• Title/Summary/Keyword: Kim. Han-sup

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Development of an exclusive column method for 82Sr/82Rb generator using a 100 MeV proton linear accelerator of KOMAC

  • Kye-Ryung Kim;Yeong Su Ha;Sang-Pil Yoon;Yeon-ji Lee;Yong-Sub Cho;Hyeongi Kim;Sang-Jin Han;Jung Young Kim;Kyo Chul Lee;Jin Su Kim
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.7 no.2
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    • pp.119-125
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    • 2021
  • 82Sr for 82Rb generator was produced through the irradiation of the proton beam on the nat.RbCI target at the target irradiation facility installed at the end of the Rl-dedicated beamline of the 100 MeV proton linear accelerator of KOMAC (Korea Multi-purpose Accelerator Complex). The average current of the proton beam was 1.2 µA for irradiation time of 150 min. For the separation and purification of the 82Sr from nat.RbCI irradiated, Chelex-100 resin was used. The activities of 82Sr in the irradiated nat.RbCI target solution and after purification were 45.29 µCi and 43.4 µCi, respectively. The separation and purification yield was 95.8%. As an adsorbent to be filled in the generator for 82Sr adsorption hydrous tin oxide was selected. The adsorption yield of 82Sr into the generator adsorbent was > 99 %, and the total amount of 82Sr adsorbed to the generator was 21.6 µCi as of the day of the 82Rb elution experiment. When the elution amount was 22 mL, the maximum82Rb elution yield was 93.3%, and the elution yield increased as the flow rate increased. After the eluted 82Rb was filled in the correction phantom of the small PET for animals, a PET image was taken. The image scan time was set to 5 min, and the phantom PET image was successfully obtained. As results of impurity analysis on eluted 82Rb using ICP-MS, nat.Rb stable isotopes that compete in vivo of 82Rb were identified as undetected levels and were determined to be No-Carrier-Added (NCA).

Comparison on of Activation Functions for Shrinkage Prediction Model using DNN (DNN을 활용한 콘크리트 건조수축 예측 모델의 활성화 함수 비교분석)

  • Han, Jun-Hui;Kim, Su-Hoo;Han, Soo-Hwan;Beak, Sung-Jin;Kim, Jong;Han, Min-Cheol
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2022.11a
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    • pp.121-122
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    • 2022
  • In this study, compared and analyzed various Activation Functions to present a methodology for developing a natural intelligence-based prediction system. As a result of the analysis, ELU was the best with RMSE: 62.87, R2: 0.96, and the error rate was 4%. However, it is considered desirable to construct a prediction system by combining each algorithm model for optimization.

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Valuation of ecosystem services in the organic carbon of the Pinus densiflora forest at Mt. Namsan, Seoul Metropolitan City

  • Lee, Eung-Pill;Lee, Soo-In;Jeong, Heon-Mo;Han, Young-Sub;Lee, Seung-Yeon;Park, Jae-Hoon;Jang, Rae-Ha;Hong, Youg-Sik;Jung, Young-Ho;Kim, Eui-Joo;Lee, Sang-Hun;You, Young-Han
    • Journal of Ecology and Environment
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    • v.43 no.4
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    • pp.341-351
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    • 2019
  • Background: Standing biomass, litter production, rate of litter decomposition, amount of litter on forest floor, and amount of soil organic carbon distribution were investigated from March 2016 to November 2018 in order to evaluate the ecosystem value through organic carbon distribution in the Pinus densiflora forest at Namsan, Seoul Metropolitan City. Results: The amount of organic carbon in the Pinus densiflora forest was 261.09 ton C ha-1 during the research period, and fixed organic carbon in plant through net photosynthesis was 3.2 ton C ha-1 year-1. The organic carbon in plant was 62.77 ton C ha-1 (24.04%), in litter on the forest floor was 3.65 ton C ha-1 (1.40%), and in soil was 194.67 ton C ha-1 (74.56%). The value of plant, litter on forest floor, and soil organic carbon distribution were each 6,277,000 won ha-1, 365, 000 won ha-1, and 19,467,000 won ha-1. The value per ton of fixed organic carbon in plant through net photosynthesis was 320,000 won ha-1 year-1 and the value of ecosystem services stored in carbon in the Namsan forest ecosystem was about 26.1 million won ha-1 for 3 years. Conclusions: The results of this study suggest that the pine forests of Namsan rapidly decompose leaves due to the high atmospheric temperature and accumulate a large amount of organic carbon in the soil to provide climate control regulatory service function.

