• Journal of Oral Medicine and Pain
• /
• 제48권3호
• /
• pp.96-105
• /
• 2023

Purpose: Mandibular advancement devices (MAD) are known to be insufficiently effective in all patients with obstructive sleep apnea (OSA). This study aimed to compare the treatment outcomes of MAD therapy according to OSA severity and to investigate the risk factors for the lack of response to MAD therapy. Methods: A total of 29 patients diagnosed with OSA received an adjustable two-piece MAD treatment. Sleep parameters measured with the home sleep apnea test device, including apnea-hypopnea index (AHI) and oxygen saturation (SpO₂), and daytime sleepiness using the Epworth Sleepiness Scale (ESS) were retrospectively assessed both before and after the MAD treatment. Results: The patients were classified into three groups according to AHI severity: mild (n=16, AHI<15), moderate (n=6, 15≤AHI<30), and severe OSA (n=7, AHI≥30). MAD therapy significantly improved the sleep parameters (p<0.001 for AHI and p=0.004 for minimum SpO₂) and daytime sleepiness (p<0.001 for ESS). Furthermore, successful outcomes (reduction in AHI>50% and AHI<10 events/h) were achieved in 83.3% and 71.4% of moderate and severe OSA cases, respectively. Of 13 patients with moderate and severe OSA, 10 were classified as responders and 3 as non-responders. The non-responders had significantly lower baseline value of SpO₂ (p=0.049 for average SpO₂ and p=0.007 for minimum SpO₂) and higher baseline AHI (p=0.049) than the responders. Conclusions: The results of the present study suggest that MAD is effective in the majority of patients with OSA of varying severities. The success of MAD therapy does not seem to depend solely on AHI severity. In addition to AHI, minimum SpO₂ may be a prognostic measure of the efficacy of MAD treatment in clinical dental practice.

• 대한한방내과학회지
• /
• 제39권4호
• /
• pp.802-813
• /
• 2018

This case report describes a patient with olivopontocerebellar atrophy accompanied by sleep disorder and gait disturbance whose condition was improved by treatment with Korean medicine. The 61-year-old woman, who was diagnosed with olivopontocerebellar atrophy (Multiple Systemic Atrophy-Cerebellum), was admitted to hospital twice and treated with Korean medicine (acupuncture and herbal medicine) and rehabilitation. The Korean medicine was Gwibiondam-tang-gami and Jaeumgeonbi-tang-gami. Clinical symptoms were assessed by the Modified Bathel index, functional independent measurement, Berg balance scale, and Unified Multiple System Atrophy rating scale. A brain MRI at the one-year follow up after onset showed similar progress but clinical symptoms were improved after treatment, and the evaluation index score increased. Multiple system atrophy, a type of degenerative neurological disease, has no targeted treatment. In this situation, although this report describes a single case, Korean medicine treatment could provide a meaningful improvement in the sleep disturbance and gait disorder symptoms of patients with olivopontocerebellar atrophy.

• 농촌의학ㆍ지역보건
• /
• 제38권2호
• /
• pp.97-107
• /
• 2013

기면병 환자들은 과도한 주간 졸음증, 탈력발작, 수면마비, 입면시 환각 외에도 야간 수면의 장애를 가지고 있다는 것을 알 수 있었다. 주의, 기억 그리고 집행에 대한 인지기능을 평가한 결과 d2 의 경우 전체 수행을 한 총 넘버수, 지속적이 수행이 요구되는 과제인 정반응 수(TN-E), 집중력 지표(CP), 그리고 과제를 수행하는데 일관성과 안정성을 평가하는 변동률(FR)에서 기면병 환자군의 점수가 대조군에 비해 통계적으로 유의하게 낮았다. 이는 기면병 환자의 주의력에 결함을 시사한다. 또한, K-CVLT 검사의 B 목록의 경우 기면병 환자군에서 대조군에 비하여 저조한 수행을 보여 언어성 주의력에 저하를 시사한다. 무엇인가를 기억하기 위해서는 한 가지에 주의를 기울여야 하기 때문에 주의와 기억은 밀접하게 관련되어 있으므로 주의력은 기억이나 집행기능 등의 상위인지기능의 수행에도 영향을 줄 수 있다. 따라서 기면병 환자들에서 기존에 보고되었던 주의력 이외의 인지기능 저하는 실제로 주의력 저하에 의한 이차적인 현상으로도 생각해 볼 수 있다. 기면병은 개인의 삶의 질적인 측면뿐 아니라, 인지기능 저하로 인해 사고가 증가시킨다는 점은 공중보건학적으로도 중요한 문제임에도 불구하고[26], 기면병 환자의 주의, 기억, 그리고 집행에 대한 인지기능을 포괄적으로 평가하는 연구는 거의 이루어지지 않았다. 이 연구는 기면병 환자에서 주의, 기억 그리고 집행기능에 대한 포괄적인 신경심리검사를 통하여 인지기능을 평가하였고, 인지기능의 재활 및 개선을 위한 유용한 자료로서 의의가 있다.

