• Title/Summary/Keyword: Key Technology Protection

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Current Evidence on the Association between rs3757318 of C6orf97 and Breast Cancer Risk: a Meta-Analysis

  • Hong, Yuan;Chen, Xue-Qin;Li, Jiao-Yuan;Liu, Cheng;Shen, Na;Zhu, Bei-Bei;Gong, Jing;Chen, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8051-8055
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    • 2014
  • Background: A common genetic variant rs3757318, located in intron of C6orf97, was firstly identified to be associated with breast cancer (BC) risk by a genome-wide association (GWA) study. However, subsequent validation studies with different ethnicities have yielded conflicting results. Materials and Methods: We performed a meta-analysis to synthesize all available data for evaluating the precise effect of this variant on BC susceptibility. Results: A total of 8 articles containing 11 studies with 62,891 cases and 65,635 controls were included in this meta-analysis. When compared to the G allele, the rs3757318-A allele was significantly associated with BC risk with the pooled OR of 1.21 (95% CI=1.15 - 1.29, P<0.001) but with obvious between-study heterogeneity (P=0.040). Stratified analysis suggested that diversity of ethnicity along with control source may explain part of the heterogeneity. Similarly, significant associations were also identified in heterozygote, homozygote, dominant and recessive genetic models. Sensitivity and publication bias analyses indicated robust stability of our results. Conclusions: Our present meta-analysis demonstrated that the variant rs3757318 is associated with increased BC risk. Nevertheless, further studies are needed to clarify the underlying biological mechanisms.

Enhanced Dynamic Segment Protection in WDM Optical Networks under Reliability Constraints

  • Guo, Lei;Cao, Jin;Yu, Hongfang;Li, Lemin
    • ETRI Journal
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    • v.28 no.1
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    • pp.99-102
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    • 2006
  • In this letter, we study the protection problem in wavelength division multiplexing (WDM) optical networks, and propose a novel dynamic heuristic algorithm called differentiated reliable segment protection (DRSP). Differing from previous work, DRSP can effectively avoid the trap problem and is able to find a feasible solution for each connection request. Therefore, DRSP outperforms the previous work. Simulation results have shown to be promising.

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Rapid Detection of SdhBP225F and SdhBH272R Mutations in Boscalid Resistant Botrytis cinerea Strains by ARMS-PCR

  • Liu, Xin;Zeng, Rong;Gao, Shigang;Xu, Lihui;Dai, Fuming
    • The Plant Pathology Journal
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    • v.35 no.1
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    • pp.71-76
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    • 2019
  • $SdhB^{P225F}$ and $SdhB^{H272R}$ mutations have been found associated with boscalid resistance in Botrytis cinerea from strawberry in Shanghai, China. For rapid detection of two mutations, tetra-primers were designed and optimized to gain the relatively high accuracy and specificity based on the ARMS-PCR technique, by which resistance can be identified with different lengths of products on agarose gels. The tetra-primer ARMS-PCR systems for $SdhB^{P225F}$ and $SdhB^{H272R}$ were validated by 9 SdhB-squenced strains repeatedly. Then, sensitivity of 30 more strains were also tested by the methods, which were accordant with genotypes by sequencing and the sensitivity of conidial germination to boscalid by 100%. Thus, the methods developed in this study are proved to be rapid, inexpensive, accurate and practical for resistance detection of Botrytis cinerea caused by $SdhB^{P225F}$ and $SdhB^{H272R}$ mutations.

