• Title/Summary/Keyword: Left-sided

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Evaluation of the heart and lung dosimetric parameters in deep inspiration breath hold using 3D Slicer

  • Eskandari, Azam;Nasseri, Shahrokh;Gholamhosseinian, Hamid;Hosseini, Sare;Farzaneh, Mohammad Javad Keikhai;Keramati, Alireza;Naji, Maryam;Rostami, Atefeh;Momennezhad, Mehdi
    • Radiation Oncology Journal
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    • v.38 no.1
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    • pp.68-76
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    • 2020
  • Purpose: The present study was conducted to compare dosimetric parameters for the heart and left lung between free breathing (FB) and deep inspiration breath hold (DIBH) and determine the most important potential factors associated with increasing the lung dose for left-sided breast radiotherapy using image analysis with 3D Slicer software. Materials and Methods: Computed tomography-simulation scans in FB and DIBH were obtained from 17 patients with left-sided breast cancer. After contouring, three-dimensional conformal plans were generated for them. The prescribed dose was 50 Gy to the clinical target volume. In addition to the dosimetric parameters, the irradiated volumes and both displacement magnitudes and vectors for the heart and left lung were assessed using 3D Slicer software. Results: The average of the heart mean dose (Dmean) decreased from 5.97 to 3.83 Gy and V25 from 7.60% to 3.29% using DIBH (p < 0.001). Furthermore, the average of Dmean for the left lung was changed from 8.67 to 8.95 Gy (p = 0.389) and V20 from 14.84% to 15.44% (p = 0.387). Both of the absolute and relative irradiated heart volumes decreased from 42.12 to 15.82 mL and 8.16% to 3.17%, respectively (p < 0.001); however, these parameters for the left lung increased from 124.32 to 223.27 mL (p < 0.001) and 13.33% to 13.99% (p = 0.350). In addition, the average of heart and left lung displacement magnitudes were calculated at 7.32 and 20.91 mm, respectively. Conclusion: The DIBH is an effective technique in the reduction of the heart dose for tangentially treated left sided-breast cancer patients, without a detrimental effect on the left lung.

Bandwidth selection for discontinuity point estimation in density (확률밀도함수의 불연속점 추정을 위한 띠폭 선택)

  • Huh, Jib
    • Journal of the Korean Data and Information Science Society
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    • v.23 no.1
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    • pp.79-87
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    • 2012
  • In the case that the probability density function has a discontinuity point, Huh (2002) estimated the location and jump size of the discontinuity point based on the difference between the right and left kernel density estimators using the one-sided kernel function. In this paper, we consider the cross-validation, made by the right and left maximum likelihood cross-validations, for the bandwidth selection in order to estimate the location and jump size of the discontinuity point. This method is motivated by the one-sided cross-validation of Hart and Yi (1998). The finite sample performance is illustrated by simulated example.

ON INJECTIVITY AND P-INJECTIVITY

  • Xiao Guangshi;Tong Wenting
    • Bulletin of the Korean Mathematical Society
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    • v.43 no.2
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    • pp.299-307
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    • 2006
  • The following results ale extended from P-injective rings to AP-injective rings: (1) R is left self-injective regular if and only if R is a right (resp. left) AP-injective ring such that for every finitely generated left R-module M, $_R(M/Z(M))$ is projective, where Z(M) is the left singular submodule of $_{R}M$; (2) if R is a left nonsingular left AP-injective ring such that every maximal left ideal of R is either injective or a two-sided ideal of R, then R is either left self-injective regular or strongly regular. In addition, we answer a question of Roger Yue Chi Ming [13] in the positive. Let R be a ring whose every simple singular left R-module is Y J-injective. If R is a right MI-ring whose every essential right ideal is an essential left ideal, then R is a left and right self-injective regular, left and right V-ring of bounded index.

