• Journal of Plant Biology
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• 제29권1호
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• pp.53-65
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• 1986

The montane forests of Ulreung Island, Korea, were investigated by the ZM school method. By comparing the montane forests of this island with those of Korean Peninsula and of Japan, a new order, F a g e t a l i a m u l t i n e r v i s, a new alliance, F a l g i o n m u l t i n e r v i s, a new association, H e p a t i c o-F a g e t u m m u l t i n e r v i s and Rhododendron brachycarpum-Pinus parviflora community were recognized. The H e p a t i c o - F a g e t u m m u l t i n e r v i s was further subdivided into four subassociations; Subass. of Sasa kurilensis, Subass. of Rumohra standishii, Subass. of Rhododendron brachycarpum and Subass. of typicum. Each community was described in terms of floristic, structural and environmental features.

• Kyungpook Mathematical Journal
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• 제45권2호
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• pp.293-299
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• 2005

Let ${\cal{L}}$ be a commutative subspace lattice on a Hilbert space ${\cal{H}}$ and X and Y be operators on ${\cal{H}}$. Let $${\cal{M}}_X=\{{\sum}{\limits_{i=1}^n}E_{i}Xf_{i}:n{\in}{\mathbb{N}},f_{i}{\in}{\cal{H}}\;and\;E_{i}{\in}{\cal{L}}\}$$ and $${\cal{M}}_Y=\{{\sum}{\limits_{i=1}^n}E_{i}Yf_{i}:n{\in}{\mathbb{N}},f_{i}{\in}{\cal{H}}\;and\;E_{i}{\in}{\cal{L}}\}.$$ Then the following are equivalent. (i) There is an operator A in $Alg{\cal{L}}$ such that AX = Y, Ag = 0 for all g in ${\overline{{\cal{M}}_X}}^{\bot},A^*A=AA^*$ and every E in ${\cal{L}}$ reduces A. (ii) ${\sup}\;\{K(E, f)\;:\;n\;{\in}\;{\mathbb{N}},f_i\;{\in}\;{\cal{H}}\;and\;E_i\;{\in}\;{\cal{L}}\}\;<\;\infty,\;{\overline{{\cal{M}}_Y}}\;{\subset}\;{\overline{{\cal{M}}_X}}$and there is an operator T acting on ${\cal{H}}$ such that ${\langle}EX\;f,Tg{\rangle}={\langle}EY\;f,Xg{\rangle}$ and ${\langle}ET\;f,Tg{\rangle}={\langle}EY\;f,Yg{\rangle}$ for all f, g in ${\cal{H}}$ and E in ${\cal{L}}$, where $K(E,\;f)\;=\;{\parallel}{\sum{\array}{n\\i=1}}\;E_{i}Y\;f_{i}{\parallel}/{\parallel}{\sum{\array}{n\\i=1}}\;E_{i}Xf_{i}{\parallel}$.

• 한국응용과학기술학회지
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• 제37권6호
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• pp.1545-1555
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• 2020

In the present study, we investigated the antioxidant activity of Aucklandia lappa Decne (AL). Cell viability was measured in an MTT assay. Antioxidant effects were evaluated based on total polyphenol/flavonoid contents, ABTS radical scavenging activity, DPPH radical scavenging activity, SOD activity, and ROS content. AL was found not to be toxic at concentrations of 1 ㎍/mL, 10 ㎍/mL, and 100 ㎍/mL, respectively. The phenolic content was higher in AL-D than in AL-E, while the flavonoid content was higher in AL-E than in AL-D. AL-E exhibited higher ABTS radical scavenging activity than AL-D, and the EC50 values for BHA were 217.1 ㎍/mL in AL-D and 180.5 ㎍/mL in AL-E. AL-E also showed the highest DPPH radical scavenging activity. EC50 values for BHA were 114.2 ㎍/mL in AL-D and 95.8 ㎍/mL in AL-E. The SOD-like activity of AL-E was higher than that of AL-D. The EC50 values for ascorbic acid were 48.5 ㎍/mL in AL-D and 72.9 ㎍/mL in AL-E, indicating that both AL extracts have a SOD activity higher than that of ascorbic acid. AL-E reduced relatively more ROS than AL-D. With 100 ㎍/mL AL-E, the reduction level was almost similar to that of dexamethasone. Our results demonstrate that AL have antioxidant effects, and we believe that they could be very valuable as raw materials for anti-aging products, based on their antioxidant activity.

