• Title/Summary/Keyword: LU3

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Discussion on the Route of Lung Meridian: Focus on LU3 and LU4 (수태음폐경 노선에 대한 고찰: 천부·협백을 중심으로)

  • Seok Mo, Song
    • Korean Journal of Acupuncture
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    • v.39 no.4
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    • pp.172-183
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    • 2022
  • Objectives : An error was found in the recent standard by the World Health Organization (WHO) on the locations of the Upper arm Route of Lung Meridian (URLM) and its acupoints LU3 and LU4. This possible incorrect information is being taught throughout Korean medicine colleges nationwide, which follow WHO standards. Therefore, an investigation is required to sort out this discrepancy based on the evidence in historical documents. Methods : The location of WHO's URLM and LU3 and LU4 were compared with corresponding information in the classical literature. The anatomical structure mentioned in these classical documents was examined. Finally, an assessment was conducted on whether this structure is reflected in the WHO standards. Results : Classical literature prior to the early 20th century records the locations of the Lung Meridian and LU3 and LU4 of the upper arm to be in the artery on the medial aspect. This artery corresponds to the brachial artery. The location established by the WHO is on the anterolateral side of the upper arm, where no large arteries exist that can be found by haptic search or angiographically. The anterolateral side of the upper arm belongs to the Yang aspect, which does not coincide with the Yin aspect of Lung Meridian. Conclusions : The WHO's URLM and LU3-4 standards do not agree with the classical literature. The correct route must coincide with the brachial artery passing through the medial side of the humerus. The actual location of LU3-4 is on the medial aspect of the arm, just medial to the border of the biceps brachii muscle, on the brachial artery, 3-4 B-cun inferior to the anterior axillary fold.

Lu-Hf Isotopic Systematics and Its Applications for Geology (Lu-Hf 동위원소시스템의 지질학적 활용)

  • Choi, Sung Hi
    • The Journal of the Petrological Society of Korea
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    • v.23 no.3
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    • pp.229-237
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    • 2014
  • The Lu-Hf isotope system, coupled with the advent of multiple collector inductively coupled plasma source mass spectrometry, is now widely utilized as a tracer for geological processes. The paper presents a comprehensive review on the principles of the Lu-Hf isotopes, and its current and potential applications to both geochronology and petrogenesis. Finally, based on the Lu-Hf isotopic data from Korean mafic and ultramafic rocks, its has been discussed evolution of the mantle beneath the Korean Peninsula.

Synthesis and Luminescence of Lu3(Al,Si)5(O,N)12:Ce3+ Phosphors

  • Ahn, Wonsik;Kim, Young Jin
    • Journal of the Korean Ceramic Society
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    • v.53 no.4
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    • pp.463-467
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    • 2016
  • $Si^{4+}-N^{3-}$ was incorporated into $Ce^{3+}-doped$ lutetium aluminum garnet ($Lu_{2.965}Ce_{0.035}Al_5O_{12}$, $LuAG:Ce^{3+}$) lattices, resulting in the formation of $Lu_{2.965}Ce_{0.035}Al_{5-x}Si_xO_{12-x}N_x$ [(Lu,Ce)AG:xSN]. For x = 0-0.25, the synthesized powders consisted of the LuAG single phase, and the lattice constant decreased owing to the smaller $Si^{4+}$ ions. However, for x > 0.25, a small amount of unknown impurity phases was observed, and the lattice constant increased. Under 450 nm excitation, the PL spectrum of $LuAG:Ce^{3+}$ exhibited the green band, peaking at 505 nm. The incorporation of $Si^{4+}-N^{3-}$ into the $Al^{3+}-O^{2-}$ sites of $LuAG:Ce^{3+}$ led to a red-shift of the emission peak wavelength from 505 to 570 nm with increasing x. Corresponding CIE chromaticity coordinates varied from the green to yellow regions. These behaviors were discussed based on the modification of the $5d^1$ split levels and crystal field surroundings of $Ce^{3+}$, which arose from the Ce-(O,N)8 bonds.

