• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.649-652
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• 2013

LEON3 is a 32-bit synthesisable processor based on the SPARC V8. It can be connected to AMBA 2.0 bus and has a 7-stage pipeline, IEEE-754 FPU and 256[KB] cache. It can be easily implemented using FPGA and used for a SoC design. DSU which comes with LEON3 can be used to control and monitor the operation of LEON3. And DSU makes it easy to set a debugging environment for the development of both hardware and software for an embedded systems based on LEON3. This paper presents the summary of the development of LEON3 monitoring software.

• Journal of Institute of Control, Robotics and Systems
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• v.20 no.4
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• pp.474-479
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• 2014

LEON3 is a 32-bit synthesizable processor based on the SPARC V8. It can be connected to AMBA 2.0 bus and has a 7- stage pipeline, IEEE-754 FPU and 256[KB] cache. It can be easily implemented using FPGA and used for a SoC design. DSU which comes with LEON3 can be used to control and monitor the operation of LEON3. And DSU makes it easy to set a debugging environment for the development of both hardware and software for an embedded systems based on LEON3. This paper presents the summary of the debugging tool for LEON3 based embedded systems. The debugging tool can initialize the target hardware, find out how the target hardware is configured, load application code to a specified memory space and run that application code. To provide users a debugging environment, it can set breakpoints and control the operation of LEON3 correspondingly. And function call trace is one of key functions of the debugging tool.

• Parasites, Hosts and Diseases
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• v.60 no.3
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• pp.217-221
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• 2022

The head louse Pediculus humanus capitis (De Geer) is a hematophagous ectoparasite that inhabits the human scalp. The infestations are asymptomatic; however, skin irritation from scratching occasionally may cause secondary bacterial infections. The present study determined the presence and frequency of the knockdown resistance (kdr) mutation T929I in 245 head lice collected from Mexico, Peru, and Canada. Head lice were collected manually using a comb in the private head lice control clinic. Allele mutation at T9291 was present in 100% of the total sampled populations (245 lice) examined. In addition, 4.89% of the lice were homozygous susceptible, whereas 6.93% heterozygous and 88.16% homozygous were resistant, respectively. This represents the second report in Mexico and Quebec and fist in Lima.

• Archives of Plastic Surgery
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• v.48 no.6
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• pp.723-723
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• 2021

• Bulletin of the Korean Space Science Society
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• 2009.10a
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• pp.46.1-46.1
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• 2009

현재 개발 중인 탑재컴퓨터의 메인 프로세서는 MCMERC32SC를 사용하고 있으며, 탑재소프트웨어를 개발하기 위하여 Gaisler Reserach사에서 개발된 소프트웨어 기반의 TSIM-ERC32 에뮬레이터를 이용하여 실시간 위성 시뮬레이터를 개발되어 탑재소프트웨어 개발 및 검증에 사용하였다. 차세대 저궤도 위성 탑재 컴퓨터의 메인 프로세서는 현재 LEON2/3이 사용되고 있으며, LEON2/3 프로세서를 모사해주는 소프트웨어 기반의 에뮬레이터의 경우 LEON2/3의 높은 성능 때문에 실시간 성능을 만족시키지 못하는 문제를 가지고 있다. 현재 ESA에서는 이 문제를 해결하기 위하여 하드웨어 기반의 프로세서 에뮬레이터를 개발/사용하고 있으며, 또 다른 방식으로 기존 프로세서 에뮬레이터가 interpretation방식을 사용한 반면 dynamic translation방식의 에뮬레이터를 개발하여 5~10배 이상의 성능 향상을 통해 실시간 성능을 만족시키고 있다. 이 논문에서는 현재 사용 중인 ERC32 프로세서를 dynamic translation emulation 기법을 사용하여 프로세서 에뮬레이터 개발 방법과 현재 상황에 대해서 설명하며, 추후 LEON2/3를 위한 에뮬레이터 개발의 가능성에 대해서 설명한다.

• Archives of Plastic Surgery
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• v.48 no.5
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• pp.518-523
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• 2021

Epignathus is a rare congenital orofacial teratoma that arises from the sphenoid region of the palate or the pharynx. It occurs in approximately 1:35,000 to 1:200,000 live births representing 2% to 9% of all teratomas. We present the case of a newborn of 39.4 weeks of gestation with a tumor that occupied the entire oral cavity. The patient was delivered by cesarean section. Oral resection was managed by pediatric surgery. Plastic surgery used virtual 3-dimensional models to establish the extension, and depth of the tumor. Bloc resection and reconstruction of the epignathus were performed. The mass was diagnosed as a mature teratoma associated with cleft lip and palate, nasoethmoidal meningocele that conditions hypertelorism, and a pseudomacrostoma. Tridimensional technology was applied to plan the surgical intervention. It contributed to a better understanding of the relationships between the tumor and the adjacent structures. This optimized the surgical approach and outcome.

