• Asian-Australasian Journal of Animal Sciences
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• 제22권11호
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• pp.1477-1486
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• 2009

Female germ cell meiotic divisions are typically asymmetric, giving rise to two daughter cells with different sizes. Spindle movements including spindle migration from the oocyte center to the cortex and spindle rotation from parallel to perpendicular (typically in the mouse) at the cortex are crucial for these asymmetric divisions and therefore are crucial for gamete production. Different regulatory mechanisms for spindle movements have been determined in different species and a wide variety of different molecular components and processes that are involved in spindle movements have also been identified in different species. Here, we review the current state of knowledge as well as our understanding of mechanisms for spindle movements in different systems with focus on three main aspects: microtubules (MT), microfilaments (MF) and molecules associated with cytoskeletal organization as well as molecules that are not directly related to the cytoskeleton. How they might interact or function independently during female meiotic divisions in different species is discussed in detail.

• Journal of Animal Science and Technology
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• 제58권5호
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• pp.18.1-18.10
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• 2016

Muscle, studied mostly with respect to meat production, represents one of the largest protein reservoirs of the body. As gene expression profiling holds credibility to deal with the increasing demand of food from animal sources, excessive loss due to myopathies and other muscular dystrophies was found detrimental as it aggravates diseases that result in increased morbidity and mortality. Holding key point towards improving the developmental program of muscle in meat producing animals, elucidating the underlying mechanisms of the associated pathways in livestock animals is believed to open up new avenues towards enhancing the lean tissue deposition. To this end, identification of vital candidate genes having no known function in myogenesis, is believed to increase the current understanding of the physiological processes going on in the skeletal muscle tissue. Taking consequences of gene expression changes into account, knowledge of the pathways associated with their activation and as such up-regulation seems critical for the overall muscle homeostasis. Having important implications on livestock production, a thorough understanding of postnatal muscle development seems a timely step to fulfil the growing need of ever increasing populations of the world.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 1998년도 추계학술대회 논문집
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• pp.407-410
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• 1998

Configuration is a set of building block processes, a series of selection and combining parts or components which composes a whole thing. A whole thing could be such a configurable object as manufacturing product, network system, financial portfolio, system development plan, project team, etc. Configuration problem could happen during any phase of product life cycle: design, production, sales, installation, and maintenance. Configuration has long been one of cost and time consuming work, because only high salaried technical experts on product and components can do configuration. Rework for error adjustments of configurations at later process causes far much cost and time, so accurate configuration is required. Under the on-line electronic commerce environment, configuration problem solving becomes more important, because component-based sales should be done automatically on the merchant web site. Automated product search, order placement, order fulfillment and payment make that manual configuration is no longer feasible. Automated configuration means that all the constraints among components should be checked and confirmed by configuration engine automatically. In addition, technical constraints and customer preferences like price range and a specific function required should be considered. This paper gives an brief overview of configuration problems: characteristics, representation paradigms, and solving algorithms and introduce CRSP(Constraint and Rule Satisfaction Problem) method. CRSP method adopts both constraint and rule for configuration domain knowledge representation. A survey and analysis on web sites adopting configuration functions are provided. Future directions of configuration for EC is discussed in the three aspects: methodology itself, companies adopting configuration function, and electronic commerce industry.

• The Korean Journal of Physiology and Pharmacology
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• 제24권1호
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• pp.1-10
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• 2020

Autophagy is a highly conserved intracellular degradation and energy-recycling mechanism that contributes to the maintenance of cellular homeostasis. Extensive researches over the past decades have defined the role of autophagy innate immune cells. In this review, we describe the current state of knowledge regarding the role of autophagy in neutrophil biology and a picture of molecular mechanism underlying autophagy in neutrophils. Neutrophils are professional phagocytes that comprise the first line of defense against pathogen. Autophagy machineries are highly conserved in neutrophils. Autophagy is not only involved in generalized function of neutrophils such as differentiation in bone marrow but also plays crucial role effector functions of neutrophils such as granule formation, degranulation, neutrophil extracellular traps release, cytokine production, bactericidal activity and controlling inflammation. This review outlines the current understanding of autophagy in neutrophils and provides insight towards identification of novel therapeutics targeting autophagy in neutrophils.

• 한국동물생명공학회지
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• 제35권2호
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• pp.113-118
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• 2020

Hepatic stellate cells (HSCs) play essential roles in normal and pathophysiological function in liver. In steady state, HSCs contribute to retinoid storage, immune tolerance, and extracellular matrix (ECM) homeostasis. Upon liver injury, they become activated and lead to morphological and functional changes. Studies have demonstrated that activation of HSCs by various stimuli such as toxins, microbial infection, or metabolic overload can promote the fibrotic changes in liver by production of ECM. Herein, we provide current knowledge about the basic characteristics of HSCs and the mechanism by which they are activated.