Response of Electrocardiogram of Nile tilapia, Oreochromis niloticus to Light Stimuli (광자극에 대한 역돔의 심전도)

  • Kim, Young-Ki;Yang, Yong-Rhim
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.38 no.3
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    • pp.217-225
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    • 2002
  • The authors examined the response of electrocardiogram(ECG) of Nile tilapia, Oreochromis niloticus [Linnaeus] to light stimuli. The experiments were performed in such a way that three levels of light stimuli(10, 100 and 400 lu$\chi$) were given to fishes with an electrode inserted into their bodies and then their ECGs were recorded continuously for 60 minutes in 16~18$^{\circ}C$. The results which are divided into by day and by night and then analyzed by fishes' conditions are as follows; 1. Nile tilapias reached a stable condition 3 minutes after anesthesia. In stable condition, the heart rate average was 47.6beat/min by day and 45.1beat/min by night. And the action potential average was 1.0.4$mutextrm{V}$ by day and 1.24$mutextrm{V}$ by night. 2. The heart rate average by three levels of light stimuli was, \circled1 In stimulus condition, in case of 10 lu$\chi$ 39.7beat/min by day and 38.2beat/min by night, in case of 100 lu $\chi$8.7beat/min by day and 36.9beat/min by night, and in case of 40.0. lux 36.8 beat/min by day and 35.8beat/min by night. \circled2 In recovery condition, in case of 10 lu$\chi$ 47.1beat/min by day and 46.0beat/min by night, in case of 100 lu$\chi$ 47.2beat/min by day and 45.6 beat/min by night, and in case of 400 lu$\chi$ 48.1beat/min by day and 46.6beat/min by night. 3. The action potential average by three levels of light stimuli was, \circled1 In stimulus condition, in case of 10 lu$\chi$ 1.22$mutextrm{V}$ by day and 0.71$mutextrm{V}$ by night, in case of 100 lu$\chi$ 0..63$mutextrm{V}$ by day and 0.90$mutextrm{V}$ by night, and in case of 400 lu$\chi$ 1.39$mutextrm{V}$ by day and 1.63$mutextrm{V}$ by night \circled2 In recovery condition, in case of 10 lu$\chi$ 1.26$mutextrm{V}$ by day and 1.59$mutextrm{V}$ by night, in case of 100 lu$\chi$ 2.63$mutextrm{V}$ by day and 3.65$mutextrm{V}$ by night, and in case of 400. lu$\chi$ 2.52$mutextrm{V}$ by day and 3.67$mutextrm{V}$ by night.

The Architectural Type of 'Lu' in Choseon Dynasty (조선시대 루건축(樓建築)의 지역별 유형특성)

  • Choi, Mi-Kyung;Lee, Sang-Hae
    • Journal of architectural history
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    • v.19 no.4
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    • pp.7-19
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    • 2010
  • 'Lu' is one of the Korean traditional building structure. The architectural characteristics of the 'Lu' can be classified two types with its use. One is single building type and the other is a part of building type within building complex. This study is about the two-storied 'Lu' that was built on part of building complex. 'Lu' built in building complex such like Sa-chal, Hyang-gyo, Seo-won, Jae-sil, has the similar characters. 1. It is built by taking slope site. 2. Ii is one of four buildings that forms court yard. 3. It uses simple building structure on the purpose of openness 4. It can control view with using window. The column type of 'Lu' can be classified with 3 style. These are $5{\times}2$ Kan style, $3{\times}2$ Kan style and $5{\times}3$ Kan style. It would be assumed with the result of study that $5{\times}2$ Kan style has its origin in Hoe-Rang structure, $3{\times}2$ Kan style is originated from Joong-Moon(middle gate) structure, and $5{\times}3$ Kan is originated from Kang-Dang structure.

Literature Study on the Composition of Samanhyeol (사만혈 구성 경혈에 대한 소고)

