• 한국산학기술학회논문지
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• 제16권11호
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• pp.7285-7292
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• 2015

본 연구의 목적은 생체역학적 변인을 근거로 하여 후진보법의 전방향 보행(댄스보행)이 후방보행처럼 재활과 걷기운동으로써의 가능성을 규명하는 것이다. 실험대상자는 13명의 여성댄스 전문가로 자료수집을 위하여 12대의 적외선카메라와 2대의 지면반력기가 동조되어 사용되었다. 연구결과에 따르면 댄스보행의 보속, 활보장과 양 하지지지기시간은 후방보행보다 크고, 활보폭은 작았으며 관절각범위, 관절모멘트와 관절파워의 최대치 출현 빈도에서 댄스보행이 후방보행보다 더 많았다. 이러한 결과들은 댄스보행이 재활과 걷기운동에 후방보행에 버금가는 훌륭한 도구임을 판단하는데 충분하다.

• 한국운동역학회지
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• 제25권2호
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• pp.175-182
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• 2015

Objective : The purpose of this study was to investigate difference in fascicle behavior of the medial gastrocnemius during the locomotion with varying intensities, such as gait and one-legged and two-legged vertical jumping. Methods : Six subjects (3 males and 3 females; age: $27.2{\pm}1.6yrs.$, body mass: $62.8{\pm}9.8kg$, height: $169.6{\pm}8.5cm$) performed normal gait (G) at preferred speed and maximum vertical jumping with one (OJ) and two (TJ) legs. While subjects were performing the given tasks, the hip, knee and ankle joint motion and ground reaction force was monitored using a 8-infrared camera motion analysis system with two forceplates. Simultaneously, electromyography of the triceps surae muscles, and the fascicle length of the medial gastrocnemius were recorded using a real-time ultrasound imaging machine. Results : Comparing to gait, the kinematic and kinetic parameters of TJ and OJ were found to be significantly different. Along with those parameters, change in the medial gastrocnemius (MG) muscle-tendon complex (MTC) length ($50.57{\pm}6.20mm$ for TJ and $44.14{\pm}5.39mm$ for OJ) and changes in the fascicle length of the MG ($18.97{\pm}3.58mm$ for TJ and $20.31{\pm}4.59mm$ for OJ) were observed. Although the total excursion of the MTC and the MG fascicle length during the two types of jump were not significantly different, however the pattern of length changes were found to be different. For TJ, the fascicle length maintained isometric longer during the propulsive phase than OJ. Conclusion : One-legged and two-legged vertical jumping use different muscle-tendon interaction strategies.

• Asian Pacific Journal of Cancer Prevention
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• 제17권9호
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• pp.4217-4222
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• 2016

Purpose: To compare the expression level of CK 15 in normal esophageal and esophageal squamous-cell carcinoma (ESCC) tissues and analyse possible functions of CK15 in occurrence and development. Materials and Methods: Immunohistochemistry was used to compare CK14, CK15 and proliferating cell nuclear antigen (PCNA) expression levels in ESCCs. Expression level of CK15 was also assessed by Western blotting. In addition, levels of CK15, cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) and PCNA were detected in serum by enzymelinked immunosorbent assay (ELISA) and chemiluminescence methods. Relationships between clinicopathological parameters and CK14 and CK15 expression were then analyzed. Results: According to immunohistochemistry, in esophageal and intraepithelial neoplasia (SIN) tissues, the expression of CK14, CK15 and PCNA localized to basal layer of the epithelium. CK14 and CK15 levels were higher in normal esophageal squamous epithelial tissue than in SIN and ESCC, and greater in highly differentiated than poorly differentiated carcinoma tissue. By Western blotting, we found more pronounced expression of CK15 in normal esophageal tissue, compared with carcinoma tissue. The specificity of changed CK15 and CYFRA21-1 expression was respectively 90.0% and 96.7% in serum of ESCC patients. Joint detection could improve the sensitivity of esophageal carcinoma diagnosis. Relationships between CK14, CK15 expression and clinical parameters were not statistically significant (P>0.05). Postoperative survival in patients of CK14, CK15 positive expression was longer than with negative expression ($x^2=4.35$, P=0.037; $x^2=9.852$, P=0.002). Conclusions: CK15 expression decreased in esophageal squamous cell carcinoma tissue and serum of esophageal squamous carcinoma patients. We infer that CK15 may play an important role for the occurrence and development of esophageal squamous-cell carcinoma. In the future, CK15 may be used for the diagnosis, treatment and prognostic evaluation of esophageal squamous-cell carcinoma.

