• Title/Summary/Keyword: Kwan Soo Lee

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Current Status and Perspective of Biological Assessments of Water Environment in Korea (우리나라 생물학적 물환경평가의 현황과 미래)

  • Hwang, Soon-Jin;Kim, Nan-Young;Won, Doo Hee;An, Kwang Kuk;Lee, Jae Kwan;Kim, Chang Soo;Shin, Jae-Ki
    • Journal of Korean Society on Water Environment
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    • v.22 no.5
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    • pp.757-767
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    • 2006
  • Biological assessments are the primary tool for evaluating the biological condition of a water body and makes it possible to understand accumulative and long-term effect of stressors. They also provide reliable biological information for which disturbed systems are to be restored. Sustainable water environment is not enough with attaining only the clean water, but it should sustain healthy and diverse aquatic life. Aquatic organisms are affected by various factors, including not only water quality but also habitat condition and stressors, and thus good condition of both physical and chemical water quality is prerequisite for sustaining healthy organisms. Therefore, biological assessment, along with other physical and chemical assessments, are crucial for evaluating the health of a water body. Overall, sustainability of water environment demands the attainment and maintenance of ecological integrity, which is resulted from the combination of physical, chemical and biological integrity. The biological criteria will play very important role in the water resource management and policy issues, and thus bioassessment program should be fully implemented and supported eventually by the law. To keep ecosystem health of water environment safely from the toxic pollutants and other stressors, the following suggestions need to be considered in environmental quality standards in Korea. For the first step, the biological indicators need to be introduced in evaluating river quality condition; they provide a qualitative description of biological condition of water body. Secondly, the biological water quality standards using biotic indices should be developed and implemented under the consideration of characteristics of Korean river systems. Lastly, the ecological status classification regime (ESCR) should be developed and introduced; it could be used in quality assessment of the water environment in general. In developing ESCR, integration of physico-chemical, biological, and habitat parameters should be taken into account.

Left Atrial Myxoma Associated with Mitral Regurgitation and Coronary Artery Disease (승모판막폐쇄부전 및 관상동맥질환과 동반된 좌심방 점액종)

  • Baek, Man-Jong;Na, Chan-Young;Oh, Sam-Sae;Kim, Woong-Han;Whang, Sung-Wook;Lee, Cheol;Chang, Yun-Hee;Jo, Won-Min;Kim, Jae-Hyun;Seo, Hong-Ju;Park, Yoon-Ock;Moon, Hyun-Soo;Paik, Young-Kwan;Kim, Chong-Whan
    • Journal of Chest Surgery
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    • v.36 no.11
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    • pp.862-865
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    • 2003
  • Obstructive intracardiac lesions, like mitral stenosis or insufficiency (MR), by myxomas of the left atrium have been commonly reported, but the attenuation of MR by myxoma combined with coronary artery disease is very rare. We report a 70-year-old female patient whose left atrial myxoma had attenuated moderate MR to mild MR and required mitral valve surgery after removal of the myxoma. She also had coronary artery disease, severe pulmonary hypertension and moderate tricuspid regurgitation due to the mitral valve lesions obstructed by myxoma. The patient underwent removal of myxoma, mitral and tricuspid valve reconstructions, and coronary artery bypass grafting. She was discharged at the postoperative 14 day without any problems.

Analysis of Left Ventricular Functional Parameters in Normal Korean Subjects by ECG Gated Blood Pool Scan (정상 한국인에서 게이트혈액풀스캔을 이용한 좌심실 심기능지표들의 분석)

