• Journal of Korean Society of Coastal and Ocean Engineers
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• v.27 no.1
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• pp.38-49
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• 2015

Past study of tsunami heavily relied on the numerical modelling using 2D Boussinesq Eq. and Solitary wave. Lately, based on the fact that numerically simulated run up heights based on solitary wave are somewhat smaller than the measured one, Leading Depression N (LDN) Wave has been elaborated, which can account the advancement of a shore line before tsunami strikes a shore. Thereafter it is reported that more accurate simulation can be possible once LDN is deployed. On the other hand, there were numerous reports indicating that stable LDN wave can't be sustained in the hydraulic model test. These conflicts between the hydraulic model tests and numerical results have their roots on the assumption made in the derivation of Boussinesq type wave model such as that wave nonlinearity is equally balanced with wave dispersiveness. Hence, in the numerical simulation based on the Boussinesq type wave model, wave dispersiveness is inevitably underestimated, especially in deep water. Based on this rationale, we developed the modified methodology for the generation of stable LDN wave in the 3D numerical wave flume, and proceeded to numerically analyze the depression effect of Hybrid Breaker on the run up height due to tsunami using the Navier Stoke Equation. The verification of newly proposed wave model in this study was carried out using the run up height from the hydraulic model test. It was shown that Hybrid Breaker consisting of three water chamber and slope at its front can reduce 13% of run up height for H = 5m, and 10% of run up height for H = 6m.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.296-299
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• 2006

This study is about correlation between WECPNL and other units such as NNI, Leq and Ldn for aircraft noise that ere measured by automatic measuring system networks for grasping the effect of aircraft noise and investigated the aircraft noise level from 2004 to 2005 nearby 10 airports in Korea. It is very important to find the relationship among the various noise units, because exchange between the results of many other nation's study can improve the assessment and mitigation study of the aircraft noise. Correlation between WECPNL and M is better than one between WECPNL and Leq and between WECPNL and Ldn, because WECPNL and NNI are based on the PNL.

• The Bulletin of The Korean Astronomical Society
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• v.24 no.1
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• pp.56-56
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• 1999

• Journal of Energy Engineering
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• v.9 no.1
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• pp.1-9
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• 2000

공정연계를 최소호하는 IGCC 시스템에 대한 개념설계를 수행하였다. 공정분석은 상용코드인 ASPEN PLUS를 이용하였다. 가스화기의 적절한 운전조건을 찾기위하여 가스화기를 경계조건으로 하는 액서지 민감도분석을 통하여 투입되는 슬러리와 산소의 조건을 결정하였다. 또한 , 생성가스 냉각시 현열을 최대한 회수학 ldn하여 , 열교환망을 통하여 급수를 에열하고 가스화플랜트의 각 부분에 공급하도록 공정을 구성하였다. 여분의 가열된 급수는 갑압증발시켜 복합사이클에서 동력을 생성시키는데 사용되어진다. 이와 같은 시스템은 , 가스터빈 -ASU-가스화플랜트의 공기에 의한 공정연계와, HRSG-가스냉각 및 정제시스템 간의 증기연계를 가능한 적게함으로써 공정의 운전성과 경제성을 최적으로 유지할 수 있다. 본 연구에서 제시하는 공정의 경우에, 열효율이 약 39%(고위발열량 기준)으로 나타났으며, 단위 기기 및 단위공정들의 최적화를 통하여 40%의 효율달성이 가능할 것이다.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.87-88
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• 2015

We present results of our R-band polarimetry of a bright-rimmed cloud, IC1396A (with BRC 36), associated with the H II region S131 and the cometary globule LDN 1616 to study their magnetic field geometry. The distances of these clouds have been reported to be ~ 750 pc and ~ 450 pc, respectively in the literature. The young open cluster Trumpler 37 in the vicinity of IC1396A and the high mass stars in the Orion belt near L1616 are found to be responsible for the structure of these clouds. We made polarimetry of foreground stars inferred from their distances measured by the Hipparcos satellite to subtract the foreground contribution to the observed polarization results. We discuss the optical polarimetric results and compare our findings with MHD simulations towards BRCs and CGs.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.3
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• pp.197-206
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• 2021

Carnosol is a phenolic diterpene phytochemical found in rosemary and sage with reported anti-microbial, anti-oxidant, anti-inflammatory, and anti-carcinogenic activities. This study aimed to investigate the effect of carnosol on the lineage commitment of mouse bone marrow-derived mesenchymal stem cells (mBMSCs) into osteoblasts and adipocytes. Interestingly, carnosol stimulated the early commitment of mBMSCs into osteoblasts in dose-dependent manner as demonstrated by increased levels of alkaline phosphatase activity and Alizarin red staining for matrix mineralization. On the other hand, carnosol significantly suppressed adipogenesis of mBMSCs and downregulated both early and late markers of adipogenesis. Carnosol showed to induce osteogenesis in a mechanism mediated by activating BMP signaling pathway and subsequently upregulating the expression of BMPs downstream osteogenic target genes. In this context, treatment of mBMSCs with LDN-193189, BMPR1 selective inhibitor showed to abolish the stimulatory effect of carnosol on BMP2-induced osteogenesis. In conclusion, our data identified carnosol as a novel osteoanabolic phytochemical that can promote the differentiation of mBMSCs into osteoblasts versus adipocytes by activating BMP-signaling.

• International Journal of Oral Biology
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• v.42 no.4
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• pp.191-196
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• 2017

Transglutaminase2 (TGM2) is a multi-functional calcium dependent enzyme that affects angiogenesis, apoptosis, differentiation, attachment, and changes in the extracellular matrix. However, its function in periodontal tissue has not yet been studied. The aim of this study was to investigate the association of the TGM2 expression and the modulation of inflammatory mediators in inflamed periodontal ligament (PDL) cells induced by pro-inflammatory cytokines such as Interleukin-$1{\beta}$ and the Tumor necrosis $factor-{\alpha}$. The expression of TGM2 was increased in the inflamed periodontal tissue and PDL cells. Over-expressed TGM2 in the PDL cells increased expression of MMP1, MMP3, IL-6, CXCL8, and PTGS2. Conversely, inhibition of TGM2 activity using LDN27219, a TGM2 inhibitor, resulted in decreased expression of MMP1, MMP3, IL-6, and CXCL8. The mRNA expression was confirmed by RT-PCR and quantified by qRT-PCR. Protein levels were also confirmed by immunofluoroscence staining. These results suggest that TGM2 plays an important role in the regulation of inflammatory mediators which exacerbate tissue damage in inflamed periodontal tissue.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.7
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• pp.86-92
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• 2015

This study proposes new LDP code to improve facial expression recognition rate by including local directional number(LDN), edge magnitudes and differences of neighborhood edge intensity. LDP is less sensitive on the change of intensity and stronger about noise than LBP. But LDP is difficult to express the smooth area without changing of intensity and if background image has the similar pattern with a face, the facial expression recognition rate of LDP is low. Therefore, we make the LDP code has the local directional number and the edge strength and experiment the facial expression recognition rate of changed LDP code.