• Journal of Digital Convergence
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• v.13 no.9
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• pp.21-28
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• 2015

This study shows what the political distrust of three nations was preserved among US, Japan, and South Korea in 2008. According to the World Value Survey research, the political distrust of three nations was reached over 70% when on the basis of national people's consciousness in 2008. Especially in the case of South Korea, the percentage of extreme distrust was the highest compared to the other countries. The reason why South Korea could not manage the nation people's political voice to the government and National Assembly. So consequently political complaining behavior channel should be erected more in the political mechanism. And Korean political parties could not manage the social development and national consolidation. Moreover, attacted the negative effects to society. Political distrust is the worst obstacle in democracy that it will be needed the national consensus to amend it.

• Health Policy and Management
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• v.22 no.4
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• pp.538-560
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• 2012

This study tried to find out the level of national health expenditure and associated factors in the OECD countries and then to derive lessons for Korea's health financing based on the cross-national comparison. As a result, Korea's health expenditure in 2010(7.1% of GDP) accounted for 74.7 percent of the OECD average and ranked as countries to spend less on health. At the same time, the socio-economic indicators such as GDP per capita, elderly population ratio and the total tax revenue to GDP also remained between 72 ~ 82 percent of the OECD average. The public share of health financing(58.2%) was relatively lower than those of other countries. However the health expenditure and the public share have grown 1.9 ~ 2.4 times higher than the OECD average over the past decade. According to the quantitative analysis, countries with relatively high income and elderly population turned out to have high health expenditure. Whereas, an inverse relationship was found between the total health expenditure and the public funding. It was estimated that the value of national health expenditure to GDP decreases 0.083 when the rate of public funding increases 1 percent point. Further, the share of public funding was affected positively by the total tax burden. Based on these findings, this study suggests that the sustainable spending on health and alleviating households' direct burden could be ensured by enhancing the share of public funding along with adjusting the tax burden of the people.

• Molecules and Cells
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• v.44 no.10
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• pp.758-769
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• 2021

Calcium homeostasis modulator 1 (CALHM1) is a membrane protein with four transmembrane helices that form an octameric ion channel with voltage-dependent activation. There are four conserved cysteine (Cys) residues in the extracellular domain that form two intramolecular disulfide bonds. We investigated the roles of C42-C127 and C44-C161 in human CALHM1 channel biogenesis and the ionic current (I_CALHM1). Replacing Cys with Ser or Ala abolished the membrane trafficking as well as I_CALHM1. Immunoblotting analysis revealed dithiothreitol-sensitive multimeric CALHM1, which was markedly reduced in C44S and C161S, but preserved in C42S and C127S. The mixed expression of C42S and wild-type did not show a dominant-negative effect. While the heteromeric assembly of CALHM1 and CALHM3 formed active ion channels, the co-expression of C42S and CALHM3 did not produce functional channels. Despite the critical structural role of the extracellular cysteine residues, a treatment with the membrane-impermeable reducing agent tris(2-carboxyethyl) phosphine (TCEP, 2 mM) did not affect I_CALHM1 for up to 30 min. Interestingly, incubation with TCEP (2 mM) for 2-6 h reduced both I_CALHM1 and the surface expression of CALHM1 in a time-dependent manner. We propose that the intramolecular disulfide bonds are essential for folding, oligomerization, trafficking and maintenance of CALHM1 in the plasma membrane, but dispensable for the voltage-dependent activation once expressed on the plasma membrane.