• Journal of Applied Biological Chemistry
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• 제66권
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• pp.424-435
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• 2023

본 연구 결과 DPPH 라디칼 소거 활성은 갈랑가 뿌리 70% 에탄올 추출물(AG.E) 100 ㎍/mL 농도에서 81.8%이었으며 ABTS⁺ 라디칼 소거 활성은 AG.E 50 ㎍/mL의 낮은 농도에서 L-Ascorbic acid (AA)와 유사한 99.8%로 확인되었다. 항노화 활성을 측정하기 위하여 collagenase와 elastase 저해 활성을 측정한 결과 둘 모두에서 AG.E는 50 ㎍/mL의 낮은 농도부터 epigallocatechin (EGCG)보다 더 높은 저해 효과를 나타내었다. 특히 500 ㎍/mL 농도에서 EGCG 대비 3배 이상의 저해 효과를 보였다. CCD-986sk 세포내에서 AG.E의 항노화 효과를 검증하기 위해 UVB로 자극한 다양한 실험에서도 우수한 항노화 효과가 얻어졌다. RT-PCR을 통한 유전자 발현 분석 실험에서 COL1A mRNA 발현량은 AG.E 20 ㎍/mL 저농도에서 무첨가 대비 2.90배 증가시키는 결과가 얻어져 항노화관련 우수한 기능성 소재로 개발 가능성이 확인되었다. 제형에 소재의 적용 시 생리활성의 경시적 보전성에 대한 기초 연구로서 AG.E 및 AA등을 안정한 W/O type emulsion에 첨가하여 25 ℃ 항온조에 보관하면서 1일차, 30일차, 60일차에 DPPH와 ABTS+ 라디칼소거 활성을 측정한 결과 모두 경시적으로 항산화 효과가 높은수준 유지됨을 확인하였다.

• Genomics & Informatics
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• 제21권3호
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• pp.32.1-32.11
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• 2023

Resistance to anti-tuberculosis drugs, especially ethambutol (EMB), has been widely reported worldwide. EMB resistance is caused by mutations in the embB gene, which encodes the arabinosyl transferase enzyme. This study aimed to detect mutations in the embB gene of Mycobacterium tuberculosis from Papua and to evaluate their impact on the effectiveness of EMB. We analyzed 20 samples of M. tuberculosis culture that had undergone whole-genome sequencing, of which 19 samples were of sufficient quality for further bioinformatics analysis. Mutation analysis was performed using TBProfiler, which identified M306L, M306V, D1024N, and E378A mutations. In sample TB035, the M306L mutation was present along with E378A. The binding affinity of EMB to arabinosyl transferase was calculated using AutoDock Vina. The molecular docking results revealed that all mutants demonstrated an increased binding affinity to EMB compared to the native protein (-0.948 kcal/mol). The presence of the M306L mutation, when coexisting with E378A, resulted in a slight increase in binding affinity compared to the M306L mutation alone. The molecular dynamics simulation results indicated that the M306L, M306L + E378A, M306V, and E378A mutants decreased protein stability. Conversely, the D1024N mutant exhibited stability comparable to the native protein. In conclusion, this study suggests that the M306L, M306L + E378A, M306V, and E378A mutations may contribute to EMB resistance, while the D1024N mutation may be consistent with continued susceptibility to EMB.

• 응용통계연구
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• 제1권1호
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• pp.39-44
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• 1987

다변량 정규모집단에서 공분산행렬의 m.l.e.를 유도하기 위하여 m.l.e.의 불변성에 기초를 둔 Anderson의 방법은 그 절차의 단순성이라는 측면에서 일반적으로 선호되고 있다. 본고는 공통요인분석모형이나 Simplex 구조모형과 같은 다변량구조모형에서 이 접근방법을 적용하여 요구되는 m.l.e.를 구하는 과정을 보이고 있다.

• Journal of applied mathematics & informatics
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• 제15권1_2호
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• pp.503-510
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• 2004

Given vectors x and y in a Hilbert space, an interpolating operator is a bounded operator T such that Tx = y. An interpolating operator for n vectors satisfies the equation $Tx_i\;=\;y_i,\;for\;i\;=\;1,\;2,\;\cdots,\;n$. In this paper the following is proved: Let H be a Hilbert space and L be a commutative subspace lattice on H. Let H and y be vectors in H. Let $M_x\;=\;\{{\sum{n}{i=1}}\;{\alpha}_iE_ix\;:\;n\;{\in}\;N,\;{\alpha}_i\;{\in}\;{\mathbb{C}}\;and\;E_i\;{\in}\;L\}\;and\;M_y\;=\;\{{\sum{n}{i=1}}\;{\alpha}_iE_iy\;:\;n\;{\in}\;N,\;{\alpha}_i\;{\in}\;{\mathbb{C}}\;and\;E_i\;{\in}\;L\}. Then the following are equivalent. (1) There exists an operator A in AlgL such that Ax = y, Af = 0 for all f in ${\overline{M_x}}^{\bot}$, AE = EA for all $E\;{\in}\;L\;and\;A^{*}\;=\;A$. (2) $sup\;\{\frac{{\parallel}{{\Sigma}_{i=1}}^{n}\;{\alpha}_iE_iy{\parallel}}{{\parallel}{{\Sigma}_{i=1}}^{n}\;{\alpha}_iE_iy{\parallel}}\;:\;n\;{\in}\;N,\;{\alpha}_i\;{\in}\;{\mathbb{C}}\;and\;E_i\;{\in}\;L\}\;<\;{\infty},\;{\overline{M_u}}\;{\subset}{\overline{M_x}}$ and < Ex, y >=< Ey, x > for all E in L.

