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Protective effect of matcha green tea (Camellia sinensis) extract on high glucose- and oleic acid-induced hepatic inflammatory effect (고당 및 올레산으로 유도된 간세포에서의 염증반응에 대한 말차(Camellia sinensis) 추출물의 보호효과)

  • Kim, Jong Min;Lee, Uk;Kang, Jin Yong;Park, Seon Kyeong;Shin, Eun Jin;Moon, Jong Hyun;Kim, Min Ji;Lee, Hyo Lim;Kim, Gil Han;Jeong, Hye Rin;Park, Hyo Won;Kim, Jong Cheol;Heo, Ho Jin
    • Korean Journal of Food Science and Technology
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    • v.53 no.3
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    • pp.267-277
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    • 2021
  • To evaluate hepatoprotective effects, the antioxidant capacities of matcha green tea extract (Camellia sinenesis) were compared to those of green leaf tea and the anti-inflammatory activities in HepG2 cells were investigated. Evaluation of the total phenolic and total flavonoid content, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, and inhibitory effect on lipid peroxidation indicated that the aqueous extract of matcha green tea presented significant catechin content and antioxidant capacity compared to those of green leaf tea. In addition, the extract had considerable inhibitory effects on α-glucosidase, α-amylase, and advanced glycation end-products. The matcha green tea extract significantly increased cell viability and reduced reactive oxygen species in H2O2- and high-glucose-treated HepG2 cells. Furthermore, in response to oleic acid-induced HepG2 cell injury, treatment with matcha green tea aqueous extract inhibited lipid accumulation and regulated the expression of inflammatory proteins such as p-JNK, p-Akt, p-GSK-3β, caspase-3, COX-2, iNOS, and TNF-α. Matcha green tea could be used as a functional material to ameliorate hepatic lipid accumulation and inflammation.

Bioactive compounds in food for age-associated cognitive decline: A systematic review (인지기능 개선을 위한 식품유래 생리활성소재에 대한 체계적 문헌고찰)

  • Kang, Eun Young;Cui, Fengjiao;Kim, Hyun Kyung;Go, Gwang-woong
    • Korean Journal of Food Science and Technology
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    • v.53 no.3
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    • pp.278-289
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    • 2021
  • The rapid aging of society has led to a surge in cognitive dysfunction in the elderly. As there is limited evidence for the development of dementia in medicine, a shift in focus on prevention strategies using bioactive compounds in food is required. This systematic review evaluated the effects of various bioactive compounds on age-associated cognitive decline. The literature was searched for terms related to bioactive compounds in cognitive decline and article selection was limited to clinical randomized controlled trials for a single bioactive compound. We identified 21 studies that evaluated the strength of the evidence. ω-3 fatty acids and vitamin B presented a strong evidence level, whereas vitamin D and E, anserine/carnosine, and chromium were defined as having moderate levels of evidence. ω-3 fatty acids relieved cognitive decline and reduced amyloid β-related protein accumulation. Vitamin B decreased homocysteine levels, which is accompanied by alleviation of cognitive function. In conclusion, ω-3 and vitamin B have the potential to improve age-associated cognitive decline.

A new glimpse on the foundation of the Bronze Age concept in Korean archaeology (한국 고고학 성립 시기 청동기 연구에 대한 새로운 인식 - 윤무병(1924~2010)의 연구를 중심으로 -)

