• Biomolecules & Therapeutics
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• v.11 no.1
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• pp.1-4
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• 2003

Plants are known as important source in the search for new drugs. The twelve compounds from Viscum album (Loranthaceae), lupeol (1), betulonic acid (2), betulinic acid (3), terminic acid (4), ursolic acid (5), $\beta$-sitosterol (6), $\alpha$-spinasterol (7), oleanolic acid (8), 5-hydroxy-1-(4′-hydoxyphenyl)-7-(4"-hydroxyphenyl)-hepta-1-en-3-on (9), 2′-hydroxy-4′,6′-dimethoxychalcone-4-O-glucoside (10), 2′-hydroxy-4′,6′-dimethoxychalcone-4-O-[apiosyl(l$\longrightarrow$2)]glucoside (11) and syringin (12) were evaluated for their immunomodulatory properties. Compounds 6 and 11 induced the macrophage tumoricidal activity and the lymphocyte blastogenesis. In addition, these compounds stimulated the macrophages to induce the production of TNF-$\alpha$ and NO. These findings suggest that compounds 6 and 11 are modulating various elements of the host immune response.

• Food Science and Biotechnology
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• v.17 no.3
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• pp.519-526
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• 2008

To improve the quality of traditional kochujang, strains with high protease and amylase activity were isolated and identified from Sunchang traditional kochujang. Twenty-three strains strongly producing protease and 16 strains strongly producing $\alpha$- and $\beta$-amylase were isolated by using 1% isolated soy protein agar medium and 2% starch agar medium, respectively. Protease activities of the IA7, I5, and IA2 strain were 22.5, 21.2, and 20.6 unit/mL, respectively, and were higher than those of the other strains. Stains with high $\alpha$-amylase activity included K9 (967.8 unit/mL), K14 (828.3 unit/mL), K13 (662.5 unit/mL), K8 (601.5 unit/mL), and K11 (405.9 unit/mL). The $\beta$-amylase activity of the K11 strain was the highest, 34.3 unit/mL, among the isolated strains. Based on morphological, physiological properties, and API 50CHB-kit test for assimilation of 49 carbohydrates, 8 strains selected according to protease, $\alpha$-amylase, and $\beta$-amylase activities were tentatively identified as Bacillus megaterium (IA2), Bacillus subtilis (IA7, 15), Bacillus amyloliquefaciens (K8, K9, K11, and K13), and Bacillus stearothermophillus (K14). The IA7, 15, and K11 strains were finally identified as B. subtilis (99% ID) based on 16S rDNA sequencing.

• Journal of Environmental Science International
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• v.18 no.3
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• pp.325-331
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• 2009

This study was aimed to behaviour of organics and nitrogen on the upflow anaerobic reactor when a acid fermenter is added. Up flow anaerobic reactor (UAR) reaction will result which operates, COD removal efficiencies of reactor with nitrate loading rate 0.11, 0.66g/L/d were over 77%, but one with 1.0g/L/d was 73.5%. Especially, on NLR 0.11g/L/d, COD removal was 77% and nitrate removal efficiency was 93% simultaneously. The other side upflow anaerobic reactor and acid fermenter (UAR+AF) reaction will result witch operates, COD removal efficiencies of reactor with nitrate loading rate 0.11, 0.66g/L/d were over 85%, but one with 1.0g/L/d was 80%. Especially, on NLR 0.11g/L/d, COD removal was 85% and nitrate removal efficiency was 98% simultaneously. Also, without in reaction condition increase of influent nitrate concentration resulted in the linear decrease of nitrate removal efficiency and nitrate removal efficiency at influent nitrate-nitrogen 800mg/L was 50%. Alkalinity was increased theoretically by denitrification at low nitrate-N concentration, however, it was not increased theoretically at high nitrate-No 40% nitrate-N of UAR was denitrified until 70% height of reactor and 90% nitrate-N of UAR+AF was denitrified until 30% height of reactor Upflow anaerobic reactor was to occur accumulate acid, which TVA/Alkalinity is 0.3$\sim$0.47. Increase of NLR resulted increase of effluent alkalinity and TVA production

• Journal of Korean Society of Forest Science
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• v.102 no.4
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• pp.571-577
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• 2013

This study was carried out to establish the construction guidelines of soil erosion control structures for a restoration of mountain stream with analysis of water quality around constructed soil erosion control structures in mountain streams. Water pH of the Uidong valleys in Bukhansan (Mt.) was similar between the constructed soil erosion control structures of lower stream areas [pH 6.53(6.25~6.82)] and the non-constructed areas of upper stream areas [pH 6.32(5.73~6.90)]. Mean concentration of dissolved oxygen was also similar between the constructed soil erosion control structures of lower steam areas [10.2 mg/L(9.9~10.4 mg/L)] and the non-constructed areas of upper stream areas [10.3 mg/L (9.6~10.6 mg/L)]. Mean electric conductivity was similar between the lower [$63.9{\mu}S/cm$ ($32.6{\sim}120.4{\mu}S/cm$)]a nd the upper stream areas [$62.2{\mu}S/cm$ ($40.3{\sim}89.5{\mu}S/cm$)]. Mean concentration of anions was also similar between the lower [15.94 mg/L (3.43~7.98 mg/L)] and the upper stream areas [14.51 mg/L (2.56~4.29 mg/L)]. Water pH of the Honggei valleys in Sancheong-gun was similar between the lower [pH 6.86(6.50~7.10)] and the upper stream areas [pH 6.89(6.61~7.12)]. Mean concentration of dissolved oxygen was also similar between the lower [11.9 mg/L(11.5~12.3 mg/L)] and the upper stream areas [12.2 mg/L (11.6~12.6 mg/L)]. Mean electric conductivity was similar between the lower [$633.4{\mu}S/cm$ ($31.6{\sim}34.6{\mu}S/cm$)] and the upper stream areas [$32.7{\mu}S/cm$ ($31.4{\sim}34.3{\mu}S/cm$)]. Mean concentration of anion was also similar to both stream areas [1.0 mg/L (0.1~2.2 mg/L)]. Water quality in the Uidong and the Honggei valleys was not significantly different between the constructed soil erosion control structures of lower stream areas and the non-constructed areas of upper stream areas. It will be needed to study the time-series analysis of water quality before and after the construction of soil erosion control structure the restoration of mountain streams because the water quality in mountain streams could be affected during the construction processes of structures.

