• Korean Journal of Agricultural and Forest Meteorology
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• v.19 no.3
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• pp.102-109
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• 2017

A temperature-based Beta function model was developed for corn hybrids (Zea mays L.). The beta function based on the hourly temperature was fitted to the phenology data (silking date) obtained for six years from 2008 through 2013 at four survey sites. Using the Beta function model, silking dates for two corn hybrids with the different ecotype ('Danok3', 'Ilmichal') were estimated over two years from 2014 through 2015 at four sites, and then the performance of the model was evaluated based on the data for the same period. The silking dates estimated by the model were predicted earlier than those observed at survey sites. Still, the correlation between estimates and observation was relatively high (r=0.859). The accuracy of the model differed by the survey site and the year, which was likely due to the considerably large standard deviation of the parameter calibrated in this study.

• Journal of Yeungnam Medical Science
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• v.16 no.1
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• pp.69-75
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• 1999

Imidapril(Tanatril$^{(R)}$), a newly developed ACE inhibitor, has been used to treat hypertension and congestive heart failure. This study was designed to assess the antihypertensive effect and safety of Imidapril(Tanatril$^{(R)}$) in patients with essential hypertension. 5-10mg of imidapril(Tanatril$^{(R)}$) was administered once a day in 30 patients with essential hypertension and followed up for 8 weeks. We tested the drug's effectiveness, safety, and the incidence of imidapril induced dry coughs. After 8 weeks of treatment with imidapril, 76.2%(16/21) of patients showed lowered blood pressure and 47.6% showed normal blood pressure. The overall incidence of adverse effects was 33.3%(7/21), and among these adverse effects, dry cough was shown in only 9.5%. Thus, we concluded that imidapril(Tanatril$^{(R)}$) is as safe and effective as other ACE inhibitors, especially with imidapril showing very little incidence of dry cough compared to other ACE inhibitors.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.18 no.3
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• pp.97-107
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• 2015

Research was initiated to investigate a vegetation characteristics of the species of ground cover plants mixed with herbeceous and woody plants on a cut slope. 4 different ground cover plants (Miscanthus sinensis var. purpurascens, Pennisetum alopecuroides, Festuca arundinacea and Zoysia japonica) were seeded at the same rate of $10.0g/m^2$ with herbaceous plants (Lotus corniculatus var. japonicus, Dianthus sinensis, Aster yomena, Chrysanthemum zawadskii and Coreopsis drummondii L) at the total seeding rate of $7.5g/m^2$ and native woody plants (Lespedeza bicolor Turcz, Indigofera pseudo-tinctoria and Albizzia julibrissin) at the total seeding rate of $7.5g/m^2$, respectively. This experiment was treated with 3 replications on a randomized block design. Data such as surface coverage rate(%), the germinating number, plant height and visual quality were analyzed. There were no statistic differences observed in the soil hardness and the soil moisture content while a significant difference was observed in the surface coverage rate and the germinating number. The surface coverage rate and the germinating number were significantly high in the Pennisetum alopecuroides plot when compared with the Miscanthus sinensis var. purpurascens plot, the Festuca arundinacea plot and the Zoysia japonica plot, respectively from the viewpoint of ground covers. Especially, the surface coverage rate was considerably low in the Festuca arundinacea plot. However, the surface coverage rate and the germinating number were no statistic differences observed in this treatment from the viewpoint of herbaceous and woody plants. Also, both of the plant height and visual quality were high in the Pennisetum alopecuroides plot when compared with the Miscanthus sinensis var. purpurascens plot, the Festuca arundinacea plot and the Zoysia japonica plot, respectively. We concluded that Pennisetum alopecuroides was the optimum plant from the treated ground covers mixed with native woody and herbaceous plants for the balanced emergence from the viewpoint of the ecological slope vegetation.

• Applied Chemistry for Engineering
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• v.5 no.4
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• pp.616-623
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• 1994

Conductive Polypyrrole films have been synthesized by electrochemical method in nucleophilic solvent such as N, N-dimetylformamide(DMF), dimethylsulfoxide(DMSO). The effect of protic acid as supporting electrolyte to decrease the nucleophilicity of the solvent was studied. Cyclic voltammetry, I-t transients were carried out to investigate the electrodeposition of conductive polypyrrole film on platinum electrode. Three peaks of 0.65V, 0.85V, and 1.2V vs. $Ag/AgNO_3$ indicated oxidation of monomer, oxidation of pyrrole to the platinum electrode and decomposition of polypyrrole film, respectively. With the I-t transients, nucleation process was confirmed and from obtained linear fits of I vs.t2resembles the metal film formation, and 2.15-2.26 of n-value could be calculated. As concentration of pyrrole or prolic acid was increased, the conductivity of polypyrrole film increased linearly. Tensile strength and elongation were investigated for comparing the mechanical properties and also SEM was performed for morphology investigation.

