Kwak, Jin Il;Cui, Rongxue;Moon, Jongmin;Kim, Dokyung;An, Youn-Joo
Journal of Korean Society of Environmental Engineers
/
v.39
no.3
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pp.132-139
/
2017
Endocrine disrupting chemicals (EDCs) interfere with endocrine system in organisms, and have different mode of actions compared to conventional chemicals. Therefore, EDCs specific ecotoxicity tests and assessments have been globally developed by some organizations such as OECD, ASTM, and USEPA. In Korea, researches on EDCs and monitoring of EDCs in domestic environments were also continued. However, Korean ecotoxicity test guidelines for EDCs are not suggested till date. The purpose of this study is to review and analyze international ecotoxicity test guidelines for EDCs and the compare ecotoxicity methods and toxicity endpoints among standard test guidelines. We found that there are very limited EDCs specific soil ecotoxicity test guidelines (only in ASTM) compared to aquatic ecotoxicity test guidelines. Currently, fish, amphibian, waterflea, copepoda, earthworm, white worm, springtail, nematode, mite, and midge are suggested as standard ecotoxicity test species for EDCs. Reproduction, hormones, growth, vitellogenin, sex retio and development were proposed as endpoints for EDCs ecotoxicity. This study provided the comparison of EDCs specific ecotoxicity methods and endpoints between standard test guidelines, and suggested the further research to develop the method for assesseing ecotoxicity of EDCs.
Objective: Multi-regional clinical trials have been widely used for accelerating global drug development by multinational pharmaceutical companies. In this study, we aimed to review and analyze the international trends in regulations and guidelines on multi-regional clinical trials by regulatory authorities and international organizations, such as International Conference on Harmonisation, for referring to policies, including development of domestic guidelines for multi-regional clinical trials. Methods: The policies, regulations, and guidelines published by the US Food and Drug Administration, European Medicines Agency, Pharmaceuticals and Medical Devices Agency (Japan), and China Food and Drug Administration were searched, and the International Conference on Harmonisation E17 draft guideline was reviewed. Results: The regulatory authorities in developed countries have developed and implemented regulations and guidelines on multi-regional clinical trials to promote simultaneous global drug development and evaluate the regional differences in drug safety and efficacy. International Conference on Harmonisation developed the draft guideline for planning/designing of multi-regional clinical trials in 2016, which recommends the general principles for strategy-related issues and design of multi-regional clinical trials, and for protocol-related issues, such as consideration of regional variability, subject selection, dose selection, endpoints, comparators, overall sample size, allocation to regions, collecting information on efficacy and safety, and statistical analysis. Conclusion: It is important to understand the international regulatory requirements for designing and planning of multi-regional clinical trials for global drug development. Moreover, it is necessary to prepare multi-regional clinical trial guidelines in accordance with the Korean regulation for clinical trials and drug administration.
High-resolution satellites capable of observing the Earth periodically enhance applicability of remote sensing in the field of national disaster management from national disaster pre-monitoring to rapid recovery planning. The National Disaster Management Research Institute (NDMI) has been developed various satellite-based disaster management technologies and applied to disaster site operations related to typhoons and storms, droughts, heavy snowfall, ground displacement, heat wave, and heavy rainfall. Although the limitation of timely imaging of satellite is a challenging issue in emergent disaster situation, it can be solved through international cooperation to cope with global disasters led by domestic and international space development agencies and disaster organizations. This article of special issue deals with the scientific disaster management technologies using remote sensing and advanced equipments of NDMI in order to detect and monitor national disasters occurred by global abnormal climate change around the Korean Peninsula: satellite-based disaster monitoring technologies which can detect and monitor disaster in early stage and advanced investigation equipments which can collect high-quality geo-information data at disaster site.
