• Physical Therapy Rehabilitation Science
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• v.10 no.3
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• pp.278-288
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• 2021

Objective: The purpose of this study is to investigate the effect of stabilization exercise on whole-body vibration on pain, dysfunction, psychosocial factors, balance ability, and abdominal contraction with patients with low back pain. Design: A randomized controlled trial Methods: A total of 34 patients with low back pain were assigned randomly to experimental group (n=17) and control group (n=17). Both groups underwent a neuromuscular stabilization exercise program. In addition, the experimental group implemented the neuromuscular stabilization exercise program using whole-body vibration. All interventions were applied 60 min per session, 3 times per week for total 4 weeks. Numeric Rating Scale (NRS), Korean version of Oswestry Disability Index (K-ODI), Fear-Avoidance Beliefs Questionnaire (FABQ), balance ability, muscle thickness and contraction ratio were compared to evaluate the effect on intervention. Results: Both groups showed significant differences in NRS, balance ability, and muscle thickness in contraction, contraction ratio before and after intervention (p<0.05). In addition, the experimental group showed significant difference in the amount of change in NRS, balance ability and muscle thickness in contraction, contraction ratio values than the control group (p<0.05). Conclusions: Neuromuscular stabilization exercise program combined with whole-body vibration stimulation has been proven to be an effective and clinically useful method to decrease pain, dysfunction, increase balance ablilty, and transverse abdominis muscle thickness in contraction and contraction ratio for patients with low back pain.

• International Journal of Oral Biology
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• v.46 no.3
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• pp.146-153
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• 2021

Accurate identification of microbes facilitates the prediction, prevention, and treatment of human diseases. To increase the accuracy of microbiome data analysis, a long region of the 16S rRNA is commonly sequenced via paired-end sequencing. In paired-end sequencing, a sufficient length of overlapping region is required for effective joining of the reads, and high-quality sequencing reads are needed at the overlapping region. Trimming sequences at the reads distal to a point where sequencing quality drops below a specific threshold enhance the joining process. In this study, we examined the effect of trimming conditions on the number of reads that remained after quality control and chimera removal in the Illumina paired-end reads of the V3-V4 hypervariable region. We also examined the alpha diversity and taxa assigned by each trimming condition. Optimum quality trimming increased the number of good reads and assigned more number of operational taxonomy units. The pre-analysis trimming step has a great influence on further microbiome analysis, and optimized trimming conditions should be applied for Divisive Amplicon Denoising Algorithm 2 analysis in QIIME2 platform.

• Physical Therapy Rehabilitation Science
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• v.9 no.4
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• pp.281-286
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• 2020

Objective: This study examined the effects of dynamic tape applied to the patellofemoral joint on the knee valgus angle, muscle activity, and ground reaction force during a single leg squat (SLS) and single leg landing (SLL). Design: Cross-sectional study. Methods: Twenty-four subjects (11 male, 13 female) who met the inclusion criteria were screened by the knee palpation and patella compression tests. First, the knee valgus angle and muscle activity during SLS were measured. Second, the knee valgus angle and ground reaction force during SLL were measured. For the intervention, a patella joint loop using dynamic tape was used. The knee valgus angle, muscle activities in SLS and SLL after the intervention, and the ground reaction force were measured in the same way. A paired t-test was used to examine the difference between before and after the intervention. Results: The knee valgus angle showed a statistically significant improvement after dynamic taping application in SLS and SLL (p<0.05). The differences in muscle activity of the VL/VMO and ground reaction forces were not statistically significant after dynamic taping application in SLS and SLL. Conclusions: This study showed that dynamic taping applied around the patellofemoral joint was effective in improving the knee valgus angle in SLS and SLL and had a reduced risk of secondary injury during sports activity.

