• 제목/요약/키워드: Leading variety

검색결과 359건 처리시간 0.027초

ETHENO-DNA ADDUCTS AS OXIDATIVE STRESS-MARKERS IN CANCER ETIOLOGY AND CHEMOPREVENTION STUDIES

  • Bartsch, H.;Nair, J.;Owen, R.
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.24-25
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    • 2001
  • Persistent cellular oxidative stress and enhanced lipid peroxidation (LPO) of PUFAs, leading to macromolecular damage and disruption of signaling pathways, are implicated in the development of human malignancies and other chronic degenerative diseases. LPO generates by oxidation of linoleic acid (LA) or arachidonic acid ($\omega$ -6 PUPAs) reactive aldehydes, such as trans-4-hydroxy-2-nonenal, which form etheno $\varepsilon$ -DNA adducts in a variety of human tissues and thus can contribute to diet-related cancers.(omitted)

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Recent Advances in Filter Topologies and Realizations for Satellite Communications

  • Fahmi, Mohamed M.;Ruiz-Cruz, Jorge A.;Mansour, Rafaat R.;Zaki, Kawthar A.
    • Journal of Communications and Networks
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    • 제13권6호
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    • pp.625-632
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    • 2011
  • This paper presents an overview of recent advances in radio frequency and microwave filter topologies for satellite communication systems. Many types of filters have been developed during the last years in order to satisfy the demands of modern applications in both terrestrial systems and onboard spacecrafts, leading to a great variety of aspects such as transfer functions, resonator implementations or coupling structures. This paper revisits some of the last advances in this area, including the modeling and full-wave simulation. Some recent designs using dual-mode cavities along with other novel implementations in ridge waveguide will be shown.

Cardiomyopathies in small animals

  • Fujii, Yoko
    • 한국임상수의학회:학술대회논문집
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    • 한국임상수의학회 2009년도 춘계학술대회
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    • pp.127-133
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    • 2009
  • Cardiomyopathies were previously defined as "an idiopathic myocardial disease that is not secondary to any other type of congenital/acquired heart disease or systemic diseases." With increasing understanding of etiology and pathogenesis in human medicine, the difference between cardiomyopathy and specific heart muscle disease has become indistinct. Cardiomyopathies are now classified by the dominant pathophysiology or, if possible, by etiological/pathogenetic factors. The American Heart Association recently advocated the following new definition of cardiomyopathy: Cardiomyopathies are a heterogeneous group of diseases of the myocardium associated with mechanical and/or electrical dysfunction that usually (but not invariably) exhibit inappropriate ventricular hypertrophy or dilatation and are due to a variety of causes that frequently are genetic. Cardiomyopathies either are confined to the heart or are part of generalized systemic disorders, often leading to cardiovascular death or progressive heart failure-related disability. Because the understanding of etiology or pathogenesis of cardiomyopathy has been limited in veterinary medicine, the previous classification is generally used. It is considered a dilated, hypertrophic and restrictive group on the basis of the predominant morphological and functional abnormalities. In addition, arrhythmogenic right ventricular cardiomyopathy and unclassified cardiomyopathy were also recognized in dogs and/or cats.

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Bioactive secondary metabolites produced by fungi

  • Shim, Sang Hee
    • 한국균학회소식:학술대회논문집
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    • 한국균학회 2018년도 춘계학술대회 및 임시총회
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    • pp.49-49
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    • 2018
  • A variety of bioactive secondary metabolites have been reported from plant-associated microorganisms. Halophytes, plants that can only grow in hypersaline area, were reported to host beneficial microorganisms such as plant growth-promoting endophytes. The microorganisms have been reported to show notable mutualistic symbiosis with halophytes to help them survive in high saline condition. Finding out bioactive secondary metabolites as well as elucidation of relationship(s) between microbes and the host halophyte has been paid attention, because of their functional diversity. Novel microbes often have associated with novel natural products. In an effort to investigate natural compounds with interesting structures from fungi, we selected plants from a distinct environmental setting which could be a promising source. Several fungi were isolated from halophyte or medicinal plants. Some strains of the fungi were cultivated on a large scale and extracted with ethyl acetate, which were subjected to a series of chromatographic methods, leading to the isolation of tens of compounds. The isolated compounds were identified by analysis of spectroscopic methods such as 1D-, 2D-NMR, and MS. Details of isolation, structure determination, and biological activities will be discussed.

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Fluid mapper에 의한 철극형 전기기기의 자극 주변에서의 자속분포의 결정 (Determination of Magnetic Flux Distribution around the Salent Pole by means of the Fluid Mapper)

  • 우형주;고명삼
    • 전기의세계
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    • 제14권1호
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    • pp.35-39
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    • 1965
  • Field problems are solved by a variety of methods. In the relatively small number of cases that are simiple enough, the mathematical attack may be the method of choice. But many field problems with irregular boundary condition must be handled by the use of the electrolitic tank analog, conducting paper or the fluid mapper analog for the purpose of effectiveness and convenience. The method of choice depends on the actual of the problems. There is no one best way to solve all problems. The following points have been described in this apepr, 1. Theoretical studies are made of the vector which is produced by leading the fluid flow vector by a right angle. 2. Curvilinear square method is described., 3. Determination on magnetic flux distribution and variation according to the magnitude of exciting currents.

