• Journal of The Korean Society of Clinical Toxicology
• /
• v.4 no.1
• /
• pp.32-43
• /
• 2006

Purpose: Toxic Exposure Surveillance System (TESS) is widely used for poisoning data collection and making a counterplan. But, there were few reports about poisoning data collection using TESS in Korea. The aim was to collect poisoning data using TESS report form and investigate the recognition of emergency physician about the necessity of TESS as preliminary survey. Methods: Retrospectively, we gathered data from hospital records about the patient who admitted hospital emergency room due to poisoning. Date were gathered by paper and/or web client system report form in patients recruited by ICD-10 codes Results: From Jun 2004 to May 2005,3,203 patients were enrolled in 30 hospitals and their mean age was $44.9{\pm}20.3years$ old(male: female = 1,565: 1,638). The most frequent site of exposure was their own residence (73.2%, 2,345/3,203) and most of reported patients were older than 20 years(89.7%, 2,871/3,203). Frequent substances involved in poisoning were medication(41.9%) and pesticide(33.3%). Intentional poisoning was 60.7%(1,954). In fatality, overall frequency was 5.1%(162/3,203) and the most frequent route of exposure was ingestion(96.3%, 156/162) and the most frequent substance was pesticide(85.2%, 138/ 162). Antidotes were administered in 202 patients(2-PAM, atropine, antivenin, N-acetylcystein, vitamin K, flumazenil, ethanol, methylene blue, naloxone, calcium compound). 19 of 20 emergency physicians agreed with necessity of TESS. Conclusion: Data collection using TESS report form showed preliminary poisoning events in Korea. Frequent poisoning substance were medication and pesticide. The fatality was mainly related with pesticide ingestion. Many doctors in emergency room recognized the necessity of TESS.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.50 no.spc1
• /
• pp.56-61
• /
• 2005

This study was carried out to elucidate the proper nitrogen application level considering rice quality in Honam plain area from 2002 to 2004 at the paddy field of Honam Agricultural Research Institute. The rice cultivars tested were Samcheonbyeo (Early maturing one), Hwaseongbyeo (Medium maturing one) and Nampyeongbyeo (Mid-late maturing one). The results are summarized as follows: The higher amount of nitrogen application resulted in greater number of panicle and grain in per unit area, but the rate of ripening and the 1,000-grain weight of brown rice decreased. The protein contents showed a tendency of increase with higher nitrogen level. The head rice yield increased by the higher nitrogen application up to 7 kg/10a for Samcheonbyeo and Hwaseongbyeo, and 9 kg/10a for Nampyeongbyeo respectively. The appropriate nitrogen application amounts, with respect to the yield of head rice, the rate of ripening and the quality of rice were found to be in range of 7 to 9 kg/10a.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.50 no.spc1
• /
• pp.62-68
• /
• 2005

The characters associated with the rice quality and the factors as the proper harvesting time of rice were examined from 2002 to 2004 at Iksan in Honam plaine area. The rice cultivars tested were Samcheonbyeo (Early maturing one). Hwaseongbyeo(Medium maturing one) and Nampyeongbyeo(Mid-late maturing one). The ripened grain rates were high when the harvesting dates after heading were between 50 to 55 days,55 to 60 days, and 60 days for Samcheonbyeo, Hwaseongbyeo and Nampyeongbyeo, respectively. The yield of rice were higher when harvested 45 to 50 days, 50 to 55 days, and 55 to 60 days after heading for Samcheonbyeo, Hwaseongbyeo and Nampyeongbyeo. The highest yields of head rice were obtained when harvested 45 days after heading, 50 days and 55 to 60 days for Samcheonbyeo, Hwaseongbyeo and Nampyeongbyeo. In conclusion, in Honam plain, taking the head rice production, rice quality level, protein content and palatability of rice into account, the best harvest times were found to be 52 days(accumulated temp. : $1,213^{\circ}C$) after heading, 56 days$(1,221^{\circ}C)$, and 60 days $(1,207^{\circ}C)$, for Samcheonbyeo, Hwaseongbyeo and Nampyeongbyeo, respectively.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.96-96
• /
• 2017

