• Journal of Ginseng Research
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• v.46 no.3
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• pp.331-336
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• 2022

Coronavirus disease 2019 (COVID-19) exhibits various symptoms, ranging from asymptomatic to severe pneumonia or death. The major features of patients in severe COVID-19 are the dysregulation of cytokine secretion, pneumonia, and acute lung injury. Consequently, it leads to acute respiratory distress syndrome, disseminated intravascular coagulation, multiple organ failure, and death. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of COVID-19, influences nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3 (NLRP3), the sensor of inflammasomes, directly or indirectly, culminating in the assembly of NLRP3 inflammasome and activation of inflammatory caspases, which induce the inflammatory disruption in severe COVID-19. Accordingly, the target therapeutics for inflammasome has attracted attention as a treatment for COVID-19. Korean Red Ginseng (KRG) inhibits several inflammatory responses, including the NLRP3 inflammasome signaling. This review discusses the role of KRG in the treatment and prevention of COVID-19 based on its anti-NLRP3 inflammasome efficacy.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.05a
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• pp.209-212
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• 2013

The Nuri process of emphasis by the Ministry of Education to promote is standardized curriculum at the national level for the education and care. It is to improve the quality of pre-school education and Ensure a fair starting line early in life and It emphasizes character education in all areas of the window. Nuri the process of development of a the insect robot for the Creativity education Increased the interesting and educational effects. Assembly and the effect on learning of educational content using a VR educational robot using the existing floor assembly using the online website to help assemble and learning raised. Order to take advantage of information technology in the information-based society requires the active interest and motivation in learning, creative learning toddlers learning robot are also needed. A three-dimensional model of the robot, and augmented by linking through the marker, the target marker and the camera relative to the coordinate system of augmented reality, seeking to convert the marker to be used in augmented reality marker patterns within a pre-defined patternto be able to make a decision on what of. The fusion of a smart education through training and reinforcement the educational assembly of the robot in the real world window that is represented by a virtual environment in this paper to present a new form of state-of-the-art smart training, you will want to lay the foundation of the nation through the early national talent nurturing talent.

• Journal of Internet Computing and Services
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• v.17 no.3
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• pp.33-43
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• 2016

In this study, 3D-image based course material has been suggested as a potential pedagogical tool for laboratory courses for aviational maintenance in vocational high schools. With a special focus on assembly/disassembly of the combustion chamber, 3D contents described here are created by Soildworks 2014 based on the textbook widely used in aviational high schools. By analyzing several textbooks currently adopted at various schools, we have clearly shown that the current text-based teaching method is far from being effective regarding providing adequate learning environment for high school students who study aviational maintenance. From the analysis of the conventional textbooks, it is seen that it is urgent that we should come up with more effective and efficient way of teaching methods for these topics at vocational high schools. Using Solidworks, we have developed very vivid 3D image-based course material for topics related to a combustion chamber in the airplane. Newly developed 3D material is seen to clearly show step by step procedures of assembly and disassembly of the combustion chamber which has crucial importance in the aviational laboratory courses. Especially the transparent feature in Solidworks could make it possible to observe the parts covered by outer casing, which can not be seen even in any laboratory class with real objects. 3D animated views could provided unprecedented learning environment for students to acquire core knowledge with ease for the maintenance of a combustion chamber. In order to provide easy access for students to this 3D-based course material, the exclusive viewer is also developed using MS office powerpoint 2007. An example of a learning plan using 3d course material is suggested as well.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.41 no.5
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• pp.551-557
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• 2021

Attached parking lots installation criteria is determined by use, total floor area, etc. according to the Parking Lot Act and local government ordinances. However, with traffic demand increase inconvenience about use of culture and assembly facilities have been raised. When planning number of parking lots for cultural and assembly facilities, legal parking lots and unit parking lots are used, but this causes inconvenience and traffic problems on the surrounding roads, because reality and convenience are not considered. Therefore, this study intend to present an realistic number of parking lots calculating equation for movie theater in Gwangju Metropolitan City. After investigating number of parking lots, number of screens, number of seats, total floor area, bus route and illegal parking for a cultural facility in Gwangju Metropolitan City, prediction model for calculating number of parking lots was presented using SPSS regression analysis. As a result of comparing prediction model and unit method, the prediction model was be closer actual cumulative parking space, so prediction model verification was completed. Based on the model verified in this study, Realistic number of parking lots will be installed. However, due to limitations of research on specific areas, research on various facilities should continue in consideration of regional, population, and urban characteristics

• Korean Journal of Health Education and Promotion
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• v.27 no.2
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• pp.1-15
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• 2010

Objectives: The purpose of this study was to examine the past and present status and roles of health education specialists in Korea, and to suggest future directions for developing health education profession. Results and conclusion: The Korean government has made various efforts for people's health. the National Health Promotion Law was enacted in Korea in 1995. As the results of Korean Association for Health Education' intensive efforts, the national certificate of health education specialist bill has been passed the National Assembly on September 29, 2003. According to The National Health Promotion Law, central and local government should recommend health promotion related corporaters, agencies and organizations to hire certified health education specialist. The first national examination for certificate of health education specialists was held in March, 2010. As the result, a total of 2,246 applicants was passed for certificate of health education specialists. It is a serious concern that community residents' knowledge level of health is very low. therefore, the role of health education specialists with the professional ability to carry out health education is essential. It is clear that the activity of health educators is essential, Then, It is necessary articles related to the appointment of health educators in the official appointment regulation or law. Thus the health education specialist must be appointed as a public officer in health centers, operaters or the health department of the government.

