• Title/Summary/Keyword: Korea Science and Engineering Foundation

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Purification and Characterization of the Extracellular Alginase Produced by Bacillus licheniformis AL-577 (알긴산 분해균 Bacillus licheniformis AL-577가 생산하는 균체외 효소의 정제 및 특성)

  • Uo, Meung-Hee;Joo, Dong-Sik;Cho, Soon-Yeong;Min, Tae-Sun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.2
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    • pp.231-237
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    • 2006
  • The extracellular enzyme alginase produced by Bacillus licheniformis AL-577 was purified by ion chromatography on CM-Cellulose column, DEAE-Sepharose column, and followed by gel filtration on Sephadx G-100 column. The optimum pH and temperature for the activity of the purified enzyme were 6.0 and $35^{\circ}C$, respectively. The enzyme was stable at the pH range of $6.0\~9.0$ and at $20^{\circ}C$. The molecular weight of the enzyme was estimated to be about 25,500 daltons by SDS-polyacrylamide gel electrophoresis. NaCl was required for high activity of the enzyme. The enzyme was inhibited by $Ba^{2+},\;Co^{2+},\;Cu^{2+},\;Fe^{2+},\;Mg^{2+},\;Zn^{2+},\;NH_4^+$, EDTA, L-cysteine, and 2-mercaptoethanol, while stimulated by DTT, O-phenanthroline, $K^+$ and $Li^+$. This enzyme was proposed to be an alginase specifically degrading alginic acid.

A Study on the Cultural and Technical Influence Factor Using Unstructured Data Analysis (비정형 데이터 분석을 이용한 수원 화성의 문화·기술적 영향요인 연구)

  • Park, Eun Soo;Kim, Ji Eun
    • Korea Science and Art Forum
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    • v.20
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    • pp.227-241
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    • 2015
  • As time is rapidly changing, the culture to represent an era is getting more subdivided and complex. Due to cultural diversity, the influence, cause, characteristics which could be understood in individual field centered by space in the past cannot be understood now only by the viewpoint of one field, and it has become difficult to predict and correspond to the change of the future. With the development of information and knowledge delivery system, various cultural contents to form a space are being created and lapsed, but there are a lot of parts which cannot be explained or understood by only one point of view. To inspect these situation, this study is aimed to draw the cultural and technical causes that became the influence with Suwon Hwaseong, a traditional space with historical superiority, analyze the key factors that became the main factor to form the space, and consider the importance of the related factors. Suwon Hwaseong is a new town formed by the order of King Jeongjo. Suwon Hwaseong at that time was a space with the will and effort of many people who dreamed a new era, and it has a meaning of varoius time ans space as historical facts and cultural values as well as the progress and development of scientific technology. The unstructured data technique which is applied as the method of analysis in this study can be said to be a new value judgement and viewpoint in interpreting the space. Therefore, this study is a new trial to provide a frame for multilaterally interpreting the various traditional space and culture of Korea from the past to the present.

Induction of Demyelination of Neuronal cells by Sindbis Virus (Sindbis Virus에 의한 뉴런세포의 탈수초의 유도)

  • Sa, Young-Hee;Kim, Hyun Joo;Kweon, Tae Dong;Kim, Ji-Young;Lee, Bae Hwan;Hong, Seong-Karp
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.584-587
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    • 2018
  • Many viruses including mouse hepatitis virus, corona, measles, and sidbis viruses are known as causative virus of inducing demyelination which means destruction of myelination in nervous system of mice. The purpose of this study is to investigate processing of myelination by co-culture of Schwann cells and neuronal cells and demyelination induced by infection of sindbis virusin rat. Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos (E16) of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured. After that, infection of sindbis virus into this myelinated co-culture system was performed. Myelination and demyelination process were observed using antibody of myelin basic protein meaning presence of myelination.We identified myelination and demyelination processing using antibody of peripheral myelin protein 22 (PMP 22) meaning presence of myelinated neuron. This study was supported by the Basic Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2015R1C1A1A01053484 and 2017R1A2B3005753).

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Development and Effectiveness of STEAM Outreach Program based on Mathematics (수학을 기반으로 하는 STEAM 아웃리치 프로그램 개발과 효과성)

