• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.11a
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• pp.230-230
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• 2007

전력선 통신(Power Line Communication)은 최근 전력선을 이용한 통신기술의 발달과 더불어 세계적으로 관심도가 높아지고 연구 개발 및 자본 투자가 활발히 진행되고 있으며, 안정적인 네트워크를 구성하기 위해서는 고주파 전력선 통신 신호를 차단하는 블로킹 필터가 반드시 적용되어야 한다. 전력선 통신용 블로킹 필터는 광대역의 주파수 특성과 높은 신호감쇄 특성 및 대전류 특성이 요구되며, 이러한 특성을 구현하기 위해서는 블로킹 필터의 핵심부품인 자심재료의 고투자율 및 대전류화가 이루어져야 한다. 따라서 본 연구에서는 우수한 전 자기적 특성이 균일하게 유지되고, 전력선에 흐르는 대전류에 의한 자심재료의 포화가 발생하지 않도륵 새로운 자심 재료를 설계하여, 전력선 통신을 적용한 홈 네트워크 구축의 핵심 부품인 광대역 블로킹 필터를 개발하고자 하였다. 2350과 0.3 T의 투자율과 포화자속 밀도를 갖는 EI 형상의 자심재료를 해석모델로 설정하고 다중 에어 갭의 위치에 따른 전류와 자속밀도 변화를 유한요소 해석법으로 분석한 결과 자심재료의 대전류 특성에 지배적인 영향을 미치는 에어 캡의 삽입 위치를 알 수 있었고, 새로운 해석 모델인 I 형상의 로드(ROD) 코어에 대해 수치해석을 수행하여, 100A의 통전 전류에서도 자기적으로 포화되지 않고 인덕턴스의 정밀 제어가 가능하고, 특성의 신뢰성과 대전류에 대한 안정성을 증가시킬 수 있는 인덕터를 설계하였다. 또한 수동소자를 이용한 LC 공진회로를 기본 구성으로 하고, 주파수 대역, 신호 감쇄율과 대전류 특성, 상용화를 고려하여 블로킹 필터 회로를 설계하였으며, 유한요소해석법을 적용한 전자장 모의해석을 통하여 최소의 크기를 갖는 I 형상의 자심재료에 $6{\Phi}$의 에나멜 동선을 6.5턴, 6턴 권선하여 2.5, $2.15\;{\mu}H$의 인덕턴스를 갖는 직렬 인덕터를 구현하였고 블로킹 필터를 구성하였다. 주파수에 따른 신호감쇄 특성을 5 Hz~1 MHz의 주파수 범위에서 측정한 결과 약 490 kHz~450 kHz의 주파수 대역에서 -70dB의 신호감쇄 특성을 나타냈다. 본 연구를 통해 개발된 100A급 광대역 블로킹 필터가 적용되어 상용화 될 수 있을 것으로 판단되며, 또한 모뎀 통신 주파수 대역에서 -70dB 이상의 높은 감쇄 특성을 갖기 때문에 신호차단 특성이 보다 우수할 것으로 사료된다.

• Journal of fish pathology
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• v.26 no.3
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• pp.193-206
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• 2013

The ark shell, Scapharca broughtonii is a marine bivalve mollusks belonging to the family Arcidae and important seafood for Korean and Japanese, and southern coast is brisk bays for the ark shell aquaculture. However, productivity of ark shell from these regions were rapidly reduced during the last decade due to mass mortality. The reason of this great damage has not yet been identified. To overcome this economic loss, diverse investigations were focused on environmental factors that affects in the physiology of S. broughtonii, but microbiological researches were performed insufficiently. Hemoglobin is one of the major blood component of ark shell and is damaged by some species of bacterial toxins. We concentrated on this red pigment because hemolysis could be the cause of ark shell mortality. In this study, we analyzed microbial diversity of underwater sediments in coastal regions and also existences in the body of S. broughtonii. We investigate about 4,200 isolates collected from June to September for microbial diversity of sediments and ark shell. We screened all of culturable microorganisms, and identified 25 genera 118 species, 24 genera 89 species, 30 genera 109 species and 39 genera 141 species, and selected 140 unique colonies for identification and challenge assay.

