• Title/Summary/Keyword: Lee Mi-Ja

Search Result 1,011, Processing Time 0.034 seconds

Proteomic analysis of proteins Secreted by Human Bronchial Epithelial Cells in Response to Pathogenic Bacterial Infections

  • Oh, Mi-Jung;Park, Mi-Ja;Lee, Ji-Yeon;Park, Ji-Woo;Lee, Na-Gyong;Jung, Sung-Yun;Kim, Dae-Kyong
    • Proceedings of the PSK Conference
    • /
    • 2003.04a
    • /
    • pp.220-221
    • /
    • 2003

  • Bacterial infection is a very complex process in which both pathogens and host cells play crucial roles, and the host cells undergo drastic changes in their physiology, releasing various proteins in response to the pathogenic infection. Human airway epithelial surface serves as a first line of defense against microorganisms and the external environment. It is well known that bronchial epithelial cells secrete various chemokines and cytokines such as IL-6 and IL-8 to cope with various respiratory pathogens. (omitted)

  • PDF

A conditional lethal mutation of a nucleoporin gene, NUP49 in saccharomyces cerevisiae

  • Lee, Youn-Soo;Song, Young-Ja;Kyung, Hwang-Mi;Lee, Woo-Bok;Kim, Jin-Mi
    • Journal of Microbiology
    • /
    • v.35 no.3
    • /
    • pp.234-238
    • /
    • 1997

  • Conditional lethal mutation nup49-1 of a nuclear pore complex component gene was constructed in Saccharomyces cerevisiae. This mutation deleted one third of the essential NUP49 gene at the carboxy-terminal, but retained 13 repeats of the highly conserved GLFG domain. The nup49-1 mutant strain was viable with a slow-growth phenotype, indicating that the C-terminal is dispensable at normal growth temperature. This strain exhibited both temperature-sensitivity at 37.deg.C and cold-sensitivity at 16.deg.C. Temperature shift experiments revealed that the arrest phenotype at 37.deg.C was random in the cell division cycle. The nup49-1 mutation was tested to be recessive and is expected to be useful for the functional analysis of nuclear pore complex proteins as well as for studies of nuclear transport systems.

  • PDF

A Case with Emanuel Syndrome Resulting from a Maternal Balanced Translocation

  • Kim, Ja-Hye;Kim, Yoo-Mi;Lee, Beom-Hee;Kim, Ja-Hyung;Seo, Eul-Ju;Yoo, Han-Wook
    • Journal of Genetic Medicine
    • /
    • v.9 no.1
    • /
    • pp.35-37
    • /
    • 2012

  • Emanuel syndrome is a rare genomic syndrome which is characterized by multiple congenital anomalies and developmental disability. This syndrome is related to the presence of the supernumerary derivative chromosome originating from both chromosome 11 and 22. In most cases, one of the parents is a balanced carrier of a translocation. Our case results from 3:1 meiotic segregation of the maternal translocation carrier and is a rare case in Korea confirmed by genetic analysis.

  • https://doi.org/10.5734/JGM.2012.9.1.35 인용 PDF KSCI