• 한국비블리아학회지
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• 제13권1호
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• pp.43-57
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• 2002

정보와 지식이 생산요소로서 인식되는 지식경영 환경에서 기업이 필요로 하는 많은 지식과 정보를 인터넷에서 쉽고 효과적으로 수집하기 위한 방법을 찾고자 하였다. 연구결과 인터넷에서 일반 검색엔진에 의한 경쟁정보 수집은 매우 부정적으로 나타났다. 이를 대처하기 방안으로 특정사이트를 집중 검색하거나 혹은 맞춤 정보서비스를 받거나 혹은 검색엔진의 제한기능을 활용하는 방법을 제시하였다.

• 한국컴퓨터정보학회논문지
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• 제24권5호
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• pp.11-17
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• 2019

In this study, we propose an ensemble engine, which is a framework for game engine optimized for visual novels genre, focusing on storytelling among various game genres. The game of Visual Nobel genre is based on multi-ending story and features branching of various scenarios according to user's choice. The proposed engine supports various multi-scenarios and multi-endings based on nodes according to the characteristics of these genres. In addition, it provides a convenient and intuitive user interface that not only enhances user immersion but also provides VR function to maximize the sense of presence. We will demonstrate the usefulness of the proposed game engine by designing the framework of a game engine suitable for this feature and actually creating variety stories automatically.

• 반도체디스플레이기술학회지
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• 제20권3호
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• pp.93-96
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• 2021

The desire for a technology that can mechanically acquire 2D images starting with the manual method of drawing has been making possible a wide range of modern image-based technologies and applications over a period. Moreover, this trend of the utilization of image-related technology as well as image-based information is likely to continue. Naturally, as like other technology areas, the function that humans produce and utilize by using images needs to be automated by using computing-based technologies. Surprisingly, technology using images in the future will be able to discover knowledge that humans have never known before through the information-related process that enables new perception, far beyond the scope of use that human has used before. Regarding this trend, the manipulation and configuration of massively distributed image database system is strongly demanded. In this paper, we discuss image identifier production methods based on the utilization of the image hashing technique which especially puts emphasis over an entropy operator.

• 산업경영시스템학회지
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• 제38권4호
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• pp.39-44
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• 2015

The VHTR (Very High Temperature gas-cooled nuclear Reactor) has been considered as a major heat source and the most safe generation IV type reactor for mass hydrogen production to prepare for the hydrogen economy era. The VHTR satisfies goals for the GIF (Generation IV International Forum) policy such as sustainablility, economics, reliability and proliferation resistance and physical protection, and safety. As a part of a VHTR economic analysis, we have studied the VHTR construction cost and operation and maintenance cost. However, it is somewhat difficult to expect the ripple effect on the whole industry due to the lack of information about Inter-industries relationship. In many case, the ripple effect are based on experts' knowledge or uncertain qualitative assumptions. As a result, we propose quantitative analysis techniques for ripple effects such as the production inducement effect, added value inducement effect, and employment inducement effect for VHTR 600MWt${\times}$4 modules construction and operation ripple effect based on NOAK (Nth Of A Kind). Because inducement effect values have been published annually, we predict inducement effect's relation function and estimated values including production inducement effect value, added value inducement effect value, and employment inducement effect value using time series and estimated values are verified with published inducement effects' value. This paper presents a new method for the ripple effect and preliminary ripple effect consequence using a time series analysis and inter-industry table. This ripple effect analysis techniques can be applied to effect expectation analysis as well as other type reactor's ripple effect analysis including VHTR for process heat.

• Advances in robotics research
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• 제2권3호
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• pp.201-217
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• 2018

Agriculture production is a critical human intensive task, which takes place in all regions of the world. The process to grow and harvest crops is labor intensive in many countries due to the lack of automation and advanced technology. Much of the difficult, dangerous and dirty labor of crop production can be automated with intelligent and robotic platforms. We propose an intelligent, agent-oriented robotic team, which can enable the process of harvesting, gathering and collecting crops and fruits, of many types, from agricultural fields. This paper describes a novel robotic organization enabling humans, robots and agents to work together for automation of gathering and collection functions. The focus of the research is a model, called HARMS, which can enable Humans, software Agents, Robots, Machines and Sensors to work together indistinguishably. With this model, any capability-based human-like organization can be conceived and modeled, such as in manufacturing or agriculture. In this research, we model, design and implement a technology application of knowledge-based robot-to-robot and human-to-robot collaboration for an agricultural gathering and collection function. The gathering and collection functions were chosen as they are some of the most labor intensive and least automated processes in the process acquisition of agricultural products. The use of robotic organizations can reduce human labor and increase efficiency allowing people to focus on higher level tasks and minimizing the backbreaking tasks of agricultural production in the future. In this work, the HARMS model was applied to three different robotic instances and an integrated test was completed with satisfactory results that show the basic promise of this research.