• 한국사회정책
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• 제25권1호
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• pp.287-320
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• 2018

이 연구는 노인장기요양서비스 분야에서 복지기술 준시장(quasi-market)의 성격과 문제점을 파악하고 향후 복지기술 발전에의 함의를 도출하고자 하였다. 개발자들에 대한 질적 인터뷰를 분석한 결과, 우리나라의 노인장기요양보험제도가 가지는 제도적 특성은 그 자체로 복지기술 시장을 제약하고 있음을 확인하였다. 즉 노인장기요양보험제도는 복지용구에 대한 제도적 지원을 통해 중증 장기요양보험대상자에 대한 제한된 유효수요 창출과 낮은 복지기술 수준의 복지용구 시장형성에 도움이 되었으나, 노인장기요양보험이 취하고 있는 정책 패러다임은 오히려 복지기술 시장의 확대와 질적 성장을 제약하는 왜곡된 관계의 양면성을 보이고 있다. 구체적으로 보면, 중증요양대상자 중심의 일방적 돌봄과 의존, 제도 내외 서비스 제공자간의 단절적 보호, 낮은 수가, 지원품목 지정 등의 엄격한 규제, 급여방식 등의 노인장기요양보험의 특징으로 인해, 복지용구 시장은 급여지원이 되는 범위 내에서 협소하게 형성되어 그 틀을 벗어나지 못하고 있다. 또한 노인들의 자립을 유도하는 복지기술보다는 중증 노인들의 수발에 필요한 최소한의 획일적인 복지용구가 주로 개발되고 있었다. 정부지원이 낮은 수준이면서도 엄격한 규제로 인해 질적 경쟁이 발생할 수 없는 구조인 것이다. 본 연구는 결론에서 이러한 연구결과를 토대로 복지기술 시장에 대한 발전 전망과 정책적 방향을 제시하고자 하였다.

• 한국산학기술학회논문지
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• 제22권6호
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• pp.75-82
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• 2021

디젤엔진의 열효율을 높이면서 NOx와 PM을 효과적으로 저감시키기 위해 HCCI(Homogeneous Charge Compression Ignition), PCCI(Premixed Charge Compression Ignition), RCCI(Reactivity Controlled Compression Ignition) 등의 저온연소(LTC: Low Temperature Combustion)전략이 개발되어 왔다. 본 연구에서는 저반응성 연료로는 가솔린을 사용하고 고반응성 연료로는 디젤을 사용하는 RCCI 엔진에서 고반응성 연료인 디젤연료의 분사 시기와 이단 분사비율이 성능 및 배출가스에 미치는 영향을 수치해석을 통하여 파악하고자 하였다. 이단 분사 시 첫 번째 분사시기가 너무 진각되면 연소가 느려지면서 연소온도가 낮아져 연소성능이 저하되고 HC, CO가 증가한다. 대략 -60°ATDC 의 분사시기가 연소성능, 배출가스 및 최대압력상승률을 고려하였을 때 가장 최적의 분사시기라고 판단된다. 이단 분사 시 두 번째 분사시기를 변경하였을 때 연소성능 및 배출가스, 최대압력상승률 등을 고려하면 대략 -30°ATDC 부근에서 최적인 것으로 판단된다. 이단 분사 시 분사량 비율은 첫 번째 분사량을 60% 정도로 하였을 때 최적의 결과를 얻었다. 마지막으로 단일 분사보다는 이단 분사한 경우 연소성능 및 배출가스 부분에서 더 효과적인 것으로 판단된다.

• 대한한방부인과학회지
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• 제34권3호
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• pp.29-48
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• 2021