Journal of Korean Society of Archives and Records Management
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v.21
no.4
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pp.117-135
/
2021
Condition assessment of analog records is enforced to establish a preservation strategy and identify the damaged records by the Public Records Management Act and the public standard in Korea. However, the number of record management organizations where the condition assessment according to the act and the standard are actually conducted is limited in Korea. To find out what to change in the system and the practice of the condition assessment, the system and situation on the condition assessment of the paper-based records in Korea and other countries were investigated through literature research and a survey. Whereas Korean archives try to assess entire individual records, archives and libraries overseas apply condition assessment selectively depending on not only historical and cultural values of the records but also the vulnerability of compositional materials and severity of the damage of the records. It seems that archives and libraries overseas have a specific reason to conduct the assessment. Most of them take advantage of a sampling method not assessing every single item. Moreover, the periodical assessment is carried out in only about 50% of the responses. Therefore, we have to consider changing our condition assessment system to a more efficient and flexible way, adopting a sampling method and applying the assessment for selective collections with more specific purposes.
Journal of Korean Library and Information Science Society
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v.53
no.3
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pp.137-168
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2022
The purpose of this study is to suggest a plan for establishing SR (systematic review, hereinafter called SR) support services in domestic university libraries through a case study of SR support services in overseas university libraries. For this purpose, a total of 119 overseas university libraries were divided into all fields (subjects and disciplines) and the medical field. And A total of 10 areas such as service fields, service subjects, public relations, librarian roles (counselors, collaborators), education, librarian introduction, team member, application form, SR theoretical content, and others were divided and investigated. As a result, the SR support service of the university libraries being investigated is expanding from the medical field to academic fields such as natural science, engineering, and social science. It was confirmed that there were differences in service support hours, services, and whether co-authors were recognized according to the role of the librarian. Educational services are provided to users for the SR support service with a focus on retrieval strategy and skills. In the promotion of the SR support service, the librarian must suggest that it should be included. The importance of SR support services for Korean university libraries should be emphasized through the analysis of SR support services for overseas university libraries, professional search education should be strengthened in the curriculum. Also Organizations related to university libraries such as KERIS have suggested that systematic SR education support is needed for librarians.
Journal of the Korean Society for information Management
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v.40
no.2
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pp.211-241
/
2023
With rapidly changing technological implementation of operating systems of businesses, the Ministry of foreign affairs (MOFA) of the Republic of Korea (ROK) has been undergoing digital transformation to its overall operations with the intent to innovate information and knowledge management (IKM) strategies since the mid-2000s. However, assessment as to the effectiveness of implemented IKM has been inadequately analyzed. This study aims to assess the concepts and limitations of the MOFA's current IKM strategies and the methods it employs to deliver its IKM framework, in light of strengthening the organizational ambidexterity and absorptive capacity, and also fostering organizational innovation through a qualitative study that involves interviews and analysis of reports from MOFA. The MOFA's IKM possesses dynamic capabilities to adapt to changing digital technologies. However, the institution's IKM is constrained by limitations associated with the utilization of the IKM system such as a structure that handles confidential documents and a lack of a collaborative system for IKM, and external limitations such as changes in the domestic political situation governing MOFA's priorities and the hierarchy of government organizations. Consequently, developing the organizational ambidexterity and absorptive capacity was not possible. To develop an IKM framework for organizational innovation, the MOFA must devise a way to minimize the impact of external changes by overcoming internal limitations. To that end, a detailed study on the development of a practically usable IKM system should include establishing a dialogue between job groups and enhancing employee competency in preparation for a changing environment.
Journal of the Korean Association of Geographic Information Studies
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v.14
no.1
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pp.59-72
/
2011
The research of psychological supporting systems as safety and welfare for disaster victims damaged psychologically as well as physically by a sudden disaster to return to effectively their social life has been carried. The domestic National Emergency Management Agency(NEMA) is operating the Disaster Victim Psychology Support Center that helps with curing damaged psychology and studies the transmission system of psychology management services, the classification of victims for disaster psychology support, and emergency consultation method to systemically support disaster psychology management. However, current psychology supporting centers provide the simple information for supporting centers such as medical and social welfare organizations. The development research of IT-based management systems to obtain needed information to construct the proposed systems curing psychological damage is still primitive step. Therefore, this paper shall propose a GIS-based integrated management system for victims and managers to effectively share related information one another and to return to victims' social life as soon as possible. Also, we implement a simple prototype system based on the Web. The proposed system supports the spatial search and statistical analysis based on map as well as keyword search, because having the location information on disaster victims, damage occurrence places, welfare and medical institutions, and psychological supporting centers. In addition, this system has the advantage reducing the frequency of disaster damage by providing aids in making efficient policy systems for the managers.
