• Title/Summary/Keyword: L-His

Search Result 422, Processing Time 0.027 seconds

On Euler : His Life and Mathematics, and Euler Archive (오일러가 수학사에 미친 영향에 대한 소고 오일러의 탄생 300주년을 기념하며)

  • Koh, Young-Mee;Ree, Sang-Wook
    • Journal for History of Mathematics
    • /
    • v.20 no.3
    • /
    • pp.27-42
    • /
    • 2007
  • Many countries in the world are celebrating the tercentenary of the birth of L. Euler. One of them to notice is the construction of the Euler Archive, which is an online archive, made by two Ph.D. graduates from Dartmouth College. On the appearance of the archive, the authors remind of the life and works of mathematician L. Euler, who is considered as the most prolific, prominent, and versatile mathematician with the huge volume of his works as well as their importances, in the history of mathematics. Celebrating the 300th birthyear of L. Euler and the appearance of Euler Archive, authors suggest The Korean Society for History of Mathematics of investigating on Euler by ourselves as Koreans, and furthermore translating some works of his. Such works may stimulate interests in mathematics and its history to students as well as scholars.

  • PDF

Reexamination on Foreign Collectors' Sites and Exploration Routes in Korea (III) - with respect to T. Uchiyama - (외국인의 한반도 식물 채집행적과 지명 재고(III): Tomijiro Uchiyama)

  • Kim, Hui;Choi, Byoung-Hee;Chang, Chin-Sung;Chang, Kae-Sun
    • Korean Journal of Plant Taxonomy
    • /
    • v.37 no.2
    • /
    • pp.203-215
    • /
    • 2007
  • Uchiyama, Tomijiro visited the Korean peninsula including Busan, Incheon, Nampo, Pyongyang, Seoul, Mt. Geumgang of Gangwon-do, and Jeju-do twice for his plant collections in 1900 and 1902, respectively. During his plant explorations, Uchiyama collected numerous specimens which were investigated and studied by T. Nakai (Flora Koreana I and II and other publications) and H. $L{\acute{e}}veill{\acute{e}}$ later. Unfortunately all collection sites were simply described by Nakai in Romanized characters, so that it is difficult to pinpoint those sites using the current or the old Korean map. From this study, many locality names were reviewed based on his own plant specimens at TI and literatures, and those were listed as the order of his collection dates. Based on specimens deposited at TI, only ca. 200 specimens were confirmed, although 1,674 specimens were listed by Nakai. Among his collections, 2/3 of his collections were conducted in 1902 and among them 41 specimens were cited as type collections by Nakai.

Gregor Mendel and the Seven Genes (1)

  • Tateno, Yoshio
    • Interdisciplinary Bio Central
    • /
    • v.5 no.4
    • /
    • pp.7.1-7.3
    • /
    • 2013
  • This essay describes G. Mendel's life and his law of inheritance. He was born in a poor family in 1822 in a hamlet in Czechs. At that time the Habsburg Empire dominated over the East Europe in which Vienna was the capital. Vienna had thus been the center of culture and learning, and attracted many artists and scholars such as W. Mozart (1756- 1791), L. Beethoven (1770-1827), C. Doppler (1803-1853), S. Freud (1856-1939), G. Mahler (1860-1911), G. Klimt (1862-1918) and E. Schiele (1890-1918). Beethoven came to Vienna to learn from Mozart. Klimt was influence by Schilele. When Mahler consulted Freud about his mental problem, Freud said to him "Your mental condition was not normal, but the condition made you creative. So, do not worry too much about it." Like that, there were many interactions among them, and Mendel was no exception. Though Mendel was poor, he was fortunate in his education and scientific research, because he could have excellent supporters in his family and out of it. He learned mathematics and physics at Vienna University under the guidance of C. Doppler. He was not totally alone when he discovered his law of inheritance. It may not be true either that his law was neglected and rediscovered in the year of 1900. As his one and only paper indicates, he was one of the earliest interdisciplinary scientists.

