• Title/Summary/Keyword: Lee Sam

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Hepatoprotective Effect of Manual Acupuncture at Sam-hwang Points on $CCl_4$-induced Liver Damage in Rats ($CCl_4$로 유발된 흰쥐의 간손상에 대한 삼황혈(三黃穴) 수기침자극(手技鍼刺戟)의 간기능 보호효과)

  • Lee, Hyun;Hong, Kwon-Eui;Kim, Young-Il;Kim, Tae-Han;Choi, Hak-Joo;Kim, Sun-Jin;Yim, Yun-Kyoung
    • Korean Journal of Acupuncture
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    • v.22 no.1
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    • pp.109-116
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    • 2005
  • Objectives : To investigate the hepatoprotective effect of manual acupuncture at Sam-hwang points on hepatotoxicity in $CCl_4$-intoxicated rats. Methods : Rats were injected intraperitoneally with $CCl_4$(1ml/kg) and treated with manual acupuncture at left Sam-hwang points 3 times a week for 10 weeks. A non-acupoint in left Gluteal area was selected as a sham point. Acupuncture was performed by an experienced acupuncture doctor using tonifying manipulation technique. To estimate the effects on hepatotoxici쇼, body weight and liver weight of rats were measured, and biochemical assays(ALT, AST, ALP, Total cholesterol, etc.) and blood cell analysis were performed. Results : Manual acupuncture with tonifying technique at Sam-hwang points reduced liver weight, ALT, AST, ALP activities and total cholesterol in serum significantly compared with control group. In blood cell analysis, WBC and lymphocytes were reduced but neutrophil was increased by manual acupuncture at Sam-hwang points in rats. Conclusions : Manual acupuncture with tonifying technique at Sam-hwang points has an hepatoprotective effect on $CCl_4$-induced liver damage in rats.

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Electrochemical Properties and Fabrication of Conjugated System Conducting Oligomer Self-assembled Monolayer (공액구조 전도성 올리고머 자기조립단분자막의 제작 및 전기화학적 특성)

  • Min, Hyun Sik;Lee, Tae Yeon;Oh, Se Young
    • Applied Chemistry for Engineering
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    • v.22 no.5
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    • pp.545-550
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    • 2011
  • We have synthesized a high electrically conductive 4-(2-(4-(acetylthio)phenyl)ethynyl)benzoic acid (APBA) with a conjugated aromatic structure as a bio fix linker, and then fabricated APBA self-assembled monolayer (SAM) with a self-assembly technique. The structure of the prepared APBA SAM was studied and electrochemical properties of APBA SAM immobilized with a ferrocene molecule were investigated. Also, we have examined the molecular orientation and oxidation-reduction redox characteristics of the mixed SAM consisting of APBA and butanethiol (BT) with a X-ray photo electron spectroscopy (XPS) and cyclicvoltammetry, respectively. Electrochemical activity of the mixed SAM was increased with increasing the mixed time. Especially, the maximum redox current was obtained at a mixed time of 36 hrs.

Mixed H2/H infinity FIR Fitters for Discrete-time State Space Models

  • Lee, Young-Sam;Kwon, Wook-Hyun;Han, Soo-Hee
    • 제어로봇시스템학회:학술대회논문집
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    • 2002.10a
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    • pp.52.1-52
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    • 2002
  • Young Sam Lee : He is currently a PhD candidate student. His research interest includes time-delay systems, signal processing, and receding horizon control. Wook Hyun Kwon : His research interest includes time-delay systems, signal processing, receding horizon control, and robust control. He is the president of IFAC 2008 which is to be held in Korea. Soo Hee Han : He is currently a PhD candidate student. His research interest includes time-delay systems, signal processing, receding horizon control, and communication.

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Development and Standardization of Modified Self-Assessment Manikin for Emotional Valence and Arousal Manikin (정서가 및 각성수준에 대한 자가 평가 마네킹 척도개발 및 표준화)

  • Kang, Eun-Ho;Choi, Jeong-Eun;Ham, Byung-Joo;Seok, Jeong-Ho;Lee, Kyoung-Uk;Kim, Won;Lee, Seung-Hwan;Lim, Hyun-Kook;Park, Young-Min;Yang, Jong-Chul;Ahn, Meekyung;Lee, Jae Seon;Chae, Jeong-Ho
    • Anxiety and mood
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    • v.7 no.2
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    • pp.113-118
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    • 2011
  • Objectives : The Self-Assessment Manikin (SAM) developed by Bradley and Lang is a non-verbal pictorial assessment tool that measures human emotion and has been widely used. However, the pictures in SAM have not been easy for Korean subjects to understand or relate to. The authors developed a new manikin (Emotional Valence and Arousal Manikin, EVAS) modeling it after Korean faces while modifying and standardizing the SAM. Methods : Forty-one healthy subjects participated in this study. They were asked to rate the emotional valence and level of arousal using both the SAM and EVAS after being exposed to pictures of facial expressions for affective neurosciences-Korean version. The internal consistency of the EVAS and the correlation between EVAS and SAM were examined. Resuts : Internal consistencies of the valence using the EVAS were from 0.63 (surprise) to 0.82 (happiness) and those of the arousal were from 0.90 to 0.95. Correlation coefficients of the valence and arousal between the SAM and EVAS were from 0.61 (both surprise and disgust) to 0.84 (neutral) and from 0.82 (sadness) to 0.94 (fear), respectively. Conclusions : We developed a new manikin (the EVAS) for the Korean population modifying and standardizing the SAM. The EVAS demonstrated a good internal consistency and validity. As such, it can be used in the field of human emotion research.

