• Title/Summary/Keyword: Lee Sam

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Analysis of Beam Hardening of Modulation Layers for Dual Energy Cone-beam CT (에너지 변조 필터로 구현한 이중 에너지 콘빔 CT의 에너지 스펙트럼 평가 연구)

  • Ahn, Sohyun;Cho, Sam Ju;Keum, Ki Chang;Choi, Sang Gyu;Lee, Rena
    • Progress in Medical Physics
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    • v.27 no.1
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    • pp.8-13
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    • 2016
  • Dual energy cone-beam CT can distinguish two materials with different atomic compositions. The principle of dual energy cone-beam CT based on modulation layer is that higher energy spectrum can be acquired at blocked x-ray window. To evaluate the possibility of modulation layer based dual energy cone-beam CT, we analyzed x-ray spectrum for various thicknesses of modulation layers by Monte Carlo simulation. To compare with the results of simulation, the experiment was performed on prototype cone-beam CT for 50~100 kVp with CdTe XR-100T detector. As the result of comparing, the mean energy of energy spectrum for 80 kVp are well matched with that of simulation. The mean energy of energy spectrum for 80 and 120 kVp were increased as 1.67 and 1.52 times by 2.0 mm modulation layer, respectively. We realized that the virtual dual energy x-ray source can be generated by modulation layer.

Studies on Erythropoietin Bioassay Method (Erythropoietin 검사법(檢査法)에 관(關)한 연구(硏究))

  • Cho, Kyoung-Sam;Ro, Heung-Kyu;Lee, Mun-Ho
    • The Korean Journal of Nuclear Medicine
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    • v.9 no.2
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    • pp.39-46
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    • 1975
  • It is the purpose of this paper to design the most preferable method of erythropoietin bioassay in Korea. Bioassay utilizing polycythemic mice are currently in general use for the indirect determination of erythropoietin. Assay animals are usually prepared either by transfusion or by exposure to reduced oxygen tension in specially constructed chamber. We prepared the polycythemic, mice by the specially constructed hypobaric chamber. We observed weights and hematocrits of the mice in the hypobaric chamber, then hematocrits and 72 hours $^{59}Fe$ red cell upatke ratio of the polycythemic mice induced by hypoxia after removal from the hypobaric chamber. We designed the method of erythropoietin bioassay according to the results obtained by above experiments. Then we measured the 72 hours $^{59}Fe$ red cell uptake ratio of the polycythemic mice with normal saline, normal plasma and anemic plasma according to the method we designed. The results are followed: 1. The hematocrits of the mice in hypobaric chamber increased to 74% in 14 days It is preferable to maintain the pressure of the chamber to 400mmHg for first 4 days then 300mmHg for last 10 days to reduce the death rate and time consuming in hypobaric chamber. 2. After removal from the hypobaric chamber, the 72 hours $^{59}Fe$ red cell uptake ratio decreased rapidly and maintained the lowest level from the fourth day to tenth day. 3. We design the method of erythropoietin bioassay according to the results of above experiment and to the half life of erythropoietin. 4. The Korean product S9Fe is mixture of $^{59}Fe\;and\;^{55}Fe$. And the $^{59}Fe$ red cell uptake ratio in normal mice was far less with Korean product $^{59}Fe$ than with pure $^{59}Fe$ of foreign product. So it is desirable to use pure $^{59}Fe$ in this method of erythropoietin bioassay. 5. Considering the cost, the technique, the time consuming and the sensitivity it is the most preferable method of erythropoietin bioassay in Korea using hypobaric chamber to induce the polycythemia.

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Prediction of Ground Subsidence Hazard Area Using GIS and Probability Model near Abandoned Underground Coal Mine (GIS 및 확률모델을 이용한 폐탄광 지역의 지반침하 위험 예측)

  • Choi, Jong-Kuk;Kim, Ki-Dong;Lee, Sa-Ro;Kim, Il-Soo;Won, Joong-Sun
    • Economic and Environmental Geology
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    • v.40 no.3 s.184
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    • pp.295-306
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    • 2007
  • In this study, we predicted areas vulnerable to ground subsidence near abandoned underground coal mine at Sam-cheok City in Korea using a probability (frequency ratio) model with Geographic Information System (GIS). To extract the factors related to ground subsidence, a spatial database was constructed from a topographical map, geo-logical map, mining tunnel map, land characteristic map, and borehole data on the study area including subsidence sites surveyed in 2000. Eight major factors were extracted from the spatial analysis and the probability analysis of the surveyed ground subsidence sites. We have calculated the decision coefficient ($R^2$) to find out the relationship between eight factors and the occurrence of ground subsidence. The frequency ratio model was applied to deter-mine each factor's relative rating, then the ratings were overlaid for ground subsidence hazard mapping. The ground subsidence hazard map was then verified and compared with the surveyed ground subsidence sites. The results of verification showed high accuracy of 96.05% between the predicted hazard map and the actual ground subsidence sites. Therefore, the quantitative analysis of ground subsidence near abandoned underground coal mine would be possible with a frequency ratio model and a GIS.