• Journal of Embryo Transfer
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• v.32 no.3
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• pp.87-94
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• 2017

Tissue engineering (TE) has been developed to create functional organs and tissue by combining 3D matrix and cells in vitro. Vascularization and angiogenesis are utmost important for supply of nutrients and oxygen in tissue engineered organs. The present study was performed to isolate and characterize primary endothelial cells (EC) from aorta of alpha 1, 3-enzyme galactosyltransferase knock out (GalT KO) pig, to minimize immune rejection and analyze body immune system for future xenotransplantation studies. Isolation of primary EC from aorta were performed by incubation with dispase for 8-10 min at $37^{\circ}C$. Primary EC were cultured in EC growth medium on different extra cellular matrix (ECM), either collagen or gelation. Primary EC exhibits morphological characteristics and showed positive expressions of EC specific marker proteins i.e. PECAM1, KDR and VWF despite of their ECM surface; however, on collagen based surface they showed increase in mRNA level analyzed by qPCR. Primary EC cultured on collagen were sorted by flow cytometer using KDR marker and cultured as KDR positive cells and KDR negative cells, respectively. KDR positive cells showed dramatically increased in PECAM1 and VWF level as compared to KDR negative cells. Based on the above results, primary EC derived from GalT KO are successfully isolated and survived continuously in culture without becoming overgrown by fibroblast. Therefore, they can be utilize for xeno organ transfer, tissue engineering, and immune rejection study in future.

• Journal of Chitin and Chitosan
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• v.23 no.4
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• pp.262-266
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• 2018

Even though the saps have been consumed as beverage in Korea, however a little research has been conducted on the chemical composition. We determined free sugars, mineral in the sap from Juglans mandshurica Maxim. collected from BongHwa region. The contents of glucose, sucrose, and fructose in the sap from J. mandshurica were 0.15, 2.73, and 0.09%, respectively. The prominent minerals in the sap from J. mandshurica were calcium and potassium. The contents of Ca, K, Mg, Fe, and Mn of sap from J. mandshurica were 0.61, 0.57, 0.12, 0.002, and 0.014 ppm, respectively. The sap from J. mandshurica show inhibitory effect on elastase. And real-time RT-PCR showed that sap from J. mandshurica increased mRNA level of AQP3 and HAS2 gene and increased hyaluronic acid production in HaCaT cells. These results indicated that the sap from J. mandshurica can potentially be used for developing cosmetic ingredient for skin moisturizing and anti-aging.

• Asian Journal of Turfgrass Science
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• v.20 no.2
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• pp.175-190
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• 2006

The term mycoherbicide started in 1970, but its interest heightened due to increase costs of chemical herbicides. A classical biocontrol agent is expected to become a permanent part of its new environment and do no harm to it. Contemporary biological control agent(BCA) must be produced by artificial culture and could be applied like chemical herbicides over weeds. BCA is different from the classical approach in that it released through natural spread. To date 26 species of fungi are used as classical BCA against 26 species of weeds in seven countries. There are a number of examples of pathogens attacking non-target plants. But through risk assessments which include understanding the taxonomy, biology and ecology, the target and non-target species, it will be safe to introduce of exotic pathogens to control weeds. But pathogens have not been successfully used in practice. Many mycoherbicides show potential in laboratories, but are ineffective in the field and not consistent from year to year or field to field. There is also a lack of understanding humidity, dew formation and temperature and their effects on suppression of weeds by plant pathogens. Potential pathogen must be selected as a BCA. Previous studies suggest that these pathogens must (1) produce abundant and durable inoculum in artifical culture, (2) be genetically stable and weed specific and (3) kill weeds in control. A granular preparation of mycoherbicide into sodium alginate is lighter than liquids and less bulky than organic matter. Gel forms have also been used.

• Korean Journal of Psychosomatic Medicine
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• v.23 no.2
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• pp.107-113
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• 2015

Objectives : The aim of this study was to investigate the factors including possibility of bipolar disorder that are related to intensity of suicidal idea. Methods : The study subjects consisted of 50 patients who did suicidal attempt and treated at the Inje University Haeundae Paik Hospital Emergency Room. All participants underwent psychiatric interview and underwent Columbia Suicide Severity Rating Scale(C-SSRS), Beck Depression Inventory(BDI), Korean Version of Mood Disorder Questionnaire(MDQ) and Bipolar Spectrum Diagnostic Scale(BSDS) to evaluate patient's suicide attempt, severity of depression and possibility of bipolar disorder. Results : Compared to non-high risk group, suicide high risk group showed significantly higher BDI(p<0.001) and intensity of ideation(IOI) in C-SSRS(p<0.001). Also intensity of ideation(IOI) was correlated with Mood Disorder Questionnaire(MDQ) bipolarity positive(p=0.033). Conclusions : The present study indicated that possibility of bipolar disorder plays a significant role in suicide attempters. Assessment of suicide ideation severity and possibility of bipolar disorder should be considered when suicide attempters come to emergency room.