• 수면정신생리
• /
• 제24권1호
• /
• pp.55-61
• /
• 2017

목 적 : 자살은 정신과 영역에서 큰 과제이며 특히 대한민국에서 자살은 젊은 성인들에서 주요한 사망원인이기도 하다. 따라서 지역 대학생들의 불안, 수면의 질이 자살사고와 어떠한 연관성이 있는지 알아보고자 하였다. 방 법 : 진주지역의 한 공과대학교 재학생 1094명을 대상으로 하였다. 자살생각척도, 병원 불안-우울 척도, 한국판 피츠버그 수면의 질 척도, 아침형-저녁형 설문지를 사용하였다. 자살사고척도가 높은 군과 낮은 군으로 나누어 두 군에서 유의미한 차이를 보이는 요인들에 대해 다중회귀분석을 수행 하였다. 결 과 : 자살사고 평가에 답한 292명의 학생들 중 자살사고가 높은 군은 31명 이었다. 두 군에서 유의미한 차이를 보이는 인구학적 변수는 성별, 운동여부, 일주기리듬, 수면의 질, 우울 그리고 불안 이었다. 이 변수들과 자살사고와의 관계성을 파악해 보기 위해 다중회귀분석을 시행한 결과 불안이 높을수록 수면의 질이 낮을수록 자살사고가 증가하는 것을 확인 하였다. 우울과 일주기리듬의 경우 유의한 관련성을 보이지 않았다. 수면의 질과 연관된 수면-관련 요인들의 특성을 파악하기 위해 다중회귀분석을 시행하였고 주말의 과수면 시간이 늘어날수록 수면의 질이 낮아지는 것을 확인하였다. 결 론 : 본 연구결과 지역 대학생들에서 불안이 심할수록, 그리고 수면의 질이 나쁠수록 자살사고가 증가하는 것을 확인하였다, 따라서 주말의 과수면을 줄여 수면의 질을 개선하고 불안을 줄이는 것이 자살사고를 줄이는 데 중요하다.

• Annals of Occupational and Environmental Medicine
• /
• 제35권
• /
• pp.25.1-25.12
• /
• 2023

Background: In Korea, little research has focused on the relationship between discrimination in the workplace and sleep health. Thus, this study aims to investigate the association between such discriminatory experiences and insomnia, a common sleep disorder, using Korean employees' data. Methods: This study used data from the 6th Korea Working Conditions Survey. Discrimination experiences due to age, ethnic background, nationality, race, sex, religion, disability, sexual orientation, educational level, hometown, and employment status were investigated. The Minimal Insomnia Symptom Scale estimated insomnia symptoms. The association between discrimination experience and insomnia symptoms were analyzed using survey-weighted logistic regression analysis. Results: Based on experiences of discrimination over the past 12 months, insomnia symptoms were associated with discrimination experience due to religion (odds ratio [OR]: 3.70; 95% confidential interval [CI]: 1.58-8.69), sex (OR: 2.51; 95% CI: 1.87-3.37), age (OR: 2.30; 95% CI: 1.88-2.81), hometown (OR: 2.07; 95% CI: 1.44-2.97), employment status (OR: 1.69; 95% CI: 1.37-2.10), and educational level (OR: 1.67; 95% CI: 1.31-2.14). Furthermore, the prevalence of insomnia symptoms increased with the number of discrimination experiences. Conclusions: In this study, discrimination experiences due to religion, sex, age, hometown, employment status, and educational level were significantly associated with insomnia symptoms. Furthermore, as the number of discrimination experiences increased, so did the prevalence of insomnia. Preventing workplace discrimination may improve workers' sleep health.

• Journal of Rhinology
• /
• 제25권2호
• /
• pp.69-74
• /
• 2018

Background and Objectives: Sleep disturbances and excessive daytime sleepiness (EDS) are the major symptoms of obstructive sleep apnea (OSA). This study aimed to investigate clinical implications of insomnia and EDS in patients with OSA using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS). Materials and Method: We evaluated 131 subjects with suspected OSA who were undergoing polysomnography (PSG) and performing the PSQI and ESS surveys. OSA was diagnosed when the apnea-hypopnea index was five or more. EDS was defined when ESS score was 11 points or higher. Detailed history and questionnaire were used to categorize insomnia. We compared clinical variables and PSG results in subgroups with or without insomnia and EDS. Results: There were no significant differences of PSQI and ESS score between controls and OSA. OSA with insomnia had significantly increased total score (p<0.001) and decreased total sleep time (p=0.001) and sleep efficiency (p=0.001) on the PSQI compared to those without insomnia. OSA with EDS showed significantly increased PSQI score (p=0.022) and decreased total sleep time (p=0.018) on PSG compared to those without EDS. Neither PSQI nor ESS score had a correlation with respiratory variables such as AHI and oxygen saturation. Total sleep time had a significant effect on both insomnia and EDS in patients with OSA. Conclusion: Decreased total sleep time had important effects on subjective symptoms of OSA and comorbid insomnia. Therefore, restoration of decreased sleep time is important in the management of OSA.

