• The Journal of Korean Medicine
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• v.37 no.3
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• pp.27-38
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• 2016

Objectives: According to Korean Medicine theory, the skin color of LU10 serves as a diagnostic clue to dyspeptic symptoms. The aims of this study were (1) to find the difference of skin color in LU10 region between functional dyspepsia (FD) and healthy control (HC) and (2) to examine the relationship between LU10 skin color parameters and dyspeptic symptoms. Methods: 39 participants (29 FD and 10 HC) have participated in this study. They were asked to complete gastrointestinal scale (GIS), gastrointestinal symptom rating scale (GSRS), Nepean dyspepsia index (NDI), functional dyspepsia-related quality of life (FD-QoL), visual analogue scale (VAS) for dyspeptic symptoms, food retention questionnaire (FRQ) and cold heat questionnaire (CHQ). $L^*$ (luminance), $a^*$ (red-green balance) and $b^*$ (yellow-blue balance) values of LU10 region were calculated through digital images of the participant's hand. Then we evaluated test-retest reliability of $L^*$, $a^*$ and $b^*$ values of LU10 region. Additionally, we compared $L^*$, $a^*$ and $b^*$ values of LU10 between FD and HC, and examined the relationship between LU10 color parameters and seven questionnaires scores. Results: Only $L^*$ values in LU10 region were significantly higher in FD compared with HC. GIS scores and the subset scores of NDI had a positive correlation with $L^*$ values significantly. Correlation coefficients of test-retest reliability of skin color measurement of LU10 ranged from 0.871 to 0.936 representing very strongly statistically significant (P<0.001). Conclusions: We confirmed the difference of skin color in LU10 region between FD and HC, and relationship between LU10 skin color parameters and dyspeptic symptoms.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.1 no.1
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• pp.53-61
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• 2015

Lutetium-177 ($T_{1/2}=6.71day$) is an adequate radionuclide for therapy, which has both beta emission ($E_{max}=497keV$) for therapeutic effect and gamma emission (113 and 208 keV) for imaging. $^{177}Lu$ labeled ethylenediamine-N,N,N',N'-tetrakis (methylene phosphonic acid) (EDTMP) and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraaminomethylenephosphonate (DOTMP) have been proposed as radiopharmaceuticals for bone pain palliation. In this study, we compared radiochemistry and biodistribution of $^{177}Lu$-EDTMP and $^{177}Lu$-DOTMP. EDTMP and DOTMP were synthesized, and 1 mg of each was labeled with $^{177}Lu$ at pH 7~8 with high efficiency (>98%). For comparative biodistribution studies, $^{177}Lu$-EDTMP or $^{177}Lu$-DOTMP were injected into ICR-mice through tail vein, and then biodistribution data were obtained as percentages of injected dose per gram of tissue (% ID/g). Urine excretions of both agents in mice were checked for 7 days. Rat images were also obtained after injection of $^{177}Lu$-EDTMP or $^{177}Lu$-DOTMP. $^{177}Lu$-DOTMP (100% at 1 min) showed faster labeling than $^{177}Lu$-EDTMP (100% at 30 min). Both of them were stable at least for 21 days at room temperature. High bone uptakes were found for both $^{177}Lu$-EDTMP and $^{177}Lu$-DOTMP: 38.0 and 34.1% ID/g at 3 hr, respectively; and 33.2 and 18.8% ID/g at 7 day, respectively. Rapid excretions to urine were found for both agents ($^{177}Lu$-EDTMP: 56%, $^{177}Lu$-DOTMP: 63% at 1 day). Other organs showed very low uptakes. Rat images of both $^{177}Lu$-EDTMP and $^{177}Lu$-DOTMP showed high bone uptakes and low soft tissue uptakes. In conclusion, both $^{177}Lu$-EDTMP and $^{177}Lu$-DOTMP showed high potential as bone pain palliation agents. $^{177}Lu$-EDTMP showed higher bone uptake and slower bone clearance in mice than those of $^{177}Lu$-DOTMP.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.38 no.3
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• pp.217-225
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• 2002