ON ENDOMORPHISM RING OF H-INVARIANT MODULES

  • Bae, Soon-Sook
    • East Asian mathematical journal
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    • v.6 no.2
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    • pp.167-182
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    • 1990
  • The relationships between submodules of a module and ideals of the endomorphism ring of a module had been studied in [1]. For a submodule L of a moudle M, the set $I^L$ of all endomorphisms whose images are contained in L is a left ideal of the endomorphism ring End (M) and for a submodule N of M, the set $I_N$ of all endomorphisms whose kernels contain N is a right ideal of End (M). In this paper, author defines an H-invariant module and proves that every submodule of an H-invariant module is the image and kernel of unique endomorphisms. Every ideal $I^L(I_N)$ of the endomorphism ring End(M) when M is H-invariant is a left (respectively, right) principal ideal of End(M). From the above results, if a module M is H-invariant then each left, right, or both sided ideal I of End(M) is an intersection of a left, right, or both sided principal ideal and I itself appropriately. If M is an H-invariant module then the ACC on the set of all left ideals of type $I^L$ implies the ACC on M. Also if the set of all right ideals of type $I^L$ has DCC, then H-invariant module M satisfies ACC. If the set of all left ideals of type $I^L$ satisfies DCC, then H-invariant module M satisfies DCC. If the set of all right ideals of type $I_N$ satisfies ACC then H-invariant module M satisfies DCC. Therefore for an H-invariant module M, if the endomorphism ring End(M) is left Noetherian, then M satisfies ACC. And if End(M) is right Noetherian then M satisfies DCC. For an H-invariant module M, if End(M) is left Artinian then M satisfies DCC. Also if End(M) is right Artinian then M satisfies ACC.

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Comparison of Dosimetrical and Radiobiological Parameters on Three VMAT Techniques for Left-Sided Breast Cancer

  • Kang, Seong-Hee;Chung, Jin-Beom;Kim, Kyung-Hyeon;Kang, Sang-Won;Eom, Keun-Yong;Song, Changhoon;Kim, In-Ah;Kim, Jae-Sung
    • Progress in Medical Physics
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    • v.30 no.1
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    • pp.7-13
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    • 2019
  • Purpose: To compare the dosimetrical and radiobiological parameters among various volumetric modulated arc therapy (VMAT) techniques using restricted and continuous arc beams for left-sided breast cancer. Materials and Methods: Ten patients with left-sided breast cancer without regional nodes were retrospectively selected and prescribed the dose of 42.6 Gy in 16 fractions on the planning target volume (PTV). For each patient, three plans were generated using the $Eclipse^{TM}$ system (Varian Medical System, Palo Alto, CA) with one partial arc 1pVMAT, two partial arcs 2pVMAT, and two tangential arcs 2tVMAT. All plans were calculated through anisotropic analytic algorithm and photon optimizer with 6 MV photon beam of $VitalBEAM^{TM}$. The same dose objectives for each plan were used to achieve a fair comparison during optimization. Results: For PTV, dosimetrical parameters such as Homogeneity index, conformity index, and conformal number were superior in 2pVMAT than those in both techniques. $V_{95%}$, which indicates PTV coverage, was 91.86%, 96.60%, and 96.65% for 1pVMAT, 2pVMAT, and 2tVMAT, respectively. In most organs at risk (OARs), 2pVMAT significantly reduced the delivered doses compared with the other techniques, excluding the doses to contralateral lung. For the analysis of radiobiological parameters, a significant difference in normal tissue complication probability was observed in ipsilateral lung while no difference was observed in the other OARs. Conclusions: Our study showed that 2pVMAT had better plan quality and normal tissue sparing than 1pVMAT and 2tVMAT but not for all parameters. Therefore, 2pVMAT could be considered the priority choice for the treatment planning for left breast cancer.

