• Journal of Ginseng Research
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• v.45 no.5
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• pp.546-554
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• 2021

Background: Diabetes mellitus and hypertension often occur together, amplifying cardiovascular disease (CVD) risk and emphasizing the need for a multitargeted treatment approach. American ginseng (AG) and Korean Red Ginseng (KRG) species could improve glycemic control via complementary mechanisms. Additionally, a KRG-inherent component, ginsenoside Rg3, may moderate blood pressure (BP). Our objective was to investigate the therapeutic potential of coadministration of Rg3-enriched Korean Red Ginseng (Rg3-KRG) and AG, added to standard of care therapy, in the management of hypertension and cardiometabolic risk factors in type-2 diabetes. Methods: Within a randomized controlled, parallel design of 80 participants with type-2 diabetes (HbA1c: 6.5-8%) and hypertension (systolic BP: 140-160 mmHg or treated), supplementation with either 2.25 g/day of combined Rg3-KRG + AG or wheat-bran control was assessed over a 12-wk intervention period. The primary endpoint was ambulatory 24-h systolic BP. Additional endpoints included further hemodynamic assessment, glycemic control, plasma lipids and safety monitoring. Results: Combined ginseng intervention generated a mean ± SE decrease in primary endpoint of 24-h systolic BP (-3.98 ± 2.0 mmHg, p = 0.04). Additionally, there was a greater reduction in HbA1c (-0.35 ± 0.1% [-3.8 ± 1.1 mmol/mol], p = 0.02), and change in blood lipids: total cholesterol (-0.50 ± 0.2 mmol/l, p = 0.01), non-HDL-C (-0.54 ± 0.2 mmol/l, p = 0.01), triglycerides (-0.40 ± 0.2 mmol/l, p = 0.02) and LDL-C (-0.35 ± 0.2 mmol/l, p = 0.06) at 12 wks, relative to control. No adverse safety outcomes were observed. Conclusion: Coadministration of Rg3-KRG + AG is an effective addon for improving BP along with attaining favorable cardiometabolic outcomes in individuals with type 2 diabetes. Ginseng derivatives may offer clinical utility when included in the polypharmacy and lifestyle treatment of diabetes. Clinical trial registration: Clinicaltrials.gov identifier, NCT01578837;

• Korean Journal of Remote Sensing
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• v.37 no.5_3
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• pp.1425-1434
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• 2021

Continuous and periodic data acquisition must be preceded to maintain and manage the river facilities effectively. Adapting the existing general facilities methods, which include river surveying methods such as terrestrial laser scanners, total stations, and Global Navigation Satellite System (GNSS), has limitation in terms of its costs, manpower, and times to acquire spatial information since the river facilities are distributed across the wide and long area. On the other hand, the Mobile Mapping System (MMS) has comparative advantage in acquiring the data of river facilities since it constructs three-dimensional spatial information while moving. By using the MMS, 184,646,009 points could be attained for Anyang stream with a length of 4 kilometers only in 20 minutes. Levee points were divided at intervals of 10 meters so that about 378 levee cross sections were generated. In addition, the waterside maximum and average slope could be automatically calculated by separating slope plane form levee point cloud, and the accuracy of RMSE was confirmed by comparing with manually calculated slope. The reference slope was calculated manually by plotting point cloud of levee slope plane and selecting two points that use location information when calculating the slope. Also, as a result of comparing the water side slope with slope standard in basic river plan for Anyang stream, it is confirmed that inspecting the river facilities with the MMS point cloud is highly recommended than the existing river survey.

• Journal of The Korean Society of Grassland and Forage Science
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• v.41 no.3
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• pp.147-154
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• 2021

Cutting management has been identified as a critical factor in the alfalfa production systems because it has a significant impact on maximizing yield and maintaining the forage quality. The objective of this experiment was to determine the proper cutting height according to harvesting time for optimizing nutrient yield and forage nutritive quality of alfalfa grown in alpine regions of Korea. Alfalfa was sown at a seeding rate of 30 kg/ha in August 2018 and harvested at four cuttings in 2019 (3 May, 2 July, 11 September, and 13 October). Cutting heights were adjusted at 5, 15, and 25 cm above the soil surface. Alfalfa plant was tallest at the third cutting (109 cm), which was on average 35 cm taller than the first or second cutting. Relative feed value (RFV) remained unaffected by cutting height at the first harvest, but increased consistently in subsequent harvests as cutting height increased. Alfalfa collected at the first and fourth cuttings had the highest RFV (mean 152), which was on average 8 and 67 units higher than the second and third harvests, respectively. At each harvest, in vitro dry matter digestibility was highest in alfalfa cut at a 25-cm height. Dry matter (DM) production at each cutting height was highest in the first cutting, accounting for on average 36-37% of total annual DM production, and lowest in the fourth harvest, accounting for about 11-13% of the total DM yield. The total dry matter production (in four harvests) was 4,218 kg/ha higher when alfalfa was subjected to a cutting height of 5 cm rather than 25 cm. Cutting height had no effect on total crude protein yield, but from the first to fourth cutting, the protein yield followed a decreasing trend. Finally, there were visible declines in forage nutritive quality when alfalfa was cut at a shorter height. However, the magnitude of difference in total forage yield may outweigh the slight decline in forage quality when alfalfa is cut at a lower height. The findings of this study could help the alfalfa growers make better harvest management decisions.