  • Seungtae Kim
    • Korean Journal of Acupuncture
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    • v.41 no.2
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    • pp.43-50
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    • 2024
  • Objectives : Samanhyeol is a combination of acupoints located in the cubital and popliteal fossa. It is commonly used in clinical practice to treat acute illnesses such as summerheat stroke, vomiting, diarrhea, and hemorrhagic diseases. There are two types of Samanhyeol in literature: BL40 and LU5, and BL40 and PC3. We investigated which acupoint is representative of Samanhyeol, and more closely fits the definition of Samanhyeol between LU5 and PC3. Methods : We searched for literature related to Samanhyeol, compared the anatomical locations of LU5, PC3, and BL40, examined their indications associated with the effectiveness of Samanhyeol, and checked cases in the literature where LU5 or PC3 was used concurrently with BL40. Results : BL40, one of the Samanhyeol, has been used to treat summerheat stroke, vomiting, diarrhea, and epistaxis in acupuncture texts, and there are many references in the literature to BL40 being used for bloodletting. And BL40 is located in the midpoint of the traverse crease of the popliteal fossa. From this perspective, LU5 may be a more suitable than PC3 because it is located in the midpoint of the cubital crease. However, Samanhyeol is a combination of acupoints used to treat heat stroke, vomiting and diarrhea, and hemorrhagic diseases. Upon analyzing the literature, it was found that LU5 and PC3 have similar efficacy. However, PC3 was used more frequently in cases of severe fever, unconsciousness or syncope. Conclusions : Literature suggests that BL40 is the representative acupoint for Samanhyeol. And PC3 is more appropriate than LU5 for Samanhyeol because its effects are more stronger on heat stroke although both LU5 and PC3 can treat symptoms related to Samanhyeol.

Synthesis of Lu3Al5O12:Ce3+ Nano Phosphor by Coprecipitation Method, and Their Optical Properties (공침법을 이용한 Lu3Al5O12:Ce3+ 나노 형광체 합성과 광학적 특성 분석)

  • Kang, Taewook;Kang, Hyeonwoo;Kim, Jongsu;Kim, Gwangchul
    • Journal of the Semiconductor & Display Technology
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    • v.18 no.4
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    • pp.51-56
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    • 2019
  • LuAG:Ce(Lu3Al5O12:Ce3+) nano phosphor were synthesized by applying the coprecipitation method. It is used to increase the color rendering of phosphor ceramic plate for high power LEDs and laser lighting. Internal quantum efficiency and absorption of LuAG:Ce nano phosphor are 51.5 % and 64.4 %, respectively, which is higher than the previously studied nano phosphors. The maximum absorption wavelength of this phosphor is 450 nm blue light, and the emission wavelength is 510 nm. The emission wavelength shifted to longer wavelength when the concentration of Ce increased in the heat treatment of the reducing atmosphere. Thermal quenching of LuAG nano phosphor was 70 % at 200 ℃, it was explained by their significant quenching of all raman scattering modes, implying the restriction of electron-phonon couplings caused by their defects.

Effects of Invasive Low Level Laser Acupuncture Therapy(LLLAT) at LU7, LR5, LU7+LR5 on the Hyperlipemia Rats Induced by High Fat Diet (열결(列缺), 여구, 열결배여구에 침습적(侵襲的)으로 조사(照射)된 레이저침료법(鍼療法)이 고지혈증(高脂血症) 백서(白鼠)에 미치는 영향(影響))

  • Ihm, Seon-Joo;Youn, Dae-Hwan;Na, Chang-Su
    • Korean Journal of Acupuncture
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    • v.22 no.3
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    • pp.1-15
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    • 2005
  • Objectives: This research was performed to investigate the effect of invasive low level laser acupuncture therapy(LLLAT) at Yolgyol(LU7), Yogu(LR5) and Yolgyol+Yogu(LU7+LR5) on weight gain, food intake, food efficiency, lipid metabolism, atherogenic index, HTR(HDL-cholesterol to total cholesterol ratio) and liver function in hyperlipidemia rats. Methods : Experimental groups were divided into high fat diet group(Control group), high fat diet and LLLAT at LU7(LU7 group), high fat diet and LLLAT at LR5(LR5 group), LLLAT at LU7 and LR5(LU7+LR5 group). Animals was treated by the LLLAT at 30mW-5min once a 2day during 5 weeks. Results: Body weight was decreased significantly in LU7+LR5 group when compared with control group. Food intake was increased significantly in LU7, LR5, LU7+LR5 group when compared with control group. Food efficiency was decreased significantly in LU7, LR5, LU7+LR5 group when compared with control group. In the lipid metabolism, total cholesterol and HDL-cholesterol was decreased significantly in LU7+LR5 group, LDL-cholesterol and phospholipids were decreased significantly in LR5, LU7+LR5 group, triglyceride and fee fatty acid were decreased significantly in LU7 group when compared with control group. Atherogenic index was decreased significantly in LU7, LR5, LU7+LR5 group when compared with control group. HTR was increased significantly in LU7 group when compared with conool group. In the liver function, the significance was not showed in AST and ALT, ALP was decreased significantly in LU7+LR5 group when compared with control group. Conclusions: LLLAT at LU7 and LR5 maybe can manage hyperlipidemia by controlling body weight, food intake, food efficiency ratio and lipid metabolism.