Rice is a staple food for nearly half of the world's population, with more than 10,000 rice varieties providing almost one-quarter of the global per capita dietary energy supply. Grain size, panicle size and branch number, grain number in a panicle are directly associated with rice productivity. Recently several genes which increase grain yield were identified through map-based cloning. Gn1a, Cytokinin oxidase, is a major grain number QTL and regulates grain number per panicle. Dep1 increases panicle branching and reduced rachis length. SCM2 (APO1) was identified by a QTL for culm strength and increased spikelet number. OsSPL16 (GW8) controls grain size and shape and then increases 1000-weight of seed. In here, to identify genotype of genes related to yield in 400 of rice germplasms possessed in National Institute of Crop Science, we had first chosen 4 of well-known genes related to yield; Gn1a, Dep1, SCM2, and OsSPL16. Among these germplasms, 195, 382, 165, and 353 of germplasms harbored the dominant type of Gn1a, Dep1, SCM2, and OsSPL16, respectively. We grouped these germplasms into a total of 10 groups using genotypes of Gn1a, Dep1, SCM2 and OsSPL16. Most rice germplasms belong to group 1, harbored Gn1a, dep1, gw8 and APO1, and group 10, harbored gn1a, Dep1, GW8 and apo1. Hanareum2 is the highest productive cultivar in Korea but do not have dominant type OsSPL16, so belong to group 1. On the other hand, in the case of Unkwang, belongs to group 10, which has dominant type of OsSPL16 but do not have the remaining genes. We can grasp the differences in rice germplasms through the Profiling of genes related to these grain yield, which will be useful for cross-breeding to integrate grain yield genes. We are continuously observing the genotype and phenotype of rice that possesses grain yield genes.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.98-98
• /
• 2017

Leaf senescence is the process of aging in plants. Chlorophyll degradation during leaf senescence has the important role translocating nutrients from leaves to storage organs. The functional stay-green with slow leaf yellowing and photosynthesis activity maintenance has been considered one of strategy for increasing crop productivity. Here, we have identified two QTLs on chromosome 9 and 10 for leaf senescence with chlorophyll content of RIL population derived from a cross between Hanareum 2, early leaf senescence Indica-type variety, and Unkwang, delayed leaf senescence Japonica variety. Among these QTLs, we chose qPLS1 QTL on chromosome 9 for further study. qPLS1 was found to explain 14.4% of the total phenotypic variation with 11.2 of LOD score. Through fine-mapping approach, qPLS1 QTL locus was narrowed down to about 25kb in the marker interval between In/del-4-7-9 and In/del-5-9-4. There are 3 genes existed within 25kb of qPLS1 locus: LOC_Os09g36200, LOC_Os09g36210, and LOC_Os09g36220. Among these genes, transcript level of LOC_Os09g36200 was increased during the leaf senescence stage and the expression level of LOC_Os09g36200 in Indica was higher than in Japonica. Finally, we chose LOC_Os09g36200 as candidate gene and renamed it as OsPLS1-In and OsPLS1-Jp from Indica- and Japonica-type rice, respectively. OsPLS1-In and OsPLS1-Jp overexpressing transgenic plants showed both early leaf senescence phenotype. These results indicate that OsPLS1 functions in chlorophyll degradation and the difference of expression level of OsPLS1 cause the difference of leaf senescence between Indica and Japonica in rice.