Objectives: Banchong-san (BCS) is a herbal formula composed of 13 korean medicinal herbs and is traditionally used to treat inflammatory diseases and pain. The object of this study was to research the antioxidant, anti-inflammatory, antipruritic and antimicrobial effects of the BCS in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Methods: In this experiment, effects of BCS on the following four were measured as follows: (1) Anti-oxidative effects were evaluated by 1,1-diphenyl-2-picryl-hydrazyl (DPPH) Radical scavenging activity, 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) Radical scavenging activity. (2) Anti-inflammatory effects were evaluated by the production amount of Reactive oxygen species (ROS), Nitric oxide (NO), Interleukin-1β (IL-1β), Interleukin 6 (IL-6), tumor necrosis factor-α (TNF-α), Prostaglandin E2 (PGE₂), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2)(the previous two are "mRNA"), extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), p38 mitogen-activated protein kinases (p38), inhibitor of nuclear factor kappa B (IκBα), nuclear factor kappa B (NF-κB) (the previous five are "Protein") in LPS-Stimulated RAW 264.7 cells. (3)Antipruritic effects were evaluated by the production amount of histamine, Leukotriene B4 (LTB4), LeukotrieneC4 (LTC4) Levels in phorbol 12-myristate 13-acetate(PMA)/ionomycin-stimulated MC/9 mast cell. (4) Anti-microbial effects were evaluated by the growth suppression of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Aspergillus niger. Results: The following results were obtained through each measurement: (1) DPPH Radical Scavenging Activity, ABTS Radical Scavenging Activity evoked a significant concentration-dependent increase. (2) ROS, NO, IL-1β, IL-6, TNF-α, PGE₂ production amount, iNOS, COX-2 mRNA expression were significantly reduced in the BCS extraction group compared with the control group and significantly decreased the amount of ERK, JNK, p38, NF-κB Protein expression. The amount of IκB-α Protein Expression have increased significantly. (3) The amounts of histamine, LTB4, LTC4 were significantly decreased. (4) The antibacterial efficacy, BCS inhibited the growth of Escherichia coli, Pseudomonas aeruginosa at concentrations of 5 ㎍/ml, but did not suppress the growth of staphylococcus aureus and aspergillus niger. Conclusions: The experimental results show that BCS has anti-oxidant, anti-inflammatory, antipruritic and antimicrobial properties.

• 제어로봇시스템학회논문지
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• 제21권4호
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• pp.301-308
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• 2015

In this paper, we propose an LTBC (Low Tension and Load Balance Control) scheme to improve a coiling shape control by reduction the tension fluctuation by the torque disturbance in the down coiler process of hot strip mills. The proposed controller is a combination of an LTC to control the overload at load-on in the mandrel and an LBC to regulate the load balance of the upper and bottom pinch roll. A tension calculation model is suggested with the concept of the tension deviation. The effectiveness of the proposed control scheme is verified from simulation under a disturbance of the pinch roll torque. Using a field test, we show that the performance of the shape and tension control is improved by the LTBC control.

• The Korean Journal of Physiology and Pharmacology
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• 제2권6호
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• pp.779-786
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• 1998

A reversed-phase high-performance liquid chromatogrphy (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram level. This procedure makes it possible to extract complex mixtures of eicosanoids efficiently with a single step and to analyze them simultaneously by RP-HPLC from biological samples using octadesylsilyl silica extraction column and $PGB_2$ as an internal standard. The cyclooxygenase products {prostaglandin $(PG)D_2,\;PGE_1,\;PGE_2,\;PGF_{1{\alpha}},\;PGF{2{\alpha}},\;6-keto-PGF_{1{\alpha}},$ and thromboxane $B_2(TXB_2)}$ and lipid peroxidation product, isoprostanes, of arachidonic acid were monitored by one isocratic HPLC system at 195 nm wavelength. The lipoxygenase products ${leukotriene(LT)B_4,\;LTC_4,\;LTD_4,$ and 5-hydroxyeicosatetraenoic acid (5-HETE), 12-HETE, 15-HETE} were measured by another isocratic HPLC system at 280 nm for LTs and 235 nm for HETEs. This method provides a simple and reliable way to extract and assess quantitatively the final arachidonic acid metabolites.

• 지역사회간호학회지
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• 제31권1호
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• pp.34-42
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• 2020

Purpose: The objective of this study was to identify whether spirituality mediates the relationship between empathy and elderly care performance among Long Term Care (LTC) hospitals nurses in Korea. Methods: The data collection was performed July 1st to August 31th, 2018. Participants were 119 nurses from three long-term care hospitals in Korea. Self-reported questionnaires were administered to assess general characteristics, empathy, spirituality and elderly care performance. The data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation coefficients, and three-stage simple and multiple regression analysis as proposed by Baron and Kenny. Results: The level of elderly care performance of participants was significantly different based on age (F=3.92, p=.010) and nurse's position (t=-2.18, p=.031). Spirituality had a significant mediating effect on the relationship between empathy and elderly care performance (Z=3.64, p<.001). Conclusion: As spirituality completely mediates the relationship between empathy and elderly care performance, it is necessary to develop a nursing education program that applies spirituality and empathy and supports religious activities at an institutional level.