Interdisciplinary and philosophy of Diderot Considered through De l'interprétation de la nature ('융·복합'과 디드로의 철학 - 『자연해석론』을 중심으로 -)

  • PAEK, Chan-Wook
    • Cross-Cultural Studies
    • /
    • v.33
    • /
    • pp.143-169
    • /
    • 2013
  • Recently, because of the danger and damages that following the steady development of scientific technologies, natural science is faced with many humane and ethical problems. So it is asserted the interdisciplinary with social and human science. However, it comes commonly that the ethical issues such as world view and one's view of life caused the development of sociology, especially development of the market economy. But in many cases, the interdisciplinary can be useful for widen the view of scholars. The interdisciplinary is actually connected with the problems of philosophy, and located in that domain. In this case, this is noticed as a model to the philosophers in 18th century, especially Denis Diderot. Diderot published De $l^{\prime}interpr{\acute{e}}tation$ de la nature during editing the Encyclopedia, from there he picked out the contents from piles of documents of Encyclopedia. Even though the contents or opinions of De $l^{\prime}interpr{\acute{e}}tation$ de la nature are inaccuracy or erroneous, it shows that how human-social science and natural science encountered. Diderot studied mathematics and then Diderot accepted to the natural science proposal, he approaches philosophy with translate English books to the French. Next he understood natural science by reading Buffon and Maupertuis, and during working for Encyclopedia, he possessed his knowledge that he can claim his opinion to other scholars. However in this De $l^{\prime}interpr{\acute{e}}tation$ de la nature, Diderot who sometimes rebutted other scholars' theory and demonstration, tried to build a philosophy on metaphysics in order to it was important for himself that he imposed the methods of science and importance of experience. Anyhow, this De $l^{\prime}interpr{\acute{e}}tation$ de la nature cause consider the recognition of Diderot in the field of natural science, and is suggested as a model about his Nature. This mean that it is an expression of his philosophy, and the content is found from natural philosophy and empirical philosophy. Like giving these attache the importance of method study for science and technique, these are targeted the promotion of popularization of natural-science and scientific-technology. Also it advocates fulfilling from reasonable philosophy to empirical philosophy. Therefore, the philosophy which was speculative and abstracted became his philosophy which was writing the meaning, as waiting the discovery of science. And at that time, the humanities made interdisciplinary with natural science.

Characterization of Surface Layer Proteins in Lactobacillus crispatus Isolate ZJ001

  • Chen, Xueyan;Chen, Yang;Li, Xiaoliang;Chen, Ning;Fang, Weihuan
    • Journal of Microbiology and Biotechnology
    • /
    • v.19 no.10
    • /
    • pp.1176-1183
    • /
    • 2009
  • Lactobacillus crispatus (L. crispatus) ZJ001 is highly adhesive to epithelial cells and expresses S-layer proteins. In this study, S-S-layer layer genes were sequenced and expressed in E. coli to characterize the function of proteins with this particular strain. L. crispatus ZJ001 harbored two S-layer genes slpA and slpB, and only slpA gene was expressed in the bacterium, as revealed by RT-PCR and immunoassays. The mature SlpA showed 47% amino acid sequence identity to SlpB. The SlpA and SlpB of L. crispatus ZJ001 were highly homologous at the C-terminal region to other Lactobacillus S-layer proteins, but were substantially variable at N-terminal and middle regions. Electron microscopic analysis indicated that His-slpA expressed in E. coli was able to form a sheet-like structure similar to the natural S-layer, but His-slpB formed as disc-like structures. In the cell binding experiments, HeLa cells were able to bind to both recombinant His-slpA and His-slpB proteins to the extent similar to the natural S-layer. The cell binding domains remain mostly in the N-terminal regions in SlpA and SlpB, as shown by high binding of truncated peptides SlpA2-228 and SlpB2-249. Our results indicated that SlpA was active and high binding to HeLa cells, and that the slpA gene could be targeted to display foreign proteins on the bacterial surface of ZJ001 as a potential mucosal vaccine vector.

