• 한국측량학회지
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• 제39권2호
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• pp.113-122
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• 2021

Urban expansion, particularly converting sub-urban areas to residential and commercial land use in metropolitan areas, has been considered as a significant signal of regional economic development. However, this results in urban climate change. One of the key impacts of rapid urbanization on the environment is the effect of UHI (Urban Heat Island). Understanding the effects of urban land cover change on UHI is crucial for improving the ecology and sustainability of cities. This research reports an application of remote sensing data, GIS (Geographic Information Systems) for assessing effects of urban land cover change on the LST (Land Surface Temperature) and heat budget components in Ho Chi Minh City, where is one of the fastest urbanizing region of Vietnam. The change of urban land cover component and LST in the city was derived by using multi-temporal Landsat data for the period of 1998 - 2020. The analysis showed that, from 1998 to 2020 the city had been drastically urbanized into multiple directions, with the urban areas increasing from approximately 125.281 km² in 1998 to 162.6 km² in 2007, and 267.2 km² in 2020, respectively. The results of retrieved LST revealed the radiant temperature for 1998 ranging from 20.2℃ to 31.2℃, while that for 2020 remarkably higher ranging from 22.1℃ to 42.3℃. The results also revealed that given the same percentage of urban land cover components, vegetation area is more effective to reduce the value of LST, meanwhile the impervious surface is the most effective factor to increase the value of the LST.

• 대한한의학회지
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• 제42권3호
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• pp.44-55
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• 2021

Objectives: As the use of herbal medicinal products (HMPs) increases worldwide, systematic verification of the safety of HMPs is required. The induction of cardiotoxicity is one of the major factors in post-approval withdrawal of medicinal products, and drug-induced cardiotoxicity assessment is emerging as an important step in drug development. In the present study, we evaluated human ether-à-go-go-related gene (hERG) potassium channel-related cardiotoxicity to predict the risk of cardiac arrhythmia in thirteen herbal medicines known to have cardiac toxicity. Methods: We measured the inhibition rate of hERG potassium channel activity of 13 medicinal herbal extracts in hERG-expressing HEK 293 cells using an automated patch-clamping system. Quinidine was used as a positive control for inhibition of hERG activity. Results: Extracts of Evodiae Fructus, Strychni Semen, and Corydalis Tuber potently inhibited the activity of hERG, and IC₅₀ values were 3.158, 19.87, and 41.26 ㎍/mL, respectively. Cnidi Fructus, Ephedra Herba, Lithospermi Radix, Polygoni Multiflori Radix, Visci Ramulus et Folium, Asiasari Radix et Rhizoma, and Scolopendra weakly inhibited hERG activity, and the IC₅₀ value for each herbal medicine was more than 400 ㎍/mL. Aconiti Kusnezoffii Tuber and two types of Aconiti Lateralis Radix Preparata (Po and Yeom) had weak inhibitory activity against hERG, and the IC₅₀ values were more than 700 ㎍/mL. The IC₅₀ value of quinidine against hERG was 1.021 𝜇M. Conclusion: Evodiae Fructus, Strychni Semen, and Corydalis Tuber acted as potent inhibitors against hERG. These herbal medicines may cause cardiac arrhythmia through QT prolongation, so care should be taken when taking them.

• 자원환경지질
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• 제23권2호
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• pp.215-219
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• 1990

Geological and electrical resistivity surveys along the survey line of about 3 km between Kyungsangbukdo Youngilgun Hodong and Gwangmyungdong using by dipole-dipole electrode array method were carried out to examine the boundary and structural relationship between Tertiary Pohang and Janggi basins. Electrical resistivity data were interpreted qualitatively and quantitatively by means of pseudosection of apparent electrical resitivity distribution and finite difference method for two dimensional geologic structure model. The nearly vertical fault zone with low electrical resistivity value of 1-5 Ohm-m and widths of about 200m at the surface and 400 m at depth exists around 1.2 km west of national road between Ocheoneup and Yangbukmyun. Mudrocks, sandstones and tuffaceous rocks are widely distributed with electrical resistivity values of 6-77 Ohm-m. Especially, tuffaceous rocks with relatively high electrical resistivity value are predominant at eastern side of fault zone. Consequently, it is known that Pohang and Janggi basins are in fault contact.

