• Title/Summary/Keyword: Least Square Regression

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A New Hot-Plate Method using Threshold Temperature; its Application on the Study of the Interaction between Naloxone or Diazepam and Morphine (신열판실험방법(新熱板實驗方法)에 의(依)한 Naloxone과 Diazepam이 Morphine 진통효과(鎭痛效果)에 미치는 영향(影響)에 관(關)한 검색(檢索))

  • Moon, Young-Hwan;Chun, Boe-Gwun
    • The Korean Journal of Pharmacology
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    • v.18 no.2
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    • pp.45-50
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    • 1982
  • Yeum et al. formulated a new hot-plate method using the threshold temperature, and there are some controversies on the effects of naloxone and diazepam on the antinociceptive action. In this paper, the comparison of three methods registering analgesic activity and the application of the new hot-plate method formulated by Yeum et al. on the study of the influences of naloxone and diazepam on the analgesic effect of morphine were tried in male mice. The results obtained were summarized as follows; 1) The least-square regression lines of the morphine analgesia plotted against log-dose showed the correlation coefficient of above 0.90, but the competitive antagonism produced by naloxone (0.1 mg/kg) against the analgesia was more prominently demonstated by the new hot-plate method than the other methods: original hot-plate method and electrical stimulation method. 2) In the experiment using the new hot-plate method, the log dose-response curve of morphine (y=7.30 x+49.80, r=0.998) was shifted to the right by the pretreatment of naloxone (0.1 mg/kg), but was slightly shifted to the left by the pretreatment of diazepam (2.5 mg/kg). This study suggests that for the analgesia experiment, the new hot-plate method is superior to the original hot-plate method or the electrical stimulation method, and that the potentiative effect of diazepam on the morphine anagesia is not significant.

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Assessing Process and Method Improvement of Reliability Growth Test Data with Growth Rate Changing During Testing (신뢰성성장시험 중 발생한 신뢰성성장률 변화를 고려한 고장 평가과정 및 평가방법 개선에 대한 연구)

  • So, Young-Kug;Jeon, Young-Rok;Ryu, Byeong-Jin
    • Journal of Applied Reliability
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    • v.14 no.2
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    • pp.129-136
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    • 2014
  • Reliability test is focusing to detect the unexpected reliability failure and solve them for the high quality of products. The test data should be used to assess and project the current level of interesting product reliability and so it is very important to have the accurately assessing methodology with test data. There are two type of trend for test data as constant and changing one during testing and this paper shows the difference in the assessing results of these two cases. There is less information how to define the existence of reliability growth rate changing and calculate the parameters of the reliability growth models to make an accurate assessment with such condition, so i established the process and mathematical model to calculate the parameters at such condition to make reliability growth curve with high Goodness of Fit. I validated the new method with the data made from Monte Carlo Simulation and case from Demko (1993). Even the assessed result with the new methodology may be different with the case by case because of very diversity in test condition and testing product quality, but the process and method founded in this research can be applied to any case using Duane and AMSAA model for their test data assessment. I also present the evaluation method to see the effectiveness with new one which is a conventional knowledge and not popular to use, so it is possible to compare the results with the newly presented and conventional method for better business decision.

The Relationship between Hormone Replacement Therapy and Periodontal Disease in Postmenopausal Women

  • Ahn, Eunsuk;Lee, Yunhee
    • Journal of dental hygiene science
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    • v.18 no.1
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    • pp.9-17
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    • 2018
  • The purpose of this study was to investigate the relationship between hormone replacement therapy (HRT) and periodontal disease in postmenopausal women using data from the 4th and 5th Korea National Health and Nutrition Examination Survey. A total of 5,482 postmenopausal women aged 45~75 years were included as study subjects in the final analysis. The HRT group comprised 1,035 postmenopausal women who had received HRT for at least one month, and the non-HRT group comprised 4,447 postmenopausal women who did not receive HRT. The chi-square test was used to confirm the bivariate relationship between the variables. Multinomial logistic regression analysis was used to adjust for covariance (age, education, family income, body mass index, age of menopause, alcohol, smoking, dental visit <1 per year, use of oral care products, and frequency of tooth brushing per day). After adjusting for all covariates, HRT was found to be associated with periodontal disease. In particular, the relationship between HRT and periodontal disease was more evident in older women and women younger than 45 years of menopausal age. The relationship between HRT and periodontal disease was stronger in women who brushed their teeth less than 3 times per day, women without regular oral examination, and women who did not use oral hygiene products. The results of this study confirmed the importance of actively considering hormone therapy when determining policy recommendations for postmenopausal women. Especially, health programs such as HRT, regular dental examination, and oral care are needed for older women who have undergone premature menopause.