• 대한한방내과학회지
• /
• 제39권5호
• /
• pp.895-903
• /
• 2018

Objectives: This study reports on the efficacy of using integrative Korean medical treatments for Type 1 complex regional pain syndrome (CRPS). Methods: A 48-year-old female patient with Type 1 R/O CRPS was treated with herbal medicines, acupuncture, and pharmacopuncture for 38 days. The chief complaints were severe burning pain, general weakness, sleep disorder, and aggressive and depressed mood. The treatment effect was evaluated by measuring the numerical rating scale (NRS) of pain, improvement of the quality of sleep, and change in mood status. Results: After the hospital treatment, the patient's pain was controlled and the NRS score was decreased. Sleep and mood disorder also improved. Conclusions: The integrative Korean medical treatments appeared to be effective in reducing Type 1 CRPS symptoms. Further clinical research of patients with CRPS is needed.

• 여성건강간호학회지
• /
• 제16권2호
• /
• pp.95-104
• /
• 2010

Purpose: This study examined the influencing factors on antenatal depression among pregnant women. Methods: This was a cross sectional descriptive study with 255 pregnant women who visited a general hospital in a metropolitan city for their regularly scheduled check-up. Measurement tools employed were the Korean version of Beck Depression Inventory (BDI), the food habits, and the Pittsburg Sleep Quality Index (PSQI). Socio-demographic variables and the status of high risk pregnancy were identified. Influencing factors on antenatal depression were identified using a stepwise multiple regression analysis. Results: The mean score of antenatal depression was $7.2{\pm}5.0$; 18.4% with mild depression, 5.9% had moderate depression, with 0.8% identified with severe depression on BDI scale. Influencing factors on antenatal depression accounted for 47.8% of the total variance which consisted of quality of sleep, marital satisfaction, food habits, gestation periods, sexual satisfaction, high risk pregnancy, and age. Conclusion: Findings show that antenatal depression should be monitored on a regular basis during early pregnancy and in high risk pregnancy if possible, and quality of sleep and food habits should be incorporated in the management of antenatal depression.

• 성인간호학회지
• /
• 제22권5호
• /
• pp.457-465
• /
• 2010

Purpose: This study was conducted to examine the degrees of depression and activities of daily living (ADLs), and to identify factors that predict depression in elderly patients. Methods: The sample was149 patients (80% female; mean age 79.1) from three geriatric hospitals located in small cities and who agreed to participate in the study. Data were collected by staff nurses involved in direct patient care from October to September 2009. The level of depression was measured on a daily basis for seven days using a 13-item scale. Patients' ADLs was measured using a modified 10-item Bathel ADLs scale. Data were analyzed using SPSS/WIN 17.0. Results: Mean depression score was $10.05{\pm}4.77$ out of 26 points and about 27% was assessed as depressed with more than 13 points. Multiple regression analysis showed that low educational level, absence of spouse and fewer family visits predict depression. In addition, low ADLs and sleep disturbance predict depression. Conclusion: Nursing care providers need to be concerned about ADLs of older patients and should develop nursing activity programs to increase their in-hospital physical activities. It is also important care for older patients' sleep and encourages family visits to decrease their depression.

• Journal of Oral Medicine and Pain
• /
• 제41권2호
• /
• pp.54-60
• /
• 2016

Purpose: Mandibular advancement devices (MAD) are used effectively and widely for the treatment of obstructive sleep apnea (OSA) and rapid-eye-movement (REM) dependency of the patients can affect the treatment outcome of OSA. The aim of this study was to compare treatment outcomes of MAD between REM-related and not-REM-related OSA patients. Methods: Fifty-six consecutive patients with OSA who received MAD therapy were evaluated using full night polysomnography before and after insertion of the MADs. The patients were divided into REM-related (REM apnea-hypopnea index [AHI] at least two times higher than their non-REM AHI) and not-REM-related (REM AHI less than two times higher than their non-REM AHI) OSA groups. Results: MAD is used for the treatment of OSA effectively. In respect of AHI, MAD therapy were effective both in REM-related OSA and not-REM-related OSA, but MAD therapy was more effective in not-REM-related OSA than REM-related OSA in overall sleep and non-REM sleep. $SpO_2$ saturations were improved after MAD therapy, but were not different between two groups. Epworth sleepiness scale scores were not improved after MAD therapy. Percentage of REM sleep was increased after MAD therapy but was not different between two groups. Conclusions: MAD therapy was more effective in not-REM-related OSA than REM-related OSA and REM dependency can be a predictive factor of treatment outcome of oral appliance for OSA patients.