• 한국자동차공학회논문집
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• 제20권3호
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• pp.141-147
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• 2012

A direct injection diesel engine with large amount of exhaust gas recirculation was used to investigate low temperature diesel combustion. Pilot injection strategy was adopted in low temperature diesel combustion to reduce high carbon monoxide and hydrocarbon emissions. Combustion characteristics and exhaust emissions of low temperature diesel combustion under different pilot injection timings, pilot injection quantities and injection pressures were analyzed. Retarding pilot injection timing, increasing pilot injection quantity and higher injection pressure advanced main combustion timing and increased peak heat release rate of main combustion. As a result of these strategies, carbon monoxide and hydrocarbon emissions were reduced. Soot emission was slightly increased with retarded pilot injection timing while the effect of pilot injection on nitrogen oxides emission was negligible under low combustion temperature condition. Spatial distribution of fuel from the spray targeting visualization was also investigated to provide more insight into the reason for the reduction in carbon monoxide and hydrocarbon emissions.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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• pp.232-232
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• 1994

인삼이 면역계 질환의 일종인 과민성 반응에 대한 치료약으로서의 가능성을 연구하기 위해서 in viva와 in vitra실험을 수행하였다. in vitra실험으로서는 hyaluronidase의 활성을 지표로 삼았으며, in viva실험에서는 mouse이각, rat등피부, 복강 비만세포, 그리고 guinea pig의 ileum에서 면역반응에 대한 아답타겐의 작용을 관찰하였다. in uitra 실험에서는 hyaluronidase와 histamine 분비를 항알레르기 작용의 지표로 사용하였다. hyaluronidase의 경우 그 활성은 Cacl2로 활성화 시키기 전이나 후에 모두 아답타겐(100, 50, 및 10 mg/ml)에 의해서 현저하게 억제되었다. 한편 rat 복강 비만 세포에서의 histamine유리 시험에서는 아답타겐(0.5, 1, 5mg/ml)이 histamine유리가 증가되었다. Guinea pig의 ileum 평활근에서는 아답타겐이 평활근 자극 작용없이 항히스타민 효과률 나타내었다. in uiua 실험의 첫 단계로 우리는 혈관 투과성에 미치는 아답타겐의 효과를 mouse 이각과 rat 등피부에서 관찰하였다. Mouse이각에서의 실험에서는 hoistamine, serotonin, 그리고 LTC4로 challenge하여 관찰한 결과 histamine과 serotonin의 경우, 혈관투과성 항진은 아답타겐(50-400mg/m1)에 의해서 유의성있게 억제되었으나, rat 등 피부에서는 mouse에서와는 달리 48-hr PCA가 증가 되었고, histamine에 의한 혈관투과성 항진은 아답타겐에 의해 영향을 받지 않았다. 반면에 compound 48/80과 serotonin에 의한 혈관투과성 항진은 mouse 의 경우에서처럼 아답타겐에 의해 억제되었다.

• Journal of Electrical Engineering and Technology
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• 제4권4호
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• pp.429-437
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• 2009

This paper proposes a hybrid voltage controller based on a hierarchical control structure for implementation in the Jeju power system. The hybrid voltage controller utilizes the coordination of various reactive power devices such as generators, switched shunt devices and LTC to regulate the pilot voltage of an area or zone. The reactive power source can be classified into two groups based on action characteristics, namely continuous and discrete. The controller, which regulates the pilot bus voltage, reflects these characteristics in the coordination of the two types of reactive power source. However, the continuous type source like generators is a more important source than the discrete type for an emergency state such as a voltage collapse, thereby requiring a more reactive power reserve of the continuous type to be utilized in the coordination in order to regulate the pilot bus voltage. Results show that the hybrid controller, when compared to conventional methods, has a considerable improvement in performance when adopted to control the pilot bus voltage of the Jeju island system.

• 한국연소학회지
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• 제18권4호
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• pp.12-20
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• 2013

The ignition delay time is an important factor to understand the combustion characteristics of internal combustion engine. In this study, ignition delay times of cool and thermal flame were observed separately in homogeneous charge compression ignition(HCCI) engine. This study presents numerical investigation of ignition delay time of n-heptane and alcohol(ethanol and n-butanol) binary fuel. The $O_2$ concentration in the mixture was set 9-10% to simulate high exhaust gas recirculation(EGR) rate condition. The numerical study on the ignition delay time was performed using CHEMKIN codes with various blending ratios and EGR rates. The results revealed that the ignition delay time increased with increasing the alcohol fraction in the mixture due to a decrease of oxidation of n-heptane at the low temperature. From the numerical analysis, ethanol needed more radical and higher temperature than n-butanol for oxidation. In addition, thermal ignition delay time is sharply increasing with decreasing $O_2$ fraction, but cool flame ignition delay time changes negligibly for both binary fuels. Also, in high temperature regime, the ignition delay time showed similar tendency with both blends regardless of blending ratio and EGR rate.