Evaluation of Feed Value of Barley Fodder as an Alternative Feed Ingredient

  • Kim, Tae-Il;Mayakrishnan, Vijayakumar;Lim, Dong-Hyun;Lee, Hyun-Jeong;Son, Jun-Kyu;Kim, Yoon-Jeong;Choi, Hee-Chul;Shin, Jae-Hyeong;Park, Jong-Ho;Kim, Sam-Churl;Ki, Kwang-Seok
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.40 no.3
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    • pp.161-166
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    • 2020
  • Barley is an important cereal gain which is traditionally used in some nations of Asia and North Africa, and there has been growing interest in using barley as an ingredient in food due to their nutritional value and high content of phyto-constituents. However, no study report on comparative feed value between sprouted barley, cornflake and alfalfa hay. Therefore, in this study we aimed to evaluate the chemical composition, amino acid profile and mineral content of 6 day sprouted barley fodder (SBF) compared with cornflake and alfalfa hay using by AOAC method, as an alternative feed ingredient. Results showed that SBF had higher content of crude protein, acid detergent insoluble crude proteins and neutral detergent insoluble crude protein than alfalfa hay and cornflake; cornflake had higher crude fiber, neutral detergent fiber content than SBF and alfalfa hay; alfalfa hay had higher crude fiber, crude ash, acid detergent fiber, neutral detergent fiber and lignin level than SBF and cornflake. Also, significant differences were found on amino acid content among them (p<0.01). The most abundant amino acid in SBF was glutamate (123 g/kg DM), which is higher than in alfalfa hay (1.27%) or cornflake (1.58%). However, methionine (1.33%) and cysteine (1.53%) were the least abundant amino acids in SBF compared with cornflake or alfalfa hay. Furthermore, our study results exhibited that SBE comprise a good sources of minerals including ferrous (90.01 mg/kg) followed by zinc (20.50 mg/kg), magnesium (0.20 mg/kg) and sodium (0.03 mg/kg) as compared to cornflake and alfalfa hay. The present research findings, confirmed that the nutritional values of SBF are comparable to those of cornflake and alfalfa hay. Hence, SBF can be a better alternative feed ingredient for cornflake or alfalfa hay. However, feeding trials will be required to determine acceptability of SBF for ruminant production.

Changes in the Quality Characteristics of Muskmelon Treated with Different Concentrations of 1-MCP During Storage (1-Methylcyclopropene(1-MCP) 처리농도에 따른 머스크멜론(Cucumis melo L.)의 품질특성 변화)

  • Kim, Ji-Young;Lee, Hye-Ok;Yoon, Doo-Hyun;Cha, Hwan-Soo;Do, Jeong-Ryong;Kim, Byeong-Sam
    • Korean Journal of Food Science and Technology
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    • v.42 no.3
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    • pp.368-372
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    • 2010
  • Changes in the quality characteristics of muskmelon were analyzed by treating samples with 500, 1,000, and 1,500 ppb 1-MCP every 4 days and then storing the samples at $10^{\circ}C$. The weight losses of the MCP treated samples were lower than those of the control, while there were no differences in the concentrations among treatments. The firmness was maintained at a higher value in 1-MCP treated samples than the control during the storage period and showed the highest value in the 1,000 ppb treatment. The L-values (brightness of samples) in the 500 and 1,000 ppb treatments were kept constant during the storage period, while that of the control showed a decreasing trend after four days of storage. The bvalues and yellowness, were decreased after showing an increasing trend in both treatments and the control as the storage period passed. The respiration rates of 1-MCP treated samples were lower than the control, with the lowest value being observed in the 1,000 ppb treatment. The texture observed upon sensory evaluation was higher and freshness was maintained longer in the 1,000 ppb treatment. Therefore, 1,000 ppb 1-MCP was considered to be the most effective concentration for treatment of muskmelon.

