• Journal of Advanced Marine Engineering and Technology
• /
• v.32 no.1
• /
• pp.33-41
• /
• 2008

Bearing damages by shaft misalignment have frequently been happened in marine ships. Specially. after stern tube bearing damage and failure for large crude oil carriers have been reported several times. However. the bearing reaction of the after stern tube bearing cannot be measured by jack-up test due to the hull structure condition. Therefore, when the jack-up test is used for the bearing reaction measurements, the bearing reaction for the after stern tube bearing obtained from the theoretical calculation method have to be used. In this paper, the shaft alignment on the large oil crude carrier is theoretically calculated and the differences between the calculated and actual installed bearing reaction values are compared. The bearing reactions for forward stern tube bearing and intermediate bearing are calculated by the simple formula using the strain gauge bending moments obtained from the measurements. Their reliability is confirmed by comparing the bearing reactions from jack-up test and the bearing reaction for after stern tube bearing is calculated by the same test. Also, the bearing reactions on the after stern tube bearing, forward stern tube bearing and intermediate shaft bearing under all operating conditions are calculated by using the bending moments obtained from the measurements and it is confirmed that the differences of the bearing reaction for all operating conditions are caused from hull deflection. The results of this study should prove useful for the future projects of the alignment calculation including the hull deflection effectiveness.

• Molecules and Cells
• /
• v.38 no.3
• /
• pp.243-250
• /
• 2015

Patterning of the polar axis during the early leaf developmental stage is established by cell-to-cell communication between the shoot apical meristem (SAM) and the leaf primordia. In a previous study, we showed that the DRL1 gene, which encodes a homolog of the Elongator-associated protein KTI12 of yeast, acts as a positive regulator of adaxial leaf patterning and shoot meristem activity. To determine the evolutionally conserved functions of DRL1, we performed a comparison of the deduced amino acid sequence of DRL1 and its yeast homolog, KTI12, and found that while overall homology was low, well-conserved domains were presented. DRL1 contained two conserved plant-specific domains. Expression of the DRL1 gene in a yeast KTI12-deficient yeast mutant suppressed the growth retardation phenotype, but did not rescue the caffeine sensitivity, indicating that the role of Arabidopsis Elongator-associated protein is partially conserved with yeast KTI12, but may have changed between yeast and plants in response to caffeine during the course of evolution. In addition, elevated expression of DRL1 gene triggered zymocin sensitivity, while overexpression of KTI12 maintained zymocin resistance, indicating that the function of Arabidopsis DRL1 may not overlap with yeast KTI12 with regards to toxin sensitivity. In this study, expression analysis showed that class-I KNOX genes were downregulated in the shoot apex, and that YAB and KAN were upregulated in leaves of the Arabidopsis drl1- 101 mutant. Our results provide insight into the communication network between the SAM and leaf primordia required for the establishment of leaf polarity by mediating histone acetylation or through other mechanisms.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.9
• /
• pp.3887-3891
• /
• 2015

Aloe-emodin (1, 8-dihydroxy-3-hydroxyl-methylanthraquinone; AE) and emodin (1,3,8-trihydroxy-6-methylanthraquinone; EM) are anthraquinone derivatives that have been detected in some medical plants and share similar anthraquinone structures. AE and EM have been shown to exhibit anticancer activities in various cancer cell lines; however, the inhibitory effects of these derivatives on the growth of cancer cells were previously reported to be different. Gastric cancer is the second most common cause of cancer cell death worldwide. In the present study, we examined the inhibitory effects of 0.05 mM AE and 0.05 mM EM on the proliferation of the MKN45 human gastric cancer cell line. The proliferation of MKN45 cells was significantly inhibited in AE- and EM-treated groups 24 h and 48 h after treatment. Furthermore, the inhibitory effects of EM were stronger than those of AE. The cell cycle of MKN45 cells were arrested in G0/G1 phase or G0/G1 and G2/M phases by AE and EM, respectively. However, an analysis of intracellular polyamine levels and DNA fragmentation revealed that the mechanisms underlying cell death following cell arrest induced by AE and EM differed.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.9
• /
• pp.3881-3885
• /
• 2015

