• 한국환경과학회지
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• 제28권12호
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• pp.1101-1110
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• 2019

This study investigated Post-Occupancy Evaluation (POE) of cherry blossom trails 'Cherry Road' in Daegu Catholic Univ. campus, at Gyeonsan-city, Korea. The evaluation focused on image preference and satisfaction of users i.e., students, using questionnaire surveys. A total 201 questionnaire samples were analyzed and most of the respondents were in the age group of 20. Frequency analysis was conducted on demographics, use behavior, reliability, and means. Factor analysis and multiple regression analysis were conducted for user satisfaction and image preference. Over 80% of visitors came with companions during daytime. The most common motives for use were strolling and walking, event and meeting, passing. For user satisfaction the mean scores were highest for landscape beauty (4.22), image improvement (4.14), campus image (4.08). Night lighting facility received the lowest score (3.32). Factor analysis concerning user satisfaction was categorized into environment-human behavior and physical factors. Multiple regression analysis showed that the overall satisfaction of user was significantly influenced by five independent variables: 'harmonious' (β=.214), 'night lighting facility' (β=.173), 'landscape beauty' (β=.208), 'lawn care' (β=.154), and 'walking trails' (β=.123). The mean scores of image variables were highest for 'beautiful' (5.81), 'bright' (5.67), and 'open' (5.64). The lowest scores was for 'quiet' (4.47). Exploratory factor analysis led to three factors being categorized: aesthetics, comforts, and simplicity. Result of multiple regression analysis indicated that the preference of space image was significantly influenced by five variables: 'bright' (β=.397), 'refreshing' (β=.211), 'cool' (β=.219), 'clean' (β=.182), and 'natural' (β=.-142). Hence, Cherry Road has a high level of user satisfaction and image evaluation, which is interpreted as having various cultural events and value for students on campus. To improve the satisfaction of Cherry Road in the future, it is necessary to secure night lighting, to manage trash cans, and to secure rest space.

• 대한족부족관절학회지
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• 제14권1호
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• pp.36-40
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• 2010

Purpose: To investigate the results of surgical treatment of the symptomatic accessory navicular in adolescent. Materials and Methods: 11 patients who were 11-16 years old with symptomatic accessory navicular were identified between 2001 and 2009. Six cases were diagnosed after trauma and 8 cases were diagnosed by accident with painful bony protrusion on medial aspect of foot. In cases after at least 3 months of ineffective conservative treatment, patients were treated by resection of accessory navicular and reattachment of tibialis posterior tendon to the apex of the medial longitudinal arch using periosteum and ligamentous soft tissue without transposition of its course. And then short leg cast was applied for correction of the flat foot (if it is combined) which was molded into the longitudinal arch with the talonavicular joint released and foot inverted during about 6 weeks. Results: All were type II accessory navicular without tibialis posterior tendon lesions. In most cases pain was improved, results were excellent in seven and good in four. Calcaneal pitch angle and talus-first metatarsal angle was improved about $4.64^{\circ}$ and $5.79^{\circ}$ in average. Conclusion: Symptomatic accessory navicular in adolescent might not be associated with the tibialis posterior tendon lesions. The surgical treatment composed of excision of the accessory navicular with simple replication of the tibialis posterior tendon without altering its course led to good results in most cases. The procedure has a low rate of complications. And it is easy to be performed with a good satisfaction.

• 한국의류산업학회지
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• 제19권1호
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• pp.49-60
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• 2017

In this study, change trends and specific times for change in body size were sought to be identified by using manual measurements for Korean adult women at 20 to 89 of age, along with examinations of change trends and specific times of change in body shape based on body index values. The examinations of means, deviations, and variation coefficients revealed that there was a tendency of most height related measures to decrease. In addition, combined with decrease in height, growth in weight led to increased BMI, thus resulting in increase in measures of circumference, thickness, and breadth in the torso area. The BMI trends showed that with increasing age, BMI increased, reaching the peak between the ages of 55 and 59 and then decreasing from 64 of age, with the steepest increase in BMI at ages from 50 to 54. The examination of differences in the body flatness ratio for different parts of body found that with increasing age the ratio decreased, indicating a tendency for gradual change to round body shapes. The analysis of 3D body shape found that there were more back-bends and lowered shoulder levels with age, accompanied with a tendency for more bended legs and more inclined-forward necks. The key trends in changes in body measurements by age and detailed estimates of 3D standard body shape drawn out from this study are expected to significantly contribute to establishing a basic database for generating patterns reflecting age features of Korean adult females.

