • Jeong, Kwang-Seok;Kim, Young-Su;Park, Jeong-Gyu;Yang, Seung-Dong;Kim, Yu-Mi;Yun, Ho-Jin;Han, In-Shik;Lee, Hi-Deok;Lee, Ga-Won
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • 제23권7호
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    • pp.545-549
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    • 2010
  • Low-frequency noise (1/f noise) has been measured in order to analyze the Vth instability of ZnO TFTs having two different active layer thicknesses of 40 nm and 80 nm. Under electrical stress, it was found that the TFTs with the active layer thickness of 80 nm shows smaller threshold voltage shift (${\Delta}V_{th}$) than those with thickness of 40 nm. However the ${\Delta}V_{th}$ is completely relaxed after the removal of DC stress. In order to investigate the cause of this threshold voltage instability, we accomplished the 1/f noise measurement and found that ZnO TFTs exposed the mobility fluctuation properties, in which the noise level increases as the gate bias rises and the normalized drain current noise level($S_{ID}/{I_D}^2$) of the active layer of thickness 80 nm is smaller than that of active layer thickness of thickness 40 nm. This result means that the 80 nm thickness TFTs have a smaller density of traps. This result correlated with the physical characteristics analysis performmed using XRD, which indicated that the grain size increases when the active layer thickness is made thicker. Consequently, the number of preexisting traps in the device increases with decreasing thickness of the active layer and are related closely to the $V_{th}$ instability under electrical stress.

Effects of Precursor Concentration on Surface and Optical Properties of ZnO Nano-Fibrous Thin Films Fabricated by Spin-Coating Method (스핀코팅 방법으로 제작된 ZnO 나노 섬유질 박막의 전구체 농도에 따른 표면 및 광학적 특성)

  • Kim, Min-Su;Kim, Ghun-Sik;Yim, Kwang-Gug;Cho, Min-Young;Jeon, Su-Min;Choi, Hyun-Young;Lee, Dong-Yul;Kim, Jin-Soo;Kim, Jong-Su;Lee, Joo-In;Leem, Jae-Young
    • Journal of the Korean Vacuum Society
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    • 제19권6호
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    • pp.483-488
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    • 2010
  • ZnO nano-fibrous thin films with various precursor concentrations ranging from 0.2 to 1.0 mol (M) were grown by spin-coating method and effects of the precursor concentration on surface and optical properties of the ZnO nano-ribrous thin films were investigated by using scanning electron microscopy (SEM) and photoluminescence (PL). ZnO nuclei were formed at the precursor concentration below 0.4 M and the ZnO nano-fibrous thin films were grown at the precursor concentration above 0.6 M. Further increase in the precursor concentration, the thickness of the ZnO nano-fibrous thin films is gradually increased. The intensity and the full-width at half-maximum (FWHM) of the near-band-edge emission (NBE) is increased as the precursor concentration is increased. The deep-level emission (DLE) is red-shifted as the precursor concentration is increased.

The Changes of Vitamin C Content in Yulmoo Mulkimchi According to the Shift of Fermentation Temperature (발효 온도의 변화에 따른 열무 물김치 중 비타민 C의 함량 변화)

  • 최성유;한영숙
    • Korean journal of food and cookery science
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    • 제13권3호
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    • pp.364-368
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    • 1997
  • The vitamin C contents in Mulkimchi (watery kimchi prepared with Yulmoo, leaf radish) were analyzed during its fermentation and storage at 30$^{\circ}C$, 15$^{\circ}C$ and 4$^{\circ}C$, respectively. The total amount of vit. C in Mulkimchi fermented for 1 day at 30$^{\circ}C$ was rapidly increased to the highest level of 20 mg%. At this time, Mulkimchi showed pH 4.5 and 0.2% of total acidity expressed in lactic acid. The total microbes of the kimchi amounted to 10$\^$8/ cfu/$m\ell$ which are mostly found to be lactic acid bacteria. However, the amount of vitamin C in Mulkimchi was decreased gradually during the storage at 30$^{\circ}C$, 15$^{\circ}C$ and 4$^{\circ}C$ for 9 days. In the Mulkimchi fermentated at 15$^{\circ}C$, the maximum amount of vitamin C was 15 mg% at 4 to 5 day-fermentation. The pH of this kimchi was 4.0 and its acidity was 0.15% as lactic acid. When the storage temperature was dropped to 4$^{\circ}C$ after 1 day-fermentation at 15$^{\circ}C$, its vitamin C didn't reach the above level after 9 day storage. As the fermentation temperature was kept at 4$^{\circ}C$, the content of vitamin C in Mulkimchi remained at 10 mg% of its initial storage and didn't change through the 9 days storage.

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A Study on the Development of SSB Modem (디지털 SSB 모뎀 개발에 관한 연구)

  • Kim, Jeong-Nyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • 제11권10호
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    • pp.1852-1857
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    • 2007
  • The SSB modem performs the modulation process which converts the digital voltage level to the audible frequency band signal and the demodulation process which converts reversely the audible frequency signal to the digital voltage level. The modulator and the demodulator are implemented with a single DSP chip. Because of the SSB specific character, the distortion occurs when the frequency is changed. This distortion has no effect on voice communication but it has an significant effect on data communication. In other words, it is impossible to send data stream with adjacent 2 periods. Therefore, in case of using 2-tone FSK, it is needed to send at least 3 periods to transmit 1 bit. Therefore we implemented the modem using modified phase-delay shift keying to transmit 1 tone signal for high speed transmission. In the 1200[bps] mode, it generates 0, $187{\mu}s$, delay time at 1.3kHz symbol frequency, and in the 2400[bps] mode, 0, $70{\mu}s\;130{\mu}s\;200{\mu}s$, delay time at 1.5kHz symbol frequency. Finally, in the maximum 3600[bps] mode, it generates 0, $100{\mu}s\;160{\mu}s\;250{\mu}s$ 2.0kHz symbol frequency. The measured results of the implemented SSB modem shows a good transfer functional characteristic by spectrum analyzer, almost same bandwidth in pass band and 20dB higher SNR comparing the emu FACTOR and American CLOVER and in the experimental transmitting test, we verified the transmitted data is received correctly in platform.

A Comparative Study on Outbreak Scale of Cochlodinium polykrikoides Blooms (Cochlodinium polykrikoides 적조발생규모에 대한 비교연구)

  • Kang, Yang-Soon;Park, Young-Tae;Lim, Weol-Ae;Cho, Eun-Seob;Lee, Chang-Kyu;Kang, Young-Shil
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • 제14권4호
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    • pp.229-239
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    • 2009
  • To understand major factors that affected on distinct Cochlodinium bloom scale in Korean coasts in 2007 and 2008, oceanographic and meteorological characteristics during Cochlodinium bloom period were compared. The main reason for large scale blooms in 2007, covering both southern coast and eastern coast with about 10 million US dollars fish kills, was attributed to sufficient nutrient supply by heavy rainfall, upwelling in the coast arising from irregular wind shift, weak thermocline and low grazing pressure by zooplanktons during Cochlodimum bloom development period. On the contrary, small scale blooms in 2008 covering only inshore areas of southern coast without fish kills was attributed to the low nutrient level in coastal areas by long persistent drought and strong influence of oligotrophic offshore water onto inshore and high grazing pressure by extra ordinarily abundant zooplanktons during Cochlodinium development period. Conclusively, it was estimated that nutrient level, strength of offshore water and feeding pressure might play a significant role in the difference of bloom scale between the two years.