• Korean journal of applied entomology
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• v.58 no.3
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• pp.251-258
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• 2019

A series of studies were conducted to monitor the seasonal occurrences of onion thrips (Thrips tabaci) and allium leafminers (Acrolepiopsis sapporensis) in northern-type garlic fields, and to evaluate their susceptibility to insecticides. The results showed that the T. tabaci population density increased from mid- March to mid-June, that of A. sapporensis began to increase in mid-March and peaked twice by early July. Also, using recommended concentrations, the insecticidal activities of nine insecticides against these two pests were evaluated. Under laboratory conditions, clothianidin SC, chlorfenapyr EC, dimethoate EC, imidacloprid WP, and cyantraniliprole + thiamethoxam WG insecticidal activities against T. tabaci were all 100%, as well as. those of cyantraniliprole EC, pyridalyl EW, spinetoram SG and abamectin + chlorantraniliprole SC against A. sapporensis. Insecticides, with high insecticidal activities, were evaluated on the two pests under laboratory conditions, and the results showed that all the insecticides exhibited strong insecticidal activities, and the mortality of two pests was >90%.

• Parasites, Hosts and Diseases
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• v.57 no.3
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• pp.265-271
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• 2019

The prevalence of human taeniasis has decreased in Korea. The stool egg positive proportion decreased from 1.9% in 1971 to 0% in 2004 in nationwide surveys. The neurocysticercosis (NCC) is also presumed to decrease. However, detailed information regarding the recent status of NCC in Korea is lacking. We retrospectively reviewed NCC cases from 1990 to 2016 at Asan Medical Center, a 2700-bed tertiary referral hospital in Korea. We identified patients based on clinical symptoms, brain imaging, pathology and serological assay. The cases were classified as parenchymal, extraparenchymal, and mixed NCC. Eighty-one patients were included in the analysis. The mean age was 54.5 years, and 79.0% were male. The number of NCC cases was highest from 1995 to 1999, and continuously decreased thereafter. Forty (49.4%) patients had parenchymal NCC, while 25 (30.9%) patients had extraparenchymal NCC, and 16 (19.8%) patients had mixed NCC. The seizure and headache were most common symptom of parenchymal NCC and extraparenchymal NCC respectively. Hydrocephalus was more common in extraparenchymal NCC, and patients with extraparenchymal NCC were more likely to require a ventriculoperitoneal shunt. Cases of NCC are decreasing accordingly with human taeniasis and lesion location was the most important determinant of clinical presentation and outcome of NCC in Korea.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.30 no.3
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• pp.181-189
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• 2019

In this study, a triple-band antenna that can be used in WLAN(Wireless Local Area Network) at 2.4 GHz, 5.8 GHz, and 5G at 3.5 GHz is fabricated. The proposed antenna uses a parasitic element to show the triple band, and the reflector is used at a distance of ${\lambda}/4$ from the antenna to reduce the Specific Absorption Rate(SAR). Its dimensions are $100{\times}75{\times}1.6mm^3$ and each parameter value is optimized for better performance and a lower SAR value. As a result, we obtained a bandwidth of 540 MHz(2.02~2.56 GHz), 390 MHz(3.39~3.78 GHz), and 1,210 MHz(5.56~6.77 GHz) based on the reflection loss factor of -10 dB. In addition, the SAR values of the antenna with reflector are observed to reduce below the SAR value of international standard.

• Journal of Breast Disease
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• v.6 no.2
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• pp.60-72
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• 2018

Purpose: According to American Society of Clinical Oncology/College of American Pathologists guidelines, breast cancer is human epidermal growth factor receptor 2 (HER2) positive if there is HER2 protein overexpression at a 3+ level on immunohistochemistry (IHC 3+) or gene amplification (more than six copies per nucleus) on fluorescence in situ hybridization (FISH+). However, there have been few reports on whether outcomes differ based on diagnosis by these two techniques. In this study, we compared outcomes based on the two methods in patients with HER2-positive breast cancer. Methods: This study was a retrospective analysis of HER2-positive breast cancer in 18,304 patients, including 14,652 IHC 3+ patients and 3,652 FISH+ patients from the Korean Breast Cancer Society Registry. We compared breast cancer-specific survival and overall survival based on IHC 3+ and FISH+ status with or without trastuzumab. Results: Breast cancer-specific survival was significantly different between the IHC 3+ and FISH+ groups, with 5-year cumulative survival rates of 95.0% for IHC 3+ and 98.5% for FISH+ patients who did not receive trastuzumab (p=0.001) in Kaplan-Meier methods. However, there were no significant differences in breast cancer-specific survival and overall survival between IHC 3+ and FISH+ groups regardless of trastuzumab treatment in Cox proportional hazards models. Conclusion: The survival outcomes were not affected by the different two diagnostic methods of HER2-positive breast cancer. Further research to evaluate differences in prognosis and other characteristics according to the diagnostic methods of HER2 positivity is needed in the future.