• 말소리와 음성과학
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• 제5권2호
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• pp.71-79
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• 2013

This study provided longitudinal examination of the Chinese learners' acquisition of the Korean vowels. Specifically the author examined whether Korean monophthongs are acquired rapidly in early stages of learning (Flege, Munro and Skelton, 1992; Munro and Derwing, 2008) or they develop rather gradually in proportion to the learners' experience (Byee, 2001; Ellis, 2006). This study collected the Korean vowel production by 23 Chinese learners for a year, and then analysed F1 and F2 of each Korean vowel. The results showed that 1) Most of the second language (L2) vowels were rapidly improved during the first six or nine months of Korean learning before reaching the constant stage; and 2) The exact acquisition trajectories varied across the seven vowels. Specifically the vowels which were acquired in the early stage of learning were /i, e, ɨ/ for F1 and /ʌ, e, o, u/ for F2. Thus this study supports the hypothesis of Flege et al. (1992) and Munro and Derwing (2008) except the fact that each vowel showed the different learning route.

• Journal of Nutrition and Health
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• 제4권4호
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• pp.39-46
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• 1971

Iso-butyl bromide의 합성을 시작으로 D.L-1-amino-3-methylbutylphosphonic acid의 합성을, Diethyl phophite의 합성을 시작으로 D.L-1-amino-2-phenyl ethylphosphonic acid의 합성을 하였다. 합성되어진 필수 아미노산인 Isoleucine analogue phosphonic acid는 각각 0.2%, 0.4%를 식이에 첨가했고 Phenylalanine analogue phosphonic acid는 0.35%와 0.7%를 각각 첨가하였으며 Standard-1과 Standard-2군과 비교군인 Isoleucine 0.2%와 0.4% Phenylalanine 0.35%와 0.7%군으로써 총 100마리의 숫쥐로 각 7주씩 14주의 사육 실험을 하였다. 동물 사육 기간내의 뇨채취와 사육후의 각 장기의 채취로써 총 질소와 P, glycogen측정을 시도하였다. 이러한 일련의 실험결과 (1) D.L-1-amino-3-methylbuthylphosphonic acid나D.L-1-amino-2-phenylethylphosphonic acid의 유기 합성에 있어서는 다 수율이 낮고 상당히 높은 융점을 보였으며 ${\alpha}-NH_2$기가 Ninhydrin 반응에 예민했다. (2) Aminophosphonic acid의 첨가군(D.L-1-amino-3-methylbutyl phosphonic acid, D.L-1-amino-2-Phenylethylphosphonic acid)에서나 Amino acid(Isoleucine, Phenylalanine)첨가군에 있어서 모든 장기의 무게, 총체내질소 보유율, 간장내 총단백질량과 인의양, 및 뇨를 통한 인의 배설량에 각각 큰 차이를 보이지 않았다. 이로 보아서 Phenylalanine Aminophosphonic acid나 Isoleucine aminophosphonic acid가 다 보통 아미노산인 Isoleucine이나 Phenylalanine에 못지않게 체내에서 이용됨이 밝혀졌다. (3) 그러나 Phenylalanine aminophosphonic acid 첨가군이 간의 glycogen 함량에 있어서 Phenylalanine 첨가군과 Standard군과 비교해 보았을때 높았으며 이는 통계적인 유의성을 나타냈다.(<0.05) 이는 Phenylalanine Aminophosphonic Acid가 active state로써 간내에서 쉽게 이용되어서 Tricarboxylic cycle의 intermediate로 incorporate되는 경향으로 생각 할 수 있다.