The authors examined the response of electrocardiogram(ECG) of Nile tilapia, Oreochromis niloticus [Linnaeus] to light stimuli. The experiments were performed in such a way that three levels of light stimuli(10, 100 and 400 lu$\chi$) were given to fishes with an electrode inserted into their bodies and then their ECGs were recorded continuously for 60 minutes in 16~18$^{\circ}C$. The results which are divided into by day and by night and then analyzed by fishes' conditions are as follows; 1. Nile tilapias reached a stable condition 3 minutes after anesthesia. In stable condition, the heart rate average was 47.6beat/min by day and 45.1beat/min by night. And the action potential average was 1.0.4$mutextrm{V}$ by day and 1.24$mutextrm{V}$ by night. 2. The heart rate average by three levels of light stimuli was, \circled1 In stimulus condition, in case of 10 lu$\chi$ 39.7beat/min by day and 38.2beat/min by night, in case of 100 lu $\chi$8.7beat/min by day and 36.9beat/min by night, and in case of 40.0. lux 36.8 beat/min by day and 35.8beat/min by night. \circled2 In recovery condition, in case of 10 lu$\chi$ 47.1beat/min by day and 46.0beat/min by night, in case of 100 lu$\chi$ 47.2beat/min by day and 45.6 beat/min by night, and in case of 400 lu$\chi$ 48.1beat/min by day and 46.6beat/min by night. 3. The action potential average by three levels of light stimuli was, \circled1 In stimulus condition, in case of 10 lu$\chi$ 1.22$mutextrm{V}$ by day and 0.71$mutextrm{V}$ by night, in case of 100 lu$\chi$ 0..63$mutextrm{V}$ by day and 0.90$mutextrm{V}$ by night, and in case of 400 lu$\chi$ 1.39$mutextrm{V}$ by day and 1.63$mutextrm{V}$ by night \circled2 In recovery condition, in case of 10 lu$\chi$ 1.26$mutextrm{V}$ by day and 1.59$mutextrm{V}$ by night, in case of 100 lu$\chi$ 2.63$mutextrm{V}$ by day and 3.65$mutextrm{V}$ by night, and in case of 400. lu$\chi$ 2.52$mutextrm{V}$ by day and 3.67$mutextrm{V}$ by night.

• The Journal of the Petrological Society of Korea
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• v.23 no.3
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• pp.229-237
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• 2014

The Lu-Hf isotope system, coupled with the advent of multiple collector inductively coupled plasma source mass spectrometry, is now widely utilized as a tracer for geological processes. The paper presents a comprehensive review on the principles of the Lu-Hf isotopes, and its current and potential applications to both geochronology and petrogenesis. Finally, based on the Lu-Hf isotopic data from Korean mafic and ultramafic rocks, its has been discussed evolution of the mantle beneath the Korean Peninsula.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.10
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• pp.303-308
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• 2020

The ReLU(Rectified Linear Unit) function has been dominantly used as a standard activation function in most deep artificial neural network models since it was proposed. Later, Leaky ReLU, Swish, and Mish activation functions were presented to replace ReLU, which showed improved performance over existing ReLU function in image classification task. Therefore, we recognized the need to experiment with whether performance improvements could be achieved by replacing the RELU with other activation functions in the super resolution task. In this paper, the performance was compared by changing the activation functions in EDSR model, which showed stable performance in the super resolution task. As a result, in experiments conducted with changing the activation function of EDSR, when the resolution was converted to double, the existing activation function, ReLU, showed similar or higher performance than the other activation functions used in the experiment. When the resolution was converted to four times, Leaky ReLU and Swish function showed slightly improved performance over ReLU. PSNR and SSIM, which can quantitatively evaluate the quality of images, were able to identify average performance improvements of 0.06%, 0.05% when using Leaky ReLU, and average performance improvements of 0.06% and 0.03% when using Swish. When the resolution is converted to eight times, the Mish function shows a slight average performance improvement over the ReLU. Using Mish, PSNR and SSIM were able to identify an average of 0.06% and 0.02% performance improvement over the RELU. In conclusion, Leaky ReLU and Swish showed improved performance compared to ReLU for super resolution that converts resolution four times and Mish showed improved performance compared to ReLU for super resolution that converts resolution eight times. In future study, we should conduct comparative experiments to replace activation functions with Leaky ReLU, Swish and Mish to improve performance in other super resolution models.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.8
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• pp.1-11
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• 2004

A comprehensive study has been made for the investigation of the convergence and stability characteristics of the LU scheme for solving the Navier-Stokes equations on unstructured meshes. For this purpose the characteristics of the LU scheme was initially studied for a scalar model equation. Then the analysis was extended to the Navier-Stokes equations. It was shown that the LU scheme has an inherent stiffness in the streamwise direction. This stiffness increases when the grid aspect ratio becomes high and the cell Reynolds number becomes small. It was also shown that the stiffness related to the grid aspect ratio can be effectively eliminated by performing proper subiteration. The results were validated for a flat-plate turbulent flow.

• Journal of Internet Computing and Services
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• v.14 no.6
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• pp.41-47
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• 2013

GP-GPUs are general purposed GPUs for numerical computation based on multiple threads which are originally for graphic processing. GP-GPUs provide cache memory in a form of shared memory which user programs can access directly, unlikely typical cache memory. In this research, we implemented the parallel block LU decomposition program to utilize cache memory in GP-GPUs. The parallel blocked LU decomposition program designed with Nvidia CUDA C run 7~8 times faster than nun-blocked LU decomposition program in the same GP-GPU computation environment.

