• 제목/요약/키워드: Laboratory animals

검색결과 844건 처리시간 0.031초

백선 환자가 사육하고 있는 애완동물 및 침실먼지에서 피부사상균의 분리 (Isolation of Dermatophytes from Domestic Animals and Bed Room Dust of Tinea Patients)

  • 방용준;김쌍용
    • 대한임상검사과학회지
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    • 제38권2호
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    • pp.94-98
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    • 2006
  • The mattresses and dust in the bed rooms of nine dermatophytes infected patients and nine domestic animals were examined by the KOH method. Microsporum canis species and Trichophyton mentagrophytes were isolated from cats and rabbits, respectively. The sources of infection of three patients were the M. canis infected cats raised by them and the four other patient's sources of infection were not confirmed. The sites of infection of the nine patients were their heads and those of the domestic animals were their heads and bodies. M. canis species were isolated from the infection sites of three cats and specimens collected by hair brush from the nine domestic animals. T. mentagrophytes species were also isolated from the infection sites of two rabbits. The seven patients had mattresses and bed room dust contaminated with M. canis.

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기종저(氣腫疽)에 대(對)한 몇가지 항생물질(抗生物質) 치료시험(治療試驗) (STUDIES ON THE EFFECT OF ANTIBIOTIC TREATMENT FOR BLACKLEG)

  • 김동성;차연호
    • 대한수의학회지
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    • 제4권1호
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    • pp.27-33
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    • 1964
  • In the treatment of mice Aureomycin, Oil penicillin, Achromycin, Ambrasynth and Terramycin were effective on the Black-leg disease when they were administered about 4 to 5 hours before the death of control animals. Synthomycetin, however, was observed to be effective when administered 8 hours or more before the control death. Streptomycin seemed to be rather less effective than Black leg antiserum. It was not effective at all when given 19 hours before the death of control animal although there was a delay of taking death by 5 hours in the treated group. As was in mice, Streptomycin was little effective in the treatment of calves, while other antibiotics showed fine efficacy on the diseased animals. The diseased animals, when given with anitibiotics 37 hours before the death of control showed the rise of temperature($41^{\circ}C$ or more), swelling and redness on the site of infection and then recovcred to normal stage. In the treatment of calves, Aureomycin only delayed the taking death of the deseased animals by 111 hours when administered 4 hours before the death of control animals. And other antibiotics, when given 4 hours before the death of control animals were effective, although the deseased animls developed symptoms such as hard breathing, anorexia and dropsical swellings. Oil penicillin was observed to be comparatively larger in its efficacy on the treatment of Black leg disease.

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독도 주변 해역에 서식하는 중형저서생물 (Marine Meiobenthic Faunal Communities of the Sediments near Dokdo in the East Sen, Korea)

  • 김동성;민원기;김웅서
    • Ocean and Polar Research
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    • 제24권4호
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    • pp.419-427
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    • 2002
  • Meiobenthic community structure near Dokdo was investigated during two survey periods of June, 1999 and October 2000. Meiobenthos were separated from the sediment core samples collected from eight stations. A total of 19 meiobenthic animal groups were identified from those core samples. The most abundant meiobenthic animals belonged to Phylum Nematoda in both seasons and all stations. Sarcomastigophorans, nauplius of crustaceans, and benthic harpactiocoids were the next abundant meiobenthos. Vertical distribution of meiobenthic animals showed the highest individual numbers in the surface sediment layers of 0-1cm depth with a steep decreasing trend with depth for the three sampling stations (A0, A9', A19) located in the continental slope. Horizontal distribution of meiobenthic animals for the study area near Dokdo showed lower density at the sampling stations near Dokdo and the lowest density of meiobenthos in A19 (depth-2261 m). For size distribution, analysis showed that animals which fit onto the mesh size of 0.125mm were abundant. This study suggested that the continental shelf near Dokdo have a more unstable environment fo meiobenthos than the continental slope.

Retinopathy Induced by Zinc Oxide Nanoparticles in Rats Assessed by Micro-computed Tomography and Histopathology

  • Kim, Young Hee;Kwak, Kyung A;Kim, Tae Sung;Seok, Ji Hyeon;Roh, Hang Sik;Lee, Jong-Kwon;Jeong, Jayoung;Meang, Eun Ho;Hong, Jeong-sup;Lee, Yun Seok;Kang, Jin Seok
    • Toxicological Research
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    • 제31권2호
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    • pp.157-163
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    • 2015
  • Nanotechnology has advanced at an extremely rapid pace over the past several years in numerous fields of research. However, the uptake of nanoparticles (NPs) into the body after administration through various routes may pose a risk to human health. In this study, we investigated the potential ocular toxicity of 20-nm, negatively- charged zinc oxide (ZnO) NPs in rats using micro-computed tomography (micro-CT) and histopathological assessment. Animals were divided into four groups as control group, ZnO NPs treatment group (500 mg/kg/day), control recovery group, and ZnO NPs treatment and recovery group. Ocular samples were prepared from animals treated for 90 days (10 males and 10 females, respectively) and from recovery animals (5 males and 5 females, respectively) sacrificed at 14 days after final treatment and were compared to age-matched control animals. Micro-CT analyses represented the deposition and distribution of foreign materials in the eyes of rats treated with ZnO NPs, whereas control animals showed no such findings. X-ray fluorescence spectrometry and energy dispersive spectrometry showed the intraocular foreign materials as zinc in treated rats, whereas control animals showed no zinc signal. Histopathological examination revealed the retinopathy in the eyes of rats treated with ZnO NPs. Neuronal nuclei expression was decreased in neurons of the ganglion cell layer of animals treated with ZnO NPs compared to the control group. Taken together, treatment with 20-nm, negatively-charged ZnO NPs increased retinopathy, associated with local distribution of them in ocular lesions.