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The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy

  • Zhao, Weichen;He, Chunyuan;Jiang, Junjie;Zhao, Zongbiao;Yuan, Hongzhong;Wang, Facai;Shen, Bingxiang
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.6
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    • pp.427-438
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    • 2022
  • Pyroptosis, a form of cell death associated with inflammation, is known to be involved in diabetic nephropathy (DN), and discoid domain receptor 1 (DDR1), an inflammatory regulatory protein, is reported to be associated with diabetes. However, the mechanism underlying DDR1 regulation and pyroptosis in DN remains unknown. We aimed to investigate the effect of DDR1 on renal tubular epithelial cell pyroptosis and the mechanism underlying DN. In this study, we used high glucose (HG)-treated HK-2 cells and rats with a single intraperitoneal injection of streptozotocin as DN models. Subsequently, the expression of pyroptosis-related proteins (cleaved caspase-1, GSDMD-N, Interleukin-1β [IL-1β], and interleukin-18 [IL-18]), DDR1, phosphorylated NF-κB (p-NF-κB), and NLR family pyrin domain-containing 3 (NLRP3) inflammasomes were determined through Western blotting. IL-1β and IL-18 levels were determined using ELISA. The rate of pyroptosis was assessed by propidium iodide (PI) staining. The results revealed upregulated expression of pyroptosisrelated proteins and increased concentration of IL-1β and IL-18, accompanied by DDR1, p-NF-κB, and NLRP3 upregulation in DN rat kidney tissues and HG-treated HK-2 cells. Moreover, DDR1 knockdown in the background of HG treatment resulted in inhibited expression of pyroptosis-related proteins and attenuation of IL-1β and IL-18 production and PI-positive cell frequency via the NF-κB/NLRP3 pathway in HK-2 cells. However, NLRP3 overexpression reversed the effect of DDR1 knockdown on pyroptosis. In conclusion, we demonstrated that DDR1 may be associated with pyroptosis, and DDR1 knockdown inhibited HG-induced renal tubular epithelial cell pyroptosis. The NF-κB/NLRP3 pathway is probably involved in the underlying mechanism of these findings.

Phase Stability of bulk $(R_{0.8}Ca_{0.2})Ba_2Cu_3O_z$ (R = Lu and Y) Compounds ($(R_{0.8}Ca_{0.2})Ba_2Cu_3O_{7-z}$ (R = Lu 및 Y)의 상 안정도 특성)

  • Bae, S.M.;Lee, H.K.
    • Progress in Superconductivity
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    • v.11 no.1
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    • pp.25-29
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    • 2009
  • Polycrystalline samples of $(R_{0.8}Ca_{0.2})Ba_2Cu_3O_{7-z}$ (R = Lu and Y) were synthesized by a solid-state reaction route, and the phase stabilities were examined by heating at temperatures between $800^{\circ}C$ and $900^{\circ}C$ in various atmospheres. A comparative analyses of the x-ray diffraction data of the $(Lu_{0.8}Ca_{0.2})Ba_2Cu_3O_{7-z}$ and $(Y_{0.8}Ca_{0.2})Ba_2Cu_3O_{7-z}$ compounds showed that the 123 phase of both compounds is stable under heating in air and $O_2$ of 1 atm. However, contrary to the $(Y_{0.8}Ca_{0.2})Ba_2Cu_3O_{7-z}$ compound, the $(Lu_{0.8}Ca_{0.2})Ba_2Cu_3O_z$ compound was found to become unstable when heated in the low oxygen partial pressure below about 8 % $O_2\;in\;N_2$, Considering the instability of parent $LuBa_2Cu_3O_z$ compound, this result suggests that the phase stability of Lu-based 123 compounds is sensitive to both the composition and the oxygen partial pressure.

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