Enhancement of Cyclo-His-Pro (CHP) Content from Soybean Fermented with Bacillus amyloliquefaciens CHP-12 and Its Anti-diabetic Effect (Bacillus amyloliquefaciens CHP-12에 의한 대두 발효물의 Cyclo-His-Pro (CHP) 함량 증진 및 항당뇨 효과)

  • Ra, Kyung-Soo;Choi, Jang-Won
    • KSBB Journal
    • /
    • v.26 no.1
    • /
    • pp.41-48
    • /
    • 2011
  • To enhance cyclo-His-Pro (CHP) content, soybean hydrolysate was obtained using the strains isolated from Chungkukjang and further purified by various purification steps. First, twenty two strains were screened from Chungkukjang containing high level of CHP. Among them, the strain No. 12, which showed higher productivity of CHP from soybean ferment and have homologous sequence with 16S rDNA of Bacillus amyloliquefaciens, was named B. amyloliquefaciens CHP-12. Through various purification processes, CHP was concentrated from soybean ferment using ultrafiltration, which showed the best efficiency of CHP production, with the yield (71.3%) and CHP content (2.14 mg/g). Moreover, when glucose tolerance test was performed in Type I Sprague-Dawley rat induced by streptozotocin using the soybean ferments [0.5 g soybean ferment/kg body weight (CHP-0.5 group)] and 1.0 g soybean ferment/kg body weight (CHP-1.0 group), there were significant differences in glucose levels between diabetes-control group (265.3 mg/dL) and soybean ferment-treated groups (CHP-0.5 group: 84.3 mg/dL and CHP-1.0 group: 85.3 mg/dL) 120 min after glucose injection (2 g/kg body weight) (p < 0.05). Accordingly, it is suggested that the soybean ferment containing high level of CHP might be a candidate material as an anti-diabetic supplement for manufacturing functional healthy foods.

A Study on the Remedial Cases of Anticipatory Breach in int'l Sales (국제물품매매에서 이행기전 계약위반에 대한 구제권 연구(사례를 중심으로))

  • Ha, Kang-Hun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
    • /
    • v.39
    • /
    • pp.3-26
    • /
    • 2008
  • CISG provides the Convention's default provisions on anticipatory breach. Article 71 permits the aggrieved party to suspend the performance of his obligations if it becomes apparent that the other party will not perform a substantial part of his obligations after the conclusion of the contract. The aggrieved party must give notice of the suspension to the other party and if he provides adequate assurance of his performance, the party must continue with performance. Article 72 authorizes the aggrieved party to avoid the contract to the date of performance when it is clear that the other party will commit a fundamental breach. The aggrieved party is also required to give the other party notice of his intent to avoid the contract if time allows. The requirements for avoidance under Article 72 are more stringent than those for suspension under Article 71. Article 72 requires reasonable prior notice only if time allows, while article 71 requires immediate notice with no exceptions.

  • PDF

Early Onset Renal Failure in Congenital Nephrotic Syndrome associated with Congenital Diaphragmatic Hernia by WT1 Gene Mutation (WT1 유전자 돌연변이에 의해 선천성 가로막 탈장이 동반되고 조기 신부전이 초래된 선천성 신증후군 1례)

