• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2014년도 제49차 동계학술대회논문집 22권1호
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• pp.189-191
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• 2014

This paper provides an overview of the E-learning service education on the last decade, In the early 2000's the emphasis of educational technology was on interactive multimedia- stand alone packages on computer hard disks or portable memory, which integrated a range of media forms in the lately. Customers handle finding the best sources of content.The system then uses social signals such as those coming from Facebook, Twitter, LinkedIn, delicious as well as clicks and views. The SNS and network infrastructure is sufficiently mature that the focus should shift to how to use the technology most appropriately to facilitate learning. As we study environmental conditions of the traditional internet and the mobile internet users in some ways. In this paper, analyze the nature of learning, role of educational and suggest alternative policy, innovation of e-learning service and effective e-learning environment in developing technology.

• 대한약학회:학술대회논문집
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• 대한약학회 2005년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.235-235
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• 2005

• 대한한의학방제학회지
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• 제25권1호
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• pp.69-87
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• 2017

Objectives : Cheongnoemyeongsin-hwan (CNMSH) is a herb medicine to treat cognitive impairment. This study was investigated the effects of CNMSH on learning and memory impairment induced by cerebral hypoperfusion. Cerebral hypoperfusion was produced chronically by permanent bilateral common carotid artery occlusion (BCCAO) in rats. Methods : CNMSH was administered orally once a day (250 mg/kg) for 28 days starting at 4th week after the BCCAO. The acquisition of learning and the retention of memory were tested on 9th week after the BCCAO using the Morris water maze. In addition, effect of CNMSH on neuronal apoptosis and ${\beta}-amyloid$ accumulation in the hippocmapus was evaluated with immunohistochemistry and Western blotting. Results : 1. CNMSH and ChAL significantly shortened the escape latencies on the 2nd day of acquisition training trials. 2. ChAL significantly prolonged the swimming time spent in the target and peri-target zones and CNMSH also significantly prolonged the swimming time spent in the peri-target zone. 3. CNMSH and ChAL significantly increased the number of target heading in the retention test. 4. ChAL significantly shortened the time of the 1st target heading in the retention test, but CNMSH insignificantly shortened the time of that. 5. CNMSH and ChAL significantly increased the memory score in the retention test. 6. CNMSH and ChAL significantly attenuated the reduction of CA1 neurons, but insignificantly attenuated the reduction of CA1 thickness. 7. CNMSH and ChAL significantly attenuated the up-regulation of Bax expression in the CA1 of hippocampus. 8. CNMSH and ChAL significantly attenuated the up-regulation of cascapse-3 expression in the CA1 of hippocampus. 9. CNMSH and ChAL significantly attenuated the ${\beta}-amyloid$ accumulation in the CA1 of hippocampus. 10. CNMSH and ChAL significantly attenuated the up-regulation of APP expression in the CA1 of hippocampus. 11. CNMSH and ChAL significantly attenuated the up-regulation of BACE-1 expression in the CA1 of hippocampus. Conclusions : The results show that CNMSH attenuates neuronal apoptosis and ${\beta}-amyloid$ accumulation in the hippocampus and alleviates the impairment of learning and memory produced by chronic cerebral hypoperfusion. These results suggest that CNMSH may be a beneficial medicinal herb to treat cognitive impairment associated with neurodegenerative diseases.

• 한국식품영양과학회지
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• 제39권3호
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• pp.376-382
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• 2010

본 연구는 BF-7이 어린이의 장기 및 단기 기억을 현저하게 촉진시킴을 보여주었다. 기존 임상 시험 결과를 통해 입증된 바와 같이 천연 소재인 BF-7의 안전성을 고려할 때, BF-7은 어린이 장기 및 단기 기억력, 기억유지도 및 기억의 효과적 활용 등 전반적인 기억 수행 능력 향상에 도움을 주는 매우 안전하면서 효과가 탁월한 천연소재임을 확인하였다.

• 부동산연구
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• 제27권3호
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• pp.71-86
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• 2017

본 연구의 목적은 딥 러닝 방법을 부동산가격지수 예측에 적용해보고, 기존의 시계열분석 방법과의 비교를 통해 부동산 시장 예측의 새로운 방법으로서 활용가능성을 확인하는 것이다. 딥 러닝(deep learning)방법인 DNN(Deep Neural Networks)모형 및 LSTM(Long Shot Term Memory networks)모형과 시계열분석 방법인 ARIMA(autoregressive integrated moving average)모형을 이용하여 여러 가지 부동산가격지수에 대한 예측을 시도하였다. 연구결과 첫째, 딥 러닝 방법의 예측력이 시계열분석 방법보다 우수한 것으로 나타났다. 둘째, 딥 러닝 방법 중에서는 DNN모형의 예측력이 LSTM모형의 예측력보다 우수하나 그 정도는 미미한 수준인 것으로 나타났다. 셋째, 딥 러닝 방법과 ARIMA모형은 부동산 가격지수(real estate price index) 중 아파트 실거래가격지수(housing sales price index)에 대한 예측력이 가장 부족한 것으로 나타났다. 향후 딥 러닝 방법을 활용함으로써 부동산 시장에 대한 예측의 정확성을 제고할 수 있을 것으로 기대된다.

