• Communications for Statistical Applications and Methods
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• v.5 no.3
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• pp.685-694
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• 1998

임상실험이나 신뢰성공학 분야에서 임의 중단자료를 이용한 비모수적 신뢰도 추정량으로 Kaplan-Meier 추정량과 Nelson형 추정량이 많이 사용되고 있다. 그러나 Nelson형 추정량은 평균제곱오차의 관점에서 Kaplan-Meier 추정량보다 추정능력이 우수한 반면 편의는 신뢰도가 감소함에 따라 양의 방향으로 점증하는 소표본 특성을 갖는다. Nelson형 추정량의 이러한 특성 때문에 신뢰도의 함수로 표현되는 잔여수명 분위수함수 등의 추정시에는 평균제곱오차의 관점에서 Kaplan-Meier 추정량보다 추정능력이 떨어짐을 볼 수 있다. 이러한 점을 고려하여 이 두 추정량을 가중평균으로 통합한 새로운 비모수적 신뢰도 추정량을 제안하고 추정량의 특성을 비교 분석하였다.

• The Korean Journal of Applied Statistics
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• v.34 no.6
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• pp.957-968
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• 2021

Inverse censoring probability weighting (ICPW) is a popular technique in survival data analysis. In applications of the ICPW technique such as the censored regression, it is crucial to accurately estimate the censoring probability. A simulation study is undertaken in this article to see how censoring probability estimate influences model performance in censored regression using the ICPW scheme. We compare three censoring probability estimators, including Kaplan-Meier (KM) estimator, Cox proportional hazard model estimator, and local KM estimator. For the local KM estimator, we propose to reduce the predictor dimension to avoid the curse of dimensionality and consider two popular dimension reduction tools: principal component analysis and sliced inverse regression. Finally, we found that the Cox proportional hazard model estimator shows the best performance as a censoring probability estimator in both mean and median censored regressions.

• Journal of the Korean Data and Information Science Society
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• v.11 no.2
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• pp.225-233
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• 2000

In life-testing experiments, in which the longest time an experimental unit is on test is not a failure time, but rather a censored observation. For the situation the Kaplan-Meier estimator is known to be a baised estimator of the survival function. Several modifications of the Kaplan-Meier estimator are examined and compared with bias and mean squared error.

• Proceedings of the Korean Statistical Society Conference
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• 2005.05a
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• pp.251-255
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• 2005

중도절단된 자료와 표본수가 적은 자료를 가지는 생존분석에서 생존율을 추정하거나 두 집단의 생존율을 비교할 때 정규분포 근사를 가정한 신뢰구간을 이용하는 데는 많은 어려움이 생긴다. 생존함수의 신뢰구간에 대한 중도절단을, 표본의 크기에 따른 다양한 상황의 모의실험을 통하여 Kaplan-Meier, Nelson, 적률 추정량 그리고 cox model의 ${\beta}$을 가지고 붓스트랩을 이용한 신뢰구간과 비모수 신뢰구간, 우도비 신뢰구간의 실제 포함 확률을 비교해보고자 한다.

• The Korean Journal of Applied Statistics
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• v.25 no.2
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• pp.311-319
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• 2012

The simplest and the most important distribution in survival analysis is exponential distribution. Koziol and Green (1976) derived Cram$\acute{e}$r-von Mises statistic's randomly censored version based on the Kaplan-Meier product limit estimate of the distribution function; however, it could not be practical for a real data set since the statistic is for testing a simple goodness of fit hypothesis. We generalized it to the composite hypothesis for exponentiality with an unknown scale parameter. We also considered the classical Kolmogorov-Smirnov statistic and generalized it by the exact same way. The two statistics are compared through a simulation study. As a result, we can see that the generalized Koziol-Green statistic has better power in most of the alternative distributions considered.

• The Korean Journal of Applied Statistics
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• v.24 no.5
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• pp.883-891
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• 2011

For survival data we sometimes want to test a log normality hypothesis that can be changed into normality by transforming the survival data. Hence the Shapiro-Wilk type statistic for normality is generalized to randomly censored data based on the Kaplan-Meier product limit estimate of the distribution function. Koziol and Green (1976) derived Cram$\acute{e}$r-von Mises statistic's randomly censored version under the simpl hypothesis. These two test statistics are compared through a simulation study. As for the distribution of censoring variables, we consider Koziol and Green (1976)'s model and other similar models. Through the simulation results, we can see that the power of the proposed statistic is higher than that of Koziol-Green statistic and that the proportion of the censored observations (rather than the distribution of censoring variables) has a strong influence on the power of the proposed statistic.

• Journal of the Korean Data and Information Science Society
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• v.14 no.2
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• pp.279-287
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• 2003

In this paper we propose a local smoothing of the Nelson type estimator for the survival function based on an approximation by the Weibull distribution function. It appears that Mean Square Error and Bias of the smoothed estimator of the Nelson type survival function estimators are significantly smaller than that of the smoothed estimator of the Kaplan-Meier survival function estimator.

• 한국데이터정보과학회:학술대회논문집
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• 2003.05a
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• pp.109-119
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• 2003

In this paper we propose a local smoothing of the Nelson type estimator for the survival function based on an approximation by the Weibull distribution function. It appears that Mean Square Error and Bias of the smoothed estimator of the Nelson type survival function estimator is significantly smaller then that of the smoothed estimator of the Kaplan-Meier survival function estimator.

• The Korean Journal of Applied Statistics
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• v.31 no.6
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• pp.761-769
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• 2018

Simulations are important for survival analyses that deal with censored data. Cox models are widely used in survival analyses, therefore, we investigate how to generate censored data that can simulate the Cox model. Bender et al. (Statistics in Medicine, 24, 1713-1723, 2005) provided a parametric method for generating survival times, but we need to generate censoring times as well as survival times to simulate the censored data. In addition to the parametric method for generating censored data, a nonparametric method is also proposed and applied to a real data set.

• Childhood Kidney Diseases
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• v.9 no.2
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• pp.167-174
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• 2005

Purpose : Relapses are a major problem in children with steroid responsive nephrotic syndrome(SRNS). This study has been performed to determine the predictive factors for relapse in children with SRNS. Methods : The study group consisted of 7,3 children with SRNS who had been admitted to the Department of Pediatrics, Kyungpook National University Hospital, over 6 years from 1996 to 2001. The medical records were reviewed retrospectively and analyzed to determine significant relationships between selected variables[age at onset, sex, laboratory data, the rapidity of response(days to remission), interval to first relapse] and the frequency of relapse. Results : The age($mean{\pm}SD$) of patients was $4.53{\pm}2.53$ years old. The male to female ratio was 52:21. In 95$\%$, 39 out of the 41 children had a renal biopsy, and the final diagnosis was minimal change nephrotic syndrome. There was no significant correlation between the frequency of relapse and the following variables age at onset, sex, and presence of hematuria. However, the rapidity of response correlated well with the frequency of relapse, especially during the first year after the onset of the disease(P=0.005). Conclusion : The rapidity of response is expected to be one of the predictive (actors for relapse in children with SRNS. (J Korean Soc Pediatr Nephrol 2005;9:167-174)