Adsorption Characteristics of Ni2+, Zn2+ and Cr3+ by Zeolite Synthesized from Jeju Scoria (제주 스코리아로부터 합성한 제올라이트에 의한 Ni2+, Zn2+ 및 Cr3+의 흡착 특성)

  • Kim, Jung-Tae;Lee, Chang-Han;Kam, Sang-Kyu
    • Journal of Environmental Science International
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    • v.29 no.7
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    • pp.739-748
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    • 2020
  • The characteristics of heavy metal ion (Ni2+, Zn2+, and Cr3+) adsorption by zeolite synthesized from Jeju scoria using the fusion and hydrothermal method, were studied. The synthetic zeolite was identified as a Na-A zeolite by X-ray diffraction analysis and scanning electron microscopy images. The equilibrium of heavy metal ion adsorption by synthetic zeolite was reached within 60 min for Ni2+ and Zn2+, and 90 min for Cr3+. The uptake of heavy metal ions increased with increasing pH in the range of pH 3-6 and the uptake decreased in the order of Cr3+ > Zn2+ > Ni2+. For initial heavy metal concentrations of 20-250 mg/L at nonadjusted pH, the adsoption of heavy metal ions was well described by the pseudo second-order kinetic model and was well fitted by the Langmuir isotherm model. The maximum uptake of heavy metal ions obtained from the Langmuir model, decreased in the order of Zn2+ > Ni2+ > Cr3+, differing from the effect of pH on the uptake, which was mainly based on the different pH of the solutions.

A study on investigation of stream drying phenomena in tributaries of the Han River basin and estimation of ecological flow (한강유역 하천건천화 발생 지류하천에 대한 실태조사 및 환경생태유량 산정에 관한 연구)

  • Kim, Yongwon;Kim, Wonjin;Woo, Soyoung;Lee, Yonggwan;Kim, Seongjoon
    • Journal of Korea Water Resources Association
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    • v.57 no.8
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    • pp.519-532
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    • 2024
  • This study aims to investigate stream drying phenomena and determine ecological flow in upper Jungnangcheon basin(118.2 km2) of Han River basin. Satellite imagery was used to compare historical and current land cover, and field surveys, including fish surveys, were conducted to assess stream drying conditions. Satellite image analysis revealed a significant increase in impervious surface area due to the expansion of residential and commercial areas. Streamflow and water quality measurements at Hannae Bridge in study area during the dry season showed and average minimum flow of 1.39 m3/sec and elevated SS levels, indicating poor water quality for T-P and TOC. The representative fish species in the study area was P.herzi. Optimal habitat suitability index for depth, velocity, and substrate were 0.3~0.5 m, 0.1~0.3 m/sec, and sand, respectively. Using PHABSIM, the ecological flow for the study area was estimated as 1.00 m3/sec. The derived ecological flow can be used as a reference flow for stream drying mitigation strategies.

Evaluation of the Inhibitory Effect of Cu2+, Al3+ and Zn2+ on the Activated Sludge (Cu2+, Al3+, Zn2+이 활성슬러지에 미치는 저해영향 평가)

  • Kim, Chang-Gyu;Kim, Yo-Yong;Park, Ik-Beom;Song, Jin-Ho;Nam, Woo-Kyong;Han, Song-Hee;Kim, Bok-Jun;Oh, Jo-Gyo
    • Journal of Korean Society on Water Environment
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    • v.31 no.2
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    • pp.87-93
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    • 2015
  • In this study, the inhibitory effect of toxic metals was investigated on the activated sludge of the municipal sewage treatment plant. The allowable concentration of toxic metals was also estimated for the stable operation of the biological treatment process. The single and mixture toxicity of $Cu^{2+}$, $Al^{3+}$ and $Zn^{2+}$ were evaluated for the activated sludge microorganisms. As a result, nitrifying microorganisms were more susceptible than heterotrophic microorganisms. $IC_{10}$ (Inhibition Concentration of 10%) of $Cu^{2+}$, $Al^{3+}$ and $Zn^{2+}$ for the nitrifying microorganisms was 3 mg/L, 7 mg/L and 25 mg/L, respectively. The mixture toxicity showed three times more sensitive than the single toxicity. The concentrations of $Cu^{2+}$, $Al^{3+}$ and $Zn^{2+}$ to minimize the inhibitory effect on organic matter removal and nitrification in batch experiments were found to be 1.3 mg/L, 2.5 mg/L and 6.3 mg/L.