• Transactions on Control, Automation and Systems Engineering
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• 제3권3호
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• pp.170-175
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• 2001

Q-learning is a kind of reinforcement learning where the agent solves the given task based on rewards received from the environment. Most research done in the field of Q-learning has focused on discrete domains, although the environment with which the agent must interact is generally continuous. Thus we need to devise some methods that enable Q-learning to be applicable to the continuous problem domain. In this paper, an extended fuzzy rule is proposed so that it can incorporate Q-learning. The interpolation technique, which is widely used in memory-based learning, is adopted to represent the appropriate Q value for current state and action pair in each extended fuzzy rule. The resulting structure based on the fuzzy inference system has the capability of solving the continuous state about the environment. The effectiveness of the proposed structure is shown through simulation on the cart-pole system.

• 농업과학연구
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• 제47권3호
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• pp.471-483
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• 2020

Flood prediction is an important issue to prevent damages by flood inundation caused by increasing high-intensity rainfall with climate change. In recent years, machine learning algorithms have been receiving attention in many scientific fields including hydrology, water resources, natural hazards, etc. The performance of a machine learning algorithm was investigated to predict the water elevation of a river in this study. The aim of this study was to develop a new method for securing a large enough lead time for flood defenses by predicting river water elevation using the a long- short-term memory (LSTM) technique. The water elevation data at the Oisong gauging station were selected to evaluate its applicability. The test data were the water elevation data measured by K-water from 15 February 2013 to 26 August 2018, approximately 5 years 6 months, at 1 hour intervals. To investigate the predictability of the data in terms of the data characteristics and the lead time of the prediction data, the data were divided into the same interval data (group-A) and time average data (group-B) set. Next, the predictability was evaluated by constructing a total of 36 cases. Based on the results, group-A had a more stable water elevation prediction skill compared to group-B with a lead time from 1 to 6 h. Thus, the LSTM technique using only measured water elevation data can be used for securing the appropriate lead time for flood defense in a river.

• 동의생리병리학회지
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• 제22권6호
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• pp.1487-1494
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• 2008

This study was conducted to determine the effect of Gagamjeongji-hwan (JJH)(Jiajiandingzhi-wan) and Evoidae Fructus (EF) on learning and memory disturbance and neuronal damage induced by focal ischemia in the rat. Rats were used for testing in the following three. Morris Water Maze, Cholineacetyltransferase (ChAT) immunohistochemistry, acetylcholine esterase (AchE) histochemistry. JJH+ISCH group (ischemia-induced rats pretreated with JJH) and EF+ISCH group (ischemia-induced rats pretreated with EF) significantly reduced the latency of swimming time, compared with those of ISCH group (ischemia-induced rats) in morris water maze acquisition test. JJH+ISCH group attenuated ischemia.induced learning and memory damage in morris water maze retention test. The density of ChAT neurons of the JJH+ISCH and EF+ISCH group in the hippocampal CA1 area was increased, compared to that of SAL+ISCH group (ischemia-induced rats pretreated with SAL). The density of AchE neurons of the JJH+ISCH and EF+ISCH group in the hippocampal CA1 and CA3 area was increased, compared to that of SAL+ISCH group. These results suggest that Gagamjeongji-hwan (JJH) and Evodiae Fructus (EF) may have significant protective effects on ischemia-induced brain damage and memory impairments.

• The Korean Journal of Physiology and Pharmacology
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• 제8권4호
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• pp.173-179
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• 2004

Amyloid ${\beta}-peptide\;(A{\beta})$ contributes to the pathogenesis of Alzheimer's disease (AD), causing neuronal death through apoptosis. In this study, the neuroprotective role of BF-7, extracted form sericultural product, was examined against $A{\beta}-induced$ toxicity in cultured human neuronal cell SKN-SH. In order to know if the BF-7 has positive role on the cognition and memory in human, the mixture of BF-7, DHA and EPA (BDE) was examined using Rey Kim and K-WAIS test with 50 healthy high school student. We report here that BDE significantly attenuated $A{\beta}-induced$ apoptosis through the reduction of ROS accumulation, and diminished caspase-like protease activity. Moreover, the memory index and memory preservation, and attentative concentration of BDE treated group for 1 month were significantly improved, in contrast to the case of placebo control treated with DHA and EPA. This result represent that the BF-7 play significant positive role on learning memory. Taken together, our result suggested the natural product BF-7 is a good substance for the brain functionally and physiologically.

• 생물정신의학
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• 제12권2호
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• pp.207-215
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• 2005

Objectives:This study was to compare verbal memory ability among patients with schizophrenia, bipolar manic patients and unipolar depressive patients, and to understand their charicteristics of memory process. Methods:All subjects were hospitalized patients and had been interviewed by using the Structured Clinical Interview for DSM-IV(SCID). Schizophrenic patients(N=40), bipolar manic patients(N=17), and unipolar depressive patients(N=20) were assessed with K-AVLT for verbal memory and with K-WAIS for verbal IQ. Three groups were compared regarding total immediate recall, delayed recall, delayed recognition, learning curve, memory retention, and retrieval efficiency under controlled verbal IQ. Multiple regression analysis was performed to find which clinical factors have an influence on verbal memory ability. Results:In MANCOVA, differences of verbal memory test scores among the groups were statistically significant(F=1.800, p<.05). In post hoc analysis, Patients with schizophrenia and bipolar mania showed poorer performance in immediate recall, delayed recall, delayed recognition, retrieval efficiency than unipolar depres- sive patients. And schizophrenics performed poorly in delayed recall, delayed recognition, retrieval efficiency than nonpsychotic affective disorder group, but no difference in total immediate recall, delayed recall, delayed recognition, retrieval efficiency between the schizophrenic group and the psychotic affective group. Conclusions:These results partially confirm previous reports of verbal memory ability among major psychiatric disorders. Our results showed that psychotic symptoms were related with verbal memory, and longer duration of illness was related with poorer performance in schizophrenia and unipolar depression.