• 대한족부족관절학회지
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• 제12권1호
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• pp.1-8
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• 2008

Purpose: To evaluate the value and limitation of modified Mau osteotomy through the review of 30 feet treated by this procedure. Materials and Methods: We retrospectively analyzed 30 cases treated with modified Mau osteotomy since 2002. The mean duration of follow-up was 10 months. We reviewed medical records to describe each case and select several clinical factors which related with surgical procedure and could influence on final results. We measured radiographic parameters such as hallux valgus angle (HVA), intermetatarsal angle (IMA), distal metatarsal articular angle (DMAA), sesamoid position and also assessed clinical outcomes by AOFAS score and satisfaction degrees. Results: The mean preoperative HVA and IMA were $40.4^{\circ}$, $17.4^{\circ}$ and the mean amounts of correction were $31.2^{\circ}$ and $11.5^{\circ}$. Amounts of delayed loss of correction were 16.8% in HVA and 19.2% in IMA. Initial HVA, rotational angle and translation distance of the distal fragment, stability of fixation, first ray instability were revealed as significant factors for the final result from this procedure. DMAA was increased by rotation of the distal fragment and decreased by adding translation on the rotation. Conclusion: Modified Mau osteotomy is an effective procedure to get enough correction. But, it is important to try to avoid excessive rotation of the distal fragment because it may worse joint congruity. It may be worthwhile to pay close attention to the direction of saw and stability of fixation.

• Journal of Korean Neurosurgical Society
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• 제55권5호
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• pp.255-260
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• 2014

Objective : The purpose of this study was to compare the radiological and neurological outcomes between two atlantoaxial fusion method for atlantoaxial stabilization; C1 lateral mass-C2 pedicle screws (screw-rod constructs, SRC) versus C1-2 transarticular screws (TAS). Methods : Forty-one patients in whom atlantoaxial instability was treated with atlantoaxial fixation by SRC group (27 patients, from March 2005 to May 2011) or TAS group (14 patients, from May 2000 to December 2005) were retrospectively reviewed. Numeric rating scale (NRS) for pain assessment, Oswestry disability index (ODI), and Frankel grade were also checked for neurological outcome. In radiologic outcome assessment, proper screw position and fusion rate were checked. Perioperative parameters such as blood loss during operation, operation time, and radiation exposure time were also reviewed. Results : The improvement of NRS and ODI were not different between both groups significantly. Good to excellent response in Frankel grade is shown similarly in both groups. Proper screw position and fusion rate were also observed similarly between two groups. Total bleeding amount during operation is lesser in SRC group than TAS group, but not significantly (p=0.06). Operation time and X-ray exposure time were shorter in SRC group than in TAS group (all p<0.001). Conclusion : Both TAS and SRC could be selected as safe and effective treatment options for C1-2 instability. But the perioperative result, which is technical demanding and X-ray exposure might be expected better in SRC group compared to TAS group.

• Geomechanics and Engineering
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• 제16권1호
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• pp.21-34
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• 2018

Discontinuities considerably affect the mechanical and hydraulic properties of rock mass. These properties of the rock mass are influenced by the geometry of the discontinuities to a great extent. This paper aims to render an account of the geometrical parameters of several discontinuity sets related to the surrounding rock mass of Rudbar Lorestan Pumped Storage Power Plant powerhouse cavern making use of the linear and areal (circular and rectangular) sampling methods. Taking into consideration quite a large quantity of scanline and the window samplings used in this research, it was realized that the areal sampling methods are more time consuming and cost-effective than the linear methods. Having corrected the biases of the geometrical properties of the discontinuities, density (areal and volumetric) as well as the linear, areal and volumetric intensity accompanied by the other properties related to four sets of discontinuities were computed. There is an acceptable difference among the mean trace lengths measured using two linear and areal methods for the two joint sets. A 3D discrete fracture network generation code (3DFAM) has been developed to model the fracture network based on the mapped data. The code has been validated on the basis of numerous geometrical characteristics computed by use of the linear, areal sampling methods and volumetric method. Results of the linear sampling method have significant variations. So, the areal and volumetric methods are more efficient than the linear method and they are more appropriate for validation of 3D DFN (Discrete Fracture Network) codes.