  • Kang, Jae-Hwang;Park, Une-Sook;Kang, Byeong-Sun;Lim, Hyeon-Ok;Choi, Dong-Soo;Suh, Bong-Kwan;Chung, Soon-Il;Lee, Keun-Woo
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.1
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    • pp.52-61
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    • 1994
  • Background : The demand for refinement in noninvasive and quantitative assessment of left ventricular (LV) function is increasing. Purpose : To assess normal values of left ventricular functional parameters during both systole and diastole by scintigraphic method using computerized triple-head gamma camera and to evaluate correlations between these parameters. Methods : ECG gated blood pool scan with $^{99m}Tc$-Human serum albumin was performed in 94 normal Korean subjects. Ejection fraction (EF), systolic parameters [peak emptying rate (PER), average emptying rate (AER), time to peak emptying rate (TPER)], and diastolic parameters [peak filling rate (PFR), average filling rate (AFR), time to peak filling rate (TPFR)] were obtained by analysis of LV time-activity curve, the correlation of these parameters to the age and sex, and the correlation between these parameters were evaluated. Results : 1) Mean value of ejection fraction in study subjects was $59.6{\pm}5.25%$ and showed no significant correlation to age (r=-0.08) and sex but showed most pronounced correlation to PFR (r=0.46, p<0.001), PER (r=0.41, p<0.001), AFR (r=0.34, p<0.001) and AER (r=0.28, p<0.01). 2) Mean values of systolic parameters were as follows: $PER=3.22{\pm}0.50$ end-diastolic volume/sec, $AER=2.22{\pm}0.45$ end-diastolic volume/sec, $TPER=103.5{\pm}29.30$ msec. They showed no significant correlation to age and sex. 3) Mean values of diastolic parameters were as follows: $PFR=2.71{\pm}0.51$ end-diastolic volume/sec, $AFR=1.83{\pm}0.44$ end-diastolic volume/sec, $TPFR=132.1{\pm}33.45$ msec. They showed strong correlation to age (r=0.70, -0.64, 0.37, p<0.001). Conclusions : Left ventricular functional parameters in normal Korean subjects were obtained reliably by computerized scintigraphic method and may be applied to the evaluation of cardiac function in diseased patients.

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Clean Room Structure, Air Conditioning and Contamination Control Systems in the Semiconductor Fabrication Process (반도체 웨이퍼 제조공정 클린룸 구조, 공기조화 및 오염제어시스템)

  • Choi, Kwang-Min;Lee, Ji-Eun;Cho, Kwi-Young;Kim, Kwan-Sick;Cho, Soo-Hun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.25 no.2
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    • pp.202-210
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    • 2015
  • Objectives: The purpose of this study was to examine clean room(C/R) structure, air conditioning and contamination control systems and to provide basic information for identifying a correlation between the semiconductor work environment and workers' disease. Methods: This study was conducted at 200 mm and 300 mm semiconductor wafer fabrication facilities. The C/R structure and air conditioning method were investigated using basic engineering data from documentation for C/R construction. Furthermore, contamination parameters such as airborne particles, temperature, humidity, acids, ammonia, organic compounds, and vibration in the C/R were based on the International Technology Roadmap for Semiconductors(ITRS). The properties of contamination control systems and the current status of monitoring of various contaminants in the C/R were investigated. Results: 200 mm and 300 mm wafer fabrication facilities were divided into fab(C/R) and sub fab(Plenum), and fab, clean sub fab and facility sub fab, respectively. Fresh air(FA) is supplied in the plenum or clean sub fab by the outdoor air handling unit system which purifies outdoor air. FA supply or contaminated indoor air ventilation rates in the 200 mm and 300 mm wafer fabrication facilities are approximately 10-25%. Furthermore, semiconductor clean rooms strictly controlled airborne particles(${\leq}1,000{\sharp}/ft^3$), temperature($23{\pm}0.5^{\circ}C$), humidity($45{\pm}5%$), air velocity(0.4 m/s), air change(60-80 cycles/hr), vibration(${\leq}1cm/s^2$), and differential pressure(atmospheric pressure$+1.0-2.5mmH_2O$) through air handling and contamination control systems. In addition, acids, alkali and ozone are managed at less than internal criteria by chemical filters. Conclusions: Semiconductor clean rooms can be a pleasant environment for workers as well as semiconductor devices. However, based on the precautionary principle, it may be necessary to continuously improve semiconductor processes and the work environment.

Physicochemical Properties of Endosperm Starch and Breadmaking Quality of Rice Cultivars (쌀 품종의 배유 이화학적 특성에 따른 제빵 적성 비교)

  • Yoon, Mi-Ra;Chun, A-Reum;Oh, Sea-Kwan;Ko, Sang-Hoon;Kim, Dae-Jung;Hong, Ha-Cheol;Choi, Im-Soo;Lee, Jeong-Heui
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.56 no.3
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    • pp.219-225
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    • 2011
  • The physicochemical properties of rice endosperm from five rice varieties and effects of milling on baking bread properties of rice flour were investigated. Five rice varieties exhibited different level of amylose content. The ratio of longer amylopectin chain length to the distribution of endosperm starches was the highest in Goami3. According to the RVA measurement of rice flours, the pasting temperatures of Seolgaengbyeo and Goamibyeo were lower than those of the other rice varieties. There were differences in the changes of swelling power of rice flour under increasing temperature. Each rice flour sample for bread-making was processed into two different particle size by using an air-classification mill, and significant differences were observed among cultivars in the average particle size and damaged starch content of rice flours. Rice flour of Seolgaengbyeo with fine particle size showed the highest value in specific volume after baking.

