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The study on the selection of Sasang Constitution-specific herbs in 『Dongyisusebowon Sinchuk-Bon』 from TCMID and TCMSP (중의학 데이터베이스인 TCMID와 TCMSP로부터 『동의수세보원 신축본』에 제시된 사상체질별 본초 선별 연구)

  • Kim, Ji Hwan
    • Journal of Sasang Constitutional Medicine
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    • v.31 no.3
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    • pp.19-33
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    • 2019
  • Objectives The network pharmacological study on herbal remedies in Traditional Chinese Medicine (TCM) is actively being carried out based on the TCM databases such as TCMID and TCMSP. It is necessary to select Sasang Constitution-specific (SC-s) herbs from these databases in order to study the prescriptions in Sasang Constitutional Medicine. Methods SC-s herbs and their processing types listed in "Dongyisusebowon Sinchukbon" were searched from TCMID and TCMSP. Results and Conclusions 1. There were total 144 herbs (Soeum 47, Soyang 37, Taeeum 44, Taeyang 16 specific herbs) listed in "Dongyisusebowon Sinchukbon". 2. There were total 130 herbs (Soeum 43, Soyang 37, Taeeum 42, Taeyang 8 specific herbs) searched from TCMID, and total 92 herbs (Soeum 31, Soyang 30, Taeeum 27, Taeyang 4 specific herbs) from TCMID. 3. In some cases, the name given in "Dongyisusebowon Sinchukbon" was different from that in TCMID and TCMSP. It was needed to be careful during the searching process. 4. Although the processing form of some herbs could be searched, there was a significant reduction in the herbal compound information compared to the raw form. It is necessary to reconsider whether or not to use the processing form. 5. Herbal scientific names given in TCMID and TCMSP or used in China and Korea were different each other in some cases. Additional screening process among such herbs would be required based on the efficacy of herbs used in clinical field.

Anatomical and Ecological Characteristics of Marine Biotoxin-Bearing Mollusks (해양독소를 보유한 연체동물의 기관별 명칭과 생태학적 특성에 관하여)

  • Hong, Hyun-Ki;Kajino, Nobuhisa;Kim, Hyoun Joong;Lee, Wan Ok;Lee, Jihyun;Choi, Kwang-Sik
    • Journal of Food Hygiene and Safety
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    • v.36 no.6
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    • pp.455-473
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    • 2021
  • In order to aid the researchers who analyze the biotoxins in marine molluscs, this paper introduces the official names and ecological characteristics of the domestically produced or distributed bivalve and gastropods that can be contaminated with marine biotoxins. Also, the paper intends to inform the location and scientific name of each organ of the representative group of species through anatomical maps. In the future, it is necessary to standardize and normalize the names of the species and the research institutions in food codes, scholarly papers and reports on the marine biotoxin analysis.

A Phenomenological Study on Experience of Sexual Offender in Prison (수감되어 있는 성폭력 가해자의 경험에 대한 현상학적 연구)

  • Han, In-Young;Kim, Jin-Sook;Kim, Ji-Hae
    • Korean Journal of Social Welfare Studies
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    • v.42 no.3
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    • pp.121-155
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    • 2011
  • The purpose of this study as a research of experience of sexual offenders who are in confinement in prisons and forensic facilities is to theoretically investigate fundamental structures of their experiences and to practically construct basic data to present intervention programs of sexual offenders. This study was conducted by hermeneutical and phenomenological methods invoked of the analytic framework of Van-Manen (1990) about seven sexual offenders. The data were collected through in-depth interviews, and the results of the interpretation are shown as perception that they were victims of public opinion, the mark of Cain, loss of opportunity of examination caused by show window, collective differentiation through distinction, expression of metaphysical being that wants to slip out of the skin, counterplot of scientific management techniques, undifferentiation from the Imaginary, sexual acts shown as inverted communication, discovering dominant domain as forming reaction to being controlled, not being free from capitalistic attributes in which even children's sex is commercialized, distortion in socialization of sexual identity, paternity stamped as embodiment of suppressed desire, recovery of lost virginity of mother through children, and family as a name broken to pieces.