Obesity markedly increases the risk of colorectal cancer. Recently, the preventive effects of edible mushrooms on triglyceride elevation and visceral fat accumulation have been reported. Here, the effects of Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji) on azoxymethane (AOM)-induced aberrant crypt foci (ACF; precancerous lesions) in the colorectums of mice fed a high-fat diet were examined. Eringi (ER) and Bunashimeji (BU) mushroom powder samples were used. Six-week-old male C57BL/6J mice received an intraperitoneal injection of AOM (10 mg/kg) once a week for two weeks, and were sacrificed and dissected at 6 weeks after the start of the experiment. After the initiation of the experiment, they received a normal diet (ND), high-fat diet (HFD), HFD + ER (1 or 5% of diet), or HFD + BU (1 or 5% of diet). As a result, body and fat weights were significantly lower in the 5% ER and BU groups than in the HFD group. Liver triglyceride levels were also significantly lower in the 5% ER and BU groups. Total liver cholesterol levels were significantly lower in the 5% ER group. The numbers of ACF (especially large ACF) showed strong inhibitory effects in both ER and BU groups. Measurement of the cell proliferation marker Ki-67 labeling index in the colonic mucosa demonstrated more significant suppression in both ER and BU groups than in the HFD group. These results suggest that the simultaneous intake of ER and BU may inhibit colorectal tumorigenesis in HFD-fed mice.

• The Journal of Korean Association of Computer Education
• /
• v.17 no.6
• /
• pp.135-146
• /
• 2014

The study has compared the effects in SNS-utilized instruction that each of self centric activities and social interaction added social activities affected self initiative, attitudes and self efficacy to information technology respectively. The research methods utilized the pre experimental design as nonequivalent experimental group. The data was analyzed by paired t-test and content analysis. The results showed that the SNS class utilized self-centric activities were effective in self-initiative and attitudes toward information technology, while social interaction added social activities were effective in not only self-initiative and the attitudes of information technology but also self efficacy of information technology. And content analysis of the effects of the education showed that information sharing, instancy and accessibility were advantageous but information security and privacy issues were problematic. That is, it was confirmed that when self-centric activities and social interaction activities were practised simultaneously in SNS-utilized instruction, the self initiative which learners planed and executed by themselves, the attitudes and self efficacy of information technology which were able to enhance learning ability and to show satisfaction to individual learning were improved.

• Journal of Fisheries and Marine Sciences Education
• /
• v.25 no.4
• /
• pp.937-957
• /
• 2013

This study was conducted for the purpose of developing the UCC project teaching and learning model based on the rationale which are applicable effectively in the field of university education. Firstly, we have designed the rationale based on the research of documents and preceding researches about teaching method models. Secondly, we have developed the UCC project teaching and learning model. the UCC project teaching and learning model based on the rationale was assessed by the professional formative evaluation group and tested in the field of university education in advance and thereafter. It was finally rectified and supplemented. Particularly, any corrections were to be made repeatedly in the stage of developing of the UCC project. And also, during the assessment and arrangement process, it was designed for the study participants to feel a sense of achievement as learners who combine knowledge and attitudes toward participants'subjects of the curriculum and professional vocational skills by performing the nursing science training scene which could happen in the field. Thirdly, the final version of the UCC project teaching and learning model was verified in its effectiveness by being applied in the field of the nursing science education in the $2^{nd}$ step. As a result, we noticed that learners diverse abilities were improved through systemic process and performing elements such as teaching plan which was needed for designing the UCC project in the field, making storyboard and skills for making video contents. We hope that the UCC project teaching and learning model in this study will be used by the students for designing, developing and utilizing educational UCCs which are necessary in industrial fields and it will contribute for training university students as professionals having the practical skills in the field.

• Nuclear Engineering and Technology
• /
• v.48 no.3
• /
• pp.635-641
• /
• 2016

Because of prohibitive data storage requirements in large-scale simulations, the memory problem is an obstacle for Monte Carlo (MC) codes in accomplishing pin-wise three-dimensional (3D) full-core calculations, particularly for whole-core depletion analyses. Various kinds of data are evaluated and quantificational total memory requirements are analyzed based on the Reactor Monte Carlo (RMC) code, showing that tally data, material data, and isotope densities in depletion are three major parts of memory storage. The domain decomposition method is investigated as a means of saving memory, by dividing spatial geometry into domains that are simulated separately by parallel processors. For the validity of particle tracking during transport simulations, particles need to be communicated between domains. In consideration of efficiency, an asynchronous particle communication algorithm is designed and implemented. Furthermore, we couple the domain decomposition method with MC burnup process, under a strategy of utilizing consistent domain partition in both transport and depletion modules. A numerical test of 3D full-core burnup calculations is carried out, indicating that the RMC code, with the domain decomposition method, is capable of pin-wise full-core burnup calculations with millions of depletion regions.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.145-145
• /
• 2017