Analyzing the Effect of Climatic Variables on Growth and Yield of Rice in Chuncheon Region (춘천지역의 기상요소가 벼 생육과 수량에 미치는 영향 해석)

  • Lee, An-Soo;Kim, Jae-Rok;Cho, Youn-Sang;Kim, Yong-Bog;Ham, Jin-Kwan;Jeong, Jeong-Su;Sa, Jong-Gu;Shin, Jin-Chul
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.56 no.2
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    • pp.99-106
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    • 2011
  • Here we reported an analyzing result for the relationship between climatic variables and rice(c.v. Odaebyeo and Ilpumbyeo) yield characteristics (including some growth characteristics) based on a long-term observed data at GARES and at KMA for rice and weather, respectively. Most of crop parameters investigated, such as heading date, culm height, panicle number $m^{-2}$, grain number $panicle^{-1}$ ripening rate, 1,000 grain weight and yield were strongly affected by wind velocity and relative humidity, as well as by daily mean air temperature, precipitation, sunshine hours and daily variations in air temperature depending on variety and crop developmental stages. Air velocity and relative humidity had not been studied as climatic variables affecting on the characteristics of rice growth and yield, however, they turned out to affect all the characteristics of rice investigated, especially ripening rate and yield, as much as any other climatic variables in this study. Air velocity appeared to affect highly the culm height and yield of Odaebyeo and ilpumbyeo. Relative humidity appeared to affect highly grain number and ripening rate of Odaebyeo and yield of Ilpumbyeo. Consequently Rice yield revealed to increase in the climatic conditions of high air velocity and low relative humidity.

Solubilization of Whole Grains by Extrusion and Enzyme Treatment (전곡립의 압출성형 및 효소처리에 의한 수용화)

  • Shin, Hae-Hun;Lee, Sun-Hee;Park, Bo-Sun;Rhim, Tae-Soo;Hwang, Jae-Kwan
    • Korean Journal of Food Science and Technology
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    • v.35 no.5
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    • pp.849-855
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    • 2003
  • The extrusion effects on solubilization of brown rice, glutinous rice, barley and job's tear were investigated in comparison with raw and roasted whole grains. Whole grains were extruded under 13 different operating conditions, where the process variables were controlled in the following ranges: screw speed, $200{\sim}300$ rpm; temperature, $110{\sim}130^{\circ}C$; moisture, $15{\sim}25%$. Solubilization effects of whole grains by extrusion were characterized in terms of water solubility index (WSI), viscosity, dispersibility and dietary fiber in comparison with those of raw and roasted grains. WSI of whole grains significantly increased by extrusion, especially WSI of glutinous rice containing abundant amylopectin increased twice than WSI of brown rice. The content of soluble dietary fiber was increased due to extrusion treatment, while insoluble dietary fiber decreased concomitantly and the content of total dietary fiber was not nearly changed. Extrusion improved the dispersibility and swelling effects in comparison with that of raw and roasting grains.

The study on toothbrush filaments (칫솔 강모 형태에 관한 연구)

  • Han, Seung-Min;Yang, Seung-Min;Lee, Young-Moo;Ku, Young;Rhyu, In-Chul;Chung, Chong-Pyoung;Choi, Sang-Mook;Han, Soo-Boo
    • Journal of Periodontal and Implant Science
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    • v.32 no.4
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    • pp.857-864
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    • 2002
  • The aim of this study is to investigate the end of filaments of the different toothbrushes in the market through the stereomicroscope and to evaluate the % of rounded-end filaments considered to be acceptable. 9 brands, total 11 type toothbrushes were tested. 2 toothbrushes of each type which is marked as rounded-end filaments were tested. The toothbrushes which are not marked as rounded-end filaments were excluded. The domestic as well as foreign toothbrushes which are familiar to consumers were tested. 2 tufts of each toothbrushes were cut and examined by stereomicroscope using $40{\times}$ magnification. The procedure was carried out with blind-technique, and the digital photographs were taken. Besides the % of rounded-end filaments, total tufts number, material of the tuft, stiffness, and other special characteristics were recorded. By the classification of Silverstone and Featherstone, rounded-end filaments were examined and counted. The results shows that there are different range of rounded-end filaments according to the toothbrush types(17.7%-91.2%). Atman toothbrush has the most rounded-end filaments(91.2%) among the observed toothbrushes, and the Advantage Plus(Ora1-B) has the next(86.75%). E-Clean #411 has the least(17.70%) and E-Clean #410 of the same brand has also low % rounded-end filaments(20.60%). While G.U.M #409(Butler) has 67.90% rounded-end filaments, G.U.M #471 of the Same brand has comparative low 41.83% rounded-end filaments. 4 types of total 11 have the rounded-end filaments over 80%, however other 4 types have under even 50%. Considering that the correct brushing habit with a toothbrush which has rounded-end filaments can protect the gingival injury and tooth abrasion, it is thought that we dentists need to give the correct information about toothbrush to the patients

