• Title/Summary/Keyword: KRICT

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DOWN-REGULATION OF RAF-1 KINASE IS ASSOCIATED WITH PACLITAXEL RESISTANCE IN HUMAN BREAST CANCER MCF-7/ADR CELLS

  • Lee, Michael;Jung Kwon;Wayne B. Anderson;Chung, Moon-Koo
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.136-136
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    • 2002
  • Experiments were carried out to determine the role of Raf-1 kinase in the development of drug resistance and apoptosis induced by paclitaxel. In the present study, paclitaxel sensitivity, Raf-1 activity and MAPKs activation were compared in 2 cell lines: parental human breast cancer cells and its drug resistant variant (MCF-7/Adr) cells.(omitted)

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Gif-KRICT Biomimetic Oxidation of Cyclohexane: The Influence of Metal Oxides

  • 박애숙;남상성;김성보;이규완
    • Bulletin of the Korean Chemical Society
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    • v.20 no.1
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    • pp.49-52
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    • 1999
  • Various metal oxides such as Fe2O3, FeO, TiO2, MnO2, MoO3, WO3 and ZnO have been used as a catalyst for Gif-KRICT type cyclohexane oxidation. In this reaction, the conversion of cyclohexane to cyclohexanone and cyclohexanol and the selectivity ratio of cyclohexanone to cyclohexanol were greatly affected by the acidity of metal oxides. When metal oxide has more acidic property, the reactivity on oxidation is increased and the formation of cyclohexanone is more favored. From this result, we proposed a new mechanism for the biomimetic Gif-KRICT oxidation system.

Dehydrogenation of Ethylbenzene with Carbon Dioxide as Soft Oxidant over Supported Vanadium-Antimony Oxide Catalyst

  • Hong, Do-Young;Vislovskiy, Vladislav P.;Park, Sang-Eon;Park, Min-Seok;Yoo, Jin-S.;Chang, Jong-San
    • Bulletin of the Korean Chemical Society
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    • v.26 no.11
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    • pp.1743-1748
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    • 2005
  • This work presents that carbon dioxide, which is a main contributor to the global warming effect, could be utilized as a selective oxidant in the oxidative dehydrogenation of ethylbenzene. The dehydrogenation of ethylbenzene over alumina-supported vanadium-antimony oxide catalyst has been studied under different atmospheres such as inert nitrogen, steam, oxygen or carbon dioxide as diluent or oxidant. Among them, the addition of carbon dioxide gave the highest styrene yield (up to 82%) and styrene selectivity (up to 97%) along with stable activity. Carbon dioxide could play a beneficial role of a selective oxidant in the improvement of the catalytic behavior through the oxidative pathway.

Colloidal Synthesis of Octahedral Shaped PbSe Nanocrystals from Lead Oleate and Se : Temperature Effect

  • Gokarna, Anisha;Jun, Ki-Won;Khanna, P.K.;Baeg, Jin-Ook;Seok, Sang-Il
    • Bulletin of the Korean Chemical Society
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    • v.26 no.11
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    • pp.1803-1806
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    • 2005
  • Formation of octahedral shaped PbSe quantum dots at higher synthesis temperature is being reported in this paper. The synthesis includes the reaction between lead oleate and trioctylphosphine selenide under inert gas conditions to produce PbSe. TEM, SEM, XRD and EDS were used to characterize the samples. The SEM exhibited the formation of spherical shaped nanocrystals at temperature below 140 ${^{\circ}C}$ and octahedral shaped nanoparticles at higher temperatures. Moreover, the TEM also showed the well resolved (111) lattice fringes proving that the nanocrystals were crystalline in nature. Synthesis of highly pure PbSe nanocrystals was another interesting aspect of this research.