• Journal of Dairy Science and Biotechnology
• /
• v.23 no.2
• /
• pp.93-98
• /
• 2005

Effects of heat and gamma irradiation on chemical, microbiological, and immunological changes of raw milk were compared. Free fatty acid content of milk showed increasing tendency according to the increase of heating temperature and irradiation dose, and showed similarity in UHT (ultra high temperature) and 5 kGy irradiation. Total bacterial counts and coliforms were not detected after treatment of LTLT (low temperature long time), HTST (high temperature short time), UHT, and irradiation from 1 to 10 kGy in the milk with initial microbial load at $10^3$ CFU/mL initially, but after 7 day storage, were not detected in UHT milk and that irradiated at 3 kGy or above. Heat treatment decreased (p<0.05) arginine, asparate, iso-leucine, lysine, and methionine content compared to raw milk while irradiation decreased (p<0.05) asparate, histidine, iso-luecine, leucine, and lysine content, which means irradiation could change primary structure of milk proteins. It was concluded that f kGy gamma irradiation treatment of raw milk could give a similar effect to UHT treatment in chemical and microbiological viewpoint, and may reduce allergenicity of raw milk.

• Korean Journal of Veterinary Service
• /
• v.42 no.4
• /
• pp.257-264
• /
• 2019

Mastoparan V1 was used as adjuvant of formalin-inactivated Salmonella Gallinarum whole cells vaccine against fowl typhoid in a chicken model. The 75 brown nick chickens were equally divided into 5 groups, and all chickens of each group were immunized at 6 weeks of age (0 WPPI; weeks prime post immunization), and at 9 weeks of age (3 WPPI) (except group B). Group A chickens were intramuscularly (IM) inoculated with 500 uL of sterile phosphate-buffered saline (PBS), and group B chickens were subcutaneously immunized with 0.2 ml containing 5×10⁷ viable vaccine strain/bird. The chickens in groups C~E were IM inoculated with approximately 3×10⁹ cells/0.5 mL of formalin-inactivated the S. Gallinarum whole cells, approximately 3×10⁹ cells/0.5 mL of formalin-inactivated the S. Gallinarum whole cells with mastoparan V1 as adjuvant, and 0.5 mL of PBS, respectively. S. Gallinarum outer membrane proteins-specific serum IgG titers were considerably higher in groups B~D than in groups A and E. However, the levels of IFN-γ in groups B and D only than in groups A and E were significantly higher. Following oral challenge with virulent wild-type S. Gallinarum, no chicken in groups A (no challenge group) and B was dead, and only 30% of chickens in group D was dead. However, 70% of chickens in group C and all chickens in group E were dead after oral challenge. The results of this study demonstrated that IM immunization with approximately 3×10⁹ of the formalin-inactivated S. Gallinarum whole cells containing mastoparan V1 induced robust antibody and cell-mediated immune responses in chickens. The whole cells also conferred protection against infection with wild-type S. Gallinarum.

• Journal of the Korean earth science society
• /
• v.26 no.3
• /
• pp.253-267
• /
• 2005

Seasonal and spatial variations of tidal flat sediments were studied in Yeoja Bay. Results of the yearly observation of tidal flat transect lines indicated that the monthly change of grain size composition was not distinct from each tidal flat transect line, but it was quite clear that clay covered $40\~70\%$ of the sediment composition. Clay composed most highest in the northern part of the bay, and lowest in the western. As clay content increased, water and organic matter showed a tendency of increase, while the mean grain size was fixed per clay amount. Shear strength came out as 0 kPa as a whole. Seasonal variations of clay contents in each tidal flat were higher in winter and spring, but lower in summer and autumn. Thefine sediments were likely to be accumulated in the winter and spring. The average accumulation rate of each tidal flat was $-14.62\~38.57mm{\cdot}yr^{-1}$. The numbers showed $32.13mm{\cdot}yr^{-1}$ in the northern, $-14.62mm{\cdot}yr^{-1}$in the western, and $6.46mm{\cdot}yr^{-1}$ in the eastern part. During the coarse of this study sediment accumulation rates indicated that the sediments deposited continuously in the northern part of tidal flat, whereas erosion occurred in the western part. However, there was no distinct change in the eastern part. It was due to the clockwise lateral circulation in Yeoja Bay. Seasonally, sedimentation happened during the dry season (winter and spring) and erosion during the wet season (summer and autumn).

