• Journal of Institute of Control, Robotics and Systems
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• v.11 no.1
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• pp.84-91
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• 2005

In this paper, we describe the real-time parallel processing simulator developed for the use of performance analysis of rolling missiles. The real-time parallel processing simulator developed here consists of seeker emulator generating infrared image signal on aircraft, real-time computer, host computer, system unit, and actual equipments such as auto-pilot processor and seeker processor. Software is developed from mathematic models, 6 degree-of-freedom module, aerodynamic module which are resided in real-time computer, and graphic user interface program resided in host computer. The real-time computer consists of six TIC-40 processors connected in parallel. The seeker emulator is designed by using analog circuits coupled with mechanical equipments. The system unit provides interface function to match impedance between the components and processes very small electrical signals. Also real launch unit of missiles is interfaced to simulator through system unit. In order to apply the real-time parallel processing simulator to performance analysis equipment of rolling missiles it is essential to perform the performance verification test of simulator.

• Bulletin of the Korean Chemical Society
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• v.33 no.1
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• pp.69-75
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• 2012

Five-channel electrochemical chips were fabricated based on the Micro-electromechanical System (MEMS) technology and were used as platforms to develop DNA arrays. Different kinds of thiolated DNA strands, whose sequences were related to white spot syndrome virus (WSSV) gene, were separately immobilized onto different working electrodes to fabricate a combinatorial biosensor system. As a result, different kinds of target DNA could be analyzed on one chip via a simultaneous recognition process using potassium ferricyanide as an indicator. To perform quantitative target DNA detection, a limit of 70 nM (S/N=3) was found in the presence of 600 nM coexisting noncomplementary ssDNA. The real samples of loop-mediated isothermal amplification (LAMP) products were detected by the proposed method with satisfactory result, suggesting that the multichannel chips had the potential for a high effective microdevice to recognize specific gene sequence for pointof-care applications.

• Journal of Industrial Convergence
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• v.15 no.2
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• pp.1-6
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• 2017

This paper illustrates key features of an enterprise employment simulation which integrates a system dynamic feedback model with a cost-effectiveness optimisation capability utilising genetic algorithms. Its core is a 3-dimensional array structure tracking staff numbers by rank, by time-in-rank, by years-of-service. The resultant model, which could readily be adapted to non-Defence use, can identify, given user specification of any mix of employment rules, the likely patterns of employment behaviour including: resultant time-in-rank and years-of-service profiles; ability of a Unit to fill all positions to target strength; ability to fill promotional positions within normal rules for substantive promotion; need to fill promotional positions using rules for temporary promotion or transfer from outside; necessary recruitment pattern to sustain target strength.

• Journal of Korean Institute of Industrial Engineers
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• v.37 no.1
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• pp.30-40
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• 2011

In recent years, driver information systems (DIS's) became popular and the use of DIS's increased significantly. A majority of DIS's provides touch-screen interfaces because of intuitiveness of the interaction and the flexibility of interface design. In many cases, touch-screen interfaces are mainly manipulated by fingers. In this case, investigating the effect of touch-key sizes on usability is known to be one of the most important research issues, and lots of studies address the effect of touch-key size for mobile devices or kiosks. However, there is few study on DIS's. The importance of touch-key size study for DIS's should be emphasized because it is closely related to safety issues besides usability issues. In this study, we investigated the effect of touch-key sizes of DIS's while simulated driving (0, 50, and 100km/h) considering driving safety (lateral deviation, velocity deviation, total glance time, mean glance time, total time between glances, mean number of glances) and usability of DIS's (task completion time, error rate, subjective preference, NASA TLX) simultaneously. As a result, both of driving safety and usability of DIS's increased as driving speed decreased and touch-key size increased. However, there were no significant differences when touch-key size is larger than a certain level (in this study : 17.5mm).

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.8
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• pp.2964-2983
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• 2015

As the Android operating system has become a key target for malware authors, Android protection has become a thriving research area. Beside the proved importance of system permissions for malware analysis, there is a lot of overlapping in permissions between malware apps and goodware apps. The exploitation of them effectively in malware detection is still an open issue. In this paper, to investigate the feasibility of neuro-fuzzy techniques to Android protection based on system permissions, we introduce a self-adaptive neuro-fuzzy inference system to classify the Android apps into malware and goodware. According to the framework introduced, the most significant permissions that characterize optimally malware apps are identified using Information Gain Ratio method and encapsulated into patterns of features. The patterns of features data is used to train and test the system using stratified cross-validation methodologies. The experiments conducted conclude that the proposed classifier can be effective in Android protection. The results also underline that the neuro-fuzzy techniques are feasible to employ in the field.

• International Journal of Naval Architecture and Ocean Engineering
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• v.10 no.4
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• pp.427-438
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• 2018

The reduction of $CO_2$ emissions has been a key target in the marine industry since the IMO's MEPC published its findings in 2009. Air lubrication method is one of the mature technologies for commercialization to reduce the frictional resistance and enhance fuel efficiency of ships. Air layer is formed by the coalescence of the injected air bubbles beyond a certain air flow rate. In this study, a model ship (${\lambda}=33.33$) of a 50,000 ton medium range tanker is equipped with an air lubrication system. The experiments were conducted in the 100 m long towing tank facility at the Pusan National University. By selecting optimal air injector configuration and distribution ratio between two injectors, the total resistance of model $R_{TM}$ was able to be reduced down to 18.1% in the model scale. Key issue was found to suppress the sideway leakage of injected air by appropriate injection parameters.