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초고속통신망 광케이블의 유지보수 및 시스템 발전방향 (Optical Super-highway Network Maintenance and System Trends)

  • 최신호;이병욱;박갑석;장은상;김성일
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1998년도 하계학술대회 논문집 G
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    • pp.2495-2497
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    • 1998
  • Fiber optic facilities are increasingly being deployed in loop applications for both busines and residential areas. These facilities support a variety of communications services that include high speed data and video using leading technologies such as Synchronous Optical Network (SONET), Wavelength Division Multiplexing(WDM). This proliferation of fiber optic facilities combined with the increasing pressure on network operators to reduce costs are fostering increased automation to reduce labor costs associated with providing and maintaining communications services. Effective fiber management and accurate records can improve the reliability and integrity of the future telecommunications networks and the quality of customer services. This paper describes the trend forward and the need for the deployment of Fiber Administration System (FAS) into the operations enviroment of a typical network provider.

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복합재료를 적용한 한국형 고속틸팅열차(TTX)의 차체 구조해석 연구 (A study on Structural Analysis of Korean Tilting Train eXpress(TTX) made of Composite Carbody Structures)

  • 신광복;구동회;박기진
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2003년도 추계학술대회 논문집(III)
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    • pp.98-102
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    • 2003
  • The use of composite materials for the carbody structures of tilting train has many advantages because of manufacturing variety, specific high-strength & stiffness characteristics, and long-life durability, but the strongest advantage is the possibility of lightweight product. In the leading countries, the composite materials are used for the material for drivers' cabs, interior/exterior equipments for railway train, and it is now developing the composite materials applied for the train carbody structure. In this paper, we conducted the evaluation of structural stability for the all aluminum carbody, all composite carbody and hybrid carbody structures of the Korean Tilting Train eXpress(TTX) with the service speed of 180km/h.

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금은화 플라보노이드성분의 항염증작용 (Anti-inflammatory Activity of the Flavonoid Components of Lonicera japonica)

  • 문태철;박정옥;정광원;손건호;김현표;강삼식;장현욱;정규찬
    • 약학회지
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    • 제43권1호
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    • pp.117-123
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    • 1999
  • Because of the potent effects of lipid mediators such as prostaglandins (PGs), leukotriens (LTs) and platelet activating factor (PAF) on a variety of cells and tissues, they are considered as major contributors to the process leading to inflammation and allergy. To pursue the mechanism of anti-inflammatory activity of Lonicera japonica, we tested inhibitory effects of 7 flavonoids from Lonicera japonica on arachidonic acid cascade related enzymes, such as inflammatory phospholipase $A_2$, cyclooxygenase-1 and 2, 5-lipoxygenase, in bone marrow derived mast cell (BMMC), and lyso PAF-acetyltransferase in rat spleen microsomes. Anti-inflammatory activities of lonicera japonica are thought to be attributed at least in part to the inhibition of arachidonic acid cascade releated enzymes by flavonoids such as apigenin, luteolin quercetin.

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소프트웨어 시험평가 모델 설계에 관한 연구(공공분야 CALS/EC 중심으로)

  • 임만택;이상호;김성용;변재정
    • 한국전자거래학회:학술대회논문집
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    • 한국전자거래학회 1999년도 학술대회지 vol.1
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    • pp.193-205
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    • 1999
  • Nowadays, public domain software CALS/EC projects give their attention to the importance of test and evaluation (T&E). This article proposed a survey on T&E procedures of the international standards ISO 9000-3, ISO/IEC 9126 and ISO 14598, and of the U.S. Army pamphlet as well as that of MIL-STD-498. And features of testing tools such as their characteristics were reviewed for a reference in selecting appropriate one. Large-scale software projects often encounter with problems during T&E, when they become close to the end of development cycle. The problems generally act as a bottleneck of a project, leading to slippage of the entire schedule. This article tried a close look at the problems and solution alternatives of the T&E policy, management, and technical issues, and proposed a T&E model to support a variety of software development environment.

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탄산칼륨 존재하에서 사염화규소를 이용한 알코올의 염소화반응 (Chlorination of Alcohols Using Potassium Carbonate and Silicon Tetrachloride)

  • 하동수;김형애
    • 대한화학회지
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    • 제41권10호
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    • pp.535-540
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    • 1997
  • 탄산칼륨 존재하에서 사염화규소는 1차, 2차, 3차 및 벤질알코올 유도체 뿐 만 아니라 시클로헥산올과 같은 고리형 알코올, 알릴 알코올등의 염소화반응에 효과적임을 알 수 있었다. 탄산칼륨이 사염화규소의 반응성이 큰 규소-염소 결합과 반응하여 생성될 수 있는 불안정한 중간체인 Trichlorosilyloxy carbonylchloride 혹은 최종적으로 평형농도 만큼 소량씩 생성되리라 예상되는 Phosgene은 모두 반응메카니즘적으로 알코올의 염소화반응에 관여할 수 있음을 알았다.

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