• Proceedings of the Korean Society for Bioinformatics Conference
• /
• 2003.10a
• /
• pp.26-51
• /
• 2003

Large scale protein interaction maps provide a new, global perspective with which to analyse protein function. PSIMAP, the Protein Structural Interactome Map, is a database of all the structurally observed interactions between superfamilies of protein domains with known three-dimensional structure in thePDB. PSIMAP incorporates both functional and evolutionary information into a single network. It makes it possible to age protein domains in terms of taxonomic diversity, interaction and function. One consequence of it is to predict the most important protein domain structure in evolution. We present a global analysis of PSIMAP using several distinct network measures relating to centrality, interactivity, fault-tolerance, and taxonomic diversity. We found the following results: ${\bullet}$ Centrality: we show that the center and barycenter of PSIMAP do not coincide, and that the superfamilies forming the barycenter relate to very general functions, while those constituting the center relate to enzymatic activity. ${\bullet}$ Interactivity: we identify the P-loop and immunoglobulin superfamilies as the most highly interactive. We successfully use connectivity and cluster index, which characterise the connectivity of a superfamily's neighbourhood, to discover superfamilies of complex I and II. This is particularly significant as the structure of complex I is not yet solved. ${\bullet}$ Taxonomic diversity: we found that highly interactive superfamilies are in general taxonomically very diverse and are thus amongst the oldest. This led to the prediction of the oldest and most important protein domain in evolution of lift. ${\bullet}$ Fault-tolerance: we found that the network is very robust as for the majority of superfamilies removal from the network will not break up the network. Overall, we can single out the P-loop containing nucleotide triphosphate hydrolases superfamily as it is the most highly connected and has the highest taxonomic diversity. In addition, this superfamily has the highest interaction rank, is the barycenter of the network (it has the shortest average path to every other superfamily in the network), and is an articulation vertex, whose removal will disconnect the network. More generally, we conclude that the graph-theoretic and taxonomic analysis of PSIMAP is an important step towards the understanding of protein function and could be an important tool for tracing the evolution of life at the molecular level.

• Journal of vocational education research
• /
• v.37 no.1
• /
• pp.139-156
• /
• 2018

This study analyzed the aspect of occupational contents shown in total 24 types of Technology & Home Economics (1). (2) textbooks for middle school in accordance with the 2009 revised curriculum. Analyzing the type of occupation shown in textbooks based on the Korean Standard Classification of Occupations(hierarchical classification), the frequency(ratio), and the aspect of occupational contents in each unit of textbooks and each data type, this study provided basic data to be able to understand diverse aspects of occupational contents. In the results of study, in case of Technology & Home Economics textbooks for middle school, the large area of 'home life' presented occupational contents in the relatively high ratio than the 'world of technology' while the frequency(ratio) of occupational contents was very much different in each publisher, large area, and unit. The occupation name presented in textbooks provided very limited information in the level of 5.27% of occupations presented in the Korea Dictionary of Occupations. Especially, providing occupational information concentrated in professionals & relevant practiceans in the type of the Korean Standard Classification of Occupations(hierarchical classification), it was limited to provide opportunities to learn the diversity related to occupation. Based on such results of study, on top of introducing diverse occupational contents to make students cherish all the occupations, it would be also necessary to seek for institutional measures related to textbook development/career education, so that they could explore career by considering their aptitude and interest.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.55 no.4
• /
• pp.449-454
• /
• 2022

The oxygen consumption rate (OCR) based on the water temperature and body size of the sea squirt Halocynthia roretzi was examined to provide quantitative information about the metabolic response of the species. OCRs were measured using a closed flow-through respirometer at four different water temperatures (10, 15, 20 and 25℃) and two different body sizes (21.4±1.1 g and 150.5±1.3 g, wet weight) with triplicates of each treatment. OCR increased as water temperature increased at both body sizes, but decreased as body size increased regardless of the water temperature (P<0.001). The effect of body size evaluated as a power function ranged from 0.8055 to 0.8884. The highest Q₁₀ values in the small and large size groups ranged from 15 to 20℃ and 20 to 25℃, respectively. The metabolic daily energy loss rate via respiration at all tested temperatures ranged from 56.2 to 106.1 J g^-1 d^-1 in the small-size group and from 44.5 to 92.0 J g^-1 d^-1 in the large-size group. Our results indicate that the metabolic response of H. roretzi highly depends on fluctuating water temperature at a given life stage.

