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Alberti's Theory of Architectural Design and Vitruvius (알베르티의 건축 설계론과 비트루비우스)

  • Cho, Eun-Jung
    • The Journal of Art Theory & Practice
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    • no.9
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    • pp.195-215
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    • 2010
  • Alberti's De re aedificatoria is the earliest case in the history of Italian Renaissance architectural treatises dealing with recovery of antiquity through textual and archaeological pursuits. The key source of the Renaissance theoreticians was Vitruvius' De architectura. However, Alberti was keenly aware of inaccuracy and Hellenization of Latinity in this classical text, and tried to compensate them in his own treatise. Furthermore he claimed a reformed discipline of the architects as well as the patrons, and prescribed how future buildings and cities should be built, based on the proper authority of ancient architecture in proper and intelligible Latin. Such an adaptation of classical usage in order to reestablish a modern norm preceded in his earlier work Momus, a satire on the contemporary Italian society of his own by following the model of Lucian. Alberti's suggestion of proper government in Momus's phrase was expanded in De re aedificatoria, for he consider the buildings are subject to the rules of morality and public interests. He proclaimed that the nature of beauty is the reasoned harmony of every part within a body, and architectural beauty also lies on the harmonized arrangement of all the elements within an individual building and of all individual buildings and facilities within a city. For the architects to execute this task, he formulated the concept of lineanenta, the form derived from the mind in order to prescribe the proper place, numbers, scale, and orders for whole building structure. It is the future oriented city-plans and building designs to serve the public interest and the good of all the individual citizens who make up the City-State that Alberti pursued in his treatise.

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experiment and its upgrade with the large silicon charge detector

  • Lee, Jik;Nam, Ji-Woo;Park, Il-Hung;Yang, Jong-Man;Lee, Hye-Young;Na, Go-Woon;Jeon, Jin-A;Suh, Jung-Eun;Lim, Sun-In;Lee, Moo-Hyun;Seo, Eun-Suk
    • Bulletin of the Korean Space Science Society
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    • 2011.04a
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    • pp.20.2-20.2
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    • 2011
  • The NASA Antarctica balloon experiment CREAM has successfully collected the data of energetic cosmic rays during flights in past years. We will present the recent analysis results of the CREAM experiment. We will also report on the launch and recovery process of the latest flight. The silicon charge detector of the CREAM has played the key role in the precision measurement of the charge constitution of energetic cosmic rays. We proposed the upgrade of the CREAM experiment with the installment of a new large silicon charge detector on top of the CREAM instrument. The charge measurement of the large silicon detector with no material in front is expected to improve the accuracy of the CREAM charge measurement drastically when combined with the measurement of the existing double layer silicon detector. We will present the fabrication of the large silicon detector and its performance in the radiation source test as well as in the beam test.

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The Effect of Bee Venom on Scopolamine Induced Memorial Impairment (봉약침액(蜂藥鍼液)이 Scopolamine으로 유발(誘發)된 기억(記憶) 장애(障碍)에 미치는 영향(影響))

  • Song, Jeong-Yeon;Song, Ho-Sueb
    • Journal of Acupuncture Research
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    • v.23 no.3
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    • pp.103-115
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    • 2006
  • Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disease associated with aging in the human population. This disease is characterized by the following 4 structural changes : Atrophy of the Cortex, Parasympathetic, and other neural cells, the existence of Neurofibrillary tangles (NFTs), and the accumulation of Senile plaques. NFTs and Senile plaques is known to be the index of this disease. Senile plaques disturbs the neutro transmission and depletes of Acetylcholine. So, Recovery of Acetylcholine is the primal objective for treating Alzheimer's disease. So, Inhibiting the activity of Acetylcholine Esterase (AChE), which causes the hydrolysus of acetylcholine into choline and acetate, can be seen as a key role for treating Alzheimer's disease. Increasing body of evidence has been demonstrated that Bee Venom Acupuncture (BV) could compete with complex protein involving in multiple step of $NF-_{\kappa}B$ activation and exert the anti -inflammatory potential of combined inhibition of the prostanoid and nitric oxide synthesis systems by inhibition of IKK and $NF-_{\kappa}B$. The effect of BV through behavioral tests after memory impairment induced by Scopolamine. We examined the improving effect of BV on the Scopolamine (1 mg/Kg, i.p.)-induced memorial impairment using passive avoidance response and water maze tests in the mice. BV (0.84, $1.67\;{\mu}g/ml$) reversed the Scopolamine-induced memorial impairment in dose dependent manner. This study therefore suggests that BV acupuncture method may be useful for prevention of development or progression of AD.