• Journal of Microbiology and Biotechnology
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• v.29 no.7
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• pp.1043-1052
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• 2019

Active lipase-producing bacterium Burkholderia gladioli Bps-1 was rapidly isolated using a modified trypan blue and tetracycline, ampicillin plate. The electro-phoretically pure enzyme was obtained by purification using ethanol precipitation, ion-exchange chromatography, and gel filtration chromatography. The molecular weight was 34.6 kDa and the specific activity was determined to be 443.9 U/mg. The purified lipase showed the highest activity after hydrolysis with $p-NPC_{16}$ at a pH of 8.5 and $50^{\circ}C$, and the $K_m$, $k_{cat}$, and $k_{cat}/K_m$ values were 1.05 mM, $292.95s^{-1}$ and $279s^{-1}mM^{-1}$, respectively. The lipase was highly stable at $7.5{\leq}pH{\leq}10.0$. $K^+$ and $Na^+$ exerted activation effects on the lipase which had favorable tolerance to short-chain alcohols with its residual enzyme activity being 110% after being maintained in 30% ethanol for 1 h. The results demonstrated that the lipase produced by the strain B. gladioli Bps-1 has high enzyme activity and is an alkaline lipase. The lipase has promising chemical properties for a range of applications in the food-processing and detergent industries, and has particularly high potential for use in the manufacture of biodiesel.

• Korean Journal of Environment and Ecology
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• v.32 no.6
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• pp.676-685
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• 2018

This study is to compare carbon budget between serpentine sites and non-serpentine sites dominated by Pinus densiflora forest in the Andong serpentine area where has high values of magnesium and low values of calcium, and are usually deficient in nitrogen and phosphorus, but rich in heavy metals such as nickel, chrome, cobalt, etc. and to measure soil $CO_2$ efflux and environmental factors between January 2017 and December 2017. Soil $CO_2$ efflux was measured with LI-6400 once a month; the soil temperature at 10 cm depth, air temperature, soil moisture contents, and solar radiation were measured in continuum. Soil $CO_2$ efflux in the serpentine area and non-serpentine were $151.71{\pm}75.09g\;CO_2{\cdot}m^{-2}month^{-1}$(42.48 ~ 262.61 g $CO_2{\cdot}m^{-2}month^{-1}$) and $165.09{\pm}118.96g\;CO_2{\cdot}m^{-2}month^{-1}$(20.94 ~ 449.24 g $CO_2{\cdot}m^{-2}month^{-1}$), respectively. Carbon storage in the serpentine area and non-serpentine area were 91.90, $222.85ton{\cdot}ha^{-1}$, respectively. Carbon absorption in the serpentine area and non-serpentine area were 7.99, $17.41ton{\cdot}ha^{-1}yr^{-1}$, respectively. Carbon budget in the serpentine area and non-serpentine area were absorbs 5.3, $14.49ton{\cdot}Cha^{-1}yr^{-1}$, respectively.

• International Area Studies Review
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• v.21 no.4
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• pp.247-268
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• 2017

This paper analyzes for companies of 2011~2014 the effects of corporate social responsibility on audit efficiency. Using KEJI Index and its individual components which is published by Citizens' Coalition for Economic Justice Institute, this paper analyzes their effects on audit efficiency of audit fees and audit hours. The results of analyses are as followings. First, corporate social responsibility(CSR) composite index did not show any significant relationship between audit fees and audit hours. However, for analyses of the effects of CSR individual components on audit efficiency, variable such as CSR fairness(CSR2), CSR social contribution(CSR3), CSR environmental protection activity(CSR5) have the negative effects on the audit fees and audit time. and CSR customer protection(CSR4), CSR employee satisfaction(CSR6) have the positive effects on the audit fees and audit time. Results suggest that independent auditors may reduce audit risks associated with possible misrepresentation of financial statements for companies with high scores of CSR fairness (CSR2), CSR social contribution(CSR3), and CSR environmental protection activity(CSR5). Also, financial statement auditors may perceive surge of discretionary expenses, and set audit risk high for companies with CSR customer protection(CSR4), and CSR employee satisfaction(CSR6). Together, KEJI Index and its individual components appear to have differential effects on audit efficiency.