2020 Han River Basin flood runoff(dam) (2020년 홍수기 한강 유역(주요 댐) 유출 검토)

  • Hwang-Bo, Jong Gu;Shin, In Jong;Kim, Ji Hun;Kang, Jin Sung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.318-318
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    • 2021
  • 2020년 한강 유역의 홍수기(7월 ~ 9월) 3개월 강수량은 1,110.9mm에 달하며 평년대비 131.7%의 상당히 많은 강수량이 관측되었다. 특히 8월은 평년대비 215.2% 강수량을 보이며 큰 홍수사상이 발생하였다.(출처 한강홍수통제소 월간수자원현황및전망) 본 연구에서는 2020년 홍수기 한강 유역 주요 댐의 유입량과 유출량을 분석하였다. 유출입량 산정은 실측자료와 댐 방류량자료를 이용하였다. 산정 결과 달천 괴산댐의 경우 2020년 7월 ~ 2020년 9월, 3개월 동안 유입량(후영교)은 약 5.15억m3이었으며 이 기간의 유출량(댐 방류량)은 약 5.24억m3으로 조사되었다. 같은 기간의 북한강 유역 화천댐 유입량은 산정이 불가능 하였으며 유출량(댐 방류량)은 약 22.24억m3, 춘천댐 유입량(화천댐 방류량 + 용신교 + 오탄교)은 26.86억m3, 유출량(춘천댐 방류량)은 33.60억m3, 의암댐 유입량(춘천댐 방류량 + 소양강댐 방류량)은 55.39억m3, 유출량(의암댐 방류량)은 64.69m3, 청평댐 유입량(의암댐 방류량 + 한덕교 + 목동교)은 78.29억m3, 유출량(청평댐 방류량)은 75.86억m3으로 나타났다. 같은 기간 댐 저류 변화량은 괴산댐 0.002억m3, 춘천댐 0.07억m3, 의암댐 0.15억m3, 청평댐 0.02억m3으로 큰 변화가 없는 것으로 나타났다. 기본적으로 댐 유출량과 유입량의 차는 저류량(저류변화량)과 같아야 한다. 2020년 홍수기(7월~9월) 주요 댐의 유입량, 유출량, 저류량을 검토한 결과 다소 큰 차이를 보였다. 이는 실측 유량의 오차도 일부 있겠지만 댐 저수지 수위 계측의 불확실성, 여수로 방류량의 정확도, 저수지 증발량, 미계측유역의 유출 미고려 등에서 발생하는 오차도 있는 것으로 판단된다.

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Intraperitoneal Paclitaxel Combined with S-1 Plus Oxaliplatin for Advanced Gastric Cancer with Peritoneal Metastasis: a Phase I Study

  • Kim, Dong-Wook;Seo, Won Jun;Youn, Sang Il;Jee, Ye Seob;Jang, You-Jin;Kim, Jong-Han
    • Journal of Gastric Cancer
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    • v.21 no.4
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    • pp.418-425
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    • 2021
  • Purpose: We designed a new regimen by combining intraperitoneal (IP) paclitaxel (PTX) with systemic S-1 plus oxaliplatin (SOX) for the treatment of advanced gastric cancer with peritoneal metastasis. This dose-escalation study aimed to determine the maximum tolerated dose (MTD) and recommended dose (RD) of IP PTX administered weekly to patients. Materials and Methods: Eight cycles of IP PTX plus SOX regimen were administered to the patients. S-1 was administered orally twice daily at a dose of 80 mg/m2/day for 14 consecutive days, followed by 7 days of rest. Intravenous oxaliplatin was administered at a fixed dose of 100 mg/m2 on day 1, while IP PTX was administered on days 1 and 8. The initial dose of IP PTX was 40 mg/m2, and the dose escalation was set in units of 20 mg/m2 up to 80 mg/m2. Dose-limiting toxicities (DLTs) were defined as grade 3 non-hematologic toxicities, grade 4 leukopenia, grade 3 febrile neutropenia, and grade 3 thrombocytopenia. Results: Nine patients were included in the study. No DLTs were observed in any of the enrolled patients. Therefore, the MTD was not reached, and the RD of IP PTX was determined to be 80 mg/m2. Four patients (44%) showed a decreased peritoneal cancer index score on second-look laparoscopic examination. Conclusions: The present study determined the dose for further clinical trials of IP PTX to be 80 mg/m2, when combined with a systemic SOX regimen.