  • KANG, Inuk
    • Korean Journal of Heritage: History & Science
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    • v.54 no.2
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    • pp.154-169
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    • 2021
  • The establishment of the Bronze Age is one of the most important achievements suggested by Korean archaeology shortly after liberation. There is no doubt that Moo-Byung Yoon is the representative figure, who refuted the ambiguous Eneolithic age (金石倂用期) created by Japanese scholars and settled the concept of the Bronze Age. In this article, the author takes a new look at Yoon's institutional role in studying the Bronze Age in Korea. Until now, Yoon's representative achievement has been his typology of the Slender dagger of the Korean Peninsula. However, it is not less important that Yoon also established the Bronze Age concept with the excavation of a dolmen and a Bronze Age subterranean dwelling in Oksok-ni, Paju during the 1960s. Of course, it was not a personal assignment for Yoon. He was aided by Prof. Kim Won-Yong's work, who had introduced newly excavated materials from North Korea and China; these materials gave some insight for establishing the Bronze Age concepts in the 1960 and 1970s. Kim's suggestion about the possibility of a Korean Bronze Age led to Yoon's refined typological study on Korea's bronze wares. However, Yoon's excessive schematic classification of artifacts and reliance on the Japanese chronology became an obstacle for making the Korean Bronze Age isolated from East Asia. As a result, it is regrettable that his research led to the "cultural lag" phenomenon of Bronze Age research. Meanwhile, Japanese archaeology, which had influenced Yoon, also faced a major change. In 2003, the Japanese archaeological community revised the Yayoi culture's beginning around the 1,000 BC. This means a shift in the perception that we should understand Japan's Bronze Age in the context of the East Asian continent. Of course, it is not appropriate to reevaluate or denigrate Yoon's research from the current view. Rather, it is necessary to recognize the limitations of Yoon's time and present a new path to research by combining the archaeological tradition of refining research on the relics he maintained with a new chronological view and a macro view of East Asian archaeology. This is why we should take a new glimpse into Yoon's research.

Research Trends in Hybrid Cross-Laminated Timber (CLT) to Enhance the Rolling Shear Strength of CLT (CLT의 rolling shear 향상을 위한 hybrid cross laminated timber 연구 동향)

  • YANG, Seung Min;LEE, Hwa Hyung;KANG, Seog Goo
    • Journal of the Korean Wood Science and Technology
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    • v.49 no.4
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    • pp.336-359
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    • 2021
  • In this study, hybrid CLT research and development trends were analyzed to improve the low rolling shear strength of CLT, a large wooden panel used in high-rise wooden buildings. Through this, basic data that can be used in research and development directions for localization of CLT were prepared. As a way to improve the low rolling shear strength, the use of hardwood lamina, the change of the lamina arrangement angle, and the use of structural composite materials are mainly used. Rolling shear strength and shear modulus of hardwood lamina are more than twice as high as softwood lamina. It confirmed that hardwoods can be used and unused species can be used. Rolling shear strength 1.5 times, shear modulus 8.3 times, bending stiffness 4.1 times improved according to the change of the layer arrangement angle, and the CLT strength was confirmed by reducing the layer arrangement angle. Structural wood-based materials have been improved by up to 1.35 times MOR, 1.5 times MOE, and 1.59 times rolling shear strength when used as laminas. Block shear strength between the layer materials was also secured by 7.0 N/mm2, which is the standard for block shear strength. Through the results of previous studies, it was confirmed that the strength performance was improved when a structural wood based materials having a flexural performance of MOE 7.0 GPa and MOR 40.0 MPa or more was used. This was determined based on the strength of layered materials in structural wood-based materials. The optimal method for improving rolling shear strength is judged to be the most advantageous application of structural wood based materials with strength values according to existing specifications. However, additional research is needed on the orientation of CLT lamina arrangement according to the fiber arrangement of structural wood-based materials, and the block shear strength between lamina materials.