A Study on Low-Temperature Oxidation Reactivity of Pt/ZrO2·SO42-Catalyst (ZrO2·SO42-에 담지된 백금촉매의 저온산화반응성에 대한 연구)

  • Kim, Kiseok;Lee, Tae Jung;Kim, Byoung Sam;Kim, Du Soung
    • Applied Chemistry for Engineering
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    • v.9 no.1
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    • pp.141-148
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    • 1998
  • Reactivity of Pt catalysts(0.2, 0.5 wt% Pt) supported on solid super acid, $ZrO_2$ $SO_4{^{2-}}$ for low-temperature oxidation was investigated for complete oxidation of cyclohexane. Catalytic activity measured as reactant conversion in a packed-bed tubular reactor increased in accordance with the acidity and specific surface area of the catalyst activity and specific surface area of $Pt/ZrO_2$ $SO_4{^{2-}}$ catalyst were diminished by adding potassium during catalyst preparation. the catalyst activity decreased in accordance with the amount of potassium added. In addition, $Pt/ZrO_2$ $SO_4{^{2-}}$ catalyst exhibited an activity greater than that of a $Pt/SiO_2$ or $Pt/Al_2O_3$ catalyst possessing much larger specific surface area at $250^{\circ}C$ for the reactant stream of 15.000 ppm cyclohexane concentration and $18,000hr^{-1}$ space velocity, a cyclohexane conversion as high as 96% was obtained over 0.2 wt% $Pt/ZrO_2$ $SO_4{^{2-}}$, whereas cyclohexane conversions over 0.2 wt% $Pt/SiO_2$ and 0.2 wt% $Pt/Al_2O_3$ were 83 and 79%, respectively.

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Phylogenetic position of five Korean strains of Alexandrium tamarense(Dinophyceae), based on internal transcribed spacers ITS1 and ITS2 including nuclear-encoded 5.85 rRNA gene sequences (ITS 부위에 근거한 한국산 Alexandrium tamarense 5 클론의 계통분류학적 위치)

  • Cho, Eun-Seob;Lee, Sam-Geun;Kim, Ik-Soo
    • Journal of Life Science
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    • v.12 no.6
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    • pp.821-834
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    • 2002
  • In order to measure the inter- and intraspecific genetic divergences within the genus Alexandrium, the variations within the internal transcribed spacer (ITS1 and ITS2) regions and 5.85 ribosomal RNA gene of eight Alexandrium species were examined for 33 strains from diverse geographical locations by direct sequencing. Five isolates of A. tamarense (AT-2, AT-6, AT-10, AT-A and AT-B) from Jinhae Bay, Korea were found to be completely identical to a Japanese strain OFX151-A. The length of the amplified ITSI-5.85-ITS2 region varied from 481 nucleotides (in A. margalefi) to 528 nucleotides (in A. affine CU1-1). ITS1 and ITS2 nucleotide lengths were negatively correlated, whereas a positive correlation was found between their G+C content. The degree of sequence divergence ranged from 0.3% (1 bp) to a maximum of 53% (305 Up). Pairwise sequence comparisons revealed a small degree of divergence between A. tamarense and A. Pundyense isolates (1.2 - 2.3% = 6-12 bp), but a high degree of divergence between A. tamarense and A. catenella (19.8% = 102 bp), and between A. catenella and A. Pundyense (19.7%). Although most nodes were weakly supported by bootstrap values, some types tend to form independent molecular groups. A. catenella isolates also formed an independent molecular sub-group, with relaticula strong bootstrap values (94% or 85% and 79% or 98%, respectively in PAUP and NJ trees). Interestingly, A. cohorticula and A. frateculus always clustered within the same sub-group, this result being supported by strong bootstrap values. Our results indicate that the ITS regions provide useful informations on hierarchical population genetic structure and a high phylogenetic resolution in intraspecific and interspecific Alexandrium population.

