• Title/Summary/Keyword: Lecithin

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Characteristics of Lecithin-adsorbed Magnetic Nanoparticle and Biocompatibility of Its Fluid (Lecithin이 흡착된 나노 자성입자의 특성과 그 자성유체의 생체 친화성)

  • Park, Sang-Im;Kim, Chong-Oh;Kim, Jong-Hee;Kim, Seong-Min;Kim, Keun-Ho
    • Journal of the Korean Magnetics Society
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    • v.16 no.6
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    • pp.293-299
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    • 2006
  • Magnetic nanoparticles were prepared by thermal decomposition and adsorbed with lecithin by applying ultrasonic. The size and saturation magnetization of magnetic nanoparticles were observed with different lecithin concentration, and the maximum tolerated dose (HTD) and toxicity of magnetic fluid was investigated through a biological test. The thickness of lecithin-adsorption layer increased non-linearly with increasing amounts of added lecithin, and the desirable adsorption amount was observed in the lecithin concentration of 20%(w/v). The dispersibility and magnetic properties of lecithin-adsorbed magnetic nanoparticles were most excellent when the ultrasonic exposure time was 1.5h. Also, the maximum tolerated concentration with best cell viability was $32{\mu}g/ml$ in vitro test, and lecithin-adsorbed magnetic fluids improved the biocompatibility by 1.2 times compared with bare magnetite fluids in vivo.

A Study on the Utilization of Soy-Lecithin in Broiler Ration (Broiler에 있어서 대두 Lecithin의 사료적 가치에 관한 연구)

  • 김대진;김영길
    • Korean Journal of Poultry Science
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    • v.7 no.1
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    • pp.23-29
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    • 1980
  • The research was conducted to study the feeding value of crude soylecithin produced as by-products of soybean oil manufacturing in broiler ration. The results obtained were as follows. 1. The chemical composition, mineral composition, Vitamine contents and gross energy values of crude soy-lecithin were determined 2. No significant difference was observed for the body weight gain of broiler between control and lecithin groups of 3%, 6%, 9o/e and 12% addition. 3. Significant difference (P<0.05) was observed for feed intake lecithin 12% composed with lecithin 6% and 9% group, However, no significant difference was found among control, lecithin 3%, 6%, and 9% groups. 4. No significant difference was found for feed conversion between treatments. However, the lowest figure 2.32 for lecithin 9% treatments, followed by 2.40 of lecithin 6% and 2.41 of lecithin 3% orderly. 5. The composition of moisture, crude protein and ether extract in broiler carcas ranged from 71.2 to 72.15%, from 15.93 to 16.45% and from 6.19 to 7.05% respectively. 6. The weight of abdominal fat and live fat in broiler caress ranged from 42.4 to 63.7 gm, and from 2.2 to 2.4gm respectively. difference between abdominal and live fat weight was showing in significant statistically. 7. The present data reveal that soy-lecithin as by-product of soybean oil manufacturing was valuable energy source.

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Hypocholesterolemic Effects of Soybean Lecithin in Cholesterol-Fed Rats

  • Moon Min-Sun;Kwun In-Sook;Kim Yangha
    • Nutritional Sciences
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    • v.8 no.4
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    • pp.237-241
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    • 2005
  • The present study was performed to elucidate the hypocholesterolemic action of lecithin on the diet-induced hypercholesterolemia in rats. Male Sprague-Dawley rats (n=24) were fed lecithin-free (control) diet or diets containing $2\%\;or\;5\%$ lecithin for 4 weeks. Hypercholesterolemia was induced by adding $1\%$ cholesterol and $0.5\%$ cholic acid to all diets. No difference was found in food intake and body weight gain among groups. The lecithin treated groups showed significant improvement in the plasma levels of total cholesterol and LDL-cholesterol (p<0.05) compared to the control group, while the plasma triacylglyceride was not significantly affected 1he atherogenic index and HDL-cholesterol level were decreased in the lecithin groups. The diets with $2\%\;or\;5\%$ lecithin significantly decreased the activity of cholestetyl ester transfer protein (CETP) by $14\%\;or\;17\%$, respectively. Also, lecithin diets increased the activity of lecithin: cholesterol acyltransferase (LCAT). These results suggest that lecithin accounts for the hypocholesterolemic effect due to the decreased CETP activity and increased LCAT activity.