Sensory Characteristics and Consumer Acceptance of Frozen Cooked Rice by a Rapid Freezing Process Compared to Homemade and Aseptic Packaged Cooked Rice

  • Kwak, Han Sub;Kim, Hye-Gyeong;Kim, Hyun Suk;Ahn, Yong Sik;Jung, Kyunghee;Jeong, Hyo-Young;Kim, Tae Hyeong
    • Preventive Nutrition and Food Science
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    • v.18 no.1
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    • pp.67-75
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    • 2013
  • Descriptive analysis and consumer acceptance tests were conducted with frozen (FCR), homemade (HCR), and aseptic-packaged (ACR) cooked rice products from two cultivars-IM and SD. FCR was prepared using a rapid freezing process, which may provide consumers with a quality similar to that of HCR. The intensity of the flavors of roasted, glutinous rice, rice cake, and rice starch and the textures of glutinousness, moistness, chunkiness, adhesiveness, and squishiness were all greater in the FCR as compared to the HCR and ACR (p<0.05) in IM and SD cultivars. The differences in sensory characteristics between the FCR and ACR were larger than the equivalent differences between the FCR and HCR. Overall consumer acceptance ratings for FCR in overall aspect, appearance, aroma, and texture were not significantly different compared to those for HCR (p>0.05); however, in most cases these factors showed significant differences when compared with ACR (p<0.05). From partial least square regression analysis, cooked rice was positively related to sweet, transparency, glossiness, roasted, glutinousness, chunkiness, moistness, glutinous rice, adhesiveness, rice shape, rice starch, and squishiness attributes but negatively related to raw rice, old rice, old rice aroma, a particle feeling, off-aroma, white color, scatteredness, slickness, size of cooked rice, and firmness attributes.

A Study on the Geomorphologic Synthesis of Hydrologic Response (수문응답의 지형학적 합성방법에 관한 연구)

  • Cho, Hong Je;Lee, Sang Bae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.10 no.1
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    • pp.99-108
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    • 1990
  • A Synthetic Unit Hydrograph Method was investigated for representation of the effective rainfall-direct runoff hydrograph by using a Geomorphologic Instantaneous Unit Hydrograpb(GIUH) proposed by Gupta et al(1980). The response function of the basin was assumed to be the two-parameter gamma probability density function. The physical parameters of the response function(Nash Model) was determined by using the regression eqs. were parameterized in terms of Horton order ratios and the relations between the basin lag time and time-scale parameter. The capability of the Synthetic Unit Hydrograph to the real basin was tested for the Pyungchang river basin and Wi Stream basin, and its capability to reproduce the hydrologic response was investigate and compared with the Moment Method and the Least Square Method used incomplete gamma function. The representation of the peak flow, the time to peak and the hydrographs the derived Synthetic Unit Hydrograph were tested on some obseved flood data and showed promising, and it was approved to be used for prediction of the ungaged basins.

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Distribution and Determinants of Out-of-pocket Healthcare Expenditures in Bangladesh

  • Mahumud, Rashidul Alam;Sarker, Abdur Razzaque;Sultana, Marufa;Islam, Ziaul;Khan, Jahangir;Morton, Alec
    • Journal of Preventive Medicine and Public Health
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    • v.50 no.2
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    • pp.91-99
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    • 2017
  • Objectives: As in many low-income and middle-income countries, out-of-pocket (OOP) payments by patients or their families are a key healthcare financing mechanism in Bangladesh that leads to economic burdens for households. The objective of this study was to identify whether and to what extent socioeconomic, demographic, and behavioral factors of the population had an impact on OOP expenditures in Bangladesh. Methods: A total of 12 400 patients who had paid to receive any type of healthcare services within the previous 30 days were analyzed from the Bangladesh Household Income and Expenditure Survey data, 2010. We employed regression analysis for identify factors influencing OOP health expenditures using the ordinary least square method. Results: The mean total OOP healthcare expenditures was US dollar (USD) 27.66; while, the cost of medicines (USD 16.98) was the highest cost driver (61% of total OOP healthcare expenditure). In addition, this study identified age, sex, marital status, place of residence, and family wealth as significant factors associated with higher OOP healthcare expenditures. In contrary, unemployment and not receiving financial social benefits were inversely associated with OOP expenditures. Conclusions: The findings of this study can help decision-makers by clarifying the determinants of OOP, discussing the mechanisms driving these determinants, and there by underscoring the need to develop policy options for building stronger financial protection mechanisms. The government should consider devoting more resources to providing free or subsidized care. In parallel with government action, the development of other prudential and sustainable risk-pooling mechanisms may help attract enthusiastic subscribers to community-based health insurance schemes.