• Journal of Mushroom
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• v.20 no.2
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• pp.43-49
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• 2022

Pleurotus ostreatus is a globally cultivated mushroom crop. Cap color is a quality factor in P. ostreatus. However, cap color can spontaneously mutate, degrading the quality of the mushroom on the market. Early detection and removal of mutant strains is the best way to maintain the commercial value of the crop. To detect the cap color mutant Gonji7ho, molecular markers were developed based on insertion/deletions (InDels) derived from the comparison of mitogenomes of Gonji7ho and Gonji7hoM mushrooms. Sequencing, assembly, and comparative analysis of the two mitogenomes revealed genome sizes of 73,212 bp and 72,576 bp with 61 and 57 genes or open reading frames (ORFs) in P. ostreatus Gonji7ho and Gonji7hoM, respectively. Fourteen core protein-encoding genes, two rRNA, and 24 tRNA with some OFRs were predicted. Of the 61 genes or OFRs in the wild type, dpo, rpo, and two orf139 were missing (or remnant) in the mutant strain. Molecular markers were developed based on the sequence variations (InDels) between the two mitogenomes. Six polymorphic molecular markers could detect the mutated mitochondria by PCR. These results provide basic knowledge of the mitogenomes of wild-type and mutant P. ostreatus, and can be applied to discriminate mutated mitochondria.

• The Journal of Internal Korean Medicine
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• v.41 no.6
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• pp.933-946
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• 2020

Objective: The aim of this study was to provide a systematic review of the Korean literature on the influence of herbal medicine on liver function. Additionally, we tried to estimate the change in the data on liver function tests (LFTs) and the incidence of liver injury (LI) after taking herbal medicine. Methods: Systematic literature searches were performed on 6 major Korean databases (Research Information Sharing Service (RISS), Korea Institute of Science and Technology information (KISTI), National Assembly Electronic Library, Korean Medical database (KMBASE), Korean Traditional Portal, and Dongui University Electronic Library) from January 2010 to June 2020. No restrictions were placed on the types of publications, which included grey literature. Results: The data indicate that herbal medicine might be a minor cause of LI in Korea. However the results are not supported strongly enough to verify the safety issues because of the limitations of the original studies. Conclusions: Additional well-planned studies are still needed that can overcome the heterogeneity and the considerable methodological flaws in the analyzed studies.

• Korean Journal of Legislative Studies
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• v.15 no.1
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• pp.261-290
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• 2009

The primary purpose of this study is to explain the changing nature of Korean Democratic Labor Party, namely the revealed characteristics contrary to the party's original identity, based on empirical framework of so-called "Korean Democratic Labor Party' as a Parliamentary Party". This paper focuses on the unanticipated phenomenon that Korean Democratic Labor Party, in spite of its expectancy as an alternative party model to overcome the challenges of Korean party politics, has lost its characteristics as a mass party but has revealed the characteristics of parliamentary party since it took parliamentary seats in National Assembly.

• Journal of Family Resource Management and Policy Review
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• v.9 no.3
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• pp.45-68
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• 2005

The political activity of women is relatively low. This is mainly because of the social-cultural attitude that confines women's role to housewives, rather than the structural problems that are related to political activities itself. This study has attempted to enhance the political activities of women by examining and providing the practical informations related to the hardships that are experienced by women who are pursuing a career both as a politician as well as a housewife. The sample of this study consisted of women who are assuming chief executives positions in organizations that are related to political activity, including local representatives of the national assembly. A case study was conducted by interviewing 8 female politicians. The contents of the study mostly consists of the personal situations (related to house lives) of these women. Semi-structured questionnaires were used, and the interview was conducted several times. First, the political careers of these women tended to start passively, rather than voluntarily. Second, the negative attitudes that were initially displayed by the family members and close relatives had changed positively through out the course of time. Close relatives, parents/parents-in-law were likely to become helpers of child care and household labor. The husband was likely to be a supporter of the wife's political career, and the children started to understand the roles of their mother as they grew up. Third, the female politicians perceived that the main impediments of women pursuing political careers were the sexually discriminating culture, rather than their own ability. Fourth, the fact that these women had to spend a lot of time outside the house has worsened the role conflict and difficulties of these women who are required to assume dual-roles. Furthermore, the difficulties that are faced publicly and privately has increased the psychological burdens of these women, since politicians, in general, are people who need to maintain their public image.