The study about the cause of the Korean professional pitchers' injury and its classification (한국 프로야구투수들의 부상 발생원인 및 분류에 관한 연구)

  • Nam Joung-Chul;Kim Sang-Su;Lee Dong-Ho
    • The Journal of Korean Physical Therapy
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    • v.14 no.4
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    • pp.172-182
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    • 2002
  • Objectives: We did research in the cause of the Pitchers' injury and their recovery process to make a detailed injury list for the purpose of finding the cause of the Korean professional pitchers' injury and its classification. We drew the conclusion through the results as following. Methods: We posed a question to the 80 pitchers playing in the first team of the eight Korean professional baseball team and analyzed the 62 pieces of question paper except the paper having a mistake. We used SAS/PC statistical package in analyzing the data. Results: In the frequency of the pitchers' shoulder injury in the last three years, the injured of all the players were 61.3$\%$ and the injury free players were 28.7$\%$. The cause of the injury was 45.2$\%$ wrong pitching motion, which was the highest value. For the shape of a pain when injured, the reverberation ache feeling when he is hit in the weight commanded an absolute majority as 19.4$\%$. Those who had muscular pain were 17.7$\%$, which was felt mostly at the pitching motion. The most trouble name of the injured shoulder was bicepstendinitis as 16.1$\%$ while the injury of shoulder joint was the lowest as 1.6$\%$. As the most widely used treatment, 25.8 percent of all the players had taken an electronical thraphy after injury. 14.5 percent of the players who had an injury to the shoulder told that they have an operation and 85 percent of them didn't. As a sort of the operation, a repairing of labrum was 44.4 percent, which is the highest value and the 77.8 percent pitchers are performing a normal pitching through rehabilitation after the operation and 22.2 percent of them are undergoing rehabilitation training. Conclusion: The research have shown that the main cause of the injury, concerning the Korean professional pitchers throwing lots of ball in both matches and practices, is overuse syndrome, bad mechanism, muscle weakness and instability of balance. I think that the role of trainer, physical therapy, and team physician taking charge of the players' injury must learn physical test method by heart exactly to check up the state of the injury definitely at the initial phase. Moreover, when the cause of the injury part after a close examination is discovered, the scientific and good surgery is essential to the rehabilitation success and making a classification of shoulder instability is useful to make a operation plan as well as the players' rehabilitation, treatment.

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Effect of Hoelen in RANKL-induced Osteoclast Differentiation (파골세포 분화에 복령 추출물이 미치는 영향)

  • Cheon, Yoon-Hee;Kwack, Seong-Cheoul;Oh, Jae-Min;Choi, Min-Kyu;Kim, Jeong-Joong;Kwak, Han-Bok;Lee, Myeung-Su;Jeon, Byung-Hoon;Moon, Seo-Young
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.3
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    • pp.320-324
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    • 2012
  • Osteoporosis is an important public health issue in postmenopausal women. It is a major public health concern and is widely believed that osteoporosis results from imbalance between bone resorption and bone formation. Recently natural products from plants have been extensively studied as therapeutic drugs to treat and prevent various diseases. Hoelen (scientific name, Poria cocos) is a mushroom that is used in traditional Chinese medicine. Hoelen exhibits anti-inflammatory activity and has a protective effect on tumor progression. However, the effect of hoelen in osteoclast differentiation remains unknown. Thus, we examined the effect of hoelen in receptor activator of nuclear factor-${\kappa}B$ ligand (RANKL)-induced osteoclast differentiation. Hoelen significantly inhibited RANKL-induced osteoclast differentiation in bone marrow-derived macrophages (BMMs) in dose dependent manner without toxicity. Also, we showed that hoelen significantly inhibited the mRNA expression of tartrate-resistant acid phophatase (TRAP) and nuclear factor of activated T cells 1 (NFATc1) in BMMs treated with RANKL. In Particular, hoelen greatly inhibited the protein expression of NFATc1. Ectopic expression of NFATc1 partially reverses hoelen-mediated inhibition of osteoclast differentiation. Taken together, our results demonstrated that hoelen may be useful treatment option of bone-related disease such as osteoporosis, reumatoid arthritis, and periodontitis.