• Management & Information Systems Review
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• v.38 no.2
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• pp.1-28
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• 2019

The purpose of this study is to empirically analyze the effects of characteristics of Leader (authoritarian disposition, procedural justice, job instability) on the organizational commitment of subordinates through abusive supervision and leader-member exchange(LMX). To this end, a survey was performed on the employees under the manager level in a large enterprise in Korea. The results of this study are as follows. First, the Hypothesis 1, 2, and 3 that the characteristics of leader (authoritarian disposition, procedural justice, job instability) will make effects on the organizational commitment of subordinates through abusive supervision were adopted. Second, in the hypotheses that the characteristics of leader (authoritarian disposition, procedural justice, job instability) will make effects on the organizational commitment of subordinates through LMX, Hypothesis 4 of authoritarian disposition, and Hypothesis 6 of job instability were rejected, while only Hypothesis 5 of procedural justice was adopted, as it made effects on the organizational commitment of subordinates through LMX. Third, the Hypothesis 7, 8, and 9 that the characteristics of leader (authoritarian disposition, procedural justice, job instability) will make effects on the organizational commitment of subordinates through abusive supervision and LMX were all adopted. This study is meaningful, in that it identified the structural relationship that the characteristics of leader make effects on the organizational commitment of subordinates through abusive supervision and LMX. It is expected that the results of this study can be used as base materials for new studies on abusive supervision which have been made in diversified ways in Korea and overseas.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.13-19
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• 2019

After the Fukushima nuclear accident, a new power supply using a lithium polymer battery has been proposed the first time in the world as the safety of the emergency battery facility has been required. It is required to have the safety of the rack system in which the battery device is installed in order to apply the proposed technology to the field. Therefore, the purpose of this study is to evaluate the seismic performance of string and rack frame for lithium-polymer battery devices developed for the first time in the world to satisfy 72 hours capacity. (1) The natural frequency of the unit rack system was 9 Hz, and the natural frequency before and after the earthquake load did not change. This means that the connection between members is secured against the design earthquake load. (2) he vibration reduction effect by string design was about 20%. (3) As a result of the seismic performance test under OBE and SSE conditions, the rack frame system was confirmed to be safe. Therefore, the proposed rack system can be applied to the nuclear power plant because the rack system has been verified structural safety to the required seismic forces.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.363-371
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• 2019

In this study, 340 Korean women were surveyed to analyze the impact of the type of sunscreen and use status on the satisfaction of products and resale. Studies have shown that indoor activity is higher than outdoor activity, and both simple and complex sunscreen is often used to compensate for skin tone. Out of single sunscreen, sun cream was used and air cushion was used a lot. Although product usability and UV protection indices were important factors in purchasing, 30% experienced side effects while product satisfaction and willingness to repurchase were high. The recognition of safety, Effectiveness, convenience, usability, satisfaction, and repurchase were all higher than that of composite UV-blocking products, and among subcomponents of product usage recognition, the level of convenience, efficacy, usability, and safety affected satisfaction and repurchase in order. Consequently, the perception of simple UV protection products was higher when using products for UV protection, and its convenience had a significant impact on satisfaction and resale.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.267-274
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• 2019

The purpose of this study is to investigate the effect of a practiced aquatic exercise program on the body function of obese women in the community, with knowledge of obesity preceded by obesity management education. The subjects were 20 obese women aged 51 to 79 who participated in the program for 8 weeks among the participants of health program in S healthcare center in D city. The aquatic exercise program, which includes obesity management training, consists of a total of 110 minutes, including twice a week, 20 minutes of obesity management training, and 60 minutes of aquatic exercise program. Obesity management education focuses on physical activity practice and dietary training. The results of this study showed that the aquatic exercise program including the 8 - week obesity management training decreased abdominal circumference, body weight and body mass index (p <.001, p <.001, p <.001),increased grip strength(P <.05), which is an effective program for reducing obesity and improving muscle power. In the follow-up study, it is necessary to increase the number of subjects and to develop the experimental design study with the control group and the participatory obesity management underwater exercise program that the participant directly participates and leads. It also suggests that additional strategies for continuous lifestyle improvement are needed.