• Journal of Magnetics
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• v.5 no.3
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• pp.102-105
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• 2000

The extremely soft magnetic behaviors in the nanocrystalline $Fe_81B_11Nb_7Cu_1$ alloy annealed at 450 $\circ C$ and 550 $\circ C$ for 1 hour in a vacuum were investigated by means of the magnetoimpedance (MI) effect and the incremental permeability. Because the MI effect can be obtained only in ultra-soft magnetic materials, the improvement of magnetic softness by proper thermal treatment was carefully monitored by the MI effect for all annealed samples. The changes of the incremental permeability as a function of an external field were also measured to verify the magnetic softness along with the MI measurement.

• Communications for Statistical Applications and Methods
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• v.11 no.3
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• pp.643-655
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• 2004

L$_1$-estimator in the linear regression model is widely recognized to have superior robustness in the presence of vertical outliers. While the L$_1$-estimation procedures and algorithms have been developed quite well, less progress has been made with the hypothesis test in the multiple L$_1$-regression. This article suggests computer-intensive resampling approaches, jackknife and bootstrap methods, to estimating the variance of L$_1$-estimator and the scale parameter that are required to compute the test statistics. Monte Carlo simulation studies are performed to measure the power of tests in small samples. The simulation results indicate that bootstrap estimation method is the most powerful one when it is employed to the likelihood ratio test.

• The Pure and Applied Mathematics
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• v.11 no.2
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• pp.155-166
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• 2004

In this paper, we introduce new monotone concepts for set-valued mappings, called generalized C(x)-L-pseudomonotonicity and weakly C(x)-L-pseudomonotonicity. And we obtain generalized Minty-type lemma and the existence of solutions to vector variational inequality problems for weakly C(x)-L-pseudomonotone set-valued mappings, which generalizes and extends some results of Konnov & Yao [11], Yu & Yao [20], and others Chen & Yang [6], Lai & Yao [12], Lee, Kim, Lee & Cho [16] and Lin, Yang & Yao [18].

• Korean Journal of Acupuncture
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• v.24 no.4
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• pp.201-219
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• 2007

Objectives : We studied Effects of Hagocho(prunella vulgaris L.), Gamgook(chrysanthemum indicum L.) and Galgeun(pueraria Radix) aqua-acupuncture on the hyperlipidemic rat. methods : We investigated lowering lipid effect, oxidative capacity, concentration of TNF-${\alpha}$, IL-6, Leptin and histological consideration in hyperlipidemic rat. Forty male Sprague-Dawley rats weighing about 400g were divided into 5 groups of control, Ⅰ: Hagocho (prunella vulgaris L.)+Gamgook (chrysanthemum indicum L.) and Gokji aqua-acupuncture, Ⅱ: Hagocho(prunella vulgaris L.)+Gamgook (chrysanthemum indicum L.) and Joksamri aqua-acupuncture, Ⅲ: Hagocho(prunella vulgaris L.)+Galgeun(pueraria Radix)and Gokji aqua-acupuncture and Ⅳ: Hagocho (prunella vulgaris L.)+Galgeun(pueraria Radix) and Joksamri aqua-acupuncture. Results : Contents of plasma ${\beta}$-lipoprotein, contents of IL-6, TNF-${\alpha}$ and leptin, Plasma triglyceride and glucose, plasma total cholesterol and LDL-cholesterol, liver total cholesterol, liver triglyceride, plasma and liver TBARS, free fatty acids showed a tendency to decrease in the aqua-acupuncture groups compared to those of control group. The activities of GOT and GPT showed no significantly different in all treatment groups. Values of super oxide dismutase, glutathione peroxidase and catalase activity showed a tendency to increase in the aqua-acupuncture groups. Histological consideration of heart, kidney and liver in the aqua-acupuncture groups showed slight vasodilation and fat accumulation compared to those of normal rat. Conclusions : These results indicated that prunella vulgaris L., chrysanthemum indicum L. and pueraria Radix aqua-acupuncture at gokji(LI11) and Joksamri(ST36) suppressed adipose tissue mass and lipid peroxidation and increased antioxidant system in hyperlipidemic rat.

• Proceedings of the Botanical Society of Korea Conference
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• 2001.04a
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• pp.11-11
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• 2001

• Natural Product Sciences
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• v.10 no.2
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• pp.59-62
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• 2004

A novel chlorinated diterpene quinone methide; chlorosmaridione (7-chloro-11-hydroxy-abeita-7,9(11),13-triene-6,12-diode) was isolated from petroleum ether extract of the stems of Rosemarinus officinalis L. growing in Egypt. In addition, ${\beta}-sitosterol$, stigmasterol, lupeol acetate, ${\alpha}-amyrin,\;{\beta}-amyrin$, lupeol, acetyloleanolic acid, acetylursolic acid taxodione, horminone, and cryptotanshinone were also identified. Chemical structures of the isolated compounds have been elucidated on the bases of physical, chemical, and spectral data including IR, UV, MS, 1D-and 2D-NMR spectra.