• Title/Summary/Keyword: Kangwon National University

Search Result 16,157, Processing Time 0.043 seconds

Antiobese Effects of Diet Containing Medicinal Plant Water Extracts in High Fat Diet-Induced Obese Mice (약용식물 물 추출물들 혼합식이에 의한 고지방식이로 유도된 마우스의 비만 억제효과)

  • Seo, Dong-Joo;Chung, Mi-Ja;Kim, Dae-Jung;Choe, Myeon
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.38 no.11
    • /
    • pp.1522-1527
    • /
    • 2009
  • We investigated the effects of feeding diet containing medicinal plant water extracts (MPWEs) on body weight, epididymal adipose tissue weight, adipocyte size of epididymal adipose tissue and plasma lipid levels in high fat (HF) diet-induced obese mice. To test antiobese effects of diet containing the MPWEs, C57BL/6J mice were fed with HF diet for 11 weeks. In the last 6 weeks, the HF diet was supplemented with 0 (HFD) or MPWEs (5 g/kg, HFD+MPWEs) or orlistat [0.5 g/kg, HFD+orlistat (antiobesity drug)]. The HF-free diet group was fed normal chow for 11 weeks. Eleven-weeks feeding with HFD resulted in significant increase in lipid levels, body weight, liver and epididymal adipose tissue weights, compared with the HF-free group. Diet containing MPWEs significantly reduced plasma total cholesterol, LDL-cholesterol, triglyceride and glucose concentrations as well as body weight, liver weight and epididymal adipose tissue weight. Plasma triglyceride levels were significantly lower in the HFD+Forlistat group after 6 weeks and a similar effect was found with HFD+MPWEs group. The adipocyte size of epididymal adipose tissue in HFD group was significantly larger than those of HF-free group. MPWEs and orlistat (positive control) significantly decreased the size of epididymal adipocytes but orlistat was slightly more effective than MPWEs. These results suggest that oral feeding of the MPWEs may have antiobesity effects by suppressing body weight gain, adipose tissue formation and adipocyte size increase.

Morphological Characteristic of Immature stage in Platypus koryoensis (Murayama) (Coleoptera, Platypodidae) and Local Variation in the Number of Mycangia (광릉긴나무좀의 미성숙 충태별 형태특성과 유충령기, 균낭수의 지역별 변이 (딱정벌레목, 긴나무좀과))

  • Won, Dae-Sung;Choi, Won Il;Kwon, Young-Dae;Kim, Kyung Hee;Kim, Jong Kuk
    • Journal of Korean Society of Forest Science
    • /
    • v.102 no.2
    • /
    • pp.305-308
    • /
    • 2013
  • This study was conducted to describe the external morphology of Platypus-koryoensis Murayama in immature stage, to determine each instar based on larvae head-capsule, and to measure individual and local variations in the number of mycangia of adult. Egg of P. koryoensis, had oval shape and lengths of the major and minor axis were $0.67{\pm}0.051$ mm and $0.41{\pm}0.053$ mm, respectively. Body colour of $5^{th}$ instar was gloss white with well-developed mandible. Larvae of P. koryoensis grew up to $5^{th}$ instar and each instar was clearly classified by head capsule width. Head capsule width for $1^{st}$, $2^{nd}$, $3^{rd}$, $4^{th}$, and $5^{th}$ instar larvae were $0.35{\pm}0.004$ mm, $0.45{\pm}0.010$ mm, $0.67{\pm}0.039$ mm, $0.94{\pm}0.069$ mm and, $1.12{\pm}0.007$ mm, respectively. The colour of pupa was pale yellow and its length was $4.64{\pm}0.044$ mm. The number of mycangia per female had individual variations from 5 to 12 and 83% of the adults had from 6 to 8 mycangia. There was no significant difference in number of mycangia collected from between Namyangju region and Honchen region.