• Korean Journal of Medicinal Crop Science
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• v.5 no.2
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• pp.91-94
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• 1997

This experiment was carried out to investigate the effects of black P.E. film mulching by different sowing dates on the growth and yield of Achyranthes japonia NAKAI. Emergence rate and the growth increment were increased in black polyethylene (P.E.) film mulching of sowing date at April 1. Dried root yield was highest by 3,190kg/ha in black P.E. film mulching and earlist sowing at April 1 with 20% increase compared to that of non mulching at April 1 planting.

• Korean Journal of Weed Science
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• v.15 no.2
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• pp.115-120
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• 1995

This experiment was conducted in the paddy field to investigate the influence of bensulfuron (methyl-2-[[[[[(4,6-dimethoxypyrimidin-2-yl)amino]carbonyl]amino]sulfonil]methyl]benzoate)+butachlor (N-(butoxymethyl)-2-chloro-2',6'-diethyl acetanilide) and bensulfuron+mefenacet(2-(1,3-benzothiazol-2-yloxy)-N-methylacetanilide) for seedling age of rice with Dongjinbyeo of medium-late-maturing variety, Hwaseongbyeo of medium-maturing variety and Namwonbyeo of early-maturing variety. Two herbicide applications interfered with the early growth of all rice varieties, the root was especially damaged more than the shoot. The phytotoxicity of bensulfuron+butachlor and bensulfuron+mefenacet was not significant statistically and the phytotoxicity of these herbicides for seedling age was apt to be similar, also. Twenty and 35days seedlings of Dongjinbyeo and Hawseongbyeo had more growth amount than 8days seedlings, but Namwonbyeo had opposite trend. The number of maximum tillers in the plots applied herbicides were fewer than untreated control but, the percentage of productive tillers was higher than those. Heading date for Namwonbyeo was delayed 2, 1-2 and 2-3days on 35, 20 and 8days seedlings by herbicide application, respectively.

• Journal of Microbiology
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• v.43 no.4
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• pp.345-353
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• 2005

The complex ecosystem of intestinal micro flora is estimated to harbor approximately 400 different microbial species, mostly bacteria. However, studies on bacterial colonization have mostly been based on culturing methods, which only detect a small fraction of the whole microbiotic ecosystem of the gut. To clarify the initial acquisition and subsequent colonization of bacteria in an infant within the few days after birth, phylogenetic analysis was performed using 16S rDNA sequences from the DNA iso-lated from feces on the 1st, 3rd, and 6th day. 16S rDNA libraries were constructed with the amplicons of PCR conditions at 30 cycles and $50^{\circ}C$ annealing temperature. Nine independent libraries were produced by the application of three sets of primers (set A, set B, and set C) combined with three fecal samples for day 1, day 3, and day 6 of life. Approximately 220 clones ($76.7\%$) of all 325 isolated clones were characterized as known species, while other 105 clones ($32.3\%$) were characterized as unknown species. The library clone with set A universal primers amplifying 350 bp displayed increased diversity by days. Thus, set A primers were better suited for this type of molecular ecological analysis. On the first day of the life of the infant, Enterobacter, Lactococcus lactis, Leuconostoc citreum, and Streptococcus mitis were present. The largest taxonomic group was L. lactis. On the third day of the life of the infant, Enterobacter, Enterococcus faecalis, Escherichia coli, S. mitis, and Streptococcus salivarius were present. On the sixth day of the life of the infant, Citrobacter, Clostridium difficile, Enterobacter sp., Enterobacter cloacae, and E. coli were present. The largest taxonomic group was E. coli. These results showed that microbiotic diversity changes very rapidly in the few days after birth, and the acquisition of unculturable bacteria expanded rapidly after the third day.

• FLOWER RESEARCH JOURNAL
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• v.19 no.3
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• pp.139-143
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• 2011

This research was conducted to figure out the effect of 1-methylcyclopropene, one of inhibitors of ethylene on the vase life of cut alstroemeria 'Alpine', snapdragon 'Fuji no Yuki', dahlia 'Toast, and lily 'Georgia'. Four kinds of cut flowers were treated with 250, 500, and 750 ppb of 1-MCP respectively for 12 hours. In case of cut alstroemeria, no significant difference was found between the untreated control and the treated ones in the days to flowering. The vase life in the treated ones, however, was extended for over two days, and the treated one with 250 ppb had the longest record with 17.1 days. In every treated ones of cut snapdragon, the remaining florets was more than that of the untreated control. The vase life showed, however, no difference. With the 1-MCP treatment, the vase life of cut dahlia was longer about two days than that of the untreated control. However, water uptake showed the opposite result. The vase life of cut lily showed no significant differences in all treatments. In case of water absorption, the treated one with 750 ppb uptaken more water by 3 ml.