• 환경생물
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• 제41권4호
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• pp.427-438
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• 2023

Dichlofluanid는 해양환경 내 빠르게 분해되지만 농약 및 방오제로 사용되고 퇴적물에 쉽게 축적되어 지속적으로 해양환경으로 유입되고 있다. Dichlofluanid는 다양한 해양생물에게 독성영향을 미치는 것으로 알려져 있지만 해조류에 대한 독성연구는 충분히 보고되지 않았다. 따라서 우리나라의 주요 양식생물인 미역(Undaria pinnatifida) 암배우체의 생존율 및 상대성장률을 이용하여 dichlofluanid의 독성영향을 분석하였다. U. pinnatifida의 암배우체를 dichlofluanid (0, 1, 2, 4, 8, 16, 32 mg L^-1)에 노출하였고 암배우체 생존율의 무영향농도(NOEC), 최소영향농도(LOEC), 반수치사농도(LC₅₀)는 1, 2, 10.82(8.87~13.23) mg L^-1, 상대성장률의 NOEC, LOEC, 반수영향농도(EC₅₀)은 1, 2, 6.58 (6.03~7.17) mg L^-1로 분석되었다. 본 연구결과는 dichlofluanid에 대한 U. pinnatifida 암배우체의 독성영향을 평가하기 위한 중요한 참고자료로 활용될 것으로 기대된다.

• Child Health Nursing Research
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• 제30권1호
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• pp.7-16
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• 2024

Purpose: Children with cerebral palsy (CP) and their parents experience various problems that can affect their quality of life. This study examined factors affecting the quality of life of children with CP. Methods: A cross-sectional study was conducted in Yogyakarta, Indonesia, from January to August 2019. The participants were consecutively recruited children with CP aged 2 to 18 years and their parents. Ninety-eight children with CP and their parents, specifically their mothers, were recruited. Children's health-related quality of life (HRQoL) was measured using the Pediatrics Quality of Life Cerebral Palsy. Parental HRQoL and stress were measured using the WHOQOL-BREF and Parenting Stress Index (PSI). Results: Functional level V was the most common category for both Gross Motor Function Classification System (GMFCS) and Bimanual Fine Motor Function (BFMF) (35% and 28%, respectively). Children's mean HRQoL was medium (49.81±20.35). The mean total PSI score was high (94.93±17.02), and 64% of parents experienced severe stress. Bivariate analysis showed that GMFCS, BFMF, number of comorbidities, presence of pain, and parental stress were significantly correlated with the total score for children's HRQoL (p<.05). Multiple linear regression analysis (p<.05) demonstrated that more severe GMFCS and parental stress were associated with lower mean HRQoL scores in children. Conclusion: Factors including the level of GMFCS and parental stress affected the HRQoL of children with CP. Parental stress management should be included in the comprehensive management of these children.

• 한국CDE학회논문집
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• 제21권1호
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• pp.20-30
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• 2016

Recently immersive virtual reality (VR) becomes popular due to the advanced development of I/O interfaces and related SWs for effectively constructing VR environments. In particular, natural and intuitive manipulation of 3D virtual objects is still considered as one of the most important user interaction issues. This paper presents a comparative study on the manipulation and interaction of 3D virtual objects using different interfaces and interactions in three VR environments. The comparative study includes both quantitative and qualitative aspects. Three different experimental setups are 1) typical desktop-based VR using mouse and keyboard, 2) hand gesture-supported desktop VR using a Leap Motion sensor, and 3) immersive VR by wearing an HMD with hand gesture interaction using a Leap Motion sensor. In the desktop VR with hand gestures, the Leap Motion sensor is put on the desk. On the other hand, in the immersive VR, the sensor is mounted on the HMD so that the user can manipulate virtual objects in the front of the HMD. For the quantitative analysis, a task completion time and success rate were measured. Experimental tasks require complex 3D transformation such as simultaneous 3D translation and 3D rotation. For the qualitative analysis, various factors relating to user experience such as ease of use, natural interaction, and stressfulness were evaluated. The qualitative and quantitative analyses show that the immersive VR with the natural hand gesture provides more intuitive and natural interactions, supports fast and effective performance on task completion, but causes stressful condition.