• 한국산학기술학회논문지
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• 제13권4호
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• pp.1460-1465
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• 2012

본 연구에서는 소방배관용 아연도금 강관을 용접하기 위하여 반자동 가스메탈아크용접장치를 개발하고 최적 용접 조건을 확립하고 용접성을 조사하기 위해 보호가스, 전압을 변화시켜 용접시험을 수행하였다. Ar 가스에 $O_2$를 첨가함으로써 미려한 비드외관과 기공률이 감소되었다. 반자동 용접부는 기계적 강도와 용접이음효율이 수동용접부에 비해 약 1.8배 우수하였으며 수압시험에 의해 건전성이 확인되었다. 본 연구에서 개발된 반자동용접장치로 비숙련자도 강관용접이 가능하며 용접결함이 적고 용접생산성을 증대시킬 수 있을 것으로 기대된다.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.320-323
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• 2002

This paper presents a new generation of system for pressure vessel and shipbuilding. Typical pressure vessel and ship building weld joint preparations are either traditional V, butt, fillet grooves or have narrow or semi narrow gap profiles. The fillet and U groove are prevalently used in heavy industries and shipbuilding to melt and join the parts. Since the wall thickness can be up to 6" or greater, welds must be made in many layers, each layer containing several passes. However, the welding time for the conventional processes such as SAW(Submerged Arc Welding) and FCAW(Flux Cored Arc Welding) can be many hours. Although SAW and FCAW are normally a mechanized process, pressure vessel and ship structures welding up to now have usually been controlled by a full time operator. The operator has typically been responsible for positioning each individual weld run, for setting weld process parameters, for maintaining flux and wire levels, for removing slag and so on. The aim of the system is to develop a high speed welding system with multitorch for increasing the production speed on the line and to remove the need for the operator so that the system can run automatically for the complete multi-torch multi-layer weld. To achieve this, a laser vision sensor, a rotating torch and an image processing algorithm have been made. Also, the multitorch welding system can be applicable for the fine grained steel because of the high welding speed and lower heat input compare to a conventional welding process.

• 약학회지
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• 제39권2호
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• pp.103-112
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• 1995

Population pharmacokinetics for gentamicin were compared with 24 American patients (16 male and 8 female) and 16 Korean-American appendicitis patients(12 male and 4 female). Two to six blood specimens were collected from all patients at the following times: just before a regularly scheduled infusion and at 1/2 hour after the end of a 1/2 hour infusion. Nonparametric expected maximum(NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant(K), the slope of the relationship between K versus creatinine clearance(KS), the apparent volume of distribution(V), the slope of the relationship between V versus weight(VS), gentamicin clearance(CL) and the slope of the relationship between CL versus creatinine clearance and the VS(CS). The output includes a 3-dimensional plot of the joint probability density function(PDF), two marginal PDF, means, medians, modes, variance, skewness, kurtosis, and CV%. The mean K(KS) were 0.424$\pm$0.139(0.00429$\pm$0.00164) and 0.411$\pm$0.135 hr$^{-1}$ (0.00475$\pm$0.00180[hr.mL/min/1.73m$^{2}]^{-1}$) for American and Korean-American populations, respectively. The mean V(VS) were not different at 15.6$\pm$4.77(0.233$\pm$0.0526) and 15.1$\pm$3.84L(0.239$\pm$0.0492 L/kg) for American and Korean-American populations, respectively (P>0.2). The mean CL (CS) were 6.28$\pm$1.85(0.0634$\pm$0.0191) and 5.70$\pm$1.77 L/hr(0.0701$\pm$0.0215 L/kg[hr.mL/min/1.73m$^{2}$)] for American and Korean-American populations, respectively. There are no differences in gentamicin pharmacokinetics between American and Korean-American Appendicitis patients.

• Steel and Composite Structures
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• 제23권4호
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• pp.453-464
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• 2017

The square tubed-reinforced concrete (TRC) column is a kind of special concrete-filled steel tube (CFST) columns, in which the outer thin-walled steel tube does not pass through the beam-column joint, so that the longitudinal steel reinforcing bars in the RC beam are continuous through the connection zone. However, there is a possible decrease of the axial bearing capacity at the TRC column to RC beam connection due to the discontinuity of the column tube, which is a concern to engineers. 24 connections and 7 square TRC columns were tested under axial compression. The primary parameters considered in the tests are: (1) connection location (corner, exterior and interior); (2) dimensions of RC beam cross section; (3) RC beam type (with or without horizontal haunches); (4) tube type (with or without stiffening ribs). The test results show that all specimens have relatively high load-carrying capacity and satisfactory ductility. With a proper design, the connections exhibit higher axial resistance and better ductility performance than the TRC column. The feasibility of this type of connections is verified.