Progress and Prospect of Research on Old Maps in Korea (우리나라 고지도의 연구 동향과 과제)

  • Kim, Ki-Hyuk
    • Journal of the Korean association of regional geographers
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    • v.13 no.3
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    • pp.301-320
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    • 2007
  • In Korean academic societies, old maps has not yet been properly investigated in terms of their genealogy, classification, detailed place names, historical backgrounds and the other aspects. With publication of the bibliographies and papers on old maps reserved in museum and library, the scope of research enlarged gradually its scope from 1970s. In 1980s, with the development of theoretical geography, scientific analysis were applied to investigate the projection method of Daedongyeo-jido. The 1990s proved a prominent decade for researches. The photo-copies of old maps enabled researchers to investigate the in-depth comparative study. The more important thing is that old maps became to be powerful instrument in the research of historical geography, such as territorial disputes and marine name(東海). And county old maps compiled by region became to be regional-cultural contents of local areas. Important issues in old map research in Korean academic societies are about Cheonha-do which is unique old world map in Korea, grid-system projection in old county maps and the genealogy of Daedongyeo-jido(manuscript and block print edition). This study shows that bibliography of all old maps preserved in each library and museum should be standardized. This could enable the exchange of information of old maps between institutes. The more important thing is that conciliation of human, social and natural sciences should be applied in the research of old maps.

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A phylogenetic analysis of Korean Artemisia L. based on ITS sequences (ITS 염기서열에 의한 한국산 쑥속(Artemisia L.)의 계통분류학적 연구)

  • Lee, Jeong-Hoon;Park, Chung-Berm;Park, Chun-Geon;Moon, Sung-Gi
    • Korean Journal of Plant Resources
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    • v.23 no.4
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    • pp.293-302
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    • 2010
  • Taxa of Artemisia collected in Korea were constructed by molecular phylogenetic analysis based on the internal transcribed spacer(ITS) regions of nrDNA. The length of the ITS sequences aligned using the clustal X program was 636~643 bp, and the lengths of the ITS1 and ITS2 regions were 251~255 bp and 217~222 bp, respectively. The total number of variable sites was 95 for the entire sequence, and a parsimony- informative site represented an efficacious site in ITS1 rather than in ITS2. The maximum parsimony tree as calculated by the MEGA 4 program was clustered into five clades. The taxa(A. capillaris, A. japonica var. japonica, A. japonica var. hallaisanensis, A. japonica subsp. littoricora) degenerated ovary of clade 1 was supported as the subgenus Dracunculus by Ling's classification system. The results show that A. nakaii and A. fukudo were quite similar genetically(Boostrap 99%) and that the scientific name of Korean A. dubia should be reconsidered. A. sp. distributed in Ganghwa province was grouped with A. argyi(Boostrap 89%). These results suggest that the molecular techniques used in this study could be useful for the phylogenetic analysis of Korean Artemisia herbs having variations in their morphological characteristics.

Species Identification and Monitoring of Labeling Compliance for Commercial Pufferfish Products Sold in Korean On-line Markets (국내 온라인 유통 복어 제품의 종판별 및 표시사항 모니터링 연구)

  • Ji Young Lee;Kun Hee Kim;Tae Sun Kang
    • Journal of Food Hygiene and Safety
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    • v.38 no.6
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    • pp.464-475
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    • 2023
  • In this study, based on an analysis of two DNA barcode markers (cytochrome c oxidase subunit I and cytochrome b genes), we performed species identification and monitored labeling compliance for 50 commercial pufferfish products sold in on-line markets in Korea. Using these barcode sequences as a query for species identification and phylogenetic analysis, we screened the GenBank database. A total of seven pufferfish species (Takifugu chinensis, T. pseudommus, T. xanthopterus, T. alboplumbeus, T. porphyreus, T. vermicularis, and Lagocephalus cheesemanii) were identified and we detected 35 products (70%) that were non-compliant with the corresponding label information. Moreover, the labels on 12 commercial products contained only the general common name (i.e., pufferfish), although not the scientific or Korean names for the 21 edible pufferfish species. Furthermore, the proportion of mislabeled highly processed products (n = 9, 81.8%) was higher than that of simply processed products (n = 26, 66.7%). With respect to the country of origin, the percentage of mislabeled Chinese products (n = 8, 80%) was higher than that of Korean products (n = 26, 66.7%). In addition, the market and dialect names of different pufferfish species were labeled only as Jolbok or Milbok, whereas two non-edible pufferfish species (T. vermicularis and T. pseudommus) were used in six commercial pufferfish products described as JolboK and Gumbok on their labels, which could be attributable to the complex classification system used for pufferfish. These monitoring results highlight the necessity to develop genetic methods that can be used to identify the 21 edible pufferfish species, as well as the need for regulatory monitoring of commercial pufferfish products.