• 환경위생공학
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• 제11권2호
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• pp.21-26
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• 1996

In our previous studies, we reported that lead intoxicated nerve cell by inhibition of the Na$^{+}$-K$^{+}$ ATPase activity and reduction of myo-inositol in nerve cell. As the second series of experiments, in order to understand toxic mechanism of lead for nerve cell, the characteristics of myo-inositol transport system and the effect of lead on its system have been studied in the sciatic nerves of control and lead-treated rats. A lead intoxicated animal model was induced by feeding diet containing lead to Sprague-Dawley rat for two weeks. Four weeks aged Sprague-Dawley rats were divided into three group : normal control group, 10ppm-lead treated group, 100ppm-lead treated group. All rats were sacrified at the end of two weeks. The rate o myo-inositol transport by sciatic nerve isolated from lead-treated rat was significantly decreased compared with that of control rat. This deficit results from that myo-inositol transport system which is carrier mediated and sodium-potassium dependent was inhibited by the lead treatment (both 10ppm and 100ppm) due to increase of the Km value without affecting Vmax value for myo-inositol carrier. These observations suggest that the toxic mechanism of lead on nerve myo-inositol transport system might be a change of affinity without change of maximum transport velocity for carrier.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume II
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• pp.655-659
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• 2006

Surface Solar Insolation is important for vegetation productivity, hydrology, crop growth, etc. In this study, Surface Solar Insolation is estimated using Multi-functional Transport Satellite (MTSAT-1R) in clear and cloudy conditions. For the Cloudy sky cases, the surface solar insolation is estimated by taking into account the cloud transmittance and multiple scattering between cloud and surface. This model integrated Kawamura's model and SMAC code computes surface solar insolation with a 5km ${\times}$ 5km spatial resolution in hourly basis. The daily value is derived from the available hourly Surface Solar Insolation, independently for every pixel. To validation, this study uses ground truth data recorded from the pyranometer installed by the Korea Meteorological Agency (KMA). The validation of estimated value is performed through a match-up with ground truth. Various match-up with ground truth. Various match-up window sizes are tested with 3${\times}$3, 5${\times}$5, 7${\times}$7, 9${\times}$9, 10${\times}$10, 11${\times}$11, 13${\times}$13 pixels to define the spatial representativity of pyranometer measurement, and to consider drifting clouds from adjacent pixels across the ground station during the averaging interval of 1 hour are taken into account.

• 농업과학연구
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• 제38권3호
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• pp.513-524
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• 2011

To evaluate the applicability of inflow runoff model to reservoir operation in Korea, DAWAST model and TPHM model which are conceptual lumped daily runoff model and were developed in Korea, were selected and applied to simulate inflows to Daecheong multipurpose dam with watershed area of 4,134 $km^2$, and water storages in Geryong reservoir with watershed area of 15.1 $km^2$ and total water storage of 3.4 M $m^3$. Evaluating inflows on an yearly, monthly, ten-day, and daily basis, inflows by DAWAST model showed balanced scatters around equal value line. But inflow by TPHM model showed high in high flows. Annual mean water balance by DAWAST model was rainfall of 1,159.9 mm, evapotranspiration of 622.1 mm, and inflow of 644.6 mm, from which rainfall was 104.8 mm less than sum of evapotranspiration and inflow, and showed unbalanced result. Water balance by TPHM model showed satisfactory result. Reservoir water storages were shown to simulate on a considerable level from applying DAWAST and TPHM models to simulate inflows to Geryong reservoir. But it was concluded to be needed to improve DAWAST and TPHM model together from imbalance of water balance and low estimation in high flow.

• Journal of the Korean Wood Science and Technology
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• 제14권3호
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• pp.36-42
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• 1986

The production media and the enzymatic charateristics of laccase from Flammulina velutipes were investigated. The activity of laccase during incubation reached to the maximum at the 40 days of incubation in the case of Barley straw medium. The maximum laccase activity in Barley straw medium was 5 and 16 times higher than those in Onion basic and Sawdust media, respectively. The laccase from Flammulina velutipes has the optimum pH of 6.6 and showed to be stable at relatively broad pH range. 4.5-9.5. Temperature stability showed that above 96% activity could be preserved after holding at 40$^{\circ}C$ for 40 minutes. At the above 70$^{\circ}C$, the laccase activity decreased very rapidly. The Km value of the laccase was estimated to be 28.0 mM which is much higher than that of the laccase from Pleurotus ostreatus. Organic solvents for precipitiation of the enzyme did not inactivation the laccase. Sodium azide which was added for preventing microbial deterioration affected significantly the inactivation of laccase, but this activity was recovered completely by precipitating the enzyme with acetone.