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A Study on the Structural Relationship among Technological Determinants, Manufacturing Operations, and Performances for Implementing a Smart Factory in Small Businesses (중소 제조기업의 스마트공장 기술결정요인, 제조운영 및 성과 간 구조적 관계에 관한 연구)

  • Kwon, Se-In;Yang, Jong-Gon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.11
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    • pp.650-661
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    • 2020
  • The digital transformation of the 4th industrial revolution is leading to changes and innovations in the global economy. Various countries are focusing on reviving their manufacturing industries and economic recovery through smart factories. The purpose of this study is to empirically identify technological determinants for the successful implementation of the smart factory and to verify teose effects on manufacturing operations and the firms' operational/environmental performances. Five factors, including sensor network, platform technology, information system, intelligent automation, and safety, were defined as core technologies. The SEM analysis results of 157 small and medium-sized manufacturing firms that have implemented smart factories are as follows. First, sensor network, platform technology, and information system had significant effects on smart manufacturing operations. Second, smart manufacturing operations have improved firm performance. This study is valuable in that it has confirmed the effectiveness of government-funded projects and systemized key technologies for implementing smart factories. Meanwhile, it is helpful for practitioners to support an efficient and effective decision-making for the new adoption.

A Load-Sharing Scheme using SCTP Multi-homing (SCTP 멀티호밍 특성을 활용한 부하 분산 기법)

  • Song Jeonghwa;Lee Meejeong
    • Journal of KIISE:Information Networking
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    • v.31 no.6
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    • pp.595-607
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    • 2004
  • Networks often evolve to provide a host with multiple access points to the Internet. In this paper, we propose a transport layer load distribution mechanism utilizing the multiple network interfaces simultaneously. We specifically propose an extension of Stream Control Transmission Protoco1 (SCTP) to have load sharing over multiple network interfaces. We named the particular service provided by the Proposed load sharing mechanism to be LS (Load Sharing) mode service. LS mode service is based on the following four key elements: (i) the separation of flow control and congestion control, (ii) congestion window based striping, (iii) redundant packet retransmission for fast packet loss recovery, (iv) a novel mechanism to keep track of the receiver window size with the SACKS even if they arrive out-of-order. Through simulations, it is shown that the proposed LS mode service can aggregate the bandwidth of multiple paths almost ideally despite of the disparity in their bandwidth. When a path with a delay of 100% greater is utilized as the second path, the throughput is enhanced about 20%.

Study on Clinical Diseases of Yang Deficiency Pattern (양허증(陽虛證)의 임상적 질환 범위에 대한 고찰)

