• Title/Summary/Keyword: KRICT

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Antitumor Agent from the Rhizome of Anemarrhena asphodeloides (지모(知母)의 항암활성성분에 관한 연구)

  • Lee, Seung-Ho;Ryu, Shi-Yong;Choi, Sang-Un;No, Zae-Sung;Kim, Sung-Ki;Lee, Chong-Ock;Ahn, Jong-Woong
    • Korean Journal of Pharmacognosy
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    • v.26 no.1
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    • pp.47-50
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    • 1995
  • EtOAc soluble part of MeOH extract of Anemarrhena asphodeloides rhizome was evaluated for the cytotoxicity against the five kinds of human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF498 and HCT15) in vitro. Bioassay-guided fractionation of EtOAc soluble part led to the isolation of active compound which was identified as timosaponin A-III showed potent cytotoxic activity, but its genin, sarsasapogenin, did not show cell growth inhibition.

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Reference Values of Organ Weights in Sprague-Dawley Rats (Ktc: Sprague-Dawley 랫드의 장기중량치의 자료분석)

  • Kang, Boo-Hyon;Kim, Il-Hwan;Kim, Yong-Bum;Kim, Young-Hee;Lee, Hyun-Sook;Ha, Chang-Su
    • Korean Journal of Veterinary Pathology
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    • v.5 no.2
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    • pp.39-42
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    • 2001
  • A reference range data base containing organ weight values on animals used in 4 week and 13 week toxicity tests is described. Data listed include the values of minimum, maximum, mean and standard deviation for each of the following organ weights. Organs: Brain, heart, liver, spleen, kidney, adrenal gland, testis, ovary. This study was undertaken to determine organ weight reference values of Ktc: SD rats

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