Effect of Meteorological Element on Growth and Yield of Sesame

  • Kwon, Byung-Sun;Shin, Jeong-Sik;Shin, Jong-Sup;Choi, Seong-Kyu;Seo, Young-Nam
    • Plant Resources
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    • v.5 no.3
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    • pp.196-201
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    • 2002
  • This study was conducted to investigate the relationships between yearly variations of climatic elements and yearly variations of productivity in sesame. In addition, correlation coefficients among yield and yield components were estimated. The data of yield and yield components were investigated for 10 years from 1992 to 2001. The meteorological data gathered at the Yeosu Weather Station for the same period were used to find out the relationships between climatic elements and productivity. Yearly variation of the amount of precipitation in July and September were large with coefficients of variation(c.v.) of 64.59, 92.47%, respectively, but the variation of the average temperature in June and August were relative small. Yield and plant height greatly with c. v. of 26.24, 23.41 %, respectively, 1, 000 grain weights show more or less c.v. of 3.83% and length capsule setting show still less variation. Correlation coefficients between maximun temperature in period of cultivation(from June to September) and yield are positively significant at the level of 5.1 %, respectively. Correlation coefficients amount the plant height, length capsule setting, number of capsules per plant, weight of 1, 000 grains and seed yield were positively significant at the level of 1 %, respectively. Simple linear regression equations by the least square method are estimated for number of capsules per plant(Y$_1$) and the maximun temperature in August(X) as $Y_1$=10.1255+0.1725X, and for yield(Y$_2$) and the maximun temperature in August(X) as $Y_2$=21.6151 + 1.3724X.

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Estimation of Total Displacements by RMR Grades using 3-Dimensional Numerical Analysis (3D 수치해석을 이용한 퇴적암 터널의 암반 등급별 전변위 산정)

  • Yim, Sung-Bin;Yun, Hyun-Seok;Seo, Yong-Seok;Park, Si-Hyun
    • The Journal of Engineering Geology
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    • v.17 no.2 s.52
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    • pp.217-224
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    • 2007
  • Tunnel displacement happens during the process of stress redistribution by tunnelling. Tunnel displacement can be divided into 3 types such as displacements occurring before excavation, non-measured displacements after excavation and measured displacements after excavation. Because measurements of displacements occurring before excavation and non-measured displacement after excavation are difficult and time-consuming in the field, many researchers have studied on total displacement and its characteristics with excavation using numerical analysis. In this study, we used a 3-D back analysis to estimate total displacement by rock mass grades in tunnel constructed in sedimentary rock. We reduced error between measured displacements and calculated displacements from a 3-D numerical analysis, and then estimated suitable rock mass properties by RMR classes. Ultimately, Logistic nonlinear regressions of total displacement with tunnelling were estimated by least square estimation.

Comparative Study on Fall Related Characteristics between Single and Recurrent Falls in Community-Dwelling Older Women (재가 여성노인에서 1회 낙상군과 반복낙상군의 낙상관련 특성 비교연구)

  • Park, Hyoung-Sook;Chang, Rang;Park, Kyung-Yeon
    • Korean Journal of Adult Nursing
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    • v.20 no.6
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    • pp.905-916
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    • 2008
  • Purpose: The purpose of this study was to identify the influencing factors on the single and recurrent falls in community-dwelling older women. Methods: Seventy eight volunteers aged over 65 were included in the study. The participants experienced at least one fall within the past one year. Data were measured on each participant from May 2007 to September 2007, collected using structured researcher-administered sheets and measuring their physical strengths and analyzed by descriptive statistics, t-test, chi-square test, Mann-Whitney U test and logistic regression analysis. Results: The prevalence of recurrent falls were 53.8%. The level of education(Z = -2.455, p = .014) and the presence of spouse($x^2$ = 4.843, p = .044) showed significant differences between the single-fall group and the recurrent-fall group in the study. Significantly predicting factor on the recurrent falls was the level of education and the variable explained 20.1% of variants in the occurrence of recurrent falls. Conclusion: Although a variety of factors affected the single fall in the elderly women, the level of education and the presence of spouse proved to be the significant factors in their recurrent falls. These factors proven to be significant as the result of this should be reflected in the development of effective programs for preventing the elderly from recurrent falls.

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Measurement of Bow in Silicon Solar Cell Using 3D Image Scanner (3D 스캔을 이용한 실리콘 태양전지의 휨 현상 측정 연구)

  • Yoon, Phil Young;Baek, Tae Hyeon;Song, Hee Eun;Chung, Haseung;Shin, Seungwon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.9
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    • pp.823-828
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    • 2013
  • To reduce the cost per watt of photovoltaic power, it is important to reduce the cell thickness of crystalline silicon solar cells. As the thickness of the silicon layer is reduced, two distinctive thermal expansion rates between the silicon and the aluminum layer induce bowing in a solar cell. With a thinner silicon layer, the bowing distance grows exponentially. Excessive bowing could damage the silicon wafer. In this study, we tried to measure an irregularly curved silicon solar cell more accurately using a 3D image scanner. For the detailed analysis of the three-dimensional bowing shape, a least square fit was applied to the point data from the scanned image. It has been found that the bowing distance and shape distortion increase with a decrease in the thickness of the silicon layer. An Ag strip on top of the silicon layer can reduce the bowing distance.