• Nuclear Engineering and Technology
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• v.41 no.4
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• pp.531-544
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• 2009

This paper is intended to provide key issues and current research outcomes on accelerator-based Boron Neutron Capture Therapy (BNCT). Accelerator-based neutron sources are efficient to provide epithermal neutron beams for BNCT; hence, much research, worldwide, has focused on the development of components crucial for its realization: neutron-producing targets and cooling equipment, beam-shaping assemblies, and treatment planning systems. Proton beams of 2.5 MeV incident on lithium target results in high yield of neutrons at relatively low energies. Cooling equipment based on submerged jet impingement and micro-channels provide for viable heat removal options. Insofar as beam-shaping assemblies are concerned, moderators containing fluorine or magnesium have the best performance in terms of neutron accumulation in the epithermal energy range during the slowing-down from the high energies. NCT_Plan and SERA systems, which are popular dose distribution analysis tools for BNCT, contain all the required features (i.e., image reconstruction, dose calculations, etc.). However, detailed studies of these systems remain to be done for accurate dose evaluation. Advanced research centered on accelerator-based BNCT is active in Korea as evidenced by the latest research at Hanyang University. There, a new target system and a beam-shaping assembly have been constructed. The performance of these components has been evaluated through comparisons of experimental measurements with simulations. In addition, a new patient-specific treatment planning system, BTPS, has been developed to calculate the deposited dose and radiation flux in human tissue. It is based on MCNPX, and it facilitates BNCT efficient planning based via a user-friendly Graphical User Interface (GUI).

• Herbal Formula Science
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• v.26 no.3
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• pp.237-250
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• 2018

Objectives : This study is a pharmacological network approach, aimed to identify the potential active compounds contained in Curcumae Radix, and their associated targets, to predict the various bio-reactions involved, and finally to establish the cornerstone for the deep-depth study of the representative mechanisms. Methods : The active compounds of Curcumae Radix have been identified using Traditional Chinese Medicine System Pharmacology Database and Analysis Platform. The UniProt database was used to collect each of information of all target proteins associated with the active compounds. To find the bio-metabolic processes associated with each target, the DAVID6.8 Gene Functional classifier tool was used. Compound-Target and Target-Pathway networks were analyzed via Cytoscape 3.40. Results : The target information from 32 potential active compounds of Curcumae Radix was collected through TCMSP analysis. The active compounds interact with 133 target genes engaging in total of 885 biological pathways. The most relevant pathway was the lipid-related metabolism, in which 3 representative active compounds were naringenin, oleic acid, and ${\beta}-sitosterol$. The mostly targeted proteins in the lipid pathway were ApoB, AKT1 and PPAR. Conclusions : The pharmacological network analysis is convenient approach to predict the overall metabolic mechanisms in medicinal herb research, which can reduce the processes of various experimental trial and error and provide key clues that can be used to validate and experimentally verify the core compounds.

• Journal of the Korea Institute of Military Science and Technology
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• v.26 no.2
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• pp.129-138
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• 2023

Acquiring precise coordinates of ground targets can be regarded as the key mission of the tactical-level military UAS(Unmanned Aerial System) operations. The coordinates deviations for the ground targets estimated from UAV (Unmanned Aerial Vehicle) images may depend on the sensor specifications and slant ranges between UAV and ground targets. It has an order of several tens to hundreds of meters for typical tactical UAV mission scenarios. In this paper, we propose a scheme that precisely acquires target coordinates from UAS by mapping image pixels to geographical coordinates based on GCP(Ground Control Points). This scheme was implemented and tested from ground control station for UAS. We took images of targets of which exact location is known and acquired the target coordinates using our proposed scheme. The experimental results showed that errors of the acquired coordinates remained within an order of several meters and the coordinates accuracy was significantly improved.

• Journal of Microbiology and Biotechnology
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• v.25 no.6
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• pp.936-940
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• 2015

Human papillomavirus (HPV) type 52 is a high-risk HPV responsible for cervical cancer. HPV type 52 is common around the world and is the most common in some Asian regions. The available prophylactic HPV vaccines protect only from HPV types 16 and 18. Supplementing economical vaccines that target HPV type 52 may satisfactorily complement available prophylactic vaccines. A codon-adapted HPV 52 L1 gene was expressed in the methylotrophic yeast Hansenula polymorpha, which is used as an industrial platform for economical hepatitis B surface antigen particle production in China. We found that the recombinant proteins produced in this expression system could form virus-like particles (VLPs) with diameters of approximately 50 nm. This study suggests that the HPV 52 VLPs produced in this platform may satisfactorily complement available prophylactic vaccines in fighting against HPVs prevalent in Asia.