Effects of Hap-Kok(LI4) and Jok-Sam-Lee(ST36) Acupuncture on Cerebral Blood Flow in In-Young(ST9) (합곡(合谷) 및 족삼이(足三里) 혈(穴) 자침이 인영혈(人迎穴)부위의 뇌혈류에 미치는 영향)

  • Lee, Chung-Sik;Park, Bo-Ra;Seo, Jong-Hoon;Kang, Hyung-Won;Lyu, Yeoung-Su;Kim, Tae-Heon
    • Journal of Oriental Neuropsychiatry
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    • v.18 no.1
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    • pp.143-151
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    • 2007
  • Objective : This study was performed to evaluate the effects of Hap-Kok(LI4) and Jok-Sam-Lee(ST36) acupuncture on blood flow in In-Young(ST9). Method : Monitoring of TCD was examined in each 25's healthy men and wemen in 20s before and after acupucture on both(right and left) Hap-kok(LI4) and was done on both(right and left) Jok-Sam-Lee(ST36) by different group with same condition. Mean velocity and Pulsatility index analyzed from TCD at both In-Young(ST9). Both group was acupuctured for 15-20 minutes laying at bed. Results : The results showed a significant($p{\le}0.05:$ Paired T-test) decrease in mean velocity and increase in pulsatility index at both group. Conclusion : These results suggest that acupuncture could have a specific effect on blood flow called In-Young acupoint.

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The effects of Sam-chool-gun-bi-tang administration on urine metabolic responses during carbohydrate loading diet to long distance runners (탄수화물 부하식이요법시 삼출건비탕(蔘出健脾湯) 투여가 시합 전·후 장거리 달리기 선수의 뇨중 대사 성분 변화에 미치는 영향)

  • Han, Young-Gyu;Lee, Myeong-Jong
    • The Journal of Dong Guk Oriental Medicine
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    • v.8 no.2
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    • pp.83-96
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    • 2000
  • Objective This experimental study was designed to investigate effects of Sam-chool-gun-bi-tang administration during carbohydrate loading diet to long distance runners on changes of the urine metabolic responses. Materials and Methods All subjects were divided randomly with two groups, Sam-chool-gun- bi-tang administration Group (N=5) and control group (N=5) and attended on domestic marathon race. The urine samples were collected by 15ml conical tube at rest, a day before race, immediately after race, a day after race. These samples were used to analyze for the factors of the change on metabolic responses. At First, the factors of the routine urine test were checked; RBC, WBC, glucose, protein, ketone, bilirubin, urobilirubin. Next, the factors on the changes of the electrolyte metabolism and creatinine were checked; $Na^+ $, $Cl^-$, $K^+$, $Ca^{+ +}$, Creatinine. Results 1. Urine RBC, WBC, glucose, protein, ketone, bilirubin, urobilirubin were all denoted negatively (-). 2. Urine pH response in Sam-chool-gun-bi-tang administration group was shown significant difference between two groups at immediately after race. 3. Urine $Na^+$ response in Sam-chool-gun- bi-tang administration group was shown significant difference between two groups at immediately after race. 4. Urine $K^+$ response in Sam-chool-gun-bi-tang administration group was shown significant difference between two groups at immediately after race and a day after race. 5. Urine $Cl^-$ response in Sam-chool-gun- bi-tang administration group was increased at immediately after race, but was not shown significant difference between two groups. 6. Urine $Ca^{+ +}$ response in Sam-chool-gun-bi-tang administration group was decreased gradually, but was not shown significant difference between two groups. 7. Urine Creatinine response in Control group was decreased significantly at immediately after race, but was not shown significant difference between two groups. Conclusion According to the above results, it was shown that Sam-chool-gun- bi-tang administration had the positive effects on changes of the urine matabolic responses during carbohydrate loading diet to the long distance runners.

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A Design of Management and Verification Tool of Component and A Development of SAM Simulator based on Dynamic Reconfiguration Architecture (컴포넌트 관리 및 검증도구 설계와 동적 재구성 아키텍처 기반 SAM 시뮬레이터 개발)

  • Suk, Jeebeom;Lee, Jaeoh;Lee, Jaejin;Seo, Yoonho
    • Journal of the Korea Society for Simulation
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    • v.22 no.2
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    • pp.1-10
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    • 2013
  • Modeling and simulation techniques construct experimental environment considering battlefields and are able to analyze performance of components of weapon system that closely resemble reality. However, developed model has low scalability and not cared reusability because it has been used only in a limited range of domain. In this paper, we develop a verification tool to verify reusability of developed component for dynamic reconfiguration and to judge scalability of it and a management tool to control data of it effectively. In addition, dynamic reconfiguration architecture of guided weapon systems designed in the previous study has been applied to SAM(Surface to Air Missile) System Simulator, and we study effectiveness of the developed component. Thus the user can configure various guided weapon systems through simulation application of dynamic reconfiguration architecture of component.