• Physical Therapy Rehabilitation Science
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• v.10 no.4
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• pp.406-413
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• 2021

Objective: The purpose of this study was to investigate effects of taping technique applied to knee instability. Design: Cross sectional study. Methods: Twenty-six participants with knee instabilityparticipated in this study. They were randomly assigned to the Kinesio taping (KT) group (n=13) and the dynamic taping (DT) group (n=13). Both groups applied knee stabilization taping techniques. In order to compare the effects of each taping technique, the change in the landing error scoring system (LESS) and lower extremity joint angle wasrecorded before and after the intervention. Results: Both groups significantly decreased in the change before and after the LESS (p<0.05). At the joint angle of the lower extremities, KT group significantly reduced the valgus angle at the max knee flexion (p<0.05). In DT group knee joint flexion and hip joint flexion angles were significantly increased at foot contact (p<0.05). In max knee flexion, the knee joint flexion angle was significantly increased (p<0.05). In foot contact, max knee flexion, the knee joint valgus angle was significantly increased (p<0.05). DT group showed more significant changes in knee joint flexion angle at foot contact and hip joint flexion angle at max knee flexion. Conclusions: Dynamic taping is a clinically applicable intervention method for lowering the risk of non-contact injury in participants with knee instability and for knee stability during rehabilitation exercises.

• Publications of The Korean Astronomical Society
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• v.33 no.3
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• pp.31-44
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• 2018

Song, I-Yeong (1619 ~ ?) was an active astronomer in the Joseon dynasty at the era of adopting the Shixian-li, Chinese calendar in Qing dynasty. His astronomical contribution was recorded in Annals of the Joseon Dynasty, Diary of the Royal Secretariat, Comparative Review of Records and Documents-Its Revision and Enlargement, and Treatise on the Bureau of Astronomy. In addition the details on his life and works were found at the genealogies of the Song Family from Yeonan and the Kim Family from Seonsan. His major astronomical activities can be summarized in three items. First, as a specialist astronomer, he has attempted to make a systematic observation of two comets. Second, he designed and fabricated the Jamyeong-jong, the weight-powered armillary clock, which became a typical model of the astronomical clock in the Joseon dynasty. Last, he served as a royal astronomical professor, greatly contributing on implementing the Shixian-li. Song has concentrated on performing astronomical duties for his royal official service time. Song is regarded as an important astronomer who made it possible to enforce the Shixian-li until the late Joseon dynasty.

• Journal of Powder Materials
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• v.26 no.4
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• pp.311-318
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• 2019

The objective of this study is to investigate the influence of powder shape and densification mechanism on the microstructure and mechanical properties of Ti-6Al-4V components. BE powders are uniaxially and isostatically pressed, and PA ones are injection molded because of their high strengths. The isostatically compacted samples exhibit a density of 80%, which is higher than those of other samples, because hydrostatic compression can lead to higher strain hardening. Owing to the higher green density, the density of BE-CS (97%) is found to be as high as that of other samples (BE-DS (95%) and P-S (94%)). Furthermore, we have found that BE powders can be consolidated by sintering densification and chemical homogenization, whereas PA ones can be consolidated only by simple densification. After sintering, BE-CS and P-S are hot isostatically pressed and BE-DS is hot forged to remove residual pores in the sintered samples. Apparent microstructural evolution is not observed in BE-CSH and P-SH. Moreover, BE-DSF exhibits significantly fine grains and high density of low-angle grain boundaries. Thus, these microstructures provide Ti-6Al-4V components with enhanced mechanical properties (tensile strength of 1179 MPa).