Effect of Imported Young Bulls with Higher Genetic Merit on Genetic Progress of Japanese Holstein Population

  • Terawaki, Y.;Shimizu, H.;Fukui, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제10권4호
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    • pp.416-421
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    • 1997
  • The effect of imported young bulls on the genetic progress was examined in the Holstein dairy cattle population in Japan. The effect of the difference of mean genetic merit between imported and domestic young bulls ("genetic difference") was recognized on the genetic progress of the domestic animals in the early stage of selection. On the other hand, the genetic progress of domestic animals were remarkably influenced by the genetic trend of imported young bulls ("genetic trend") in the later stage. Import of young bulls originated from high genetic level of young bulls originated from high genetic level population improved the genetic progress of domestic population. But, the increase of the immigration ratio of imported young bulls ("immigration ratio") did not influence linearly on the progress of the genetic merit of domestic animals. Even if "immigration ratio" was 100%, the genetic merit of domestic animals could not overcome the one of imported young bulls. In the later stage of selection, the genetic merit of domestic animals ran parallel to those of imported young bulls.

Identification of long non-coding RNA-mRNA interactions and genome-wide lncRNA annotation in animal transcriptome profiling

  • Yoon-Been Park;Jun-Mo Kim
    • Journal of Animal Science and Technology
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    • 제65권2호
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    • pp.293-310
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    • 2023
  • Protein-translated mRNA analysis has been extensively used to determine the function of various traits in animals. The non-coding RNA (ncRNA), which was known to be non-functional because it was not encoded as a protein, was re-examined as it was studied to actually function. One of the ncRNAs, long non-coding RNA (lncRNA), is known to have a function of regulating mRNA expression, and its importance is emerging. Therefore, lncRNAs are currently being used to understand the traits of various animals as well as human diseases. However, studies on lncRNA annotation and its functions are still lacking in most animals except humans and mice. lncRNAs have unique characteristics of lncRNAs and interact with mRNA through various mechanisms. In order to make lncRNA annotations in animals in the future, it is essential to understand the characteristics of lncRNAs and the mechanisms by which lncRNAs function. In addition, this will allow lncRNAs to be used for a wider variety of traits in a wider range of animals, and it is expected that integrated analysis using other biological information will be possible.

Oil supplementation improved growth and diet digestibility in goats and sheep fed fattening diet

  • Candyrine, Su Chui Len;Jahromi, Mohammad Faseleh;Ebrahimi, Mahdi;Chen, Wei Li;Rezaei, Siamak;Goh, Yong Meng;Abdullah, Norhani;Liang, Juan Boo
    • Asian-Australasian Journal of Animal Sciences
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    • 제32권4호
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    • pp.533-540
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    • 2019
  • Objective: This study evaluated the growth, digestibility and rumen fermentation between goats and sheep fed a fattening diet fortified with linseed oil. Methods: Twelve 3 to 4 months old male goats and sheep were randomly allocated into two dietary treatment groups in a $2(species){\times}2$ (oil levels) factorial experiment. The treatments were: i) goats fed basal diet, ii) goats fed oil-supplemented diet, iii) sheep fed basal diet, and iv) sheep fed oil-supplemented diet. Each treatment group consisted of six animals. Animals in the basal diet group were fed with 30% alfalfa hay and 70% concentrates at a rate equivalent to 4% of their body weight. For the oil treatment group, linseed oil was added at 4% level (w:w) to the concentrate portion of the basal diet. Growth performance of the animals was determined fortnightly. Digestibility study was conducted during the final week of the feeding trial before the animals were slaughtered to obtain rumen fluid for rumen fermentation characteristics study. Results: Sheep had higher (p<0.01) average daily weight gain (ADG) and better feed conversion ratio (FCR) than goats. Oil supplementation did not affect rumen fermentation in both species and improved ADG by about 29% and FCR by about 18% in both goats and sheep. The above enhancement is consistent with the higher dry matter and energy digestibility (p<0.05), as well as organic matter and neutral detergent fiber digestibility (p<0.01) in animals fed oil- supplemented diet. Sheep had higher total volatile fatty acid production and acetic acid proportion compared to goat. Conclusion: The findings of this study suggested that sheep performed better than goats when fed a fattening diet and oil supplementation at the inclusion rate of 4% provides a viable option to significantly enhance growth performance and FCR in fattening sheep and goats.

Identification of a norovirus from diarrheic dog in Gwangju, Republic of Korea

  • Ba-Ra-Da Koh;Su-Yeon Seo;Ga-Hoi Choi;Byeong-Cheol Yoon
    • 한국동물위생학회지
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    • 제46권3호
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    • pp.235-241
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    • 2023
  • Noroviruses are a major cause of gastroenteritis in humans and animals worldwide. In 2021, canine norovirus (CNoV) infection was detected at an animal clinic in Gwangju area, South Korea. A semi-nested polymerase chain reaction was developed to amplify a 478 bp fragment of the RdRp gene of CNoV. The phylogenetic analysis of this fragment confirmed the strain to be genogroup IV.2 (Dog/GIV.2/gw/s377/2021/KOR), which exhibited the highest similarity to the feline NoV strain GIV.2/CU081210E/USA/2010 (accession no. NC_045762) with 95.1% nucleotide (nt) identity and 98.7% amino acid (aa) identity. These research findings indicate that the detected norovirus in dogs is genetically similar to a feline-origin norovirus, suggesting easy cross-species transmission among animals.