Biological characteristics of Phanuromyia ricaniae(Hemiptera: Platygastroidea), an egg parasitoid of Ricania sublimata (Hemiptera: Ricaniidae) (갈색날개매미충 알 기생봉인 날개매미충알벌(Phanuromyia ricaniae)의 생물 특성)

  • Jeon, Sung-Wook;Kim, Kwang-Ho;Lee, Gwan-Seok;Seo, Bo Yoon;Kim, Ji Eun;Kang, Wee Soo;Cho, Jum Rae
    • Korean Journal of Environmental Biology
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    • v.38 no.4
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    • pp.586-593
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    • 2020
  • This study was conducted to investigate the biological characteristics of Phanuromyia ricaniae (Hemiptera: Platygastroidea), an egg parasitoid of Ricania sp. (Hemiptera: Ricaniidae) as a biological control agent to control Ricania sublimata. The developmental period of P. ricaniae was 3.8 days for eggs, 11.1 days for larvae, and 16.3 days for pupae at 25℃, and 3.4 days for eggs, 7.8 days for larvae, and 15.3 days for pupae at 30℃. Except for the larval stage, the developmental periods were not significantly different, but the egg-to-pupa period at 30℃ was significantly shorter than that at 25℃. P. ricaniae emerged at the photophase in 24 hours, but not at the scotophase. A higher emergence rate (34.5%) was seen from 10:00 to 12:00 after the lights were turned. The female-to-male ratio of P. ricaniae was 3:1. The longevity of P. ricaniae adults was 49.0 days for females and 44.0 days for males at 20℃, 27.6 days for females and 28.4 days for males at 25℃, and 18 days for females and 14.0 days for males at 30℃. Its longevity at a low temperature (20℃) was longer than that at higher temperatures (25 and 30℃). Adult females laid eggs during all days except from 00:00-02:00 (scotophase time). The ovipositional distribution rate was 26.1% from 20:00 to 22:00, which was the peak, and the next peak was 15.7% at 10:00 to 12:00. P. ricaniae showed arrhenotokous parthenogenesis in which unfertilized eggs develop into males. Therefore, the results suggest that P. ricaniae may be a biological control agent for R. sublimata.

Growth at Heading Stage of Rice Affected by Temperature and Assessment of the Target Growth Applicable to North Korea for Breeding in South Korea (기온에 따른 벼 출수기 생육 반응 및 남한에서 북한 적응 품종 육성을 위한 출수기 목표 생장량 추정)

  • Yang, Woonho;Choi, Jong-Seo;Lee, Dae-Woo;Kang, Shingu;Lee, Seuk-ki;Chae, Mi-Jin
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.23 no.2
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    • pp.108-121
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    • 2021
  • Field studies at Suwon, Cheorwon, and Jinbu were carried out to determine the relationship between mean temperature from transplanting to heading (MT) and growth at heading stage of rice. P lant height (P H) and dry weight (DW) at heading stage were significantly correlated with MT, showing second degree polynomials. The optimal temperatures for PH and DW were 23.2 ℃ and 22.8 ℃, respectively. Little differences in rice growth among soils collected from the experimental sites and the temperature-response in a phytotron study supported that MT was the main determinant of the growth shown in the field study. Though number of days to heading increased as MT decreased, cumulative temperatures (CT) affected by sites and MT for given varieties were fairly constant. When applying specific CT for each of the varieties to the temperature in North Korea, (1) five regions (Kaesong, Haeju, Sariwon, Nampo, Pyongyang) were suitable for early to mid-maturing varieties and (2) 14 regions (Yongyon, Singye, Anju, Kusong, Sinuiju, Changjon, Wonsan, Hamhung, Pyonggang, Yangdok, Huichon, Supung, Sinpo, Kanggye) were suitable only for early-maturing varieties. In (1) regions, the similar extent of growth with that in Suwon could be achieved when mid-maturing varieties grown in Suwon are cultivated. Among (2) regions, early-maturing varieties are expected to demonstrate the similar extent of growth with that in Cheorwon in 9 regions except Hamhung, Kanggye, Pyonggang, Yangdok, and Sinpo. For Hamhung and Kanggye, the target PH was assessed as 4cm higher than that shown in Cheorwon. P lant height of 8-14cm and DW of 2-4g per hill greater than those shown in Cheorwon were the target growth for P yonggang, Yangdok, and Sinpo to attain the similar amount of growth with that in Cheorwon. It is suggested that rice varieties for North Korea could be bred by adjusting the target growth at the breeding sites in South Korea.