  • Park, Yong-Jun;Oh, Jin-Won;Choi, Kyong-Min;Kim, Pyung-Kil;Lee, Jong-In;Song, Ji-Sun
    • Childhood Kidney Diseases
    • /
    • v.13 no.1
    • /
    • pp.84-91
    • /
    • 2009
  • We experienced a female neonate with congenital nephrotic syndrome (CNS) associated with congenital diaphragmatic hernia (CDH). Because of the rare combination of two conditions, we report this case with literature review. CDH was found immediately after birth and emergency operation was done for hernia repair. But on the next day, generalized edema and oliguria(0.59 mL/kg/hour) was found and her blood chemistry showed hypoalbuminemia (1.6 g/dL), increased BUN (27.7 mg/dL) and serum creatinine( 1.8 mg/dL) along with heavy proteinuria (4+). We started albumin infusion with a bolus of intravenous furosemide. We suspected the neonate had congenital nephrotic syndrome and her 24hr urine protein was 1,816 mg/day. In spite of immunosuppressive therapy, the nephrotic syndrome and renal failure progressed. We started peritoneal dialysis on the day of life 22 but it was not satisfactory. She was complicated by intracranial hemorrhage and multi-organ failure and expired at 34 days of age. Kidney necropsy was performed which showed diffuse mesangial sclerosis (DMS). Her chromosome study revealed 46, XX and her gene study revealed a heterozygous missense mutation, Arg366His, in Wilms tumor suppressor gene (WT1). This case deserves attention on account of the 4th case of CNS with CDH revealing the Arg366His mutation in the WT1 gene and G the 1st case of early onset renal failure without male pseudohermaphroditism and Wilms tumor with CNS, CDH and the Arg366His mutation in the WT1 gene. So, this report gives support to the hypothesis that Arg366His mutation in the WT1 gene can result in CNS and CDH.

Preparation for Protein Separation of an Ion-Exchange Polymeric Stationary Phase Presenting Amino Acid and Amine Units Through Surface Graft Polymerization

  • Choi Seong-Ho;Lee Kwang-Pill;Shin Chang-Ho
    • Macromolecular Research
    • /
    • v.13 no.1
    • /
    • pp.39-44
    • /
    • 2005
  • Ion-exchange polymeric stationary phases presenting amino acid and amino groups were prepared by the surface grafting of glycidyl methacrylate onto a silica gel surface and subsequent amination. Three kinds of amino acids-L-arginine (Arg), D-lysine (Lys), and D-histine (His)-were used in this study. An ion-exchange polymeric stationary phase presenting ethylene diamine (EDA) was also prepared by surface graft polymerization. Separation of the model proteins bovine serum albumin (BSA), chick egg albumin (CEA), and hemoglobin (Hb) was performed using the amino acid- and amine-derived columns. In separating the CEA/BSA mixture, the resolution time of BSA was longer than that of CEA when using the EDA column, whereas the resolution time of BSA was shorter than that of CEA when using the Arg, Lys, and His columns. In the separation of the Hb/BSA mixture, the resolution time of BSA was longer than that of Hb in the EDA column, whereas the resolution time of BSA was shorter than that of Hb in the amino acid columns (D-Lys, L-Arg, and D-His).

Sudden Intraoperative Hyperkalemia during Laparoscopic Radical Nephrectomy in a Patient with Underlying Renal Insufficiency

  • Jung, Sung Hoon;Han, Yun-Joung;Shin, Sang Ho;Lee, Hyo Seon;Lee, Ji Young
    • Acute and Critical Care
    • /
    • v.33 no.4
    • /
    • pp.271-275
    • /
    • 2018
  • We experienced a case of severe intraoperative hyperkalemia during laparoscopic radical nephrectomy in a 60-year-old male patient with renal insufficiency, whose hypertension had been managed by preoperative angiotensin II receptor blocker (ARB) and adrenergic beta-antagonist. After renal vessel ligation, his intraoperative potassium concentration suddenly increased to 7.0 mEq/L, but his electrocardiography (ECG) did not show any significant change. While preoperative ARB therapy has been regarded as a contributing factor for further aggravation of underlying renal insufficiency, we assumed that nephrectomy itself and rhabdomyolysis caused by surgical trauma also aggravated the underlying renal dysfunction and resulted in sudden hyperkalemia. Hyperkalemia was managed successfully with calcium gluconate, insulin, furosemide and crystalloid loading during the intraoperative and immediate postoperative periods, and potassium concentration decreased to 5.0 mEq/L at 8 hours after the operation. The patient's hospital course was uncomplicated, but his renal function deteriorated further.