• Archives of Pharmacal Research
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• v.24 no.6
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• pp.584-589
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• 2001

Isopropryl 2-(1-3-dithiethane-2-ylidene)-2 [N-(4-methyl-thiazole-2-yl) carbamoyl] acetate (YH439) is currently under phase ll clinical trials by the Yuhan Research Center for use as a hepatoprotective agent. Unfortunately, the oral bioavailbility of YH439, which is sparingly soluble in water (i.e., $0.3{\;}\mu\textrm{g}/ml{\;}or{\;}0.91{$\mu}M$ at room temperature), reportedly, is negligibleregardless of the dose administered to rats in the 10-300 mg/kg range. The bioavailability of the compound increased up to 24%, when administered in the form of a micellar solution ($700{\;}\mu\textrm{g}/ml$or 2.1 mM for YH439) at a dose of 10 mg/kg, suggesting that its limited solubility is associated with its negligible bioavailability. In order to obtain additional informmation concerning the bioavailability of YH439, the mechanism(s) involved in gastrointestinal (Gl) absorption were investigated in the present study. For this purpose, the transport of YH430 across a Caco-2 cell monolayer was measured in a $Transwell^{\circledR}$. A permeability of $4.07{\times}10^{-5}{\;}cm/s$ was obtained for the absorptive (i.e., apical to basolateral direction) transport of $0.42{\mu}M$ YH439, implicating that the in vivo Cl absorption is nearly complete. The absorptive transport exhibited a slight concentration-dependency with an intrinsic clearance ($CL_{i}$) of $0.38{\mu}L/{\textrm{cm}^2}/sec$, which accounted for 28.1% of the total intrinsic clearance (i.e., $CL_i$ plus the intrinsic clearance for the linear component) of the transport. Thus, saturation of the absorption process appears to be a minor factor in limiting the bioavailability of the compound. The apparent permeability of YH439 from the basolateral to the apical direction (i.e., efflux, $6.67{\times}10^{-5}{\;}cm/s$) was comparable to that for absorptive transport, but, interestingly, a more distinct concentration-dependency was observed for this transport. However, the efflux does not appear to influence the bioavailability of the compound, as evidenced by the sufficiently high permeability in the absorption direction. Rather, a reportedly extensive first-pass hepatic metabolism appears to be a principal factor in limiting the bioavailability. In this respect, reducing the first-pass metabolism by some means would lead to a higher bioavailability of the compound. Thus, elevation of the absorption rate of YH439 becomes a necessity. From a practical point of view, increasing the concentration of YH439 in the Cl fluid appears to be a feasible way to increase the absorption rate, because the compound is primarily absorbed via a linear mechanism. In summary, the solubilization of YH439, as previously demonstrated for a micellar solution of the compound, appears to be a practical way to increase the oral bioavailability of YH439.

• Food Engineering Progress
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• v.14 no.3
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• pp.235-242
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• 2010

This study was to investigate the combined effect of enzyme and trehalose addition on the retrogradation rate and quality changes in a Korean traditional rice cake, Backsulgi. As for the enzyme, a commercial maltogenic amylase, Novamyl, was used. From texture profile analysis and sensory tests, the optimum enzyme content for the preparation of Backsulgi was determined to be 0.1%. Backsulgi was prepared with the fixed content of Novamyl (0.1%) and different ratios (5, 10, 15%) of trehalose, and physicochemical and sensory properties were examined for 3 days of storage at ${25^{\circ}C}$. As trehalose content increased, the water activity of Backsulgi decreased. In Hunter's color value, L- and a-values of trehalose-added samples were significantly lower than those of control. In texture profile analysis, hardness of Backsulgi decreased with trehalose content. During storage, a increase in hardness and a decrease in cohesiveness were typically observed for all samples. However, those changes were significantly reduced with trehalose content. The retardation of retrogradation with the enzyme and trehalose addition was confirmed using calculated Avrami rate and time constants. These results revealed that combined treatments of 0.1% Novamyl and 10% trehalose could produce Backsulgi of better sensory quality with retarded retrogradation compared to separated treatment.