• 대한의생명과학회지
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• 제9권1호
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• pp.29-36
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• 2003

Progesterone levels in the blood plasma or skim milk of cows are considered to be very useful indicator fur the detection of estrus cycle and early pregnancy diagnosis. During 13 to 14 days after estrus the level of progesterone in plasma or skim milk were not different between the inseminated arid non-inseminated cows. In the pregnant cows the peak level of progesterone reached on 14th day after artificial insemination (AI), but in the absence of conceptus the level declines after the 14th day slowly, and then very rapidly towards the basal level after the 17th day. This low level persists about 4 days, including those of estrus and ovulation a highly characteristic pattern which differs so markedly from that in the pregnant cows. Progesterone levels in blood plasma or skim milk can provided a reliable diagnosis of early pregnancy and monitoring ovarian activity in cows. The mean $\pm$ standard deviation of milk urea nitrogen(MUN) and protein concentration in the cows at 9 herds were 17.7$\pm$2.35 mg/dL and 3.2$\pm$0.17%, respectively. The days of nonpregnant after parturition was shorter in the cows in which the lower level of MUN than higher level of MUN concentration.

• 대한수의학회지
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• 제33권3호
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• pp.539-545
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• 1993

This study was carried out the determine the progesterone concentration for serum by enzyme-linked immunosorbent assay(ELISA) in bovine adult at estrous, pregnant, after patuation and male, female calves of 1 month old, respectively. The results obtained were summarized as follows ; 1. The assay has a sesitivity of $0.1ng/m{\ell}$. 2. Intra and inter-assay coefficient of variation were 4.5%, 6.1~9.4% when used for the determination of progesterone in samples of bovine serum. 3. The percentages of recovery for progesterone added were between 88.0 to 88.9%. 4. Progesterone concentration of adult bovine serum at estrus, pregnant and after 1 day of parturition were $0.37{\pm}0.16$, $7.1{\pm}1.0$, $0.13{\pm}0.02ng/m{\ell}$, respectively. 5. There was no differences in serum progesterone concentration of calves both male($0.16{\pm}0.03ng/m{\ell}$) and female($0.15{\pm}0.04ng/m{\ell}$) on 1 month old. From these results, progesterone determination by ELISA is very applicable to detect of early pregnancy diagnosis, factorial analysis of reproductive disorder, and also reproductive physiological functions such as veterinary therapeutic measures and monitoring of cyclicity.

• 대한수의학회지
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• 제32권4호
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• pp.677-681
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• 1992

This experiment was carried out to establish a proper method of indocyanine green(ICG) excrection test for a applicable liver function test in three Korean native cattle average weighing about 450kg and dairy cattle parity of 3~5. The results obtained the half life($T^1/_2$), fractional clearance rate(KICG), retention rate and plasma enzyme activities before or after injection of ICG were as follows. 1. The maximum absorbance of ICG in plasma was at 805nm. 2. Average half life and fractional clearance rate following the injection of ICG 0.25mg/kg body weight were $5.53{\pm}1.27$ minute and $0.131{\pm}0.031$/minute in Korean native cattle, $4.55{\pm}0.68$ minute and $0.156{\pm}0.031$/minute in dairy cattle, respectively. The ICG removal rate was exponentially liner for the first 15 minutes after injection both of Korean native cattle and dairy cattle. 3. Average plasma retention rate when 10, 15, 30 minutes after injection was $35.7{\pm}13.9$, $23.2{\pm}7.1$, $10.8{\pm}3.5%$ in Korean native cattle, $26.8{\pm}3.3$, $14.2{\pm}1.2$, $5.5{\pm}2.2%$ in dairy cattle, respectively. 4. Plasma enzyme activities(AST, ALT, r-GTP) were no variation among the before, during and after injection of ICG. From these results, ICG excretion test to cattle is applicable to evaluation of liver funtion in both clinical and research, and adopted the 15 minutes plasma sample as the sample taken at the ideal time for comparative purposes.