  • Park, Mi Sun;Ki, Yeong Mok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.2
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    • pp.153-166
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    • 2013
  • Yang deficiency pattern is a representative syndrome differentiation. This article is a study on to which categories of modern diseases yang deficiency is assigned by reference to modern clinical papers and the meaning of yang deficiency interpreted with a perspective of Korean Medicine and a modern perspective. Yang deficiency, yang qi deficiency, lack of yang qi and yang qi debilitation are the words found in "Nei Ching" and yang qi can be interpreted as something to warm, drive and arouse. Zhangzhongjing considered recovery or loss of Yang as the key to life in "Shanghanlun". Danxi proposed "Yang being liable to hyperactivity, Yin being insufficient" and emphasized pathological ministerial fire of Yang exuberance rather than physiological ministerial fire of Yang deficiency. Zhangjingyue proposed "Yang not being in excess, Yin being often deficient" and understood growth and decline of yin qi are all led by yang qi and put emphasis on true yin in addition to yang qi. Diseases of yang deficiency pattern are related with decline of metabolic level, hypofunction of internal secretion, disorder of immune function, disorder of automatic nerve system, sympathetic nerve inhibition, metabolic disorder of microelements, increase of cGMP, change of microcirculation, low speed of blood stream, kidney malfunction. Diseases related with kidney are sterility, polycystic ovary syndrome, spinal stenosis, edema, renal failure, IgA nephropathy, erectile dysfunction, nephritis, prostatitis, benign prostatic hyperplasia, decrease of adrenal cortical hormone by nephrotic syndrome, myelodysplastic syndrome. Disease related with heart are heart failure, arrhythmia, cardiomyopathy, atherosclerosis heart disease, hypertension, hyperlipidemia, pulmonary heart disease. Diseases related with spleen are irritable bowel syndrome, ulcerative colitis. Diseases related with liver are hypothyroidism, liver cirrhosis ascites, hepatitis B, chronic hepatitis, hepatic diabetes. Diseases related with lung are allergic rhinitis, cough variant asthma, bronchial asthma, pulmonary emphysema. And diabetes mellitus, metabolic syndrome, aplastic anemia, headache, encephalatrophy, Alzheimer's disease are also related with yang deficiency.

Thermo-responsive antifouling study of commercial PolyCera® membranes for POME treatment

  • Haan, Teow Yeit;Chean, Loh Wei;Mohammad, Abdul Wahab
    • Membrane and Water Treatment
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    • v.11 no.2
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    • pp.97-109
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    • 2020
  • Membrane fouling is the main drawback of membrane technology. Frequent membrane cleaning and membrane replacement are, therefore, required to reduce membrane fouling that causes permeate flux reduction, lower rejection, or higher operating pressure. Studies have proved that the alteration of membrane properties is the key controlling factor in lessening membrane fouling. Among stimuli-responsive membranes, thermo-responsive membrane is the most popular, with a drastic phase transition and swelling-shrinking behavior caused by the temperature change. In this study, the thermo-responsive ability of two commercial membranes, PolyCera® Titan membrane and PolyCera® Hydro membrane, at different temperatures was studied on the antifouling function of the membrane in palm oil mill effluent (POME) treatment. The evaluation of the membrane's thermo-responsive ability was done through three cycles of adsorption (fouling) and desorption (defouling) processes in a membrane filtration process. The experimental result depicted that PolyCera® Hydro membrane had a higher membrane permeability of 67.869 L/㎡.h.bar than PolyCera® Titan membrane at 46.011 L/㎡.h.bar. However, the high membrane permeability of PolyCera® Hydro membrane was compensated with low removal efficiency. PolyCera® Titan membrane with a smaller mean pore size had better rejection performance than PolyCera® Hydro membrane for all tested parameters. On the other hand, PolyCera® Titan membrane had a better hydrodynamic cleaning efficiency than PolyCera® Hydro membrane regardless of the hydrodynamic cleaning temperature. The best hydrodynamic cleaning performed by PolyCera® Titan membrane was at 35℃ with the flux recovery ratio (FRR) of 99.17 ± 1.43%. The excellent thermo-responsive properties of the PolyCera® Titan membrane could eventually reduce the frequency of membrane replacement and lessen the use of chemicals for membrane cleaning. This outstanding exploration helps to provide a solution to the chemical industry and membrane technology bottleneck, which is the membrane fouling, thus reducing the operating cost incurred by the membrane fouling.

