• Wind and Structures
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• v.22 no.6
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• pp.663-684
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• 2016

Conical vortices generated at the corner regions of large-span flat roofs have been investigated by using the Particle Image Velocimetry (PIV) technique. Mean and instantaneous vector fields for velocity, vorticity, and streamlines were measured at three visual planes and for two different flow angles of $15^{\circ}$. The results indicated that conical vortices occur when the wind is not perpendicular to the front edge. The location of the leading edge corresponding to the negative peak vorticity and maximum turbulent kinetic energy was found at the center of the conical vortex. The wind pressure reaches the maximum near the leading edge roof corner, and a triangle of severe suctions zone appears downstream. The mean pressure in uniform flow is greater than that under turbulent flow condition, while a significant increase in the fluctuating wind pressure occurs in turbulent streams. From its emergence to stability, the shape of the vortex cross-section is nearly elliptical, with increasing area. The angle that forms between the vortex axis and the leading edge is much smaller in turbulent streams. The detailed flow structures and characteristics obtained through FLUENT simulation are in agreement with the experimental results. The three dimensional (3-D) structure of the conical vortices is clearly observed from the comprehensive arrangement of several visual planes, and the inner link was established between the vortex evolution process, vortex core position and pressure distribution.

• Nuclear Engineering and Technology
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• v.48 no.1
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• pp.114-128
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• 2016

The development of operational performance indicators is of utmost importance for nuclear power plants, since they measure, track, and trend plant operation. Leading indicators are ideal for reducing the likelihood of consequential events. This paper describes the operational data analysis of the information contained in the Corrective Action Program. The methodology considers human error and organizational factors because of their large contribution to consequential events. The results include a tool developed from the data to be used for the identification, prediction, and reduction of the likelihood of significant consequential events. This tool is based on the resilience curve that was built from the plant's operational data. The stress is described by the number of unresolved condition reports. The strain is represented by the number of preventive maintenance tasks and other periodic work activities (i.e., baseline activities), as well as, closing open corrective actions assigned to different departments to resolve the condition reports (i.e., corrective action workload). Beyond the identified resilience threshold, the stress exceeds the station's ability to operate successfully and there is an increased likelihood that a consequential event will occur. A performance indicator is proposed to reduce the likelihood of consequential events at nuclear power plants.

• Korean Chemical Engineering Research
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• v.56 no.2
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• pp.212-221
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• 2018

Process safety incidents and loss events can be prevented if we identify and adequately take measures on process safety incident precursors in a timely manner. If we look into and take action against the process safety hazard factors causing the incident in the refinery and petrochemical plant, major process safety incidents can be prevented through eliminating or decreasing hazardous factors. We conducted a survey for the major process safety incident precursor to look specifically into the potential process safety hazardous factors of refineries and petrochemical plants in the Yeosu chemical complex. A self-assessment checklist, which was published by Center for Chemical Process Safety "Recognizing catastrophic incident warning signs in the process industry" on major incidents warning sign, was used for the survey. Through this survey, the major process safety incident leading indicators in the process industry were found by process safety management elements, and each site and/or facility can use these leading indicators for activities for process safety incident prevention. In addition, we proposed action items required to eliminate the root cause of those process safety incident leading indicators.

• Preventive Nutrition and Food Science
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• v.19 no.1
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• pp.1-4
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• 2014

Excessive ethanol intake is known to induce a number of physiological symptoms, including headache, dizziness and vertigo. In this study, we investigated the attenuation effect of sprouted peanut extract (SPE) on ethanol-induced hangover in male Sprague-Dawley rats. The animals were divided into five groups: the control group, which was administered ethanol only; the ethanol plus SPE experimental groups, which were administered ethanol and 100, 200, or 400 mg SPE/kg b.w.; and the positive control group, which was administered ethanol plus DAWN808$^{(R)}$, a commercial product. SPE-suspended water was delivered to rats via gavage 15 h and 30 min before the administration of ethanol. Blood was collected from the tail 0, 1, 3, and 5 h after ethanol administration. The results showed that serum ethanol concentrations were significantly lower in SPE treated groups than in the control group. Furthermore, hepatic alcohol and acetaldehyde dehydrogenase activities were enhanced by SPE in a dose dependent manner. These results suggest that SPE could be useful in attenuating hangover after alcohol consumption.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.3
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• pp.330-338
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• 2001

This paper is concerned with the effect of cylinder wakes upstream on blade characteristics of compressor cascade(NCA 65 series). At first, it is found that the velocity defect ratio of cylinder wake varies according to the acceleration and deceleration in a flow field but, is conserved nearly constant at flow downstream the cascade, irrespective of the flow path in the cascade. When a cylinder wake flows along near the suction surface of the blade, or impinges on the leading edge, the turbulent velocities are supplied on or inside the outer edge of boundary layer near the leading edge of suction surface, and the transition to a transitional or turbulent boundary layers is induced, so that the laminar separation is prevented, but the profile loss increases. The transition of boundary layer to a transitional or turbulent one is strongly related with the strength of added turbulent velocities near the leading edge on the suction surface, which is influenced by the flow path of a cylinder wake.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.3
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• pp.405-413
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• 2001