• 대한수의학회지
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• 제45권2호
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• pp.287-296
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• 2005

This experiments was designed to observe the effect of period and dose of ingestion of grapes on renal failure in dog. After the dogs had been mixed of general feed, raisins from U.S.A and fresh grapes from Chile selling in Korea. We observed the clinical sign, and analyzed the blood and urine using by biochemical test. The experiment was executed by the two following groups. The experiment group 1. derived renal failure by supplying the mixed general feed with fresh grapes and dry grapes 15 g per weight kg, 2 times a day (AM 09, PM 21), the experiment group 2. executed to derive renal failure by supplying the mixed general feed with fresh grapes and dry grapes 40 g per weight kg, 2 times a day. Extraction of blood for analysis was conducted one time a day and clinical test for renal failure was executed by means of a blood analysis, biochemical analysis, urine analysis, excretory urography (E.U) and E.R.D-$screen^{TM}$ urine test (Heska, USA). The results of group 1 were normal ranges (BUN 9.0~22.6 mg/dl, creatinine 0.8~1.2 mg/dl, Ca 9.7~12.3 mg/dl, Pi 2.9~4.6 mg/dl), renal failure was not observed. On the 3rd day in group 2, azotemia was arisen from the increasing BUN 83 mg/dl (7~25 mg/dl), creatinine 2.3 mg/dl (0.5~1.4 mg/dl), when executed urine was tested by E.R.D-$screen^{TM}$ test using in the early kidney disease diagnosis, microalbumine state was high positive, and it showed stale delay by using excretory urography (EU). This study demonstrated that acute renal failure by grapes and raisins dependent on food dose, and specific characters of individual.

• Bulletin of the Korean Chemical Society
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• 제27권11호
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• pp.1769-1774
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• 2006

A new liquid chromatographic chiral stationary phase based on (2S,3S)-O,O'-bis-(10-undecenoyl)-N,N'-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butandiol was prepared starting from (2R,3R)-1,4-bis(benzyloxy)-2,3-butanediol. The new chiral stationary phase was applied to the resolution of racemic anilide derivatives of N-acetyl-a-amino acids, 1,1'-bi-2-naphthol and 3,3'-diaryl-1,1'-bi-2-naphthols. The CSP was also applied to the resolution of some chiral drugs including a diuretic, bendroflumethiazide, and non-steroidal anti-inflammatory agents such naproxen and alminoprofen. In every case, the chiral recognition efficiency of the new CSP was quite excellent.

• 한국한의학연구원논문집
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• 제12권1호
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• pp.59-68
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• 2006

The present study was designed to investigate the effects of Ligustici Rhizoma on the expression of genes in the pain model induced by acetic acid. cDNA microarray (GenePlorer TwinChipTM Mouse 7.4K) was used to evaluate the gene expressions. The expressions of 32 genes were up-regulated in the Ligustici Rhizoma-treated group: they include the genes coding Casp6, Hrh3, Basp1, Sprr2h, Zfp131, Copz2, LOC432436, Itpr5, etc. The expressions of 16 genes were down-regulated in the Ligustici Rhizoma-treated group: they include the genes coding Il16, Zfpm1, Cacna2d1, Xpo7, Smpdl3b, Dscr1, Harp, etc. The conclusion is that the expressions of 32 genes were up-regulated and the expressions of 16 genes were down-regulated in Ligustici Rhizoma-treated group.

• 한국한의학연구원논문집
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• 제17권2호
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• pp.47-56
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• 2011

Objective : This study reviews the articles about 'Side effect' published in the Japanese Journal of Oriental Medicine to better understand about side effects of herbal medication and to encourage clinicians, the authorities and the public to establish side effects reporting system. Method : We searched articles published in the Japanese Journal of Oriental Medicine by using keyword '副作用(Side effect)' in the CiNii. Results : Among the 118 articles collected, 14 are clinical articles about side effect of prescriptions, 13 are reports about side effect of prescriptions presented from Japanese Ministry of Health, Labour and Welfare, 36 are clinical articles about relief of side effects derived from taking western medicine by taking a herbal prescription, 8 are studies about the effect of a herbal prescription combined with western medicine or comparative studies between a herbal prescription and western medicine, and so on. Conclusions : Lots of articles deal with side effects of Aconiti Lateralis Radix Preparata, Bupleuri Radix and so on. When side effects occurred, removing a certain herbal drug or quitting a herbal prescription is helpful to relieve or disappear the side effects. And Side effects reporting system should be established to guide safe medication use and treatment for patients. In order to establish side effects reporting system, the standardization of herbal drugs is needed.