Analysis of the ITS (Internal Transcribed Spacer) Region of Opuntia ficus-indica (백년초선인장의 ITS(internal transcribed spacer) 유전자 분석)

  • In Jun-Gyo;Lee Bum-Soo;Kim Eun-Jeong;Choi Kwan-Sam;Han Seung-Ho;Shin Cheol-Woo;Yang Deok-Chun
    • Korean Journal of Plant Resources
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    • v.19 no.1
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    • pp.161-168
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    • 2006
  • To investigate the origin of backyeoncho (Opuntia ficus-indica var. saboten), we isolated 685 bp clone using ITS primer pairs. The rDNA consists of the genes coding for the partial 54 bp 185, 162 bp 5.8S, and partial 56 bp 26S. The coding regions are interrupted by two internal transcribed spacers, 193 bp ITS1 and 220 bp ITS2. The ITS2 of backnyeoncho in length was shorter than that previously registered in Cucurbitoideae plants. The GC contents was 66.8% in ITS1, and 67.7% in ITS2. The rDNA of backnyeoncho matched to the previously reported genes and showed a high similarity with the 95% identity with Pereskiopsis porteri (L708037). In the phylogenetic analysis, the backnyeoncho rDNA was clustered with Pereskiopsis porteri (L708037).

Effect of Tumor Necrosis Factor-${\alpha}$(TNF) on the Expression of Oncogenes in ME-180 Human Cervical Carcinoma Cells (종양괴사인자(TNF)가 ME-180 사람 경부 암종세포에서 종양 발생 유전자의 발현에 미치는 영향)

  • Han, Hyung-Mee;Kim, Hyung-Soo;Sohn, Kyung-Hee;Choi, Kyoung-Baek;Chung, Seung-Tae;Kim, Jin-Ho;Lee, Byung-Moo;Kim, Joo-Il
    • YAKHAK HOEJI
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    • v.41 no.5
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    • pp.629-637
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    • 1997
  • Tumor necrosis factor-${alpha}$ (TNF) induced a cytotoxic response in ME-180 cervical carcinoma cells in vitro. This cytotoxic response was accompanied by a temporal series of mitogenic stimuli : increased c-fos, c-jun and jun-B expression. Depletion of protein kinase C (PKC) by exposure of ME-180 cells to 100ng/ml phorbol myristate acetate (PMA) for 24hours almost completely abolished TNF-mediated increase in these signals, indicating that a PKC-dependent pathway is involved in TNF-mediated increases in the expression of c-fos, c-jun and jun-B. Characteristics of TNF receptors after exposure to 100ng/ml PMA or 24hours were not altered, suggesting that diminished induction of these oncogenes by TNF after PMA treatment is not due to any changes at the receptor level. To examine whether a PKC-dependent pathway is involved in TNF-mediated cytotoxicity in ME-180 cells, cytotoxicity was measured after depletion of PKC. No apparent changes in cytototoxicity after PKC depletion suggest that a PKC-dependent pathway is not involved in TNF-mediated cytotoxicity. Furthermore, results from cytotoxicity tests after exposure to staurosporine (PKC inhibitor) did not show any changes in the TNF-mediated cytotoxicity, confirming that a PKC-dependent pathway is not involved in this process. These data indicate that 1) TNF induces expression of c-fos, c-jun and jun-B oncogenes via a PKC-dependent pathway and 2) PKC-dependent expression of these three oncogenes by TNF may not be involved in TNF-mediated cytotoxicity in ME-180 cells.

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