Effect of Lecithin on Dermal Safety of Nanoemulsion Prepared from Hydrogenated Lecithin and Silicone Oil

  • Bae, Duck-Hwan;Shin, Jae-Sup;Shin, Gwi-Su;Jin, Fan-Long;Park, Soo-Jin
    • Bulletin of the Korean Chemical Society
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    • v.30 no.4
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    • pp.821-824
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    • 2009
  • In this study, a hydrogenated lecithin-containing nanoemulsion was prepared from hydrogenated lecithin and silicone oil. Tween-60 and liquid paraffin, widely known emulsifiers, were used as standard substances, and high shear was produced by utilizing a high shear homogenizer and microfluidizer. The properties of the nanoemulsion prepared with hydrogenated lecithin were evaluated by measuring interfacial tension, dynamic interfacial tension, droplet size, zeta-potential, friction force, skin surface hygrometery, and dermal safety. The interfacial tension of lecinol S10/silicone oil was lower than that of lecinol S10/liquid paraffin. The nanoemulsion prepared from hydrogenated lecithin shows lower zeta-potential, skin surface hygrometery, and friction force compared with a general emulsion. The silicone nanoemulsion prepared from hydrogenated lecithin showed a zero value in the patch test and thus exhibits high dermal safety.

Effects of Temperature on the Rheology of Lecithin/CaCl2 Organogels (Lecithin/CaCl2 유기젤의 온도 영향에 대한 유변학적 연구)

  • Jung, Yeon-Geon;Lee, Hee-Young
    • Applied Chemistry for Engineering
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    • v.29 no.2
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    • pp.244-247
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    • 2018
  • Lecithin, a zwitterionic phospholipid, forms spherical reverse micelles in organic solvents such as decane. The addition of multivalent ions like calcium chloride to lecithin organosols induces the transformation of organosols into organogels. A variety of applications of such organogels were found in gelation of fuels, food processing and drug delivery. Here, we investigated the effect of temperature on their rheological properties. In particular, the organogels showed a distinct melting temperature (${\sim}95^{\circ}C$) and their elastic properties decreased with increasing temperature. This is maybe due to the fact that the electrostatic interaction between lecithin and calcium chloride could be weaken with increasing temperature.

Studies on the Isolation, Refining and Utilization of Lecithin from Skipjack Viscera Oil 2. The Utilization of Lecithin (참치 내장유 중에서 레시틴의 분리, 정제 및 이용에 관한 연구 2. 레시틴의 이용)

  • KIM Kui-Shik
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.6
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    • pp.901-907
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    • 1998
  • The refined lecithin derived from skipjack viscera oil was added to fish sausage and then the quality stability of the fish sausage during storage was studied. The fish sausages with the lecithin (lecithin $0\%$, A; $2\%$, B: $4\%$, C; $6\%$, D) were shown low level for peroxide value, carbonyl value and acid value compared to that without the lecithin, when they were stored for 40 days at $5^{\circ}C$. The fish sausage with the lecithin was also almost unchanged in polyunsaturated fatty acid compositions such as 22:6 (n-3) and 20:5 (n-3) during storage. Before storage, both the sausages with and without the lecithin were almost unchanged in their sensory score, but the sensory scores were decreased with storage. As a result from sensory score, the sausage contained $2\%$ of lecithin (B) was similar to that of $0\%$ lecithin (A). However, all the samples were kept their oxidative stabilities for 40 days at $5^{\circ}C$.

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Effect of Lecithin Intake on Lipid Metabolism and Antioxidative Capacity in Rats Fed High Fat Diet (레시틴섭취가 고지방 식이를 섭취한 흰쥐의 지방대사와 항산화능에 미치는 영향)

  • Yang, Su-Young;Hong, So-Young;Sung, Mi-Kyung;Kang, Myung-Hee;Kim, Mi-Kyung
    • Journal of Nutrition and Health
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    • v.40 no.4
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    • pp.312-319
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    • 2007
  • This study was performed to investigate the effect of lecithin on lipid metabolism and antixidative capacity in 9-week-old rats. Forty-five male Sprague-Dawley rats weighing 249.8 g were blocked into three groups according to their body weight and raised for 8 weeks with experimental diets containing 1% (LM) or 5% lecithin (LH) and control (C) diet. Plasma and liver total lipids, triglyceride, total cholesterol and plasma HDL-cholesterol concenterations, and fecal total lipids, triglyceride, total cholesterol and bile acid excretions were measured. Malondialdehyde (MDA) levels in plasma, liver, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities in red blood cell and liver, xanthine oxidase (XO) activities in plasma and liver, and total antioxidant status (TAS) in plasma were also measured. Effect of lecithin intake on antioxidative capacity was not significantly different among all the groups. Plasma total lipids, triglyceride and total cholesterol levels were lower in lecithin groups compared to control group, and these three lipid levels of lecithin groups were lowered dose-dependently as dietary lecithin level increased. But liver total lipids, triglyceride and total cholesterol levels were not different among all the groups. Also fecal total lipids, triglyceride and total cholesterol excretions were highest in high lecithin groups compared to two other groups. Thus it is plausible that lecithin intake decreases plasma lipid levels through increasing fecal lipid excretions, and may be beneficial for treatment and prevention of hyperlipidemia, but has no effect on antioxidative capacity.