• 한국산업보건학회지
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• 제26권4호
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• pp.404-410
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• 2016

Objectives: This study aimed to examine and analyze the material safety data sheet(MSDS) information for photoresist chemicals used in certain processes in semiconductor plants. Methods: After collecting MSDS for 178 chemical products currently used in certain processes in semiconductor plants, we analyzed Sections 2, 3, 11, and 15 of each MSDS with reference to the guidelines for evaluating the reliability of MSDS provided by the Korea Occupational Safety and Health Agency. In addition, we reviewed the recorded uses and the ratios of trade secrets. Results and Conclusions: We studied a total of 178 chemical products. An MSDS was available for 176(98.9%) of them and all adhered to the Globally Harmonized System(GHS) regulations. There were 37 cases of errors in Hazard Identification, pertaining to 20.8% of all products surveyed. There were 64 cases of errors in the current legal circumstances, pertaining to 36.0% of all products. There were a total of 407 trade secrets across 52.2% of products. We believe that a government-led education and certification system needs to be introduced to improve the transfer of MSDS information. The government, chemical manufacturers and suppliers all need to make an effort to produce reliable MSDS.

• Journal of Animal Science and Technology
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• 제51권6호
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• pp.527-536
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• 2009

A potent protein degrading bacterium was isolated from soil samples of different environments. Polyphasic taxonomic studies and phylogenetic 16S rRNA sequence analyses led to identify the isolate IB No. 11 as a strain of Bacillus subtilis. The isolated strain was recognized to produce protease constitutively, and the maximum production (1.64 units/ml) was attained in a shake flask culture when the isolate was grown at $40^{\circ}C$, for 32 h in basal medium supplemented with starch (0.25%) and gelatin (1.25%) as sole carbon and nitrogen source, respectively. The optimum pH and temperature for the protease activity were determined to be pH 7.0 and $50^{\circ}C$, respectively. $Ca^{2+}$ and $Mn^{2+}$ enhanced remarkably the protease activity but neither showed positive effect on the protease's thermal stability. In addition, it was observed that the protease was fairly stable in the pH range of 6.5-8.0 and at temperatures below $50^{\circ}C$, and it could be a good candidate for an animal feed additive. The inhibition profile of the protease by various inhibitors indicated that the enzyme is a member of serine-proteases. A combination of UV irradiation and NTG mutagenesis allowed to develop a protease hyper-producing mutant strain coded as IB No. 11-4. This mutant strain produced approximately 3.23-fold higher protease activity (6.74 units/mg) than the parent strain IB No. 11 when grown at $40^{\circ}C$ for 32h in the production medium. The protease production profile of the selected mutants was also confirmed by the zymography analysis.

• 한국식품영양학회지
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• 제27권3호
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• pp.495-506
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• 2014

This study was conducted to measure the effect of a community-based nutritional intervention program on dietary behaviors and nutrient intakes of low-income elderly women in Korea. The subject of the study was a group of 88 elderly women using the free meal service in Dong-gu, Gwangju city in Korea. The study was carried out from April to July 2009, and the pretest, application of nutrition education, and post-test were applied in each stage. This community-based nutrition intervention program consisted of snack supplement and nutrition education provided three times a week and 36 times in total. The nutrition education was led by the nutritionists and professionals using various educational media. Snack supplement included were milk, soymilk, carrot juice, bread, yogurt, and bananas. The result of pretest showed that the nutrient intakes of the subjects were much below the Recommended Nutrient Intake (RNI) level of Dietary Reference Intake for Koreans. Comparison of the dietary behavior score and nutrient intakes before and after the nutritional intervention program indicated that the food behavior score increased from 3.1 to 5.6 (P<0.001) and intake of energy, protein, carbohydrate, thiamin, niacin, vitamin C, iron, and potassium of the subjects all increased significantly (P<0.05). Mean Adequacy Ratio (MAR) of their nutrient intakes was also improved from 0.53 to 0.64 (P<0.01). These results indicated that the nutrition intervention program conducted in this study was effective in improving dietary behavior and nutrient intakes of elderly women in local community.

• 한국사회복지학
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• 제64권4호
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• pp.5-29
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• 2012

본 연구는 자살로 자녀를 잃은 부모의 경험을 이해하고자 한 것이다. 12명의 부모를 심층면접 하였으며 속담, 소설 등의 실존적 탐구를 사용하였다. 도출된 본질적 주제는 '넋이 나감, 참척죄인, 유형의 땅과 정지된 생애 시간, 고통을 위로받고 싶음, 반쯤 꿰맨 상처로 살아지는 날들'로 드러났다. 부모로서 자녀를 지키지 못했다는 죄책감과 충격에 부모 스스로 사회적 고립화를 자처하고 자살유혹, 우울, PTSD 등의 애도반응이 나타나고 있다. 특히 문화적 특성에서 한국의 부모들은 자녀 자살의 원인을 전적으로 부모의 탓으로 돌리고, 자살은 집안체면을 깎는 부끄러운 수치라고 보며, 자살을 개인이나 집안의 문제로만 보고 있다. 이러한 결과를 중심으로 자살 고위험군인 부모들을 지원하기 위한 실천적 제언을 하였다.