• 한국식품위생안전성학회지
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• 제19권3호
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• pp.151-160
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• 2004

우리나라 고유의 전통발효 식품인 메주로부터 항리스테리아 활성을 나타내는 유산균을 분리한 후 동정한 결과 E. faecium MJ5-14로 명명되었으며, 이들의 박테리오신은 MRS broth 중에 $37^{\circ}C$에서 12-18시간 배양하는 동안 최대의 활성을 나타내었다. L. monocytogenes KCTC 3569와 KCTC 3710 및 L. ivanovii subsp. ivanovii에 대한 박테리오신의 활성은 640 BU/mL이었고, L. innocua ATCC 33090, L. ivanovii ATCC 19119, L. grayi KCTC 3581 및 L. seeliger KCTC 3591에 대한 활성은 1280 BU/mL으로 나타났다. L. monovytogenes KCTC 3569와 E. faecium MJ5-14을 혼합 배양한 경우 L. monocytogenes의 감소 효과는 $25^{\circ}C$이하 보다는 E. faecium MJ5-14의 박테리오신 생산 최적 온도인 $37^{\circ}C$에서 더 높게 나타났으며, E. faecium MJ15-14의 박테리오신 항균 효과는 L. monocytogenes KCTC 3569의 초기 균수와 첨가한 박테리오신의 양에 따라 좌우하는 L. monocytogenes의 초기 균수가 적고, 박테리오신의 첨가량이 많을수록 항균효과가 높아짐을 확인하였다. 또한 박테리오신 70 BU/mL 첨가에 의한 항균 효과는 균 증식이 활발한 대수증식기 중반 이후 보다는 유도기 내지는 대수증식기 초반부에 더 크게 나타났다. 한편, 박테리오신 25 BU/mL을 첨가에 의해서 L. monocytogenes KCTC 3569 새포벽의 일부가 얇아지고, 50 BU/mL 이상의 농도에 의해선 세포막이 파괴되면서 세포 내용물의 유출 현상이 관찰되었다.

• Journal of applied mathematics & informatics
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• 제38권5_6호
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• pp.591-600
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• 2020

This work is a continuation of our investigations for p-adic analogue of the alternating form Dirichlet L-functions $$L_E(s,{\chi})={\sum\limits_{n=1}^{\infty}}{\frac{(-1)^n{\chi}(n)}{n^s}},\;Re(s)>0$$. Let L_p,E(s, t; χ) be the p-adic Euler L-function of two variables. In this paper, for any α ∈ ℂ_p, |α|_p ≤ 1, we give a power series expansion of L_p,E(s, t; χ) in terms of the variable t. From this, we derive a power series expansion of the generalized Euler polynomials with negative index, that is, we prove that $$E_{-n,{\chi}}(t)={\sum\limits_{m=0}^{\infty}}\(\array{-n\\m}\)E_{-(m+n),{\chi}^{t^m}},\;n{\in}{\mathbb{N}}$$, where t ∈ ℂ_p with |t|_p < 1. Some further properties for L_p,E(s, t; χ) has also been shown.

• 대한기계학회논문집
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• 제19권1호
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• pp.87-98
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• 1995

When the crack in orthotropic material is propagating under dynamic model I load, influences of anisotropic property ratio $E_{L}$/ $E_{T}$ on stress and displacement around propagating crack tip are studied in this paper. When M<0.55 and .alpha.=90.deg.(.alpha.; the angle of fiber direction with crack propagating direction, M; crack propagation velocity/shear stress wave velocity), the influence of $E_{L}$/ $E_{T}$ on stress .sigma.$_{x}$, .sigma.$_{y}$, .tau.$_{xy}$ and .sigma.$_{\theta}$ is the greast on .sigma.$_{y}$. Except M<0.55 and .alpha.=90.deg., it is the greast on .sigma.$_{x}$ in any situation. Increasing $E_{L}$/ $E_{T}$, stress components are increased or decreased. When maximum stress is based, the stress .sigma.$_{x}$(.alpha.=90.deg.), .sigma.$_{y}$(.alpha.=0.deg.) and .tau.$_{xy}$ (.alpha.=90.deg.) are decreased with increment of $E_{L}$/ $E_{T}$ in M=0. any stresses except .sigma.$_{*}$x/(.alpha.=0.deg.) are decreased with increment of $E_{L}$/ $E_{T}$ in M=0.9. When .alpha.=90.deg., the influence of $E_{L}$/ $E_{T}$ on displacement U and V is V>U in any velocities of crack propagation, when .alpha.=0.deg., it is VU in M>0.75 and when $E_{L}$/ $E_{T}$ is increased, U and V are decreased in any conditions.sed in any conditions.tions.tions.tions.