A Surgical Experience of Adult TOF with Anomalous Systemic Venous Return (체정맥 이상환류를 동반한 성인 활로씨 4증후군의 치험 1례)

  • 유환국
    • Journal of Chest Surgery
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    • v.24 no.11
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    • pp.1154-1159
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    • 1991
  • Anomalous systemic venous return to the right atrium is clinically innocuous and cause no functional disturbances or physiologic abnormalities by themselves and consequently require no treatment but may be surgical importance. We experienced a case of adult TOF combined with anomalous systemic venous drainage. Rudimentary right SVC with draining left sided vertical vein and IVC with separately drained left vein was revealed at operation time. With the bicaval cannulation, large sucker was used for drainage of blood from the left hepatic vein. Postoperative angiocardiogram showed above findings and combined double inferior vena cava at lumbar level.

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Congenital Esophageal Hiatal Hernia in a Cat (고양이에서의 선천성 식도열공허니아 1예)

  • 정성목;정언승;김순영;최성천;손혜정;이충호;양정환;김완희;서민호
    • Journal of Veterinary Clinics
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    • v.18 no.1
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    • pp.61-64
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    • 2001
  • A 1.2 kg, five-month-old, female domestic short-hair cat was referred to Seoul National University Veterinary Medical Teaching Hospital with a history of vomiting immediatley after eating. Clinical signs were depression, anorexia, severe dehydration and vomiting since weaning. According to history taking, physical examination, complete blood count, serum chemical profile and contrast radiographic study, it was diagnosed as congenital sliding esophageal hiatal hernia. Diaphragmatic plication, esophagopexy and left-sided belt-loop gastropexy were performed. Ranitidine (2 mg/kg, IV, q12h) and sucralfate suspension (20 mg/kg, PO, q6h) were administered with low-fat liquified diet to treat reflux esophagitis. Clinical signs related to esophageal hiatal hernia disappeared immediately after surgical treatment and did not recur for 4 months.

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Double Aortic Arch with Right Sided Descending Aorta - Report of 1 case - (우측 하행 대동맥을 동반한 중복 대동맥궁 - 1례 수술 치험 -)

  • 조경수
    • Journal of Chest Surgery
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    • v.23 no.1
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    • pp.201-204
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    • 1990
  • The double aortic arch is the commonest anomaly among the vascular rings are relatively rare congenital vascular anomalies. This anomaly is malformation of the aortic arch system may, by compression of the trachea and esophagus, cause respiratory distress and dysphagia. We experienced one case of double aortic arch with right sided descending aorta with predominant right anterior arch treated surgically at Kyung Hee University Medical Center. 1-year-old male patient with acute airway obstruction due to combination of double aortic arch and right descending aorta. The diagnosis was made by simple X-ray & confirmed by barium esophagogram & aortogram. The operative approach was through left thoracotomy & underwent division of the left aortic arch & division of ligamentum arteriosum & suspension of divided proximal end of anterior arch to anterior thoracic wall. The postoperative courses was uneventful and doing well on the 3 years.

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Right-sided heart failure in congenital heart diseases (선천성 심질환에서 우심부전)

  • Jung, Jo Won
    • Clinical and Experimental Pediatrics
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    • v.50 no.11
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    • pp.1055-1060
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    • 2007
  • Right-sided heart failure is a major problem among patients with congenital heart diseases, due to the prevalence of congenital heart defects and the association of pulmonary hypertension. More attention is focused on the structure of the right heart particularly in association with congenital heart defects and chronic lung disease. The right ventricle (RV) may support the pulmonary circulation, and sometimes the systemic circulation (systemic RV) in congenital heart defects. Despite major progress being made, assessing the RV remains challenging, often requiring a multi-imaging approach and expertise (echocardiography, magnetic resonance imaging, nuclear and cineangiography). Evidence is accumulating that RV dysfunction develops in many of these patients and leads to considerable morbidity and mortality. While there is extensive literature on the pathophysiology and treatment of left heart failure, the data for right-sided heart failure is scarce. Therefore RV function in certain groups of congenital heart disease patients needs close surveillance and timely and appropriate intervention to optimise outcomes. An understanding of RV physiology and hemodynamics will lead to a better understanding of current and future treatment strategies for right heart failure. This will review right-sided heart failure with the implications of volume and pressure loading of the RV in congenital heart diseases.