• Journal of Microbiology and Biotechnology
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• v.19 no.5
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• pp.502-510
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• 2009

Although the Escherichia coli heat-labile enterotoxin B subunit (LTB) has already been expressed in several different systems, including prokaryotic and eukaryotic organisms, studies regarding the synthesis of LTB into oligomeric structures of pentameric size in the budding yeast Saccharomyces cerevisiae have been limited. Therefore, this study used a functional signal peptide of the amylase 1A protein from rice to direct the yeast-expressed LTB towards the endoplasmci reticulum to oligomerize with the expected pentameric size. The expression and assembly of the recombinant LTB were confirmed in both the cell-free extract and culture media of the recombinant strain using a Western blot analysis. The binding of the LTB pentamers to intestinal epithelial cell membrane glycolipid receptors was further verified using a GM1-ganglioside enzyme-linked inmmunosorbent assay (GM1-ELISA). On the basis of the GM1-ELISA results, pentameric LTB proteins comprised approximately 0.5-2.0% of the total soluble proteins, and the maximum quantity of secreted LTB was estimated to be 3 mg/l after a 3-day cultivation period. Consequently, the synthesis of LTB monomers and their assembly into biologically active aligomers in a recombinant S. cerevisiae strain demonstrated the feasibility of using a GRAS microorganism-based adjuvant, as well as the development of carriers against mucosal disease.

• Journal of the Korean Electrochemical Society
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• v.15 no.2
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• pp.109-114
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• 2012

The cathode catalyst layer in polymer electrolyte membrane fuel cells (PEMFCs) was fabricated with anodic aluminum oxide (AAO) template and its structure was characterized with scanning electron microscopy (SEM) and Brunauer-Emmett-Teller (BET) analysis. The SEM analysis showed that the catalyst layer was fabricated the Pt nanowire with uniform shape and size. The BET analysis showed that the volume of pores in range of 20-100 nm was enhanced by AAO template. The electrochemical properties with the membrane electrode assembly (MEA) were evaluated by current-voltage polarization measurements and electrochemical impedance spectroscopy. The results showed that the MEA with AAO template reduced the mass transfer resistance and improved the cell performance by approximately 25% through controlling the structure of catalyst layer.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.2
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• pp.47.1-47.1
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• 2015

The formation mechanism of supermassive black holes (SMBHs) at the center of galaxies remains an open fundamental question. Black holes (BHs) are believed to grow by accretion of gas or by merging with other BHs. Motivated by the observation of luminous quasar around redshift z ~ 7 with SMBH mass up to 109 solar mass, we follow the growth of the early assembly of SMBHs that trace the hierarchical evolution of dark matter halos derived from large cosmological simulations. The initial masses of BH seeds in the first halos were set up according to the BH mass - halo mass relation. We assume that mergers of host galaxies cause loss of angular momentum of gas and trigger episodes of gas accretion onto BHs for available durations and at the end of each episode of accretion, BHs merge immediately. We trace the evolution of BH masses for various scenarios for central gas properties in halos. We estimate the BH to halo mass ratio and BH mass function at each redshift.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.6
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• pp.44-49
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• 2007

It is well known that the acoustic cavity inside the tire-wheel assembly contributes to vehicle interior noise. In this paper, we have performed acoustic and structural modal testings to investigate the influences of the acoustic cavity resonance on structural vibration characteristics for the tire in free-suspension and for the loaded tire. The testings have given us some findings, which are reported in this paper.

• Journal of Korean Society for Quality Management
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• v.33 no.4
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• pp.88-95
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• 2005

Multistage screening is a common practice when a component has a critical effect on the function of the assembly. A defect in a component might incur malfunction of an electronic device, resulting in a great amount of loss. Multistage screening, including duplicated screening inspections, may provide a good solution for this problem when inspection errors are present. In the company studied here, the manufacturing process of the multiple layer chip capacitor includes two-stage screening. In the first stage, screening inspection is performed repeatedly until no defects are found in the lot. In the second stage, sampling inspection is performed by a group of experts prior to shipment. In this article, we review the procedure used in the field and suggest a revised model of the multiple screening procedure and solution method for this situation. The usefulness of the proposed model is discussed through a practical example.