Isolation and Identification of α-Glucosidase Inhibitory Compounds, Hyperoside, and Isoquercetin from Eleutherococcus senticosus Leaves (가시오갈피(Eleutherococcus senticosus) 잎으로부터 α-Glucosidase의 저해 활성 물질, Hyperoside와 Isoquercetin의 분리 및 구조·동정)

  • Lee, Ki Yeon;Hong, Soo Young;Jeong, Hye Jeong;Lee, Jae Hyoung;Lim, Sang Hyun;Heo, Nam-Kee;Kim, Songmun;Kim, Hee-Yeon
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.43 no.12
    • /
    • pp.1858-1864
    • /
    • 2014
  • In the present investigation, the anti-diabetic potential of 80% ethanol extract of Eleutherococcus senticosus leaves (EEES) was examined based on ${\alpha}$-glucosidase inhibitory activities. EEES was sequentially fractionated with n-hexane, chloroform, ethyl acetate (EtAOc), n-butanol, and $H_2O$. Of the various fractions, EtAOc fraction effectively inhibited ${\alpha}$-glucosidase activity by 68.05%. Therefore, EtAOc fraction was selected for further isolation and identification studies. EtAOc fraction was separated by medium pressure liquid chromatography with silica and ODS gel to yield eight fractions (EAA~EAH). Based on the results of ${\alpha}$-glucosidase inhibitory activity, EAH fraction was re-chromatographed to yielded four more fractions (EAHA~EAHD). Of these, EAHC fraction showed higher ${\alpha}$-glucosidase inhibitory activity of 93.60%. EAHC fraction was re-chromatographed and yielded EAHCA and EAHCB fractions. Further, identification and chemical structures of these two fractions were analyzed using $^1H$-NMR, $^{13}C$-NMR, and mass spectra data. Based on the results of the spectral data, the isolated compounds were identified as hyperoside and isoquercetin. Results of the present study indicate that the isolated compounds, hyperoside, and isoquercetin from leaves of E. senticosus could be used for the development of new anti-diabetic drugs.

A Study on the Factors of Individual Acceptance for Online Game (온라인게임의 개인적 수용 요인에 관한 연구)

  • Yoon, Gun-Woo;Kim, Won-Joon;Ryu, Seoung-Ho
    • Journal of Korea Game Society
    • /
    • v.9 no.3
    • /
    • pp.107-119
    • /
    • 2009
  • Online games belong to a technology-oriented service industry that has emerged from the assimilation of game contents and communication networks in the respective realms of culture technology (CT) and information technology (IT). This study examines the individual acceptance of online games as entertainment-oriented technology based on the belief-attitude-intention paradigm and the underlying hedonic and utilitarian motivations. To measure the latent variables influencing the acceptance process, a structured questionnaire was developed based on the existing Technology Acceptance Model. Research model analysis and hypothesis testing were carried out using a structural equation model. Results indicated that latent variables reflecting hedonic and utilitarian characteristics had a significant influence on user behavior in the acceptance of online games. By uncovering the core factors in! fluencing the acceptance of online games and thereby theoretically verifying the latent variables influencing the acceptance of entertainment-oriented technology, this study provides strategic implications for business models by game companies aimed at attracting a large user base and dominating the market.

  • PDF

Scoring Korean Written Responses Using English-Based Automated Computer Scoring Models and Machine Translation: A Case of Natural Selection Concept Test (영어기반 컴퓨터자동채점모델과 기계번역을 활용한 서술형 한국어 응답 채점 -자연선택개념평가 사례-)

  • Ha, Minsu
    • Journal of The Korean Association For Science Education
    • /
    • v.36 no.3
    • /
    • pp.389-397
    • /
    • 2016
  • This study aims to test the efficacy of English-based automated computer scoring models and machine translation to score Korean college students' written responses on natural selection concept items. To this end, I collected 128 pre-service biology teachers' written responses on four-item instrument (total 512 written responses). The machine translation software (i.e., Google Translate) translated both original responses and spell-corrected responses. The presence/absence of five scientific ideas and three $na{\ddot{i}}ve$ ideas in both translated responses were judged by the automated computer scoring models (i.e., EvoGrader). The computer-scored results (4096 predictions) were compared with expert-scored results. The results illustrated that no significant differences in both average scores and statistical results using average scores was found between the computer-scored result and experts-scored result. The Pearson correlation coefficients of composite scores for each student between computer scoring and experts scoring were 0.848 for scientific ideas and 0.776 for $na{\ddot{i}}ve$ ideas. The inter-rater reliability indices (Cohen kappa) between computer scoring and experts scoring for linguistically simple concepts (e.g., variation, competition, and limited resources) were over 0.8. These findings reveal that the English-based automated computer scoring models and machine translation can be a promising method in scoring Korean college students' written responses on natural selection concept items.