• Clinical and Experimental Reproductive Medicine
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• 제43권1호
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• pp.44-50
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• 2016

Objective: This study was performed to assess our clinical experience with single-port access (SPA) laparoscopic cystectomy and myomectomy and the surgical outcomes of those procedures at our institution. Methods: The authors evaluated the surgical outcomes of SPA laparoscopic cystectomy in 293 patients and SPA laparoscopic myomectomy in 246 patients. The surgical outcomes comprised operation time, the amount of blood loss during the operation, the change in hemoglobin (before and after the operation), the change in hematocrit (before and after the operation), switching to the multi-port access method, complications, transfusions, and the duration of the postoperative hospital stay. Results: The Pearson correlation coefficient and the Spearman correlation coefficient between the operation time and the amount of blood loss were 0.312 and 0.321 for SPA laparoscopic cystectomy, respectively, and 0.706 and 0.674 for SPA laparoscopic myomectomy, respectively. The drops in hemoglobin and hematocrit were $1.33{\pm}0.78g/dL$ and $4.14%{\pm}2.45%$, respectively, in SPA laparoscopic cystectomy, while the corresponding figures were $1.34{\pm}1.13g/dL$ and $4.17%{\pm}3.24%$ in SPA laparoscopic myomectomy, respectively. Conclusion: This study reported the surgical outcomes of SPA laparoscopic cystectomy and myomectomy and compared them to previously published findings on traditional laparoscopic cystectomy and myomectomy. No significant differences were found in the surgical outcomes between SPA and traditional laparoscopic cystectomy and myomectomy.

• Journal of Chest Surgery
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• 제43권6호
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• pp.663-668
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• 2010

배경: 자연성 종격동 기종은 드문 질환으로 세계적으로 보고된 환자도 적다. 주로 젊은 남자에서 발병하며 양성의 자연 치유 경과의 질환으로 어떤 특별한 이유 없이 일어난다. 폐기포 파열을 일으키는 흉강내 압력 변화 이후 나타나게 된다. 두 병원의 임상 경험을 분석하여 적정한 치료에 도움이 되고자 한다. 대상 및 방법: 후향적으로 2003년 3월부터 2010년 8월까지 자연성 종격동 기종 환자들을 연구하였다. 결과: 24명의 환자가 자연성 종격동 기종으로 진단되었다. 이들 24명의 환자는 18명의 남자와 6명의 여자로 구성되었고, 평균 나이는 18.9세였다(범위 10~33살). 초기 주요 증상은 흉부 통증(79.2%), 이후 통증(62.5%), 피하 기종(4 1.7%)이었고 유발 인자로 운동(16.7%), 기침(12.5%), 구토(12.5%) 등이었고 유발 인자가 없는 경우가 54.2%였다. 모든 환자에서 흉부 단순 촬영과 단층 촬영이 이루어졌으며, 25% 환자에서 진단을 위해 단층 촬영이 필요하였다. 백혈구 수치와 C반응 단백(CRP)가 측정되었는데 초기 평균 수치는 각각 $9,790{\pm}3,240/{\mu}L$와 $1.31{\pm}1.71mg/dL$, 최종 평균 수치는 $5,440{\pm}1,665/{\mu}L$와 $0.72{\pm}0.73mg/dL$이었다. 23명의 환자가 입원하였으며(평균 $5.0{\pm}1.8$일) 증상은 자연 치유되었으며 합병증은 없었다. 결론: 자연성 종격동 기종은 약한 염증성 증세를 보이는 양성 질환이며 종종 흉부 또는 인후 통증을 나타낸다. 바람직하지 못한 결과를 방지하기 위하여 비침습적인 검사로 이차성 원인이 배제되어야 한다. 합병증과 재발이 거의 없는 관계로 증상에 따라 외래 진료나 단기적인 입원이 합당하다고 하겠다.

• 영어어문교육
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• 제13권2호
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• pp.91-108
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• 2007

This study investigates learners' perception on their engagement in rating activities in the EFL essay-writing context. The current study aims to address the answers to the following research questions: 1) What attitude do students show about their participation in the rating tasks? and 2) which of three aspects (e.g. the degree of rating experience, the exposure to English composition instruction and learning, and proficiency level) significantly influences learners' rating activities? 104 EFL learners participated in the rater training session. After participants finished rater training session, they rated three sample essays and peer essays using the given scoring guide. Based on the analysis of survey responses that students made, students showed positive attitude toward their engagement in rating tasks. For research question 2, only L2 writing proficiency seriously affected students' perception on the rating tasks. Advanced level of subjects did not feel stressed by a grade of peers as low level of subjects did. They were also critical about the benefits of self- and peer-assessment, suggesting that a peer's feedback on their own essay was not so useful and that a self-rating does not fully help learners identify their writing proficiency.