Recently, most enterprises are having a knowlege management boom. A number of books associated with the knowlege management are being published, countless public seminars are held, and many research councils have been organized studying it formally or informally as if not importing the system is like falling behind a fashion. However, there are not many cases that achieved success by constructing the system of knowledge management. Then, why the knowledge management is not so much effective despite so many voices wanting the change of management system and a lot of public lectures about it? I guess the reason is that most companies do not have concrete methodology. Seeing a result of a survey which reported that with spread of venture boom and successful examples being known widely, the outflow of precious human resources is accelerated and a large number of employees of conglomerates have already resigned or are considering separation from their positions, we can realize that are occurring a change which can be nearly called severance in an occupational view and an organization culture. The preference to a large enterprise or a public institution of labor is low today and the notion about a lifelong job is regarded as past remains. As for this, it could be said that the social atmosphere that pursued the stability of a job has been changed to the practical one that attaches importance to ability and pay. The way of thinking of employees has been changed while established organizations cannot satisfy their desire and this explains why important members of a company are flown out. The reason why superior human resources move to venture businesses is that they can do their likable work and also prove their ability as well as unconventional rewards. Although existing companies are trying to preserve important human resources through performance compensating stock option, temporary patching up of personnel management cannot retard the rushing wind of foundation and the outflow of labor. On the contrary, clumsy import of performance-based reward system not only fails to hire superior labor power but also can bring about a sense of incompatibility and conflicts among the remaining employees. Therefore, this thesis, focusing on how to choose, develop, and maintain the human resources, will suggest a future-aiming human resources management model of Korean enterprises after comparing and analyzing the actual condition of domestic companies and the trends of advanced corportaions.
In this study, we monitored the raw materials in home-meal replacement (HMR) products, which have shown more than 63% growth in market size for two years. A total of 89 HMR products were purchased and the DNA barcodes of 112 raw materials in the product samples were analyzed. In order to identify the raw material species, a primer set specific for the 16S ribosomal RNA region of each raw material species was amplified. The amplicon was purified and sequenced, and then used to perform a BLAST search provided by the National Institutes of Health (NIH). The species of the raw material was determined by comparing the nucleotide sequences of the species registered in GenBank with identity and match score. Twenty-four species and three genera were identified from 112 raw materials. Three genera were identified at the genus level because a large number of species belonging to the same genus exist within 98% of the identity criteria. The results of the determination were compared with the available raw materials suggested in the Korea Food Code to determine the Korean name and availability of the foods. Six non-listed species were determined to be edible according to information provided by influential domestic and foreign organizations.
Lee, Hyochul;Ahn, Jihyun;Lee, Kyungeun;Kim, Haesoo;Hong, Changhyung;Oh, Kangsup;Hong, Jin Pyo
Anxiety and mood
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v.13
no.2
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pp.74-85
/
2017
Objective : A variety of approaches are needed to solve high suicide rates in Korean society. Although suicide prevention education has been provided for the public and suicide risk groups in Korea, a systematic discussion of simple, effective suicide prevention guidelines for the general public has yet to be made. Self-help guidelines for suicide prevention, which can help prevent suicide in at risk individuals, will be developed through expert questionnaires. Methods : In order to develop the draft guidelines, suicide prevention self-help phrases were gathered and compiled from homepages and publicity materials of domestic and international suicide prevention and related organizations. A panel of 16 suicide prevention experts conducted primary and secondary surveys using the Delphi method, which derives results from consensus among expert groups. The validity and appropriateness of the guidelines was analyzed using content validity ratios (CVR). Results : Of 33 candidate phrases selected for the suicide prevention guidelines, 9 showed high CVR after the secondary Delphi round. The highest level of support with total agreement was given to 'Do not be alone, stay with someone'. However, more than half of the panelists evaluated 14/27 of the primary Delphi round and 12/26 of the secondary Delphi round phrases as invalid. The researchers completed 10 self-help guidelines for suicide prevention, after eliminating 1 redundant phrase and including 2 additional phrases that showed relatively high CVR. Conclusion : We have developed 10 self-help guidelines for suicide prevention through the consensus of experts. Further studies on the effects of the guidleines relative to suicide rates are needed after widespread dissemination.
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