Examining the Validity of History-of-Science-Based Evolution Concept Assessment and Exploring Conceptual Progressions by Contexts (과학사에 근거한 진화개념검사도구의 타당도 확인 및 맥락에 따른 진화개념 발달 탐색)

  • Ha, Minsu
    • Journal of The Korean Association For Science Education
    • /
    • v.36 no.3
    • /
    • pp.509-517
    • /
    • 2016
  • Previous studies have investigated the similarity between the development of evolutionary explanations and students' conceptual developments on evolution. However, the validity and reliability of the assessment method reflecting the similarity have not been quantitatively examined yet. In addition, no study has examined the conceptual progressions of evolution concept based on contexts although literature has addressed the contextual difference of evolutionary explanation in the history of science. This study examined the validity and reliability of history-of-science-based evolution concept assessment using ordered multiple choice (OMC) methods and Rasch analysis and explored conceptual progression by three contexts (e.g., human, animal, and plant). The evolution concept assessment developed by Ha (2007) was used to examine 1711 elementary, middle, and high school students, and pre- and in-service science teachers' (biology majors and non-majors) evolution concepts. Internal consistency reliability and item response fitness of the OMC method that provide 0- to 4-point scores to creationism, teleology, intentionality, use/disuse, and natural selection respectively met the benchmark based on the Cronbach alpha and MNSQ indices of Rasch analysis. The level of elementary and middle school students' evolution concepts were located between intentionality and use/disuse while the level of high school and non-biology science teachers' evolution concepts were located between use/disuse and natural selection. The conceptual progressions of evolution concepts were differentiated according to three contexts. This study provided the quantitative evidence for the similarity between the development of evolutionary explanations and students' conceptual developments on evolution and suggest new analysis methods (i.e., OMC) of evolution concept assessment.

An Analysis of the Association between Subject Matter Knowledge and Pedagogical Content Knowledge for Science Teachers: The Case of Earth Science Teachers' Lesson on Atmospheric Pressure (과학 교사의 교과내용학지식과 교과교육학지식의 연관성 분석: 지구과학 교사의 대기압 수업 사례)

  • Lee, Ki-Young
    • Journal of The Korean Association For Science Education
    • /
    • v.33 no.6
    • /
    • pp.1219-1236
    • /
    • 2013
  • The purpose of this study was to investigate the association between subject matter knowledge (SMK) and pedagogical content knowledge (PCK) for science teachers. To this end, a total of 26 secondary Earth science teachers participated in this study and a concept diagnostic questionnaire and a lesson planning task of atmospheric pressure were devised to give an indication of participating teachers' SMK and PCK, respectively. The results of this study are summarized as follows: First, participating teachers showed a variety of SMK levels about atmospheric pressure. Second, teachers at high level of SMK focused on 'supplementary' and 'fundamental' curriculum contents for in-depth conceptual understanding, but teachers at low level of SMK, on the contrary, stressed 'applicative' curriculum contents. Third, teachers at high level of SMK grasped students' misconceptions and difficulties in learning atmospheric pressure far more concretely than teachers at low level of SMK. Lastly, teachers at high level of SMK showed a tendency to use learner-centered instructional strategy by utilizing students' prior knowledge, but teachers at low level of SMK were inclined toward teacher-directed concept explanation. Based on this study, some implications for effective science teacher preparation programs were also discussed.