• Korean Chemical Engineering Research
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• v.52 no.6
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• pp.695-700
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• 2014

Proton Exchange Membrane Fuel Cells (PEMFC) can generate hydrogen and oxygen from water by electrolysis. But the electrode and polymer electrolyte membrane degrade rapidly during PEM water electrolysis because of high operation voltage over 1.7V. In order to reduce the rate of anode electrode degradation, unsupported $IrO_2$ catalyst was used generally. In this study, Pt/C catalyst for PEMFC was used as a water electrolysis catalyst, and then the degradation of catalyst and membrane were analysed. After water electrolysis reaction in the voltage range from 1.8V to 2.0V, I-V curves, impedance spectra, cyclic voltammograms and linear sweep voltammetry (LSV) were measured at PEMFC operation condition. The degradation rate of electrode and membrane increased as the voltage of water electrolysis increased. The hydrogen yield was 88 % during water electrolysis for 1 min at 2.0V, the performance at 0.6V decreased to 49% due to degradation of membrane and electrode assembly.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.125-125
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• 2017

The roots of Platycodon grandiflorum are commonly used for treating bronchitis, asthma, tuberculosis, diabetes, and other inflammatory diseases. Since the molecular mechanism underlying the roots of the plant is unclear. Therefore, the present study was conducted to profile proteins from liquid cultured tetraploid roots of Platycodon grandi orum fl using high throughput proteome approach. Two-dimensional gels stained with CBB, a total of 659 differentially expressed proteins were identified from the liquid medium cultured tetraploid roots of which 32 proteins spots (${\geq}1.5-fold$) were sorted for mass spectrometry analysis. Out of these 32 proteins, a total of 15 proteins were up-regulated such as Serine carboxypeptidase-like 27, Transcription factor bHLH150, 60 kDa jasmonate-induced protein, Cytosolic Fe-S cluster assembly factor NBP35, Regulatory associated protein of TOR 2 and a total of 17 proteins were down-regulated such as Protein G1-like2, Phenylalanine ammonia-lyase, Fructokinase-2, Trihelix transcription factor GT-3a, Guanine nucleotide-binding protein alpha-1 subunit. However, the frequency distribution of identified proteins was carried out within functional categories based on molecular functions, cellular components, and biological processes. Functional categorization revealed that the most of the identified proteins from the explants were mainly associated with the nucleic acid binding, oxidoreductase, transferase activity, protein binding and hydrolase activity. In addition, the proteomic feedback of tetraploid roots of P. grandiflorum may potentially be used to understand the characteristics of proteins and their functions.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.121-121
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• 2011

Thanks to KMTNet's wide field of view, it is time to implement imaging survey of extensive area of clusters of galaxies in the southern sky with modern instrument. As part of potential long-term survey of nearby (D < 50 Mpc) well-known clusters of galaxies, we propose a wide-field and deep survey of Fornax cluster as a first step of the project. By imaging the 400 square deg region (100 fields) enclosed within the five times virial radius of the Fornax cluster, in three SDSSfilters(g', r', i'), we can provide an unprecedented view of structure of Fornax cluster using sample from giant to dwarf galaxies. We will secure galaxies with brightness comparable to the limiting magnitude (r'=23.1 AB mag) of SDSS. Furthermore, we also request extremely deep (limiting surface brightness of ~ 28 mag $arcsec^{-2}$forr'band) survey for the central region (16 square degree, i.e., four fields) of Fornax cluster. This will allow us to detect the diffuse intracluster light (ICL) that permeates clusters as a valuable tool for studying the hierarchical nature of cluster assembly. In order to complete whole survey, about 285 hr observing time (without overhead) is required. By combining data available at other wavelengths, it will offer unique constraints on the formation of large-scale structure and also provide important clues for theories of galaxy formation and evolution. Our proposed survey will be implemented in the close collaboration with researchers in various countries (Germany, Australia, UK, USA) and ongoing project (e.g., SkyMapper).