• Journal of Animal Science and Technology
• /
• v.53 no.1
• /
• pp.29-34
• /
• 2011

Using the materials collected from nine farms in a three-way cross system to produce commercial pigs produced from F1 sows (Landrace $\times$ Large White) $\times$ Duroc, the power of individual discrimination and parentage of the 13 microsatellite (MS) marker set that has been suggested for individual/brand identification (traceability) was empirically tested. Initially, genotypes of the parental population ($F_1$ sows and Duroc), and commercial pigs were determined and the genotype frequency and polymorphic index were estimated using the Cervus 2.0 program. The probability of identity among genotypes of random individuals, that random half sibs and that of full sib individuals, based on the genotypes from 91 $F_1$ sows and Duroc were expected to be $4.94{\times}10^{-34}$, $8.16{\times}10^{-23}$ and $2.01{\times}10^{-08}$, respectively, using the API-CALC version 1.0 program. When commercial pigs were included, the estimates increased to $3.74{\times}10^{-35}$, $5.48{\times}10^{-25}$ and $2.96{\times}10^{-11}$, respectively. For the empirical verification of the estimated powers of individual discrimination and parentage, the parentage test was performed for 452 commercial pigs using PAPA version 2.0, and individuals with the same genotype were investigated using the Cervus version 2.0 program. Parents for all commercial pigs were successfully estimated and no identical individual was identified in the pedigree. Although the individual discriminating power was not fully verified because of the lack of individuals corresponding with the theoretical power, the 100% efficiency of parentage test was clearly confirmed. Therefore, we believe that the 13 MS marker set in conjunction with management record/information for the pig production kept in a farm/brand should be useful in the pork traceability in a brand unit.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.51 no.6
• /
• pp.276-281
• /
• 2014

Necessities of a traffic means work a car in the modern society human to an usability of a life is enjoying. On the other hand, the damage by traffic accident increment the human quotient worked as we were in proportion to the vehicle which increased. Passing an examination moves necessarily on an obstacle to suddenly appear at the fronts if a car travels and the vehicles which stopped suddenly. Dynamic passing an examination about an obstacle turn on Vehicle Emergency Lamp to by hand when is unhurried, and can turn off, but to appear urgently dynamic passing an examination in time human is instinctive, but cannot inform an emergency to a back vehicle, and a rear-end collision occurs. A car we synthesize a speed of a vehicle, and this unit analyzes as we use GPS, and to drive runs Vehicle Emergency Lamp to automatic in the situations that shall turn on emergencies etc. If a speed of a vehicle continuously slows down in too high-speed driving or low-speed driving, or we are stopped, Vehicle Emergency Lamp is always turned on. It was built if we rise again as clearing itself from risk, and a speed of a vehicle judges, and we turn off Vehicle Emergency Lamp to automatic. It runs till rear-end collision sensor operates, and by hand reset does Vehicle Emergency Lamp a driving vehicle collides from behind to a back vehicle or when a driving vehicle was overthrown. It is shortened very much to the chain rear-end collision traffic accident that is a traffic accident of large size if we use this unit. And we did authentication through the experiment which a driver was helpful to unnecessary operation and a relaxed safe driving during drivings.

• Journal of Bio-Environment Control
• /
• v.31 no.3
• /
• pp.246-254
• /
• 2022

Domestic facility agriculture grows rapidly, such as modernization and large-scale. And the production scale increases significantly compared to the area, accounting for about 60% of the total agricultural production. Greenhouses require energy input to create an appropriate environment for stable mass production throughout the year, but the energy load per unit area is large because of low insulation properties. Through the rooftop greenhouse, one of the types of urban agriculture, energy that is not discarded or utilized in the building can be used in the rooftop greenhouse. And the cooling and heating load of the building can be reduced through optimal greenhouse operation. Dynamic energy analysis for various environmental conditions should be preceded for efficient operation of rooftop greenhouses, and about 40% of the solar energy introduced in the greenhouse is energy exchange for crops, so it should be considered essential. A major analysis is needed for each sensible heat and latent heat load by leaf surface temperature and evapotranspiration, dominant in energy flow. Therefore, an experiment was conducted in a rooftop greenhouse located at the Korea Institute of Machinery and Materials to analyze the energy exchange according to the growth stage of crops. A micro-meteorological and nutrient solution environment and growth survey were conducted around the crops. Finally, a regression model of leaf temperature and evapotranspiration according to the growth stage of leafy vegetables was developed, and using this, the dynamic energy model of the rooftop greenhouse considering heat transfer between crops and the surrounding air can be analyzed.

• Journal of Families and Better Life
• /
• v.26 no.5
• /
• pp.195-209
• /
• 2008