The present study investigates convective heat/mass transfer and flow characteristics inside a rotating two-pass rectangular duct. A naphthalene sublimation technique is employed to determine the detailed local heat transfer coefficients using the heat and mass transfer analogy. The objective of this study is to determine the effects of turning geometry with rotation for 0.0$\leq$Ro$\leq$0.24. The results reveal that the sharp-turn corner has the larger pressure drop and lower heat transfer in the post-turn region than those of the round-turn corner. The strong secondary flow enhances heat transfer for the round-turn corner. Coriolis force induced by the rotation pushes the high momentum core flow toward the trailing wall in the first passage with radially outward flow and toward the leading wall in the second passage with radially inward flow. Consequently, the high heat transfer rates are generated on the trailing surface and the leading surface in the first and second passage, respectively. However, the strong secondary flow due to the turning dominates the flow pattern in the second passage, thus the heat transfer differences between the leading and trailing surfaces are small with the rotation.

• Metals and materials international
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• v.24 no.6
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• pp.1403-1411
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• 2018

Graphene (multilayer graphene) was chosen as an additive to improve the hydrogen uptake and release properties of magnesium (Mg). Five weight percent of graphene was added to pre-milled Mg by milling in hydrogen (reaction-involving milling). The hydrogen uptake and release properties of the graphene-added Mg were investigated. The activation of Mg-5graphene, which was prepared by adding 5 wt% graphene to Mg pre-milled for 24 h, was completed after the second cycle (cycle number, CN=2). Mg-5graphene had a high effective hydrogen-storage capacity (the quantity of hydrogen absorbed for 60 min) of 6.21 wt% at CN=3 at 593 K in 12 bar $H_2$. At CN=1, Mg-5graphene released 0.46 wt% hydrogen for 10 min and 4.99 wt% hydrogen for 60 min. Milling in hydrogen is believed to create defects (leading to facilitation of nucleation), produce cracks and clean surfaces (leading to increase in reactivity), and decrease particle size (leading to diminution of diffusion distances or increasing the flux of diffusing hydrogen atoms). The added graphene is believed to have helped the sample have higher hydrogen uptake and release rates, weakly but partly, by dispersing heat rapidly.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.2
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• pp.467-479
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• 2022

Working memory (WM), which plays a vital role in daily activities, is a memory system that temporarily stores and processes information when people are engaged in complex cognitive activities. The influence of music on WM has been widely studied. In this work, we conducted a series of n-back memory experiments with different task difficulties and multiple trials on 14 subjects under the condition of no music and Alpha wave leading music. The analysis of behavioral data show that the change of music condition has significant effect on the accuracy and time of memory reaction (p<0.01), both of which are improved after the stimulation of Alpha wave music. Behavioral results also suggest that short-term training has no significant impact on working memory. In the further analysis of electrophysiology (EEG) data recorded in the experiment, auto-regressive (AR) model is employed to extract features, after which an average classification accuracy of 82.9% is achieved with support vector machine (SVM) classifier in distinguishing between before and after WM enhancement. The above findings indicate that Alpha wave leading music can improve WM, and the combination of AR model and SVM classifier is effective in detecting the brain activity changes resulting from music stimulation.

• Biomolecules & Therapeutics
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• v.31 no.2
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• pp.141-147
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• 2023

Antibiotic resistance has emerged as a global threat to modern healthcare systems and has nullified many commonly used antibiotics. β-Lactam antibiotics are among the most successful and occupy approximately two-thirds of the prescription antibiotic market. They inhibit the synthesis of the peptidoglycan layer in the bacterial cell wall by mimicking the D-Ala-D-Ala in the pentapeptide crosslinking neighboring glycan chains. To date, various β-lactam antibiotics have been developed to increase the spectrum of activity and evade drug resistance. This review emphasizes the three-dimensional structural characteristics of β-lactam antibiotics regarding the overall scaffold, working mechanism, chemical diversity, and hydrolysis mechanism by β-lactamases. The structural insight into various β-lactams will provide an in-depth understanding of the antibacterial efficacy and susceptibility to drug resistance in multidrug-resistant bacteria and help to develop better β-lactam antibiotics and inhibitors.

• Wind and Structures
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• v.38 no.3
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• pp.203-214
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• 2024

Large-span cantilevered roof represents a unique type of structure that is vulnerable to wind loads. Inspired by the need to maximumly reducing the rooftop wind loads, this study examined the feasibility of positioning vented slots on the leading edge, and the effectiveness of such aerodynamic mitigation measures are assessed via both physical and numerical simulations. The reliability of numerical simulation was evaluated via comparisons with the wind tunnel tests. The results indicated that, the variation of venting hole arrangement can cause significant change in the rooftop wind load characteristics. For the cases involved in this study, the maximum reduction of mean and peak wind suction coefficients are found to be 9% and 8% as compared to the original circular slot without venting holes. In addition, the effect of slot shape is also evident. It was shown that the triangular shaped slot tends to increase the wind suction near the leading edge, whereas the hexagonal and octagonal shaped slots are found to decrease the wind suction. In particular, with the installation of octagonal shaped slot, the maximum reduction of wind suction coefficients near the leading edge reaches up to 31% as compared to the circular shaped slot, while the maximum reduction of mean wind suction coefficients is about 30%.