Analyzing Korean Pre-service Biology Teachers' Understanding of the Concept of Natural Selection in Comparison with Chinese, American, and German Biology Majors (중국, 미국, 독일의 생물전공자와 비교한 한국 생물예비교사의 자연선택개념 이해 수준 분석)

  • Ha, Minsu
    • Journal of The Korean Association For Science Education
    • /
    • v.36 no.5
    • /
    • pp.729-737
    • /
    • 2016
  • Natural selection is the core idea of evolution that pre-service biology teachers need to understand to solve diverse biological problem. This study aims to investigate the level of Korean pre-service biology teachers' understanding of natural selection by comparing their knowledge with their Chinese, American, and German biology major undergraduate counterparts. In particular, this study focuses on two conceptual components of natural selection (i.e., ecology and genetics). This study used a total 1226 pre-service biology teachers and biology majors' data. The instrument measuring the understanding of natural selection concepts was Conceptual Inventory of Natural Selection, which consists of ten ecology concept items and ten genetics concept items. The Rasch model analysis, multivariate analysis of variance, and univariate analysis of variance were used for the statistical tests. The result reveals that the level of Korean pre-service biology teachers' understanding of natural selection were similar with Chinese undergraduates' understanding and significantly lower than American and German undergraduates.' In the first year student data, the level of genetics concept of Korean pre-service biology teachers were significantly lower than Chinese and German students. In the fourth year student data, the level of ecology concept of Korean pre-service biology teachers were significantly lower than American and German students. Based on these results, the ecology concept education and balanced natural selection concept education are discussed.

Characteristic of Microcracks with Mixing Proportional Properties of Concrete (미세균열이 콘크리트의 염소이온 침투에 미치는 영향 III; 배합조건 특성에 따른 미세균열의 특성)

  • Yoon, In-Seok;Kim, Young-Geun;Park, Ki-Bong
    • Journal of the Korea Concrete Institute
    • /
    • v.20 no.4
    • /
    • pp.469-475
    • /
    • 2008
  • It is obvious that chloride penetration through cracks can threaten the durability of concrete substantially, according to the previous studies of author. It was proposed that crack depth corrseponded with critical crack width from the surface is a crucial factor in view of durability design of concrete structures. It is now necessary to deal with chloride penetration through microcracks characterized with the mixing features of concrete. The purpose of this study is examining the effect of mix proportional features of concrete such as coarse aggregate, high strengtherize of concrete and reinforcement of steel fiber on chloride penetration through cracks. Although small size of coarse aggregate can lead to many microcracks in concrete, the cracks should not impact on chloride penetration directly. On the contrary, chloride should penetrate through cracks easily in concrete with a large size of coarse aggregate because mixrocracks are connected to each other. Second, high strength concrete has an excellent performance to resist with chloride penetration. However, for cracked high strength concrete, its performance is reduced upto the level of ordinary concrete. Finally, steel fiber reinforcement is effective to reduce chloride penetration through cracks because steel fiber reinforcement can lead to reduce crack depth significantly.

Expansion Behavior of Aggregate of Korea due to Alkali-Silica Reaction by ASTM C 1260 Method (ASTM C 1260 실험에 의한 국내 골재의 알칼리-실리카 반응 팽창 특성)

  • Yun, Kyong-Ku;Hong, Seung-Ho;Han, Seung-Hwan
    • Journal of the Korea Concrete Institute
    • /
    • v.20 no.4
    • /
    • pp.431-437
    • /
    • 2008
  • The concrete pavement at Seohae Expressway in Korea has suffered from serious distress, only after four to seven years of construction. The deterioration of ASR has seldom been reported per se in Korea, because the aggregate used for the cement concrete has been considered safe against alkali-silica reaction so far. The purpose of this study is to examine the expansion behavior of aggregates of Korea due to alkali-silica reaction by ASTM C 1260 standard method of the accelerated mortar bar test (AMBT), stereo microscopic analysis, scanning electronic microscope (SEM) analysis, and electron dispersive X-ray spectrometer (EDX) analysis. The results are presented as it follows. The accelerated mortar bar test (AMBT) showed that mica granite and felsite of igneous rocks, aroke, red sandstone and shale of sedimentary rocks, slate of metamorphic rock, and dendrite and quartz of mineral rock showed more expansion than 0.1% at 14 days. But, some sedimentary rocks and metamorphic rocks expanded more than 0.1% at 28 days even though they were less than 0.1% at 14 days. The mortar bars, which showed more than occurred 0.1% expansion, resulted in cracking on surface. SEM and EDX analysis confirmed that the white gel was a typical reaction product of ASR. The ASR gel in Korea mainly consisted of Silicate (Si) and Potassium (K) from the cement. The crack in the concrete pavement was caused by ASR. It seems that Korea is no longer safe zone against alkali-silica reaction.