Effect of Submerged Culture of Ceriporia lacerata Mycelium on Insulin Signaling Pathway in 3T3-L1 Cell (Ceriporia lacerata 균사체 배양물이 3T3-L1 세포에서 인슐린 신호 전달에 미치는 영향)

  • Shin, Eun Ji;Kim, Ji-Eun;Kim, Ji-Hye;Park, Yong Man;Yoon, Sung Kyoon;Jang, Byeong-Churl;Lee, Sam-Pin;Kim, Byoung-Cheon
    • Journal of Life Science
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    • v.26 no.3
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    • pp.325-330
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    • 2016
  • In this study, we evaluated the antidiabetic effect of submerged culture of Ceriporia lacerata mycelium (CL01) on glucose uptake and the expression of mRNA and protein of major signal markers of insulin signaling pathway in 3T3-L1 adipocytes. After 3T3-L1 adipocytes were pre-treated by CL01 (0, 2, 10 mg/ml) for 8 hours, followed with treatment of insulin, the glucose uptake levels significantly increased by more 55.1%, 94.4% than negative control respectively (p<0.01, 0.001) in a dose-dependent manner. However, in case of CL01 pre-treatment without insulin, the glucose uptake did not increase compared with insulin-treated 3T3-L1. Also we demonstrated that the protein expression levels of pIR β, pAkt, pPI3K and pAMPK and the mRNA expression levels of GLUT4 in adipocytes inducing insulin resistance increased in CL01-treated group compared with negative control. These results demonstrated that CL01 affected glucose metabolism and the protein and gene expression through insulin signaling pathway, and increased glucose uptake levels effectively. More than 90% of those who have suffered for type 2 diabetes are more likely to have from hyperinsulinemia, hypertension, obesity and etc. because of altered insulin signaling pathway. So, it is probably considered that intake of CL01 may treat type 2 diabetes by normalization of insulin signaling pathway, and it will provide useful evidences regarding a mechanism for cure of type 2 diabetes.

Effects of Ruminally Inserted Artificial Fiber on Growth Performance, Feed Intake and Carcass Characteristics of Hanwoo Steers (반추위내 인공섬유질 투여가 거세한우의 발육, 사료섭취량 및 도체특성에 미치는 영향)

  • Cho, Young-Moo;Park, Byung-Ki;Kwon, Eung-Gi;Lee, Wang-Shik;Choe, Chang-Yong;Son, Sam-Kyu;Hong, Seong-Koo
    • Journal of Animal Science and Technology
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    • v.51 no.3
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    • pp.225-230
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    • 2009
  • This experiment was carried out to investigate the effects of ruminally inserted artificial fiber (RIAF; polymerized fibrous implements) on growth performance, feed intake and carcass characteristics of Hanwoo steers. Thirty six steers averaging $368.3\pm20.3kg$ were randomly assigned into three groups: control group, the ruminal insertion of three pieces (T1), and five pieces (T2) of RIAF. Average daily gain, feed intakes and conversions among treatments were similar. Numbers of rumen villi were higher in RIAF treatment (T1 and T2) groups than control group, but they were not significant (p>0.05). The length of villi were significantly longer in T2 than control group (p<0.05). Fecal weight tended to decrease in T1 compared with the control group (p>0.05). There was no differences on carcass traits inc1uding longissmus muscle area, back fat thickness, marbling score, meat color, and fat color among treatments.

Effects of Change of Body Weight on Racing Time in Thoroughbred Racehorses (더러브렛 경주마의 체중변화가 주파기록에 미치는 효과)

  • Cho, Kwang-Hyun;Son, Sam-Kyu;Cho, Byung-Wook;Lee, Hak-Kyo;Kong, Hong-Sik;Jeon, Gwang-Joo;Park, Kyung-Do
    • Journal of Animal Science and Technology
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    • v.50 no.6
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    • pp.741-746
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    • 2008
  • The objective of this study was to estimate the effects of change in body weight on racing time in Thoroughbred racehorses, using total 8,197 horses and 155,656 racing records collected from Korea Racing Association(KRA). The average body weight of the racehorses was 449kg, and the average body weights of stallion, gelding and mare were 460kg, 454kg and 441kg, respectively. Body weight of stallion was the greatest. The considerable loss of body weight was observed in March, April and May for mare, and in May, Jun and July for stallion and gelding. Overall, the body weight of the racehorses decreased in spring and summer, and increased in autumn and winter. The estimated heritability and repeatability for racing time were 0.237 and 0.525, respectively. The heritability for body weight estimated from total records was 0.612. The estimated heri- tabilities for body weight were 0.472, 0.578 and 0.555 for gelding, stallion and mare, respectively. As the change of body weight was greater than ±10kg, the racing time increased significantly. When the body weight changed more than ±20kg in comparison to the changes of body weight of ±5kg, the racing time increased by 0.3 second. When the change of body weight was ±0.5% of body weight, the racing time was the best(fastest). When the change of body weight was more than ±2.5%, racing performance decreased considerably.