The purpose of this study was to provide basic information about design guidelines of activity areas in elderly nursing facilities. For the study, the activity areas of 44 facilities in Korea were investigated to categorize their spatial compositions and forms, and then a case study about 19 facilities was conducted to analyse their hierarchical characteristics. The results of the study were as follows: First, the major type of spatial composition among 44 research facilities was concentration, but compartment type was the main among unit-care facilities. By the year, all the types of spatial composition were evenly distributed during recent five years, while concentration type was about 40% before 2003. Second, the major form of activity areas was hall or corridor extension for large group. But there was more alcove or separation form among small group spaces. Third, in the case analysis about hierarchical characteristics, hall and corridor extension form met the requirements of accessibility and openness of public and semi-public areas. On the other hand, separation form had a problem in satisfying both requirements. The semi-private areas, which were around the elderly bedrooms and the elderly were able to watch activities in, were not sufficient in many facilities. Fourth, the division of public and semi-public area was mainly by furniture, and the individuality of semi-private area was defined by dead-end place and corner seats of the window or the corridor. The diversity of semi-private area was likely to be appeared in connection or distribution type. On the basis of the results, the basic design guidelines for activity areas in elderly nursing facilities could be suggested as follows: On the whole, connection or distribution type in spatial composition is more efficient for hierarchical flow than concentration or compartment type is, especially in Korean facilities having many elderly residents per floor. In detail, the design of public and semi-public area should be focused on their openness and accessibility. The recommended forms of activity areas were hall or corridor extension in public area, and living room, corridor extension, or large corridor in semi-public area to effectively function as large or small group spaces. In semi-private areas, the spatial diversity and individuality should be considered.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.15 no.6
• /
• pp.187-193
• /
• 2015

The ICT healing platform sets a couple of goals including preventing chronic diseases and sending out early disease warnings based on personal information such as bio-signals and life habits. The 2-step open system(TOS) had a relay designed between the healing platform and the storage of personal health data. It also took into account a publish/subscribe(pub/sub) service based on large-scale connections to transmit(monitor) the data processing process in real time. In the early design of TOS pub/sub, however, the same buffers were allocated regardless of connection idling and type of message in order to encode connection messages into a deflate algorithm. Proposed in this study, the dynamic buffer allocation was performed as follows: the message transmission type of each connection was first put to queuing; each queue was extracted for its feature, computed, and converted into vector through tf-idf, then being entered into a k-means cluster and forming a cluster; connections categorized under a certain cluster would re-allocate the resources according to the resource table of the cluster; the centroid of each cluster would select a queuing pattern to represent the cluster in advance and present it as a resource reference table(encoding efficiency by the buffer sizes); and the proposed design would perform trade-off between the calculation resources and the network bandwidth for cluster and feature calculations to efficiently allocate the encoding buffer resources of TOS to the network connections, thus contributing to the increased tps(number of real-time data processing and monitoring connections per unit hour) of TOS.

• Korean Journal of Digital Imaging in Medicine
• /
• v.16 no.1
• /
• pp.43-47
• /
• 2014

Sens of insecutity of the public and professionals about harmful effects of radiation is increasing in an accident at the Chernobyl and Fkushima nuclear power plant.Anxiety was amplified to lack of information about radiation majority of people. To target the middle and high school in the region of Daegu and Gyeongsangbuk-do, to investigate the radiation recognition of the next generation, it is intended to present a model of education for the safe use of radiation. The High School of the six metropolitan cities, city, town through the questionnaire and needs to be educational experience of radiation and use knowledge level of radiation, experience in daily life, understanding of man-made radiation and natural radiation, information channel on radiation, the radiation Distribute the total 800 parts of, to recover the 629 unit, was analyzed for 155 females 474 males. Many people 75.36% of the people, to 24.64% female subjects of this investigation, was constant, respectively from 13 to 18 years age. It is a large number and 30.37% of the respondents as "normal" level of knowledge of radiation, for the type of radiation, most knew. You have answer for risk experience of the medical radiation was higher, touching a lot of information via the broadcast medium in general, and the accuracy is low. I thought we wanted to be educated three or more twice a year, as an educator,about 71.37% and radiation-related understanding of knowledge and background in accordance with the diversification of information channels, the regional differences between urban and rural areas. But I considered the difference age (grade) for each is displayed, intended for junior high school students, the target surface and use the occurrence of radiation, high school students, the need for education about risk and application of radiation through this study.

• Journal of Internet Computing and Services
• /
• v.5 no.5
• /
• pp.1-15
• /
• 2004

In this paper, we explain the design and implementation of GWB(Gene WorkBench), which is a web-based, integrated system for efficiently managing and analyzing genomic sequences, Most existing software systems handling genomic sequences rarely provide both managing facilities and analyzing facilities. The analysis programs also tend to be unit programs that include just single or some part of the required functions. Moreover, these programs are widely distributed over Internet and require different execution environments. As lots of manual and conversion works are required for using these programs together, many life science researchers suffer great inconveniences. in order to overcome the problems of existing systems and provide a more convenient one for helping genomic researches in effective ways, this paper integrates both managing facilities and analyzing facilities into a single system called GWB. Most important issues regarding the design of GWB are how to integrate many different analysis programs into a single software system, and how to provide data or databases of different formats required to run these programs. In order to address these issues, GWB integrates different analysis programs byusing common input/output interfaces called wrappers, suggests a common format of genomic sequence data, organizes local databases consisting of a relational database and an indexed sequential file, and provides facilities for converting data among several well-known different formats and exporting local databases into XML files.