Effect of Nutrient Solution Strength and Duration of Nutrient Starvation on Growth and Flowering of Two Strawberry Cultivars (양액 강도와 공급 중단 시기에 따른 삽목번식한 2품종 딸기의 생장과 개화 반응)

  • Kang, Dong Il;Jeong, Hai Kyoung;Park, Yoo Gyeong;Hwang, Seung Jae;Jeong, Byoung Ryong
    • Journal of agriculture & life science
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    • v.53 no.4
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    • pp.19-28
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    • 2019
  • This study was conducted to investigate the effect of nutrient solution strength and duration of nutrient starvation on the growth and development of strawberry (Fragaria x ananassa Duch.) 'Maehyang' and 'Sulhyang' at the flowering stage. Cuttings of runner plants were stuck on November 23th, 2017 and were covered with a layer of black plastic film to block light from penetrating and keep the relative humidity high. The black plastic film was removed after 16 days and rooted plants were cultivated for one month with irrigation of water. The Yamazaki nutrient solution with an electrical conductivity (EC) of 1.85 or 3.71 dS·m-1 (1x or 2x ionic strength, respectively) and pH 5.55 was fed to plants after either 0 (control), 1, 3 or 5 weeks of nutrient starvation to the end of experiment. Plant height in both cultivars decreased gradually with the increase in duration of nutritional starvation. The earlier the nutritional starvation started, the smaller the shoot fresh weight of 'Maehyang'. Hence the greatest shoot fresh weight was obtained in the control which was supplied with the nutrient solution continuously. Shoot fresh weight of 'Sulhyang' was the greatest in 1x ionic strength and one week of nutrient starvation before planting. Although number of flowers on the first flower cluster of 'Maehyang' and 'Sulhyang' showed no significant differences, 'Maehyang' had the greatest number of flowers in the 2x ionic strength solution and one week of nutrient starvation before planting, while 'Sulhyang' had that in the 1x ionic strength treatment. These results suggest that it is considered effective to supply a nutrient solution at a low concentration for a short period of time for increasing the number of flower differentiated on the first flower cluster in both cultivars.

Association between Medial Temporal Atrophy, White Matter Hyperintensities, Neurocognitive Functions and Activities of Daily Living in Patients with Alzheimer's Disease and Mild Cognitive Impairment (알츠하이머병 및 경도인지장애 환자에서 내측두엽 위축, 대뇌백질병변, 신경인지기능과 일상생활 수행능력과의 연관성)

  • An, Min hyuk;Kim, Hyun;Lee, Kang Joon
    • Korean Journal of Psychosomatic Medicine
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    • v.29 no.1
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    • pp.67-76
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    • 2021
  • Objectives : The aim of this study was to compare activities of daily living (ADLs) according to degenerative changes in brain [i.e., medial temporal lobe atrophy (MTA), white matter hyperintensities] and to examine the association between neurocognitive functions and ADLs in Korean patients with dementia due to Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods : Participants were 111 elderly subjects diagnosed with AD or MCI in this cross-sectional study. MTA in brain MRI was rated with standardized visual rating scales (Scheltens scale) and the subjects were divided into two groups according to Scheltens scale. ADLs was evaluated with the Korean version of Blessed Dementia Scale-Activity of daily living (BDS-ADL). Neurocognitive function was evaluated with the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease assessment packet (CERAD-K). Independent t-test was performed to compare ADLs with the degree of MTA. Pearson correlation and hierarchical multiple regression analyses were performed to analyze the relationship between ADLs and neurocognitive functions. Results : The group with high severity of the MTA showed significantly higher BDS-ADL scores (p<0.05). The BDS-ADL score showed the strongest correlation with the word list recognition test among sub-items of the CERAD-K test (r=-0.568). Findings from the hierarchical multiple regression analysis revealed that the scores of MMSE-K and word list recognition test were factors that predict ADLs (F=44.611, p<0.001). Conclusions : ADLs of AD and MCI patients had significant association with MTA. Our study, which identifies factors correlated with ADLs can provide useful information in clinical settings. Further evaluation is needed to confirm the association between certain brain structures and ADLs.