• Journal of Industrial Convergence
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• v.1 no.2
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• pp.141-172
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• 2003

To enhance Social Welfare and Public Interests, government has been enforcing the policies that induce private Sector to participate in the Public Service. In general, these policies consist of the direct or indirect supporting systems, including the advantages of taxation applicable to Private Sector that takes part in Public Service. Of the various supporting systems taken by government, the privilege from the taxes is known to the most important supporting system. The representative exemple is the tax beduction of amounts donated to the not-for-profit organizations. That is to say that donations can be deductible from taxable amounts on assessing inheritance tax and gift tax. Generally much higher cumulative tax rates are applied to the laws of inheritance tax and gift tax than the other taxes in order to redistribute the social wealth and to restrain the concentration of the wealth. On the other hand, the special exemption from the taxes can be applied to not-for-profit organization according to the standards of the relevant lows and regulations, because not-for-profit organization usually performs the partial role of government in Public Service. The perpose of this study is to find the systematical support that the not-for-profit organizations can practice Public service more efficiently than government. This study approaches the subject by means of examining current taxation systems of inheritance tax law and gift tax law and developing systematic alternatives that can make inefficient parts in taxation systems more reasonable.

• International Journal of Industrial Entomology and Biomaterials
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• v.37 no.2
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• pp.100-104
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• 2018

The rearing of black soldier flies in Korea is affected by seasonal factors such as temperature and sun light; for this reason, it requires a great deal of effort to rear and maintain black soldier flies during the winter. In this study, we investigated how starvation affects larval development. After hatching the larvae, they were fed for 5 or 10 d and then starved for a certain period to see how they recovered. The length and width of larvae were estimated to be 18.18 to 21.96 mm, 5.19 to 6.04 mm, respectively. Larvae survivorship to the pupal stage was significantly different between groups and periods of starvation. The groups of fed for 5 d then starved showed a high survival rate until 20 d starvation and then the survival of larvae rapidly decreased. The survival rate of the larvae was abruptly decreased for 20 d starvation in the groups of fed for 10 d and starved, and then gradually decreased until 60 d starvation thereafter. Our research attempted to influence larvae development through starvation and provides basic information on how to culture the black soldier fly effectively and economically throughout the year.

• Molecules and Cells
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• v.42 no.2
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• pp.104-112
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• 2019

Tracking the fate of individual cells and their progeny through lineage tracing has been widely used to investigate various biological processes including embryonic development, homeostatic tissue turnover, and stem cell function in regeneration and disease. Conventional lineage tracing involves the marking of cells either with dyes or nucleoside analogues or genetic marking with fluorescent and/or colorimetric protein reporters. Both are imaging-based approaches that have played a crucial role in the field of developmental biology as well as adult stem cell biology. However, imaging-based lineage tracing approaches are limited by their scalability and the lack of molecular information underlying fate transitions. Recently, computational biology approaches have been combined with diverse tracing methods to overcome these limitations and so provide high-order scalability and a wealth of molecular information. In this review, we will introduce such novel computational methods, starting from single-cell RNA sequencing-based lineage analysis to DNA barcoding or genetic scar analysis. These novel approaches are complementary to conventional imaging-based approaches and enable us to study the lineage relationships of numerous cell types during vertebrate, and in particular human, development and disease.

• Molecules and Cells
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• v.42 no.3
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• pp.210-217
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• 2019

The maintenance of mitochondrial function is closely linked to the control of senescence. In our previous study, we uncovered a novel mechanism in which senescence amelioration in normal aging cells is mediated by the recovered mitochondrial function upon Ataxia telangiectasia mutated (ATM) inhibition. However, it remains elusive whether this mechanism is also applicable to senescence amelioration in accelerated aging cells. In this study, we examined the role of ATM inhibition on mitochondrial function in Hutchinson-Gilford progeria syndrome (HGPS) and Werner syndrome (WS) cells. We found that ATM inhibition induced mitochondrial functional recovery accompanied by metabolic reprogramming, which has been known to be a prerequisite for senescence alleviation in normal aging cells. Indeed, the induced mitochondrial metabolic reprogramming was coupled with senescence amelioration in accelerated aging cells. Furthermore, the therapeutic effect via ATM inhibition was observed in HGPS as evidenced by reduced progerin accumulation with concomitant decrease of abnormal nuclear morphology. Taken together, our data indicate that the mitochondrial functional recovery by ATM inhibition might represent a promising strategy to ameliorate the accelerated aging phenotypes and to treat age-related disease.