Characterization of the brittleness of hard rock at different temperatures using uniaxial compression tests

  • Chen, Guoqing;Li, Tianbin;Wang, Wei;Guo, Fan;Yin, Hongyu
    • Geomechanics and Engineering
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    • v.13 no.1
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    • pp.63-77
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    • 2017
  • The failure mechanism of a deep hard rock tunnel under high geostress and high geothermalactivity is extremely complex. Uniaxial compression tests of granite at different temperatures were conducted. The complete stress-strain curves, mechanical parameters and macroscopic failure types of the rock were analyzed in detail. The brittleness index, which represents the possibility of a severe brittleness hazard, is proposed in this paperby comparing the peak stress and the expansion stress. The results show that the temperature range from 20 to $60^{\circ}C$ is able to aggravate the brittle failure of hard rock based on the brittleness index. The closure of internal micro cracks by thermal stress can improve the strength of hard rock and the storage capacity of elastic strain energy. The failure mode ofthe samples changes from shear failure to tensile failure as the temperature increases. In conclusion, the brittle failure mechanism of hard rock under the action of thermal coupling is revealed, and the analysis result offers significant guidance for deep buried tunnels at high temperatures and under high geostress.

Development of a structure analytic hierarchy approach for the evaluation of the physical protection system effectiveness

  • Zou, Bowen;Wang, Wenlin;Liu, Jian;Yan, Zhenyu;Liu, Gaojun;Wang, Jun;Wei, Guanxiang
    • Nuclear Engineering and Technology
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    • v.52 no.8
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    • pp.1661-1668
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    • 2020
  • A physical protection system (PPS) is used for the protection of critical facilities. This paper proposes a structure analytic hierarchy approach (SAHA) for the hierarchical evaluation of the PPS effectiveness in critical infrastructure. SAHA is based on the traditional analysis methods "estimate of adversary sequence interruption, EASI". A community algorithm is used in the building of the SAHA model. SAHA is applied to cluster the associated protection elements for the topological design of complicated PPS with graphical vertexes equivalent to protection elements.

Review of Leptocimbex formosanus group (Hymenoptera: Cimbicidae) with two new Chinese species

  • YAN, Yuchen;NIU, Gengyun;LAN, Bocheng;WEI, Meicai
    • Entomological Research
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    • v.48 no.5
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    • pp.372-383
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    • 2018
  • Leptocimbex formosanus group of Leptocimbex Semenov 1896, Cimbicidae is defined and the relationships and characteristics are provided. Two new species of this group are described from Hunan and Yunnan Provinces in China: Leptocimbex shinoharai Yan & Wei sp. nov. and L. naitoi Yan & Wei sp. nov. Redescriptions of the three known species of L. formosanus group (L. formosanus Enslin 1911, L. dendrobii Rohwer 1915 and L. nigropropodea Wei & Deng 2002) and a key to all known species of this group are provided.

Microwave Assisted Synthesis of SnS Decorated Graphene Nanocomposite with Efficient Visible-Light-Driven Photocatalytic Applications

  • Wang, Jun-Hui;Zeng, Yi-Kai;Gu, Hao;Zhu, Lei;Oh, Won-Chun
    • Korean Journal of Materials Research
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    • v.30 no.12
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    • pp.641-649
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    • 2020
  • A facile microwave assisted solvothermal process is designed for fabricating SnS nanoparticles decorated on graphene nanosheet, which used as visible light driven photocatalyst. Some typical characterization techniques such as XRD, FT-IR, SEM with EDX analysis, and TEM and BET analysis are used to analyse the physical characteristics of as-prepared samples. Spherical SnS nanoparticles are uniformly dispersed on the surface of graphene nanosheet due to ammonia, which can prevent the aggregation of graphene oxide. Meanwhile, microwave radiation provides fast energy that promotes the formation of spherical SnS nanoparticles within a short time. The visible light photocatalytic activity of as-prepared SnS-GR nanocomposites is analysed through photodegradation efficiency of methylene blue with high concentration. According to the higher photocatalytic property, the as-prepared SnS-GR nanocomposites can be expected to be an efficient visible light driven photocatalyst. After five cycles for decolorization, the rate decreases from 87 % to 78 % (about 9 %). It is obvious that the photocatalytic activity of SnS-GR nanocomposite has good repeatability.