  • Hwang, Sunwook;Kim, Namjun;Son, Jeongsuk;Song, Wonhee;Lee, Kapjung;Choi, Seongja;Lew, Kyounghoon
    • Communications of Mathematical Education
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    • v.31 no.4
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    • pp.389-407
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    • 2017
  • Many researches related to STEAM education have been actively conducted for developing elementary and secondary school students' comprehensive and logical thinking ability in relation to creativity education in Korea. Each sub factor of STEAM education requires creative thinking with the ability to be merged together to solve problems as integrated or combined forms in the fields of Science, Technology, Engineering, Arts, and Mathematics. Also, these STEAM activities and experiences should be carried out at various places outside the classroom in school. Although various educational programs to enhance mathematical creativity have been emphasized for elementary and secondary school students, recent tendency to focus on classroom learning in the school makes it difficult to develop creative thinking ability of students. This research is mainly based on the result of the project "Development and Administration of STEAM Outreach Program in 2016" supported by KOFAC(Korea Foundation for the Achievement of Science & Creativity). The purpose of this research is to develop a STEAM outreach program including students' activity books, teachers' manuals and administration manual that can maximize STEAM-related interest of students, and to provide a chance for elementary and secondary school students to experience creative thinking based on sub factors of STEAM. The STEAM competency total score and the perception of convergence education were significantly increased for all students participating this program, but some sub factors showed different result by school levels. The STEAM outreach program developed by this study is designed to emphasize STEAM education especially 'based on' mathematics in order to provide students with the opportunity to experience more interest in the field of mathematics and will be able to provide an interesting creative STEAM outreach program that utilizes a variety of activities which, we expect, would help students to consider their career in the future.

A Study on the Tangibility and Intangibility Value Contents Influence Factor of Jongmyo Shrine Using Text Mining Analysis (텍스트 마이닝 분석을 활용한 종묘의 유·무형 콘텐츠 영향요인 연구)

  • Park, Eun Soo;Kim, Ji Eun
    • Korea Science and Art Forum
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    • v.22
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    • pp.169-183
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    • 2015
  • As time is rapidly changing, the culture to represent an era is getting more subdivided and complex. Due to cultural diversity, the influence, cause, characteristics which could be understood in individual field centered by space in the past cannot be understood now only by the viewpoint of one field, and it has become difficult to predict and correspond to the change of the future. With the development of information and knowledge delivery system, various cultural contents to form a space are being created and lapsed, but there are a lot of parts which cannot be explained or understood by only one point of view. To inspect these situation, this study is aimed to draw the Tangibility and Intangibility Value causes that became the influence with Jongmyo Shrine, designated from UNESCO at February 1995, a traditional space with historical superiority, analyze the key factors that became the main factor to form the space, and consider the importance of the related factors. The unconstructured data technique which is applied as the method of analysis in this study can be said to be a new value judgement and viewpoint in interpreting the space. Therefore, this study is a new trial to provide a frame for multilaterally interpreting the various traditional space and culture of Korea from the past to the present.

Oxidation of Phenol Using Ozone-containing Microbubbles Formed by Electrostatic Spray (전기장에 의해 생성된 미세기포를 이용한 페놀의 오존산화)

  • Shin, Won-Tae;Jung, Yoo-Jin;Sung, Nak-Chang
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.12
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    • pp.1292-1297
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    • 2005
  • The use of ozone in water and wastewater treatment systems has been known to be a process that is limited by mass transfer. The most effective way to overcome this limitation is to increase the interfacial area available for mass transfer by decreasing the size of the ozone gas bubbles that are dispersed in solution. Electrostatic spraying(ES) of ozone into water was investigated in this work as a method of increasing the rate of mass transfer of ozone into a solution and thereby increasing the rate of phenol oxidation. Results were obtained for ES at input power levels ranging from 0 to 4 kV and compared with two different pore-size bubble diffusers($10{\sim}15{\mu}m$ and $40{\sim}60{\mu}m$). It was determined that the rate of mass transfer could be increased by as much as 40% when the applied voltage was increased from 0 to 4 kV as a result of the smaller bubbles generated by ES. In addition, ES was shown to be more effective than the medium-pore-size($10{\sim}15{\mu}m$) bubble diffuser and the best results were achieved at low gas flow rates.

Design and Implementation of File Cloud Server by Using JAVA SDK (Java SDK를 이용한 파일 클라우드 시스템의 설계 및 구현)

  • Lee, Samuel Sangkon
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.8 no.2
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    • pp.86-100
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    • 2015
  • Cloud computing is a computing term that evolved in the late 2000s, based on utility and consumption of computer resources. Google say that "Cloud computing involves deploying groups of remote servers and software networks that allow different kinds of data sources be uploaded for real time processing to generate computing results without the need to store processed data on the cloud. Cloud computing relies on sharing of resources to achieve coherence and economies of scale, similar to a utility (like the electricity grid) over a network. At the foundation of cloud computing is the broader concept of converged infrastructure and shared services. Cloud computing, or in simpler shorthand just "the cloud", also focuses on maximizing the effectiveness of the shared resources." The cloud service is a smart and/or intelligent service to save private files in any device, anytime, anywhere. Dropbox, OAuth, PAClous are required that the accumulated user's data are archives with cloud service. Currently we suggest an implementation technique to process many tasks to the cloud server with a thread pooling. Thread pooling is one of efficient implementating technique for client and service environment. In this paper, to present the implementation technique we suggest three diagrams in the consideration of software engineering.