• 대한원격탐사학회지
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• 제22권5호
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• pp.389-396
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• 2006

Surface Solar Insolation is important for vegetation productivity, hydrology, crop growth, etc. In this study, Surface Solar Insolation is estimated using Multi-functional Transport Satellite (MTSAT-1R) in clear and cloudy conditions. For the Cloudy sky cases, the surface solar insolation is estimated by taking into account the cloud transmittance and multiple scattering between cloud and surface. This model integrated Kawamura's model and SMAC code computes surface solar insolation with a $5\;km{\times}5\;km$ spatial resolution in hourly basis. The daily value is derived from the available hourly Surface Solar Insolation, independently for every pixel. To validation, this study uses ground truth data recorded from the pyranometer installed by the Korea Meteorological Agency (KMA). The validation of estimated value is performed through a match-up with ground truth. Various match-up with ground truth. Various match-up window sizes are tested with $3{\times}3,\;5{\times}5,\;7{\times}7,\;9{\times}9,\;10{\times}10,\;11{\times}11,\;13{\times}pixels to define the spatial representativity of pyranometer measurement, and to consider drifting clouds from adjacent pixels across the ground station during the averaging interval of 1 hour are taken into account.

• 한국실천공학교육학회논문지
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• 제3권2호
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• pp.53-62
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• 2011

공학교육의 좋은 예제로써 ET 운동 시 신체가 반응하는 Respiratory Exchange Ratio (호흡교환률 RER, epm)와 Heart Rate (심장박동률 HR, bpm)의 변화분석이다. 에너지소비량, 운동속도, 그리고 체중감량이 달라질 경우 이에 반응하는 혈관순환계에 대한 Health Training Cardiorespiratory 반응을 통해 호흡교환률(RER)과 심장박동률(HR)의 변화에 대해서 연구되어졌다. 연구결과에 따르면 (1)열소비량이 늘어날수록 호흡교환률(RER)은 지속적으로 일정하게 상승하는 반면 심장박동률(HR)은 서서히 상승하다가 임계점을 지나면 갑자기 크게 증가함을 볼 수 있었다. 그리고 그 임계점이 대략 275 Cal 였다. (2)운동속도가 서서히 증가함에 따라서 RER은 역시 서서히 증가하는 반면 HR은 임계점(약 6.7km/h)까지는 서서히 증가하지만 이후에서는 급격한 증가를 보인다. (3)체중감량이 서서히 증가할 때 (또는, 대사 소비량이 늘어남에 따라서) RER은 역시 서서히 증가하였으나 HR은 체중감량과는 무관함을 보였다.

• 동력기계공학회지
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• 제10권2호
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• pp.22-28
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• 2006

Computer simulation of the air flow over an automotive vehicle is now becoming a routine process in automotive industry to assess the aerodynamic characteristics of a medium-size vehicle such as $C_d\;and\;C_1$ and aslo to investigate the possibility of improving aerodynamic performance of the vehicle as a preliminary design for the production line. Mainly due to its contribution in saving time and cost in the development of new cars, computer simulation of the air flow over a vehicle is usually done well before a production car is introduced to the market and in gaining more and more attention as powerful computer resources are getting readily available nowadays. To aerodynamically design a car is mainly related with reducing a drag coefficient of car. A well designed car usually has a $C_d$ value in the range of $0.3{\sim}0.4$. It is understandable that automotive industry is rushing to reduce a drag coefficient as reducing even a small fraction of the $C_d$ value can have an enormous overall impact on many areas. Actually, the present research model was able to achieve a $C_d$ value in the range of $0.3{\sim}0.36$ for flow velocities of $60km/h{\sim}100km/h$ by strategically removing the possible factor hazardous to lower $C_d$ value. Prediction of the medium-size vehicle aerodynamics using CFD was performed when an actual car model was in the development stage and three-dimensional modeling was also performed to optimize it as the best model in terms of the best aerodynamic performance.