• Journal of Gastric Cancer
• /
• v.16 no.4
• /
• pp.207-214
• /
• 2016

Purpose: The utility of N classification has been questioned after the 7th edition of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC) was published. We evaluated the correlation between ratio-based N (rN) classification with the overall survival of pathological T4 gastric cancer patients who underwent D2 lymphadenectomy. Materials and Methods: We reviewed 222 cases of advanced gastric cancer patients who underwent curative gastrectomy between January 2006 and December 2015. The T4 gastric cancer patents were classified into four groups according to the lymph node ratio (the number of metastatic lymph nodes divided by the retrieved lymph nodes): rN0, 0%; rN1, ${\leq}13.3%$; rN2, ${\leq}40.0%$; and rN3, >40.0%. Results: The rN stage showed a large down stage migration compared with pathological T4N3 (AJCC/UICC). There was a significant difference in overall survival between rN2 and rN3 groups in patients with pT4N3 (P=0.013). In contrast, the difference in metastatic lymph nodes was not significant in these patients (${\geq}16$ vs. <15; P=0.177). In addition, the rN staging system showed a more distinct difference in overall survival than the pN staging system for pathological T4 gastric cancer patients. Conclusions: Our results confirm that rN staging could be a good alternative for pathological T4 gastric cancer patients who undergo D2 lymphadenectomy. However, before applying this system to gastric cancer patients who undergo D2 lymphadenectomy, a larger sample size is required to further evaluate the usefulness of the rN staging system for all stages, including less advanced stages.

• Asian-Australasian Journal of Animal Sciences
• /
• v.29 no.4
• /
• pp.599-605
• /
• 2016

In this study, two experiments were conducted to investigate the physicochemical characteristics (Exp. I) of bedding materials such as rice hulls (RH), sawdust (SD), wood shavings (WS) and sawdust+wood shavings (S+W; 1:1 in volume), and utilization of these beddings except RH (Exp. II) for rearing beef cattle. In Exp. I, the distribution of particle size (%) with $250{\mu}m$ and below $250{\mu}m$ was greater (p<0.05) in SD (30.4) than RH (4.4), WS (18.8) and S+W (20.1). Bulk density ($kg/m^3$) of bedding materials was directly proportional to the percentage of $250{\mu}m$ and below $250{\mu}m$ particles, 178, 46, 112, and 88 for SD, WD, S+W and RH, respectively. Water absorption rate (%) after submersion in water for 24 h was higher (p<0.05) in WS (540.2) compared to SD (270.2), S+W (368.2). The S+W had an intermediate value of the absorption rate between SD and WS, but had an outstanding durability of water absorption capacity. Moisture evaporation rate (%) for 12 h was higher (p<0.05) in WS (75.4) than SD (70.5), S+W (72.2) and RH (57.8). Average ammonia emission ($mg/m^2/h$) for 36 h was higher (p<0.05) in RH (3.15) than SD (1.70), WS (1.63), and S+W (1.73). In Exp. II, thirty six Hanwoo cows were allocated in 9 pens with one side on feed bunk side (Side A) and another side equipped with water supply (Side B) for 3 weeks with duplicated periods. Average moisture concentrations (%) of beddings were higher (p<0.05) in WS (side A, 65.7; side B, 57.9) than SD (side A, 62.5; side B, 52.2) and S+W (side A, 61.6; side B, 50.7). Regardless of types of beddings, moisture concentrations (%) of beddings within a pen were lower (p<0.05) at side B than A, implying longer period of utilization. These results suggest that using S+W would be a better choice than SD or WS alone, considering physicochemical characteristics and economics, and RH is not a suitable material as a bedding for beef cattle.