• Journal of Korean Neurosurgical Society
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• v.60 no.1
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• pp.60-66
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• 2017

Objective : Sacral insufficiency fracture (SIF) contributes to severe low back pain. Prolonged immobilization resulting from SIF can cause significant complications in the elderly. Sacroplasty, a treatment similar to vertebroplasty, has recently been introduced for providing pain relief in SIF. The purpose of this study is to investigate the clinical short-term effects of percutaneous sacroplasty on pain and mobility in SIF. Methods : This study is conducted prospectively with data collection. Sixteen patients (3 men and 13 women) with a mean age of 77.5 years (58 to 91) underwent sacroplasty. Patients reported visual analogue scale (VAS; 0-10) and Oswestry disability index (ODI; 0-100%) scores. VAS and ODI scores were collected preoperatively and again at one day, one month, and three months postoperatively. Questionnaires measuring six activities of daily living (ADLs) including ambulating, performing housework, dressing, bathing, transferring from chair, and transferring from bed were collected. Ability to perform ADLs were reported preoperatively and again at three months postoperatively. Results : The mean preoperative VAS score ($mean{\pm}SD$) of $7.5{\pm}0.8$ was significantly reduced to $4.1{\pm}1.6$, $3.3{\pm}1.0$, and $3.2{\pm}1.2$ postoperatively at one day, one month, and three months, respectively (p<0.01). The mean ODI score (%) also significantly improved from $59{\pm}14$ preoperatively to $15.5{\pm}8.2$ postoperatively at one month and $14.8{\pm}8.8$ at three months (p<0.01). All ADL scores significantly improved at three months postoperatively (p<0.01). Conclusion : Percutaneous sacroplasty alleviates pain quickly and improves mobility and quality of life in patients treated for SIF.

• IEMEK Journal of Embedded Systems and Applications
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• v.14 no.1
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• pp.51-61
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• 2019

There are strict evaluation processes before using new processors to satellites. Engineers evaluate processors from various viewpoints including specification, development environment, and cost. From a viewpoint of computation power, manufacturers provide benchmark results with processors, and engineers decide which processors are adequate to their satellites by comparing the benchmark results with requirements of their satellites. However, the benchmark results depends on a test environment of manufacturers, and it is quite difficult to achieve similar performance in a target environment. Therefore, it is necessary to evaluate the processors in the target environment. This paper compares performance of a processor, AT697F/LEON2, in software testbed (STB) with three development boards of XC2V/LEON3, GR712RC/LEON3, and GR740/LEON4. Seven benchmark functions of Dhrystone, Stanford, Coremark, Whetstone, Flops, NBench, and MiBench are selected. Results are analyzed with hardware and software properties: hardware properties of core architecture, number of cores, cache, and memory; and software properties of build options and compilers. Based on the analysis, this paper describes a guideline for choosing processors for next generation satellites.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.1
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• pp.49-59
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• 2021

Background: To evaluate changes in the effectiveness of phentolamine mesylate in combination with different local anesthetics (LAs) and vasoconstrictors. A prospective randomized double-blind study was conducted with 90 patients divided into three groups, with each group being administered one of three different LAs: lidocaine 2% 1/80,000, articaine 4% 1/200,000, and bupivacaine 0.5% 1/200,000. Methods: We compared treatments administered to the mandible involving a LA blockade of the inferior alveolar nerve. Results were assessed by evaluating reduction in total duration of anesthesia, self-reported patient comfort using the visual analog pain scale, incidence rates of the most common adverse effects, overall patient satisfaction, and patient feedback. Results: The differences among the three groups were highly significant (P < 0.001); time under anesthesia was especially reduced for both the lip and tongue with bupivacaine. The following adverse effects were reported: pain at the site of the anesthetic injection (11.1%), headaches (6.7%), tachycardia (1.1%), and heavy bleeding after treatment (3.3%). The patients' feedback and satisfaction ratings were 100% and 98.9%, respectively. Conclusions: Efficient reversal of LAs is useful in dentistry as it allows patients to return to normal life more readily and avoid common self-injuries sometimes caused by anesthesia. Phentolamine mesylate reduced the duration of anesthesia in the three studied groups, with the highest reduction reported in the bupivacaine group (from 460 min to 230 min for the lip and 270 min for the tongue [P < 0.001]).

• Parasites, Hosts and Diseases
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• v.61 no.4
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• pp.405-417
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• 2023

Chagas disease, caused by Trypanosoma cruzi parasite, is a significant but neglected tropical public health issue in Latin America due to the diversity of its genotypes and pathogenic profiles. This complexity is compounded by the adverse effects of current treatments, underscoring the need for new therapeutic options that employ medicinal plant extracts without negative side effects. Our research aimed to evaluate the trypanocidal activity of Bidens pilosa fractions against epimastigote and trypomastigote stages of T. cruzi, specifically targeting the Brener and Nuevo León strains-the latter isolated from Triatoma gerstaeckeri in General Terán, Nuevo León, México. We processed the plant's aerial parts (stems, leaves, and flowers) to obtain a methanolic extract (Bp-mOH) and fractions with varying solvent polarities. These preparations inhibited more than 90% of growth at concentrations as low as 800 ㎍/ml for both parasite stages. The median lethal concentration (LC₅₀) values for the Bp-mOH extract and its fractions were below 500 ㎍/ml. Tests for cytotoxicity using Artemia salina and Vero cells and hemolytic activity assays for the extract and its fractions yielded negative results. The methanol fraction (BPFC3MOH1) exhibited superior inhibitory activity. Its functional groups, identified as phenols, enols, alkaloids, carbohydrates, and proteins, include compounds such as 2-hydroxy-3-methylbenzaldehyde (50.9%), pentadecyl prop-2-enoate (22.1%), and linalool (15.4%). Eight compounds were identified, with a match confirmed by the National Institute of Standards and Technology (NIST-MS) software through mass spectrometry analysis.