• Journal of Veterinary Clinics
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• v.8 no.1
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• pp.1-10
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• 1991

The B-lymphocyte differentiation from committed B-cell progenitors to antibody-secreting cells was discussed. B-cell progenitors derived from hematopoietic stem cells undergo the rearrangement of immunoglobulin(Ig) gene. The earliest cells as B-cell precursors have cytoplasmic Is(${\mu}$ chain). The entire Is molecule is expressed on the surface after synthesis of L chain. The resting B cells(Go stage) stimulated by binding antigen via Ig-receptors are activated(G$_1$ stage) and followed by proliferation(S stage), coupled with further selection(affinity maturation. class switch). The production of antibody against a particular antigen depends on the activation of B cells with surface Is capable of reacting with that antigen. This process does not occur in isolation but is controlled by helper and suppressor T cells and antigen presenting cells(APC). The mechanism of T cell-dependent B-cell response for production of antibody is largely explained by the cell to cell cooperation and soluble helper factors of T cells. 1) The antigen specific B cells and helper T cells are linked by Is-receptors, leading to the delivery of helper signals to the B cells. 2) Helper T cells recognize the processed antigen-derived peptides with the MHC class II molecules(la antigen) and is stimulated to secrete B-cell proliferation and differentiation factors which activate B cells of different antigenic specificity. The two models are shown currently 1) At low antigen concentration, only the antigen-specific B cell binds antigen and presents antigen-derived peptides with la molecules to helper T cells, which are stimulated to secrete cytokines(IL-4, IL-5, etc.) and 2) At high antigen concentration, antigen-derived peptides are presented by specific B cells, by B cells that endocytose the antigens, as well as by APC Cytokines secreted from helper T cells also lead to the activation of B cells and even bystander B cells in the on- vironmment and differentiate them into antibody-secreting plasma cells.

• Journal of the Korea Convergence Society
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• v.11 no.8
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• pp.139-145
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• 2020

Due to the rapid development of computer technology, online learning using ICT technology is already quickly settling in our lives. Music education was conducted mainly in an offline-based environment, but research is being conducted to switch to online because there is no time and space constraint of online education and interactive education led by learners is possible. In this study, we propose design and implement an adaptive learning system to enable adaptive learning online among music education. This system has the following advantages. First, by providing an LMS-based platform, one can solve the social education problem corresponding to economic and geographical factors. Second, both objective learning feedback provided automatically by the online adaptive harmony learning system and teaching feedback. Third, learners can be provided with recommended answers to given harmony exercises. The adaptive online learning system of harmony will lead professors and learners to effectively teach and study.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.8
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• pp.1064-1069
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• 2014

The railway signalling system plays an essential role in the headway and routing control for a safe and efficient train operation. The reliable and safe operation of the system is very important because the failure of the railway signalling system can lead to the collision, derailment, or unexpected stop of a train. So far, the conventional wayside signal mode (ATS: Automatic Train Stop) has been generally used as the railway signalling system. However, this system is highly linked to a risk of major accidents resulted from human mistakes such as missing a signal or careless control of train speed. Accordingly, the onboard signal mode (ATC: Automatic Train Control) as an alternative of ATS has been recently introduced and applied to transmit effectively the information on speed control of a train by using computers and communication equipment. In the process of replacing the obsolete signal system, it is necessary to switch over the system while providing passengers with normal services. Therefore, the integration of a railway signaling system compatible for both ATS and ATC and its interface is discussed in this study. In particular, the implementation scenario required for operation planning of the integrated system was designed, and the results as well as effects of its applicability test were also presented.

• The Transactions of the Korea Information Processing Society
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• v.6 no.1
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• pp.182-192
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• 1999

The advance of the MPEG(Moving Picture Expert Group) and DSP(Digital Signal Processing) technologies lead the energence of the information appliances which are gradually digitalized and embedded the high-speed networking function. This paper proposes a CHANCE(Cost-effective Home ATM Network for the Consumer Electronics) protocol supporting the ATM-based high-speed networking between the information appliances within the home, and designs its specific functions including the network management and signalling function. The CHANCE protocol is basically based on the tree topology, and supports the plug-and-play function by using only the header field of the ATM cells. Unlike the existing ATM Warren protocol which uses the source routed addressing scheme to control the in-home devices from the Warren controller, the CHANCE protocol can support the inter-device controls as well as the controls from the CHANCE controller by using the switch and device identifier.

• Advances in concrete construction
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• v.5 no.2
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• pp.117-143
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• 2017

The attack of environmental aggressive agents progressively reduces the structural reliability of buildings and infrastructures and, in the worst exposition conditions, may even lead to their collapse in the long period. A change in the material and sectional characteristics of a structural element, due to the environmental damaging effects, changes its mechanical behaviour and varies both the internal stress redistribution and the kinematics through which it reaches its ultimate state. To identify such a behaviour, the evolution of both the damaging process and its mechanical consequences have to be taken into account. This paper presents a computational approach for the analysis of reinforced and prestressed concrete elements under sustained loading conditions and subjected to given damaging scenarios. The effects of the diffusion of aggressive agents, of the onset and development of the corrosion state in the reinforcement and the corresponding mechanical response are studied. As known, the corrosion on the reinforcing bars influences the damaging rate in the cracking pattern evolution; hence, the damage development and the mechanical behaviours are considered as coupled phenomena. The reliability of such an approach is validated in modelling the diffusion of the aggressive agents and the changes in the mechanical response of simple structural elements whose experimental behaviour is reported in Literature. A second set of analyses studies the effects of the corrosion of the tendons of a P.C. beam and explores potentially unexpected structural responses caused by corrosion under different aggressive exposition. The role of the different types and of the different positions of the damaging agents is discussed. In particular, it is shown how the collapse mode of the beam may switch from flexural to shear type, in case corrosion is caused by a localized chloride attack in the shear span.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.11
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• pp.5400-5418
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• 2016