• Korean Journal of Acupuncture
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• v.20 no.2
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• pp.1-20
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• 2003

This study was examined for characteristics of acupuncture of LU10 on the abdominal thermography of health subject. The volunteers who participating in this study had taken rest for 20 - 30 mins in room temperature $(23-25^{\circ}C)$ before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day. The thermography of abdomen including a below part of the chest was taken using Infra-Red Imaging System (IR 2000, MEDI-CORE Co., Korea) by time interval of 15 minutes at 15 min before, just before and 15 min after, 30 min after and 45 min after acupuncture stimulation. Acupuncture was applied to both LU10 for 30 mins. The results showed that acupuncture of LU10 for 30 mins had more potencies of changes on all the ROIs of abdominal thermography than those of control group. Also, those responses were significantly clear at the A1, A3, A6, A7 and A9 areas. It was observed that the quantities of thermal changes following acupuncture of LU10 been increased significantly comparing that of control group at the all ROIs (region of interest). These effects have more potencies at the upper (A1 and A2) and below (A7, A8, A9) abdominal areas than midline ones (A4, A5, and A6). These results suggest that acupuncture of LU10 having the characteristics of controls of chill and fever (寒熱) may modulate thermal distributions and changes of abdominal areas including the below of chest.

• Proceedings of the Korea Information Processing Society Conference
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• 2020.05a
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• pp.504-507
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• 2020

ReLU(Rectified Linear Unit) 함수는 제안된 이후로 대부분의 깊은 인공신경망 모델들에서 표준 활성함수로써 지배적으로 사용되었다. 이후에 ReLU 를 대체하기 위해 Leaky ReLU, Swish, Mish 활성함수가 제시되었는데, 이들은 영상 분류 과업에서 기존 ReLU 함수 보다 향상된 성능을 보였다. 따라서 초해상화(Super Resolution) 과업에서도 ReLU 를 다른 활성함수들로 대체하여 성능 향상을 얻을 수 있는지 실험해볼 필요성을 느꼈다. 본 연구에서는 초해상화 과업에서 안정적인 성능을 보이는 EDSR(Enhanced Deep Super-Resolution Network) 모델의 활성함수들을 변경하면서 성능을 비교하였다. 결과적으로 EDSR 의 활성함수를 변경하면서 진행한 실험에서 해상도를 2 배로 변환하는 경우, 기존 활성함수인 ReLU 가 실험에 사용된 다른 활성함수들 보다 비슷하거나 높은 성능을 보였다. 하지만 해상도를 4 배로 변환하는 경우에서는 Leaky ReLU 와 Swish 함수가 기존 ReLU 함수대비 다소 향상된 성능을 보임을 확인하였다. 구체적으로 Leaky ReLU 를 사용했을 때 기존 ReLU 보다 영상의 품질을 정량적으로 평가할 수 있는 PSNR 과 SSIM 평가지표가 평균 0.06%, 0.05%, Swish 를 사용했을 때는 평균 0.06%, 0.03%의 성능 향상을 확인할 수 있었다. 4 배의 해상도를 높이는 초해상화의 경우, Leaky ReLU 와 Swish 가 ReLU 대비 향상된 성능을 보였기 때문에 향후 연구에서는 다른 초해상화 모델에서도 성능 향상을 위해 활성함수를 Leaky ReLU 나 Swish 로 대체하는 비교실험을 수행하는 것도 필요하다고 판단된다.

• Korean Journal of Acupuncture
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• v.24 no.1
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• pp.113-129
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• 2007

Objectives : This research was performed to investigate the effect of acupuncture using invasive low level laser therapy (LLLT) at Yolgyol (LU7) + Yogu (LR5) on weight gain, food intake, food efficiency, lipid metabolism, atherogenic index, HTR (HDL-cholesterol to total cholesterol ratio) and morphological change of hepatic tissue in hyperlipdemia rats. Methods : Experimental groups were divided into high fat diet group (Control group), high fat diet and acupuncture therapy group at LU7 + LR5 (AT group), high fat diet and acupuncture group using 10 mW LLLT at LU7 +LR5 (LA10 group), high fat diet and acupuncture group using 20 mW LLLT at LU7+LR5(LA20 group), high fat diet and acupuncture group using 60 mW LLLT at LU7 + LR5 (LA60 group), once per 3 days during 9 weeks. Results : Body weight was decreased significantly in AT and LA20 groups compared with Control group. Food intake was increased significantly in LA60 group compared with Control group. Food efficiency was decreased significantly in LA10, LA20 and LA60 groups compared with control group. In the lipid metabolism, total cholesterol was decreased significantly in AT, LA10, LA20 and LA60 groups, triglyceride was decreased significantly in LA10, LA20 and LA60 groups, TG/HDL-cholesterol ratio was decreased significantly in LA 60 group compared with control group. In the morphological change, hepatic tissue were not showed balloning degeneration and irregular arrangement of hepatic cell in LA10 and LA20 groups with control group. Conclusions : Acupuncture using LLLT at LU7+LR5 can manage hyperlipemia by controlling body weight, food intake, food efficiency ratio and lipid metabolism.