Technical Trends in the Patents and Papers for the Recycling of Organic Residues from Waste Printed Circuit Boards (특허(特許)와 논문(論文)으로 본 폐(廢)PCB 유기계(有機界) 잔유물(殘留物) 재활용(再活用) 기술(技術) 동향(動向))

  • Lee, Dai-Soo;Shin, Sera;Cho, Young-Ju;Cho, Bong-Gyoo
    • Resources Recycling
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    • v.22 no.2
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    • pp.71-77
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    • 2013
  • Electronic products such as appliances, computers, and cellular phones have printed circuit boards (PCBs) in common and the PCBs in the waste electronic products contain valuable metals and organic resins. In Korea, recovery and recycling of the organic resins as well as the valuable metallics from the wastes are required indeed as the most of resources are being imported from abroad. In this article, the patents and papers for the recycling of organic residues from the waste PCBs were collected and analyzed. The open patents of USA (US), European Union (EP), Japan (JP), and Korea (KR) and SCI journals from 1979 to 2012 were investigated. The patents and journals were collected using key-words and filtered by the definition of the technology. The patents and journals were analyzed by the years, countries, companies, and technologies and the technical trends were discussed in this paper. It is showed sluggish relatively activity of published papers and patent applications for polymer manufacturing technology in local and abroad.

Association between Interferon-Inducible Protein 6 (IFI6) Polymorphisms and Hepatitis B Virus Clearance

  • Park, Geun-Hee;Kim, Kyoung-Yeon;Cho, Sung Won;Cheong, Jae Youn;Yu, Gyeong Im;Shin, Dong Hoon;Kwack, Kyu Bum
    • Genomics & Informatics
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    • v.11 no.1
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    • pp.15-23
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    • 2013
  • CD8+T cells are key factors mediating hepatitis B virus (HBV) clearance. However, these cells are killed through HBV-induced apoptosis during the antigen-presenting period in HBV-induced chronic liver disease (CLD) patients. Interferon-inducible protein 6 (IFI6) delays type I interferon-induced apoptosis in cells. We hypothesized that single nucleotide polymorphisms (SNPs) in the IFI6 could affect the chronicity of CLD. The present study included a discovery stage, in which 195 CLD patients, including chronic hepatitis B (HEP) and cirrhosis patients and 107 spontaneous recovery (SR) controls, were analyzed. The genotype distributions of rs2808426 (C > T) and rs10902662 (C > T) were significantly different between the SR and HEP groups (odds ratio [OR], 6.60; 95% confidence interval [CI], 1.64 to 26.52, p = 0.008 for both SNPs) and between the SR and CLD groups (OR, 4.38; 95% CI, 1.25 to 15.26; p = 0.021 and OR, 4.12; 95% CI, 1.18 to 14.44; p = 0.027, respectively). The distribution of diplotypes that contained these SNPs was significantly different between the SR and HEP groups (OR, 6.58; 95% CI, 1.63 to 25.59; p = 0.008 and OR, 0.15; 95% CI, 0.04 to 0.61; p = 0.008, respectively) and between the SR and CLD groups (OR, 4.38; 95% CI, 1.25 to 15.26; p = 0.021 and OR, 4.12; 95% CI, 1.18 to 14.44; p = 0.027, respectively). We were unable to replicate the association shown by secondary enrolled samples. A large-scale validation study should be performed to confirm the association between IFI6 and HBV clearance.

Thermal-structural Analysis and Fatigue Life Evaluation of a Parallel Slide Gate Valve in Accordance with ASME B&PVC (패러럴 슬라이드 게이트밸브의 열구조해석 및 ASME B&PVC 기반 피로수명 평가)

  • Kim, Tae Ho;Choi, Jae Seung;Han, Jeong Sam
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.2
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    • pp.157-164
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    • 2017
  • A parallel slide gate valve (PSGV) is located between the heat recovery steam generator (HRSG) and the steam turbine in a combined cycle power plant (CCPP). It is used to control the flow of steam and runs with repetitive operations such as startups, load changes, and shutdowns during its operation period. Therefore, it is necessary to evaluate the fatigue damage and the structural integrity under a large compressive thermal stress due to the temperature difference through the valve wall thickness during the startup operations. In this paper, the thermal-structural analysis and the fatigue life evaluation of a 16-inch PSGV, which is installed on the HP steam line, is performed according to the fatigue life assessment method described in the ASME B&PVC VIII-2; the method uses the equivalent stress from the elastic stress analysis.