A study on the Evaluation of Reading Ability for the Literature Reading of Korean College Students: the Freshmen of A University (우리나라 대학생들의 문헌 독해능력 평가 연구 - A대학 1학년생을 대상으로 -)

  • Lee, Jong-Moon
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.21 no.3
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    • pp.17-27
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    • 2010
  • This study aimed to identify the problems of college students in reading the literature and on the basis of the identified problems, to suggest the approaches to solve the problems. To this end, time required for reading passages, reading patterns, understanding, memory and reading habits and attitudes were analyzed with the freshmen in A university. In accordance with the analysis results, 58% of subjects was good and 42% was not sufficient on the basis of the averages in Scholastic Aptitude Test. Second, 77% of subjects had the good patterns but 23% showed certain problems in reading patterns. Third, 69% and 67% of subjects illustrated good results in the analysis on understanding and memory, respectively. However, 31% and 33% were evaluated as being on the general level or requiring efforts in the analysis on understanding and memory, respectively. Next, according to the analysis on reading habits and attitudes, 77% had no problems but 23% required improvement. For solving the problems identified through the analysis, it is recommended to develop the scientific and standardized evaluation tools for evaluating the reading ability of college students. Second, it is necessary to evaluate the reading ability, habit and attitude during the screening process for admission or after admission. Finally, it is required to operate the Fundamental Academic Ability Learning Center(tentative name) to improve the ability of students who show the insufficient results in evaluation.

Discordance between Morphological and Molecular Variations of the Genus Macroramphosus (Macroramphosidae) from Korea (한국산 대주둥치속(대주둥치과) 어류의 형태와 분자 변이의 불일치)

  • Sohn, Min-Soo;Kim, Jin-Koo
    • Korean Journal of Ichthyology
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    • v.32 no.4
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    • pp.199-209
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    • 2020
  • In order to clarify the taxonomic status of the Korean Macroramphosus species, which were previously confused, we investigated morphological and molecular variations of Macroramphosus (18 individuals) from Korea, and Macroramphosus (35 individuals) from Japan and Taiwan, and compared with those of M. scolopax from type locality (Mediterranean Sea). Although the Korean and Japanese specimens of Macroramphosus were clearly divided into two types in the first dorsal spine length (22.8~32.1% in A-type vs. 15.6~21.4% in B-type), distance between the first dorsal fin and second dorsal fin (6.4~9.7% vs. 8.6~13.3%), and body depth (20.0~28.0% vs. 17.3~22.6%), no genetic differences among all individuals of longspine snipefish between them were found at the specific level [d=0.0~3.3% in control region (CR); 0.0~1.3% in cytochrome b (cytb); 0.0~0.5% in cytochrome c oxidase subunit I (COI)]. Whereas, they were well distinguished in genetics (9.9~11.5% in CR; 3.8~4.6% in cytb; 1.2~3.6% in COI) from those of M. scolopax in Mediterranean Sea. It needs the scientific name of the longspine snipefish (M. scolopax) in Korea be changed as M. japonicus (and/or M. sagifue). However, our results could not find evidence of consistency between morphological and mitochondrial DNA variations which suggests that their differentiation event may occur fairly recently. Further studies using more sensitive markers such as microsatellite are needed to clarify the degree of gene flow between the two types.