Foxglove aphid, Aulacorthum solani (Kaltenbach), is a Hemipteran insect that infected a wide variety of plants worldwide and caused serious yield losses in crops. The objective of this study was to identify the putative genes to foxglove aphid resistance in wild soybean, PI 366121 (Glycine soja Sieb. and Zucc.). One hundred and forty-one F4:8 recombinant inbred lines developed from a cross between susceptible variety, Williams 82 and foxglove aphid resistance wild soybean, PI 366121 were used. The two type of resistance response, antibiosis and antixenosis resistance were evaluated through choice and no-choice test, graded by the degree of total plant damage and primary infestation leaf damage; a genome-wide molecular linkage map was constructed with 29,898 single-nucleotide polymorphism markers utilizing a Axiom(R) 180K soyaSNP array. Using inclusive composite interval mapping analysis for foxglove aphid resistance, one major candidate QTL on chromosome 7 was identified. The major QTL on chromosome 7 showed both antixenosis and antibiosis resistance responses. The newly identified major QTL was consistent with previously reported QTL, Raso2, which showed around 5 times narrow down interval range with 8 candidate genes. Furthermore, total 1,115 soybean varieties including Glycine soja and Glycine max were exposed to germplasm screening, and 31 varieties, which showed significant antibiosis type foxglove aphid resistance were identified. This result could be useful in breeding for new foxglove aphid resistant soybean cultivars and developing novel insecticides.

• The Journal of Internal Korean Medicine
• /
• v.19 no.1
• /
• pp.271-290
• /
• 1998

As a result of investigating the cases of applying Yuk-mi-ji-hwang-tang-kakambang(六味地黃湯加減方) to treating dementia, the following results are obtained. 1. Yuk-mi-ji-hwang-tang-kakambang(六味地黃湯加減方)is applied to anapladementia. 2 Yuk-mi-ji-hwang-tang-kakambang(六味地黃湯加減方) is also applied to treating the dementia due to congenital weakness and defficiencies of the Liver and Kidney, the Spleen and Kidney. 3. To cure congenital weakness, Yuk-mi-ji-hwang-tang(六味地黃湯), Jwa-kwi-hwan(左歸丸), Bo-sin-ik-su-tang(補腎益髓湯) and Chil-bok-eum-kakam(七福飮加減) which can bo-sin-ik-jeong(補腎益精) sung-noi-ik-ji(醒腦益智), for the defficiencies of liver and kidney, Jwa-kwi-hwan-kakam(左歸丸加減), Woo- kwi-eum-kakam(左歸飮加減) and Ki-kuk-ji-hwang-tang-hap-jng-ji-tang-kakam(杞菊地黃湯合定智湯加減) which can bo-ik- kan-sin(補益肝腎) jeon-jeong-gun-noi(塡精健腦) and for the defficiencies of spleen and kidney, Hwan-so-dan-kakam(還少丹加減) and Kum-kwe-shin-ki-hwan-kakam(金궤腎氣丸加減) which can bo-sin-gun-bi(補腎健脾) ik-gi-sang-jeong(益氣生精) gun-noi-sang-su(健腦生髓) 4. Won-Ji(遠志) and Suk-chang-po(石菖蒲) which can sung-sin-ga-gu(醒神開竅) are added to yuk-mi-ji-hwang-tang(六味地黃湯).

• The Journal of Internal Korean Medicine
• /
• v.40 no.6
• /
• pp.1202-1209
• /
• 2019

Objectives: The purpose of this study was to confirm the effects of an auricular acupressure (AA) program for smoking cessation in high school students from 2015 to 2017. Methods: The study investigated 12 high school students who had been smokers. Subjects were treated for three years. Each program was composed of five AA treatments. Average daily smoking and adverse reactions were checked for one week before each procedure. The AA was administered weekly at the endocrine point, lung point, throat point, nasal fossae point, bronchial tube point, and mouth point. Results: The mean number of cigarettes smoked per day after each year of treatment significantly decreased from 5.33±3.58 to 3.54±2.08 in 2015 (p=0.046). However, it increased from 5.75±2.30 to 6.00±3.61 in 2017 (p=0.80). The number of cigarettes smoked before treatment was found to be higher than the number of cigarettes after treatment in the previous year. No significant results were obtained from analysis of the change in the amount of smoking within each year. Conclusion: Social influence, such as the subject's academic stress and peer relationships, may have been a major factor in the change in the amount of smoking. Although the AA did not show a strong effect in smoking cessation, it appears to have value as a supplementary means of stopping smoking.