• 대한간호학회지
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• 제6권2호
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• pp.1-9
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• 1976

Presently, there is increasing demand for geriatric nursing care because of increasing preparation of elderly population due to extended age. Of particular importance in determining the effectiveness of nursing care given to the elderly is the attitude of the nurse toward the elderly patient. Knowledge of the various changes that usually occur with aging will enable the nurse to help an aged Person maximize his potential in illness and in health. The objectives of this study were : 1. To delineate the attitudes of nurses toward the geriatric nursing care. 2. To learn the influencing factors affecting the attitudes of nurses toward the geriatric nursing care. The study population defined and randomly selected is 225 nurses at one general hospital, one private hospital, two national hospitals in Seoul during the period of October l0th -20th, 1975. The questionnaire method was used. Respondents were 140 nurses. X$^2$- test and t- test were employed in analyzing the data. The questionnaire form included 54 statements which concerned the attitudes of nurses to-ward geriatric nursing care. It was divided into five areas : 1) General characteristics of study population. 2) The nurse's concepts of elderly. 3) Care of the geriatric patient. 4) Interpersonal relationship with geriatric patient. 5) Teaching of the geriatric patient. Each of the 54 statements of the questionnaire was considered to be either Positive or Negative. A Positive response was assigned the value of＋1 , and a Negative response or no response was assigned the value of O. The results of the study were as follows : 1. The Investigation of attitudes of nurses toward geriatric nursing care. a. Data indicated , respondents have negative attitudes in their. concepts of elderly (74.3%) b. Data indicated respondents have positive attitudes in care of geriatric patient (64.3%). c. Data indicated respondents have positive attitudes in interpersonal relationship with geriatric patient (85% ). 4. Data indicated respondents have positive attitudes in teaching of geriatric patient (89.3%). 2. The results of study regarding the five hypothesis were as follows : a There was significant difference in the mean scores between the attitudes of nurses toward the geriatric nursing care and level of education of the nurse. b. There was no significant difference between the attitudes of nurses toward the geriatric nursing care and clinical experience, but there was significant difference between care of the geriatric patient and clinical experience. c. There was no significant difference between the attitudes of nurses toward the geriatric nursing care and shift most frequently worked, but there was significant difference between care of the geriatric patient and shift most frequently worked. d. There was no significant difference in the mean scores between the attitudes of nurses toward the geriatric nursing care and marital status, but there was significant difference in the mean scores between interpersonal relationship, teaching of geriatric patient and marital status. e, There was no significant difference in the mean scores between the attitudes of nurses toward the geriatric nursing care and experience with elderly, but there was significant difference in the mean scores between care of geriatric patient and experience with elderly.

• 말소리와 음성과학
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• 제6권3호
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• pp.91-99
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• 2014

Although it is well documented that patients with cochlear implant experience hearing difficulties when processing their first language, very little is known whether or not and to what extent cochlear implant patients recognize segments in a second language. This preliminary study examines how Korean learners of English identify English segments in a normal hearing and cochlear implant simulation conditions. Participants heard English vowels and consonants in the following three conditions: normal hearing condition, 12-channel noise vocoding with 0mm spectral shift, and 12-channel noise vocoding with 3mm spectral shift. Results confirmed that nonnative listeners could also retrieve spectral information from vocoded speech signal, as they recognized vowel features fairly accurately despite the vocoding. In contrast, the intelligibility of manner and place features of consonants was significantly decreased by vocoding. In addition, we found that spectral shift affected listeners' vowel recognition, probably because information regarding F1 is diminished by spectral shifting. Results suggest that patients with cochlear implant and normal hearing second language learners would experience different patterns of listening errors when processing their second language(s).