Automatic Speech Style Recognition Through Sentence Sequencing for Speaker Recognition in Bilateral Dialogue Situations (양자 간 대화 상황에서의 화자인식을 위한 문장 시퀀싱 방법을 통한 자동 말투 인식)

  • Kang, Garam;Kwon, Ohbyung
    • Journal of Intelligence and Information Systems
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    • v.27 no.2
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    • pp.17-32
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    • 2021
  • Speaker recognition is generally divided into speaker identification and speaker verification. Speaker recognition plays an important function in the automatic voice system, and the importance of speaker recognition technology is becoming more prominent as the recent development of portable devices, voice technology, and audio content fields continue to expand. Previous speaker recognition studies have been conducted with the goal of automatically determining who the speaker is based on voice files and improving accuracy. Speech is an important sociolinguistic subject, and it contains very useful information that reveals the speaker's attitude, conversation intention, and personality, and this can be an important clue to speaker recognition. The final ending used in the speaker's speech determines the type of sentence or has functions and information such as the speaker's intention, psychological attitude, or relationship to the listener. The use of the terminating ending has various probabilities depending on the characteristics of the speaker, so the type and distribution of the terminating ending of a specific unidentified speaker will be helpful in recognizing the speaker. However, there have been few studies that considered speech in the existing text-based speaker recognition, and if speech information is added to the speech signal-based speaker recognition technique, the accuracy of speaker recognition can be further improved. Hence, the purpose of this paper is to propose a novel method using speech style expressed as a sentence-final ending to improve the accuracy of Korean speaker recognition. To this end, a method called sentence sequencing that generates vector values by using the type and frequency of the sentence-final ending appearing in the utterance of a specific person is proposed. To evaluate the performance of the proposed method, learning and performance evaluation were conducted with a actual drama script. The method proposed in this study can be used as a means to improve the performance of Korean speech recognition service.

Electrochemical Performance of CB/SiOx/C Anode Materials by SiOx Contents for Lithium Ion Battery (SiOx 함량에 따른 CB/SiOx/C 음극재의 전기화학적 특성)

  • Kim, Kyung Soo;Kang, Seok Chang;Lee, Jong Dae;Im, Ji Sun
    • Applied Chemistry for Engineering
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    • v.32 no.1
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    • pp.117-123
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    • 2021
  • In this study, the composite was prepared by mixing SiOx, soft carbon, and carbon black and the electrochemical properties of lithium ion battery were investigated. The content of SiOx added to improve the capacity of the soft carbon anode material was varied to 0, 6, 8, 10, 20 wt%, and carbon black was added as a structural stabilizer for reducing the volume expansion of SiOx. The physical properties of prepared CB/SiOx/C composite were investigated through XRD, SEM, EDS and powder resistance analysis. In addition, the electrochemical properties of prepared composite were observed through the charge/discharge capacity, rate and impedance analysis of the lithium ion battery. The prepared CB/SiOx/C composite had an inner cavity capable of mitigating the volume expansion of SiOx by adding carbon black. The formed internal cavity showed a low initial efficiency when the SiOx content was less than 8 wt%, and low cycle stability when the content of SiOx was less than 20 wt%. The CB/SiOx/C composite containing 10 wt% of SiOx showed an initial discharge capacity of 537 mAh/g, a capacity retention rate of 88%, and a rate of 79 at 2C/0.1C. SiOx was added to improve the capacity of the soft carbon anode material, and carbon black was added as a structural stabilizer to buffer the volume change of SiOx. In order to use the CB/SiOx/C composite as a high-efficiency anode material, the mechanism of the optimal SiOx and the use of carbon black as a structural stabilizer was discussed.