Properties of Oil-in-Water Nano-emulsions Prepared from Hydrogenated Lecithin with High Pressure Homogenizer

  • Cho, Wan-Goo;Bae, Duck-Whan
    • Journal of the Korean Applied Science and Technology
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    • v.28 no.1
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    • pp.1-5
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    • 2011
  • In this study, We investigated the properites of nano-emulsions containing hydrogenated lecithin prepared by high pressure homogenizer. The size of droplet of emulsions prepared by homogenizer at various rpm (rotation per minute) was not measured due to the unstability of emulsions, however, the size of droplet of nano-emulsions prepared by high pressure homogenizer was around 300 nm and the appearance of emulsions was bluish. The stability of emulsions with various lecithin concentration was tested against time. POV (Peroxide value) of emulsions were plotted against time. POVs of emulsions prepared with an egg lecithin and a soy lecithin were increased with time, however, POV of emulsion with Lecinol S-$10^{(R)}$ was kept constant within 60 hours and at $60^{\circ}C$. In consumer test, the nano-emulsion showed higher affinity regardless of skin type. Both of irritation scores of emulsions were similar.

Effect of Soybean Lecithin on the Thermal Oxidation of Tocopherol in Blended Oil (혼합유중(混合油中) Tocopherol의 열산화(熱酸化)에 미치는 대두(大豆) Lecithin의 효과(效果))

  • Chang, Hyun-Ki
    • Journal of the Korean Applied Science and Technology
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    • v.10 no.2
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    • pp.1-6
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    • 1993
  • The blended oil was prepared from cottonseed oil and palm olien. The oxidative stability of blended oil after the addition of natural tocopherol and soybean lecithin during heating was investigated and the effects of lecithin were evaluated. The result obtained were as follows: 1. When the concentration of palm olein in blended oil during heating was increased, the oxidative stability was improved. 2. By both addition of natural tocopherol and soybean lecithin during heating in blended oil, induction period was considerably increased and residual ratio of tocopherol was high. 3. The oxidative stability of potato chips prepared from blended oil was higher in the prsence of lecithin than in the absence of it.

Effects of Replacing Soy-oil with Soy-lecithin on Growth Performance, Nutrient Utilization and Serum Parameters of Broilers Fed Corn-based Diets

  • Huang, Jin;Yang, Dandan;Wang, Tian
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.12
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    • pp.1880-1886
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    • 2007
  • This study was conducted to examine the effects of different soy-oil and soy-lecithin levels on growth performance, nutrient utilization and serum parameters in broiler chickens. Two hundred and forty 1-day-old Arbor Acres chicks were randomly divided into 4 groups and treated as follows: basal diet with 2% soy-oil (SO); soy-oil and soy-lecithin mixture in proportion of 75/25 (SOL1), 50/50 (SOL2) and 2% lecithin (SL). At the end of the trial (42 d), birds in SOL1 group grew faster (p<0.05) and had better feed conversion efficiency (p<0.05) than other groups while SL group had the lowest performance (p<0.05). The utilization of ether extract was improved in SOL1 group (p<0.05) but apparent metabolizable energy (AME) and utilization of other nutrients decreased in SOL2 and SL group from 19 to 21 d. No significant effects were observed in apparent metabolizable energy, dry matter, crude protein and ether extract but the utilization of calcium and phosphorus was significantly improved in SL group (p<0.05) during 39 to 42 d. The birds fed with lecithin had lower serum total cholesterol and triglyceride than the control group (SO). Broilers fed with 2% lecithin (SL) had the highest insulin level (p<0.05). The results implied that soy-lecithin and soy-oil in a proportion of 25:75 had the highest growth performance and that soy-lecithin had cholesterol lowering capacity.