• 한국산학기술학회논문지
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• 제15권2호
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• pp.1051-1058
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• 2014

본 논문에서는 PSPICE 프로그램을 이용하여 멤리스터 소자의 전기적 특성을 해석하였다. 멤리스터의 PSPCE 회로해석을 위한 모델링을 제안하고, 멤리스터의 전류-전압 특성을 분석하였고, 멤리스터의 입력전압에 따른 비선형 저항의 변화를 DC해석과 과도해석을 통하여 확인하였다. 또한, 멤리스터 저항의 직렬과 병렬연결에 따른 특성변화를 보았다. 한편, 멤리스터와 커패시터로 이루어진 M-C 회로를 구성하여 충전과 방전특성의 변화를 종래의 R-C회로와 비교분석하였다. 250 Hz의 구형파 입력신호 인가 시, 멤리스터-커패시터 회로의 경우에, 상승시간(Tr) 0.58 ms, 하강 시간 (Tf) 1.6 ms, 지연시간 0.6ms를 나타내었다.

• 자원리싸이클링
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• 제20권2호
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• pp.45-53
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• 2011

본 연구에서는 다양한 방법들을 이용하여 태양전지 폐 모듈로부터 태양전지의 주요 구성요소인 실리콘과 강화유리를 회수하는 연구를 수행하였다. 강화유리는 유기용매를 사용하여 회수하였고, EVA수지는 열처리를 통하여 완전히 제거하였다. 실리콘은 계면 활성제를 첨가한 혼산용액을 이용하여 표면물질을 제거하고 회수하였다. 90%이상의 높은 실리콘 회수율을 얻었다. 본 연구에 의하여 얻어진 강화유리와 실리콘은 태양전지 모듈의 원료로 재활용되어 실리콘 공급부족 문제해결, 태양전지 제조원가 및 폐기물 처리비용 절감에 기여할 것으로 기대된다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2017년도 학술발표회
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• pp.411-411
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• 2017

유역 내 발생하는 강우의 공간적인 분포는 인접성 및 거리에 따라 달라질 수 있다. 공간자기상관 분석은 공간단위(유역 또는 행정구역)의 변수(강수 등)가 주변지역과 갖는 관계를 통해 얼마나 분산되어 있는지 혹은 군집되어 있는지를 판별하는 기법으로 최근 많은 연구에서 활성화 되고 있다. 본 연구에서는 낙동강유역을 대상으로 1980~2000년까지 20개년의 기상청을 통해 수집한 강우자료와 CMIP5(Coupled Model Intercomparison Project Phase 5)에서 제공하는 기후변화 자료 중 가용할 수 있는 20개 모델의 강우를 수집하였다. 기후변화 자료는 정상성 분위사상법으로 지역오차보정을 실시하고 불확실성을 저감하고자 베이지안 모델 평균기법을 통해 새로운 시계열을 생성하였다. 생성된 시계열의 공간적인 분포를 정량적으로 평가하고자 중권역별 공간자기상관 분석을 수행하였다. 대부분의 연구에서는 GIS를 활용하여 정성적으로 강우의 분포를 나타내고 있지만 본 연구에서는 공간단위의 인접성 또는 거리에 따른 척도를 기반으로 공간자기상관을 탐색할 수 있는 Moran's I와 LISA(Local Indicators of Spatial Association)기법을 적용하였다. Moran's I는 전체 연구지역에 대한 관계를 하나의 값으로 보여주는 전역적인 기법이며, LISA는 상대적으로 넓은 지역을 국지적으로 구분하여 특정지역에 대한 Hot spot 및 Cold spot을 통해 공간자기상관 정도를 나타내는 국지적인 기법이다. 두 기법을 적용하기 위하여 인접성 기반의 공간매트릭스를 산정하고 계절별 관측값과 베이지안 앙상블 강우의 Moran's I 및 LISA 분석을 실시하였다. 관측자료와 베이지안 앙상블 강우의 분석결과가 매우 유사하게 나타남으로써 베이지안 앙상블 강우의 공간적인 분포가 관측강우를 충분히 재현하고 있다고 판단된다.