• 한국축산식품학회지
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• 제40권5호
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• pp.710-721
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• 2020

This study dealt with the use of quinoa flour (QF) or teff flour (TF) as partial beef fat replacers in the formulation of emulsion-type sausages. A control (C) group was manufactured with 20% beef fat, while the other three groups were formulated with 10% beef fat plus 5% QF (Q), 5% TF (T), and 2.5% QF+2.5% TF (QT). Water-holding capacity of the emulsions was higher in Q (81.81%), T (82.20%), and QT (84.10%) samples than in C (64.83%) samples. Total expressible fluid and expressible fat were the lowest in Q and T samples, indicating the highest emulsion stability of those groups. Incorporation of QF and TF into formulations increased moisture and carbohydrate contents while decreased fat and energy values. Besides, the use of QF was effective to increase protein and dietary fiber contents. T sausages had lower luminosity (L^⁎) and higher yellowness (b^⁎) than C sausages, whilst Q sausages did not result in significant color changes. Higher cook yield values were recorded in Q (97.96%), T (98.21%), and QT (98.15%) samples compared with C (96.44%) samples. Inclusion of QF and TF to formulation led to lower hardness and gumminess, while utilization of TF was also effective to decrease chewiness. Consequently, healthier emulsified sausages were obtained by the inclusion of QF or TF that could decrease the fat content more than 50% without sacrificing overall quality, bringing advantages by quinoa over teff for increasing nutritional value and leading minimal modifications on color and texture.

• Bulletin of the Korean Chemical Society
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• 제32권10호
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• pp.3675-3681
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• 2011

Fusarium oxysporum, an important pathogen that mainly causes vascular or fusarium wilt disease which leads to economic loss. Disruption of gene encoding a heterotrimeric G-protein-${\beta}$-subunit (FGB1), led to decreased intracellular cAMP levels, reduced pathogenicity, colony morphology, and germination. The plant defense protein, Nicotiana alata defensin (NaD1) displays potent antifungal activity against a variety of agronomically important filamentous fungi. In this paper, we performed a molecular modeling and docking studies to find vital amino acids which can interact with various antifungal compounds using Discovery Studio v2.5 and GRAMMX, respectively. The docking results from FGB1-NaD1 and FGB1-antifungal complexes, revealed the vital amino acids such as His64, Trp65, Ser194, Leu195, Gln237, Phe238, Val324 and Asn326, and suggested that the anidulafungin is a the good antifungal compound.The predicted interaction can greatly assist in understanding structural insights for studying the pathogen and host-component interactions.

• Journal of Ginseng Research
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• 제44권1호
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• pp.67-78
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• 2020

Background: Gintonin (GT), a novel ginseng-derived exogenous ligand of lysophosphatidic acid (LPA) receptors, has been shown to induce cell proliferation and migration in the hippocampus, regulate calcium-dependent ion channels in the astrocytes, and reduce β-amyloid plaque in the brain. However, whether GT influences autophagy in cortical astrocytes is not yet investigated. Methods: We examined the effect of GT on autophagy in primary cortical astrocytes using immunoblot and immunocytochemistry assays. Suppression of specific proteins was performed via siRNA. LC3 puncta was determined using confocal microscopy. Results: GT strongly upregulated autophagy marker LC3 by a concentration- as well as time-dependent manner via G protein-coupled LPA receptors. GT-induced autophagy was further confirmed by the formation of LC3 puncta. Interestingly, on pretreatment with an mammalian target of rapamycin (mTOR) inhibitor, rapamycin, GT further enhanced LC3-II and LC3 puncta expression. However, GT-induced autophagy was significantly attenuated by inhibition of autophagy by 3-methyladenine and knockdown Beclin-1, Atg5, and Atg7 gene expression. Importantly, when pretreated with a lysosomotropic agent, E-64d/peps A or bafilomycin A1, GT significantly increased the levels of LC3-II along with the formation of LC3 puncta. In addition, GT treatment enhanced autophagic flux, which led to an increase in lysosome-associated membrane protein 1 and degradation of ubiquitinated p62/SQSTM1. Conclusion: GT induces autophagy via mTOR-mediated pathway and elevates autophagic flux. This study demonstrates that GT can be used as an autophagy-inducing agent in cortical astrocytes.