Femtocells are envisioned as a key solution to embrace the ever-increasing high data rate and thus are extensively deployed. However, the dense and random deployments of femtocell access points (FAPs) induce severe intercell inference that in turn may degrade the performance of spectral efficiency. Hence, unrestrained proliferation of FAPs may not acquire a net throughput gain. Besides, given that numerous FAPs deployed in ultra-dense networks (UDNs) lead to significant energy consumption, the amount of FAPs deployed is worthy of more considerations. Nevertheless, little existing works present an analytical result regarding the optimal FAP density for a given User Equipment (UE) density. This paper explores the realistic scenario of randomly distributed FAPs in UDN and derives the coverage probability via Stochastic Geometry. From the analytical results, coverage probability is strictly increasing as the FAP-to-UE ratio increases, yet the growing rate of coverage probability decreases as the ratio grows. Therefore, we can consider a specific FAP-to-UE ratio as the point where further increasing the ratio is not cost-effective with regards to the requirements of communication systems. To reach the optimal FAP density, we can deploy FAPs in line with peak traffic and randomly switch off FAPs to keep the optimal ratio during off-peak hours. Furthermore, considering the unbalanced nature of traffic demands in the temporal and spatial domain, dynamically and carefully choosing the locations of active FAPs would provide advantages over randomization. Besides, with a huge FAP density in UDN, we have more potential choices for the locations of active FAPs and this adds to the demand for a strategic sleeping policy.

• Journal of the Korea Society of Computer and Information
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• v.12 no.3
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• pp.147-153
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• 2007

Task scheduling is an essential part of any computer system for allocating tasks to a processor of the system among various competitors. As we know, in real-time system, the failure of scheduling a hard real-time task my lead to disastrous consequence. Besides efficiency, resource and speed, real-time system has to take time constraint in serious consideration. This paper proposes a priority-driven scheduling algorithm for real-time multiprocessor system. which is called L-RE coordinates algorithm. L-RE coordinates is a new way of describing the task scheduling problem. In the algorithm, we take both deadline and laxity into consideration for allocating the priority. The simulation result shows that the new algorithm is viable and performance better than EDF and LLF algorithm on schedulability and context switch respectively.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.8A
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• pp.569-580
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• 2003

One of the important advantages of multichannel switches is the incorporation of inherent fault tolerance into the switching fabric. For example, if a link which belongs to the multichannel group fails, the remaining links can assume responsibility for some of the traffic on the failed link. On the other hand, if faults occur in the switching elements, it can lead to erroneous routing and sequencing in the multichannel switch. We investigate several fault localization algorithms in multichannel crossbar ATM switches with a view to early fault recovery, The optimal algorithm gives the best performance in terms of time to localization but is computationally complex which makes it difficult to implement. We develop an on-line algorithm which is computationally mote efficient than the optimal algorithm. We evaluate its performance through simulation. The simulation results show that performance of the on line algorithm is only slightly sub-optimal for both random and bursty traffic. Finally a fault recovery algorithm is described which utilizes the information provided by the fault localization algorithm.

• The KIPS Transactions:PartD
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• v.17D no.6
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• pp.453-462
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• 2010

The switch from analog to digital broadcast television is extended rapidly. The DTV can offer multiple programming choices, interactive capabilities and so on. Moreover, with the spread of Internet, the information exchange between the communities is increasing, too. These facts lead to the new TV service environment which can offer customized TV programs to personal/community users. This paper proposes a 'Customized Digital TV System for Individuals/Communities based on Data Stream Mining' which can analyze user's pattern of TV watching behavior. Due to the characteristics of TV program data stream and EPG(electronic program guide), the data stream mining methods are employed in the proposed system. When a user is watching DTV, the proposed system can control the surrounding circumstances as using the user behavior profiles. Furthermore, the channel recommendation system on the smart phone environment is proposed to utilize the profiles widely.

• Journal of Service Research and Studies
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• v.8 no.3
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• pp.37-49
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• 2018

In this study, we conducted an exploratory study for designing service science as a degree program that will lead the 21st century. In the new era, the convergence of industries is accelerating and the mobility of the profession is greatly increased, so the talents to be trained in higher education will be greatly changed. We must cultivate human resources capable of creating their own jobs through competency development and cultivate talented individuals who can demonstrate creative initiative in the ecosystem where the boundaries between industries are dismantled. To this end, it is required to switch from the existing vertical majors and systems to horizontal majors, and service majors are expected to play a key role in this transition. In this study, we designed the service science degree program reflecting the changes of the new economy and reflecting the demand of the new education. The service science curriculum provides an analysis as it can award a degree as an independent major, or may serve as a sub-major or an associate major with existing majors. Service studies are expected to play the most effective role in cultivating the capabilities defined by the 21st century human resources in the World Economic Forum.