A Study on the Difference of Geometrical Modeling in the Calculation of Shielding and Activation Using Monte Carlo Simulation (몬테카를로 시뮬레이션을 이용한 차폐 및 방사화 계산에서 기하학적 모델링의 차이에 따른 결과 연구)

  • Heo, Seunguk;Song, Yongkeun;Cho, Gyuseok;Han, Moojae;Park, Jikoon
    • Journal of the Korean Society of Radiology
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    • v.11 no.6
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    • pp.429-435
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    • 2017
  • In order to increase the therapeutic effect of radiation, there has been an increase in the use of conventional photon therapy. The intensive care unit should pay more attention to the radiation safety evaluation due to the higher energy and the larger facility compared to the existing Photon treatment. These radiation safety evaluations are mainly performed by using Monte Carlo simulation, and the first thing to be done is geometric modeling. The Heavy-ion treatment facility uses synchrotron as the accelerating device, which is difficult to precisely model geometrically and is mostly modeled briefly. This study investigated the effect of simplification and precise implementation of Dipole magnet among the components of synchrotron acceleration device on the radiation safety evaluation. The results show that the simplified geometric model is overestimated with the precisely implemented geometric model. Therefore, it is considered that the radiological safety evaluation results in more reliable results of the precise geometric modeling.

Increased Water Resistance and Adhesion Force to Skin through the Hybrid of Fatty Acid Ester and Titanium Dioxide (지방산 에스테르와 티타늄다이옥사이드의 복합화를 통한 내수성과 피부 밀착력 개선)

  • Ji Yeon Hong;Chi Je Park;Yong Woo Kim;Sang Keun Han;Sung Bong Kye;Ho Sik Roh;Soo Nam Park
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.3
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    • pp.247-258
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    • 2023
  • This study aims to investigate the enhancement of water resistance and improvement in adhesion to the skin by combining dextrin palmitate and isopropyl titanium triisostearate coating materials with titanium dioxide. Due to the recent increase in consumers who enjoy outdoor activities, the demand for sunscreen with excellent water resistance is increasing. Prior research was conducted with O/W, Pickering, and W/O/W multiple formulations, but there was a limit to water resistance. The purpose of this study is to develop a complex inorganic powder that can improve water resistance and increase adhesion to the skin to solve this problem. First, we combined dextrin palmitate and isopropyl titanium triisostearate coating materials to form a composite with titanium dioxide. The coating of the inorganic powder was confirmed using FE-SEM and FT-IR analysis. The composite exhibited significantly higher in vitro water resistance compared to other formulations. The hydrophobicity of the coated inorganic powder was compared by measuring the contact angles. When the coated inorganic powder was applied to the W/O sunscreen formulation and the non-coated inorganic powder was applied to the W/O sunscreen formulation as a control, the SPF of the sunscreen containing the coated inorganic powder was higher. These results were the same when observed with a UV camera. Finally the adhesion of the coated inorganic powder to the skin was assessed by applying it to a foundation product. In vivo study, it was observed that the product formulated with the coated powder exhibited less smudging compared to the foundation product formulated with the non-coated powder. The developed inorganic powder in this study demonstrated excellent adhesion to the skin, providing a superior sensory experience, as well as enhanced hydrophobicity and remarkable water resistance effects. In the future, the result of this study is expected to help develop various sunscreen products to improve water resistance.

Simulation of eccentricity effects on short- and long-normal logging measurements using a Fourier-hp-finite-element method (Self-adaptive hp 유한요소법을 이용한 단.장노말 전기검층에서 손데의 편향 효과 수치모델링)

  • Nam, Myung-Jin;Pardo, David;Torres-Verdin, Carlos;Hwang, Se-Ho;Park, Kwon-Gyu;Lee, Chang-Hyun
    • Geophysics and Geophysical Exploration
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    • v.13 no.1
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    • pp.118-127
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    • 2010
  • Resistivity logging instruments are designed to measure the electrical resistivity of a formation, and this can be directly interpreted to provide a water-saturation profile. However, resistivity logs are sensitive to borehole and shoulder-bed effects, which often result in misinterpretation of the results. These effects are emphasised more in the presence of tool eccentricity. For precise interpretation of short- and long-normal logging measurements in the presence of tool eccentricity, we simulate and analyse eccentricity effects by combining the use of a Fourier series expansion in a new system of coordinates with a 2D goal-oriented high-order self-adaptive hp finite-element refinement strategy, where h denotes the element size and p the polynomial order of approximation within each element. The algorithm automatically performs local mesh refinement to construct an optimal grid for the problem under consideration. In addition, the proper combination of h and p refinements produces highly accurate simulations even in the presence of high electrical resistivity contrasts. Numerical results demonstrate that our algorithm provides highly accurate and reliable simulation results. Eccentricity effects are more noticeable when the borehole is large or resistive, or when the formation is highly conductive.