Microwave Assisted Synthesis of Graphene-Bi2MoO6 Nanocomposite as Sono-Photocatalyst

  • Tang, Jia-Yao;Zhu, Lei;Fan, Jia-Yi;Sun, Chen;Oh, Won-Chun
    • Korean Journal of Materials Research
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    • v.32 no.1
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    • pp.1-8
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    • 2022
  • In this investigation, Bi2MoO6 deposited graphene nanocomposite (BMG) was synthesized using a simple microwave assisted hydrothermal synthesis method. The synthesized BMG nanocomposite was characterized by X-ray diffraction, transmission electron microscopy, scanning electron microscopy with energy dispersive X-ray analysis, and photocurrent analysis. The study revealed that the catalysts prepared have high crystalline nature, enhanced light responsive property, high catalytic activity, and good stability. XRD results of BMG composite exhibit a koechlinite phase of Bi2MoO6. The surface property is shown by SEM and TEM, which confirmed a homogenous composition in the bulk particles of Bi2MoO6 and nanosheets of graphene. The catalytic behavior was investigated by the decomposition of Rhodamine B as a standard dye. The results exhibit excellent yields of product derivatives at mild conditions under ultrasonic/visible light-medium. Approximately 1.6-times-enhanced sono-photocatalytic activity was observed by introduction of Bi2MoO6 on graphene nanosheet compared with control sample P25 during 50 min test.

Synthesis of Polyamine Grafted Chitosan Copolymer and Evaluation of Its Corrosion Inhibition Performance

  • Li, Heping;Li, Hui;Liu, Yi;Huang, Xiaohua
    • Journal of the Korean Chemical Society
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    • v.59 no.2
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    • pp.142-147
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    • 2015
  • Two new chitosan derivatives, polyamine grafted chitosan copolymers have been synthesized for corrosion protection of carbon steel in acidic medium. First, methyl acrylate graft chitosan copolymer (CS-MAA) was prepared by the reaction of chitosan (CS) and methyl acrylate (MAA) via the Michael addition reaction. Then, CS-MAA was reacted with ethylene diamine (EN) and triethylene tetramine (TN) respectively to synthesize ethylene diamine grafted chitosan copolymer (CS-MAA-EN) and triethylene tetramine grafted chitosan copolymer (CS-MAA-TN), and the structures were characterized by Fourier-transform infrared spectroscopy (FT-IR). At last, the corrosion inhibition activities on Q235 carbon steel were investigated by using gravimetric measurements, metallographic microscope, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) measurements. The compounds CS-MAA-EN and CS-MAA-TN show an appreciable corrosion inhibition property against corrosion of Q235 carbon steel in 5% HCl solution at $25^{\circ}C$. It has been observed that CS-MAA-EN shows greater corrosion inhibition efficiency than CS-MAA-TN. The inhibition efficiency of CS-MAA-EN was close to 90% when the mass fraction concentration was 0.2%~0.3%; the inhibition efficiency of CS-MAA-TN was close to 85% when the mass fraction concentration was 0.02%. The present work provided very promising results in the preparation of green corrosion inhibitors.

A key-insulated CP-ABE with key exposure accountability for secure data sharing in the cloud

  • Hong, Hanshu;Sun, Zhixin;Liu, Ximeng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.5
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    • pp.2394-2406
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    • 2016
  • ABE has become an effective tool for data protection in cloud computing. However, since users possessing the same attributes share the same private keys, there exist some malicious users exposing their private keys deliberately for illegal data sharing without being detected, which will threaten the security of the cloud system. Such issues remain in many current ABE schemes since the private keys are rarely associated with any user specific identifiers. In order to achieve user accountability as well as provide key exposure protection, in this paper, we propose a key-insulated ciphertext policy attribute based encryption with key exposure accountability (KI-CPABE-KEA). In our scheme, data receiver can decrypt the ciphertext if the attributes he owns match with the self-centric policy which is set by the data owner. Besides, a unique identifier is embedded into each user's private key. If a malicious user exposes his private key for illegal data sharing, his identity can be exactly pinpointed by system manager. The key-insulation mechanism guarantees forward and backward security when key exposure happens as well as provides efficient key updating for users in the cloud system. The higher efficiency with proved security make our KI-CPABE-KEA more appropriate for secure data sharing in cloud computing.