Inhibition of methane formation and improvement of $H_2$ production by adding nitrate to anaerobic reactor

  • Kim, Jeong-Ok;Kim, Yong-Hwan;Ryu, Jeong-Yong;Song, Bong-Keun;Kim, In-Ho
    • 한국생물공학회:학술대회논문집
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    • 2003.10a
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    • pp.129-134
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    • 2003
  • Anaerobic hydrogen production was executed using mixed anaerobic sludge. pH control (pH $5.5^{\sim}6.2)$ and heat treatment of anaerobic sluge at $92^{\circ}C$ was not effective for repressing the methane formation. The addition of $nitrate(500^{\sim}2,000\;mg/L\;KNO_3)$ made it possible to repress the methane formation, which resulted in the improvement of hydrogen production. By using SEM(Scanning Electron Microscope), less methane forming microbial with spagetti shape was observed when nitrate was supplied to anaerobic reactor.

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Oral Acute and Subacute Toxicity studies of Captopril(SR Tablet 25mg) in SD Rats.

  • Shin, Chun-Chul;Song, Si-Whan;Kang, Boo-Hyun;Kim, Eun-Joo;Chi, Heung-Woo;Lee, Kyou-Heung;Paik, Woo-Hyun
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.248-248
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    • 1996
  • 경구투여급성독성시험 : 암수동물의 모든 투여군에서 시험물질투여에 의한 일반증상, 체중변화 및 육안적 부검소견은 관찰되지 않았으며. 따라서 반수치사량(LD$_{50}$)은 암수동물의 경우 5000mg/kg이상이었다. 경구투여아급성독성시험 : SD랫트의 암수 동물에 있어서 Captopril(SR Tablet 25mg)의 2000mg/kg 용량은 확실중독량에 해당되며, 무영향량(NOEL)은 220mg/kg용량이라고 사료되었다.

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Development of Decolorizing Method for Color Ledger (색지 폐지의 탈색에 의한 표백펄프의 재생방법)

  • Yoon, Byoung-Tae;Ryu, Jeong-Yong;Shin, Jong-Ho;Song, Bong-Keun;Kim, Tae-Joon;Jeon, Yang
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.32 no.2
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    • pp.45-50
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    • 2000
  • This study was to get the optimum conditions on bleaching by mixing of various colored ledgers with white ledger by 50:50 ratio. This bleaching was carried out by two steps, reductive-oxidative process was shown a better brightness compared to oxidative-reductive one. Especially, in reductive bleaching using sodium hydrosulfite, the aging temperature should keep above 6$0^{\circ}C$ irrespective of aging time, alkaline condition was more effective than acid one. Final brightness after bleaching and feinting was obtained over 78% to be used by the raw pulp of tissue.

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White Light Emitting Diodes for Illumination

  • Choi, Kyoung-Jae;Park, Joung-Kyn;Kim, Kyung-Nam;Kim, Chang-Hae;Kim, Ho-Kun
    • 한국정보디스플레이학회:학술대회논문집
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    • 2006.08a
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    • pp.1090-1092
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    • 2006
  • There is provided white light illumination system including a radiation source, a first luminescent material having a peak emission wavelength of about 575 to about 620 nm, a second luminescent material having a peak emission wavelength of about 495 to about 550 nm, which is different from the first luminescent material and a third luminescent material having a peak emission wavelength of about 420 to about 480 nm, which is different from the first and second luminescent materials. The LED may be a UV LED and the luminescent materials may be a blend of three phosphors. A human observer perceives the combination of the blue, green and red phosphor emissions as white light.

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CNT Emitter Coated with Nanoparticles for FED Application

  • Kim, Jong-Ung;Lee, Jung-A;Ryu, Byong-Hwan;Kim, In-Ho;Moon, Hee-Sung;Kim, Jae-Myeong;Choi, Young-Min
    • 한국정보디스플레이학회:학술대회논문집
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    • 2006.08a
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    • pp.1198-1201
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    • 2006
  • Carbon nanotubes (CNTs) have used as an electron field emitter of the field emission display (FED) due to their characteristics of high-electron emission, rapid response and low power consumption. However, to commercialize the FED with CNT emitter, some fundamental problems regarding life time and emission efficiency have to be solved. In this study, we investigated the metal coated CNT as a field emitter on which metal nanoparticles were coated by chemical modification. Metal nanoparticles, such as Ru, Pd, were synthesized by solution reduction method. The size of the metal nanoparticle has the range of 2 - 5 nm. Surface was modified chemically with the use of ionic surfactant which changed the surface charge of nanoparticles.

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